Clinical trials: PERIODONTAL DISEASE
Immunodeficiency, Skeletal Abnormalities
European Alpha-Mannosidosis Participant
International, multicenter, observational, longitudinal monitoring study to investigate the prevalence of Alpha-Mannosidosis in participants at risk for Alpha-Mannosidosis.
- Conditions
- Immunodeficiency, Skeletal Abnormalities, Deafness, Mental Retardation
- Trial name
- EUMAP (NCT03651245)
- Where
- 19 sites in Germany, Switzerland
- Volunteers
- 667 people
- Sponsor
- CENTOGENE GmbH Rostock
Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC)
Assessment of Oral Health-Related Quality of Life in Preschool-Aged Children in Alto Alentejo
The observational study aims to improve understanding of Oral Health-Related Quality of Life (OHRQoL) among preschool children in the District of Portalegre, Portugal, by examining the roles of sociodemographic, behavioral, and…
- Conditions
- Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC), Traumatic Dental Injuries, Gingivitis
- Trial name
- NCT07648121
- Where
- Portugal
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Chronic Periodontitis
IgY Efficacy on Periodontitis Patients
Patients visiting National Hospital of Odonto-Stomatology for treating periodontitis used a food supplement (lozenge) containing chicken egg antibody (IgY) against Porphyromonas gingivalis gingipains as an adjunct to conventional…
- Trial name
- NCT02705885
- Testing
- lozenges containing IgY
- Volunteers
- 60 people
- Sponsor
- Immunology Research Institute in Gifu
Periodontitis (Stage 3)
Assessment of Autogenous Dentin Graft in Treatment of Infra-bony Defect
The aim of the present study was to evaluate the effect of demineralized autogenous dentine on treatment of infrabony defects.
- Trial name
- NCT05258006
- Testing
- Autogenous demineralized dentin nanoparticles
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- October 6 University
Caries, Tooth Decay
Improving Oral Health With Serious Games
This study investigated if computer games can be effective at changing the way children take care of their teeth. We a museum exhibit with 3D virtual reality games called "Attack of the S.
- Conditions
- Caries, Tooth Decay, Cavities, Gingivitis
- Trial name
- AOTSM (NCT02027597)
- Testing
- Attack of the S. Mutans, Follow-up, SnowWorld
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Washington
Atherosclerosis, Periodontitis
Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Periodontitis.
A randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment on endothelial dysfunction parameters in subjects with periodontitis and without any cardiovascular disease.
- Trial name
- NCT05906797
- Testing
- Non-surgical periodontal treatment by Q-SI, Non surgical periodontal debridement using MINST approach
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Catania
Periodontal Inflammation, Dental Malocclusion
Periodontal Parameters in Orthodontic Patients With Stainless Steel and Ceramic Brackets.
The aim of this study is to assess if there are significant differences in periodontal conditions between patients undergoing fixed orthodontic treatment with stainless steel or ceramic brackets.
- Trial name
- NCT05144555
- Testing
- Fixed orthodontic treatment with stainless steel brackets, Fixed orthodontic treatment with ceramic brackets
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Dental Pulp Necrosis, Periapical Periodontitis
Measurement of Bite Force in Humans
This protocol is for a clinical trial to evaluate the reliability of the bite fork as a diagnostic instrument in subjects with pulpal necrosis and apical periodontitis.
- Trial name
- NCT00223327
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Malocclusion, Angle Class II, Division 1
Evaluating Laser and Piezocision vs. Piezocision Alone on Root Resorption and Gingival Health During Tooth Retraction
This trial aims to determine whether using a special laser (low-level laser therapy, or LLLT) in combination with a minor surgical procedure (piezocision) can safely accelerate orthodontic treatment.
- Trial name
- NCT07442825
- Testing
- Flapless Corticotomy (Piezocision), Level Laser Therapy (LLLT), Traditional treatment
- Where
- Syria
- Volunteers
- 66 people
- Sponsor
- Damascus University
Gingivitis
"The Efficacy of Acacia Catechu Mouthrinse as Antiplaque and Antigingivitis Agent in Fixed Orthodontic Appliance Patients.
To study effect of acacia catechu a herbal extract;as antipaque and antigingivitis agent in patients with fixed orthodontic appliances.This study is a double blind randomized controlled trial.
- Trial name
- NCT02154594
- Testing
- Acacia catechu, Chlorhexidine gluconate, Distilled water
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Gingivitis, Plaque
Effectiveness of the GumChucks® Flossing System Compared to String Floss for Interdental Plaque Removal in Children
This study evaluates the interdental plaque removal efficacy, flossing speed, and reduction in gingival inflammation of a new flossing system (GumChucks®) compared to string floss, and to assess preference between the two…
- Trial name
- NCT04057430
- Testing
- GumChucks, String floss
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Caries,Dental, Pain
Comparative Evaluation of SMART Hall Technique Vs. Conventional SS Crown in Primary Molars: a Randomized Clinical Trial
Dental caries, particularly in primary molars, significantly affects children's oral health and overall well-being. Traditional management with stainless steel crowns (SSCs) involves significant tooth reduction and advanced…
- Conditions
- Caries,Dental, Pain, Plaque, Dental, Gingival Bleeding
- Trial name
- RCT (NCT06453005)
- Testing
- SMART Hall Technique or procedure
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- C K S Teja Institute Of Dental Sciences & Research
Allergic Rhinitis, Asthma in Children
Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma
The aim of the study was to evaluate if there were differences in oral findings between patients diagnosed with allergic rhinitis and/or asthma and a control group of health people.
- Conditions
- Allergic Rhinitis, Asthma in Children, Dental Caries, Periodontal Diseases
- Trial name
- NCT05576142
- Testing
- Oral examination
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Dental Malocclusion, Maxillary Deficiency
Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment
Research Question While the reduction in treatment times and the patient satisfaction after periodontally accelerated osteogenic orthodontics (PAOO) are well sustained in the scientific literature, there is still controversy…
- Trial name
- Piezo_Ortho (NCT06315348)
- Testing
- flapless alveolar decortication with augmentation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Gingivitis
Artificial Intelligence for the Diagnosis of Gingivitis
this study aims to use AI to diagnose the stages of gingivitis
- Trial name
- NCT07727421
- Testing
- Artificial intelligence Diagnostic Model
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Implantation, Peri-implant Mucositis
Evaluation of Peri-implant Conditions of Orthodontic Mini Implants
This observational study aims to evaluate the peri-implant conditions of mini implants placed during orthodontic treatment. Orthodontic mini implants are commonly used as temporary anchorage devices to prevent or reduce unwanted…
- Conditions
- Dental Implantation, Peri-implant Mucositis, Gingival Inflammation, Implant Stability
- Trial name
- NCT06491849
- Testing
- Peri-implant Condition Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Mehmet Selim Yildiz
Chronic Periodontitis
Effect of Ashwagandha on Salivary Antioxidant and Serum c Reactive Protein in Chronic Generalized Periodontitis
Periodontal disease is an immune-inflammatory disease which consists of connective tissue breakdown, loss of attachment, and alveolar bone loss.In normal physiology, there is an equilibrium maintained between reactive oxygen…
- Trial name
- NCT03533972
- Testing
- Ashwagandha
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Periodontal Diseases
Compare the Efficacy of Aloe Vera Mouthwash With Non- Alcoholic Chlorhexidine Mouthwash on Periodontal Diseases
Aim: To compare the efficacy of Aloe Vera and non-alcoholic chlorhexidine mouthwash in the treatment of Periodontal diseases. Methods \&Material: 32 patients were selected, the following periodontal parameters were recorded at…
- Trial name
- NCT02560870
- Testing
- Active Comparator:Aloe Vera mouthwash, Active Comparator:Chlorhexidine mouthwash
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Dental Anxiety, Tooth Loss
AntibaCterial presCribing & OraL Health Practice
A study by Allied Health Professionals to explore the experience of patients undergoing tooth extraction at Leeds Dental Institute in relation to antibiotic medication, dental anxiety and oral health practices
- Trial name
- ACCOLaDE (NCT04063696)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Leeds
Gingival Overgrowth
Diode Laser in Gingival Enlargement Related to Orthodontics
Gingival enlargement is one of the most common soft tissue problems associated with fixed orthodontic treatment. The presence of orthodontic appliances impedes oral hygiene measures and alters the oral microbial ecosystem to a…
- Trial name
- NCT01286298
- Testing
- Laser gingivectomy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong