Clinical trials: PERIODONTAL DISEASE
Dental Caries, Gingivitis
Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2).
In a previous study the efficacy of Lb CD2 on interim covariates related to caries development was tested. So, it was decided to plan a new study on schoolchildren from the same area.
- Trial name
- NCT01778699
- Testing
- lozenges
- Where
- Italy
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Rheumatoid Arthritis, Periodontitis
Relationship of Periodontitis and Cardiovascular Risk in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is one of the most common autoimmune inflammatory arthritis affecting 0.5 to 1% population worldwide characterized by synovitis, increased inflammatory markers and progressive bone and cartilage erosion.
- Trial name
- NCT03506165
- Testing
- Periodontal treatment
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Gingivitis, Bleeding Gum
Efficacy of Hyaluronic-acid and Hydrogen-Peroxide Mouthwash in Gingivitis Treatment
A clinical study to evaluate the efficacy and safety of a mouthwash containing Hydrogen Peroxide, Sodium Hyaluronate and Glycine in the prevention and management of complications associated gingivitis by film forming action.
- Trial name
- NCT04438421
- Testing
- Filming mouthwash formulation, enriched with Hydrogen Peroxide and Hyaluronic Acid, Chlorhexidine mouthwash
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Milan
Alveolar Clefts, Alveolar Bone Grafting
Evaluation of Using Iliac Crest With and Without Platelet-Rich Fibrin in Repair of Congenital Alveolar Cleft
A randomized clinical trial aims to evaluate the clinical and radiographic outcomes of the repair of congenital alveolar clefts using Iliac crest graft with and without mixing with platelet-rich fibrin
- Conditions
- Alveolar Clefts, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- NCT06924216
- Testing
- alveolar bone grafting, alveolar bone grafting Plus Platelet rich fibrin
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Suez Canal University
Allergic Rhinitis, Asthma in Children
Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma
The aim of the study was to evaluate if there were differences in oral findings between patients diagnosed with allergic rhinitis and/or asthma and a control group of health people.
- Conditions
- Allergic Rhinitis, Asthma in Children, Dental Caries, Periodontal Diseases
- Trial name
- NCT05576142
- Testing
- Oral examination
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Periodontitis, Diabetes Mellitus
Levels of Neuregulin-4 and Its Receptor ErbB4 in Periodontitis Patients With and Without Diabetes Type 2
The aim of this study is to assess the levels of neuregulin-4 and its receptor ErbB4 in the GCF and saliva in stage III and IV periodontitis patients with and without type 2 diabetes mellitus.
- Trial name
- NCT04930588
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Hygiene, Orthodontics
Impacts of Oral Irrigation in Orthodontic Patients
The present study aimed to investigate clinically the cleaning effectiveness of different treatment modalities, that is, oral irrigator or interdental brush usage addition to routine brushing and examine interleukin (IL)-1β…
- Conditions
- Oral Hygiene, Orthodontics, Periodontal Diseases
- Trial name
- NCT05562986
- Testing
- GCF (gingival crevicular fluid) collection
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ondokuz Mayıs University
Polycystic Ovary Syndrome, Periodontitis
Non-surgical Periodontal Therapy and Myo-inositol in Polycystic Ovary Syndrome Women Having Chronic Periodontitis
The Purpose of this study is to assess the correlation between the inflammatory periodontal status and the medical treatment status in Polycystic Ovary Syndrome(PCOS) women with systemic inflammation and to evaluate the effect of…
- Conditions
- Polycystic Ovary Syndrome, Periodontitis, Insulin Resistance
- Trial name
- NCT02633462
- Testing
- scaling and root planing , Myo-inositol, Myo-inositol
- Volunteers
- 56 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periapical Diseases, Root Canal Infection
Comparing Efficacy of a Stainless-steel Rotary File with Two Nickel-titanium Systems on Periapical Lesion Healing
Background: This study used cone-beam computed tomography (CBCT) to compare a stainless-steel Tornado file system with OneShape and WaveOne rotary systems for biomechanical canal preparation as indicated by the healing of…
- Trial name
- NCT06752837
- Testing
- Tornado rotary system, WaveOne rotary system, OneShape rotary system
- Where
- 2 sites in Lebanon
- Volunteers
- 60 people
- Sponsor
- Beirut Arab University
Pediatric Obesity, Pediatric Dentistry
Oral Health in Children and Adolescents With Obesity and Normal Weight
We aimed to compare the oral health status (dmft/DMFT index, IDCAS-II, BEWE, plaque index, gingival index, probing depth) between normal-weight (NW) and obese (OW) children/adolescents.
- Trial name
- NCT06283602
- Testing
- oral health status
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Periodontitis
Effects of Prebiotic Oral Healthcare Products as an Adjunct to Non-surgical Periodontal Therapy
The aim of this study is to determine the impact of a prebiotic toothpaste and mouthrinse in periodontitis patients as an adjunct to scaling and rootplaning.
- Trial name
- NCT02520375
- Testing
- Prebiotic, Control
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Miscarriage, Parodontitis
PERIodontal Disease, Microbiota and Miscarriage
Cross-sectional non-interventional observational pilot study recruiting women whom had repeated miscarriages (= at least 3 miscarriages).The information will be collected during a routine maintenance, complete oral clinical and…
- Trial name
- PERI2M (NCT06576622)
- Testing
- biological sampling
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Plaque Ph Lowering After Use of Probiotics, Caries
Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study
The aim of the present research protocol was to evaluate the effect of probiotics daily used, on the plaque acidogenicity of children.
- Conditions
- Plaque Ph Lowering After Use of Probiotics, Caries, Gingivitis
- Trial name
- NCT01601145
- Testing
- consumption of lozenges
- Where
- Italy
- Volunteers
- 192 people
- Sponsor
- Università degli Studi di Sassari
Gingival Health, Crowding of Anterior Mandibular Teeth
To Compare the Effects of Lip Bumper Appliance in Rate of Lower Incisor Alignment After First Premolar Extractions
The goal of this clinical trial is to check the effects of lip bumper appliance contribution to driftodontics after designated tooth extractions that are already part of orthodontic treatment plan.
- Trial name
- NCT06929754
- Testing
- Lip bumper
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bahria University
Periodontitis, Kidney Transplant Recipients
Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients
This randomized controlled trial evaluates the efficacy of diode laser-assisted non-surgical periodontal therapy in kidney transplant recipients with periodontitis.
- Trial name
- KTRs (NCT07532694)
- Testing
- Scaling and Root Planing, Diode Laser
- Where
- 2 sites in Vietnam
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Military Hospital 103
Peri-implant Mucositis, Peri-Implantitis
Chitosan Brushes vs Air-Abrasive Devices on Peri-implant Mucositis Treatment: A Randomized Clinical
Bleeding on probing (0,1,2,3), plaque index (+,-) and pocket probing depth will be recorded for each visit. Before the procedure, the patient will be randomly assigned to one of four groups and records will be kept.
- Conditions
- Peri-implant Mucositis, Peri-Implantitis, Bleeding on Probing, Periodontal Pocket
- Trial name
- NCT06287957
- Testing
- Labrida BioClean, EMS Handy 3.0 Perio Premium
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Apical Periodontitis, Trauma
Revitalization of Traumatized Immature Permanent Teeth
This study aims to assess the hypothesis that revitalization of teeth without (a)symptomatic apical periodontitis have a more favourable outcome in terms of further root development, periapical bone healing, maintaining/regaining…
- Trial name
- NCT06043453
- Testing
- revitalization
- Where
- Belgium
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Periodontitis, Vascular Disease
Vascular and Periodontal Disease - Microbial, Genetic and Histological Causalities
The purpose of this study is to analyze genetic polymorphisms in genes encoding pro-inflammatory cytokines, and study the genetic predisposition to chronic periodontitis (CP) in combination with atherosclerotic cardiovascular…
- Trial name
- NCT01358630
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Toothbrushing, Gingivitis
Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery
The study is a randomized clinical trial to compare the effectiveness of a dual light ultrasonic toothbrush on periodontal health in orthodontic patients undergoing surgery.
- Conditions
- Toothbrushing, Gingivitis, Cleft Lip and Palate
- Trial name
- NCT06122805
- Testing
- Toothbrush
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Dental Plaque
Effects of Fixed and Removable Space Maintainers on Periodontal Health and DMFT/Dft Values
Space maintainers are appliances that applied when primary teeth were lost prematurely because of many reasons such as tooth decay, trauma, lack of germ of permanent tooth.4 Space problems play an important role in practice of…
- Trial name
- NCT03608345
- Testing
- space maintainer
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Altinbas University