Clinical trials: PERIODONTAL DISEASE
Age Problem
Gingivitis Treated With Chlorhexidine 0.12% Mouthwash in Young Adults
The aim of this study will evaluate the effectiveness of 0.12% chlorhexidine solution as an anti-inflammatory agent and reducing the presence of biofilm in young adults.
- Trial name
- NCT04658225
- Testing
- 0.12% chlorhexidine
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
Gingival Diseases
Coronally Advanced Flap With Two Different Techniques for the Treatment of Multiple Gingival Recessions
This study compared the clinical outcomes of coronally advanced flap using two different surgical strategies in the treatment of multiple gingival recessions.
- Trial name
- NCT02229669
- Testing
- Horizontal incisions, Oblique incisions
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Paulista University
Gingivitis, PCOS
Effect of EE/NETA With Scaling on Periodontium and hsCRP in PCOS Women With Gingivitis
As gingivitis is known to add to the systemic inflammatory burden and may consequently contribute to progression of PCOS and vice-versa, So, controlling local and systemic inflammatory burden by scaling g and medical treatment…
- Trial name
- NCT05129878
- Testing
- scaling and OHI, oral Hygiene instructions, Scaling and oral hygiene instruction
- Where
- 2 sites in India
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontal Disease
Mental Health and Periodontitis in Probable Bruxers
The goal of this observational study is to learn how mental health affects periodontal health in people having teeth grinding (bruxism).
- Trial name
- NCT07634250
- Where
- India
- Volunteers
- 110 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Apical Periodontitis, Irreversible Pulpitis with Apical Periodontitis
To Measure Post Operative Pain Severity by Using Two Different Intra Canal Medicaments Calcium Hydroxide and Triple Antibiotic Paste in Teeth with Single Roots and Periapical Disease Called Apical Periodontitis
The aim of this study is to compare post operative pain effectiveness between two most commonly available intra canal medicaments that are Triple Antibiotic Paste and Calcium Hydroxide during root canal treatment of single rooted…
- Trial name
- NCT06821763
- Testing
- Calcium Hydroxide Intracanal medication, triple antibiotic paste (TAP)
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Komal Ashraf Khan
Plaque Induced Gingival Disease
Taste Acceptance and Effectiveness of Hyaluronic Acid and Chlorhexidine Mouthwashes in Children With Gingivitis
This randomized controlled clinical trial aims to compare the taste acceptance and clinical effectiveness of hyaluronic mouthwash and chlorhexidine mouthwash in children with plaque-induced gingivitis.
- Trial name
- NCT07662226
- Testing
- Hyaluronic Acid mouthwash, Chlorohexidine 0.12% mouthwash
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis
Tooth Loss in Periodontitis Patients
Tooth loss in periodontitis patients is associated with patient and site factors as well as with treatment provided. Not much is known about long-term tooth loss in periodontitis patients in private practice in the UK.
- Trial name
- NCT02091258
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- University College, London
Periapical Diseases
Research of the Application of Triple Antibiotic Paste in Primary Teeth With Pericpical Periodontitis
The triple antibiotic paste is widely used in young permanent teeth and permanent teeth root canal therapy with excellent antiantimicrobial effect.We hypothesize that its application in the treatment of periapical periodontitis…
- Trial name
- NCT02196740
- Testing
- Metronidazole-Ciprofloxacin gatifloxacin-Clindamycin paste, creosote
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Lin Jiacheng
Gingival Recession, Generalized
Comparison Between Connective Graft and Xenogeneic Matrix, in Patients With Multiple Gingival Recessions
Subepithelial connective tissue graft (SCTG) is considered the gold standard for root coverage treatment. However, it is associated with postoperative morbidity, limited amount of donor tissue, and longer surgical time.
- Trial name
- NCT03207984
- Testing
- Root coverage surgery
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Bone Atrophy, Alveolar
All-on-Four Implants With Ultrasonic
The objective of this observational study is the radiographic evaluation of marginal bone remodeling after surgical implant insertion in an immediate loading all-on-four technique with trans-sinusal titanium implants, correlating…
- Trial name
- Nobelsinus (NCT03357692)
- Testing
- all on four implant rehabilitation
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Periodontitis and Pregnancy
L. Reuteri ATCC PTA 5289 + L. Reuteri DSM 17938 in Pregnant Women
Randomized controlled tril to evaluate the safety and efficacy for the combination of L. reuteri ATCC PTA 5289 \& L. reuteri DSM 17938 in pregnant women with periodontitis and/or gingivits to improve oral health and at the same…
- Trial name
- NCT03375125
- Testing
- Probiotic
- Where
- 2 sites in Italy, Mexico
- Volunteers
- 300 people
- Sponsor
- Innovacion y Desarrollo de Estrategias en Salud
Periodontal Diseases, Chronic Periodontitis
Photodynamic Therapy During Supportive Periodontal Therapy
27 subjects on SPT, each with at least two residual pockets ≥5mm, were recruited for this randomised, split-mouth controlled trial, providing a total of 72 sites.
- Conditions
- Periodontal Diseases, Chronic Periodontitis, Periodontal Attachment Loss
- Trial name
- NCT02666573
- Testing
- Fotosan 630, CMS Dental, Copenhagen, Denmark, Scaling and root planing
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Caries, Gingivitis
School-based Oral Health Education Program Using Experiential Learning
The aim of this project was to compare the effectiveness of experiential learning (EL) and traditional lecturing (TL) school-based oral health education on the oral health knowledge, attitude, habits, oral hygiene, gingival…
- Trial name
- NCT02320162
- Testing
- Experiential learning oral health education
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Matina Angelopoulou
Diabetes Mellitus With Periodontal Disease
The Effect of Topical Doxycycline Gel on HbA1c in Patients With Type 2 Diabetes Mellitus(DM) ®
Aim: The purpose of this study is to investigate the effect of nonsurgical periodontal therapy plus subgingivally doxycycline gel 3% on glycemic control in type 2 diabetes mellitus (type 2 DM) patients who have periodontitis.
- Trial name
- NCT02735837
- Testing
- Doxycycline Group
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Amirhossein Farahmand
Gingival Diseases
Effects of Three Different Mouth Rinses on Dental Plaque in Children
Dental plaque is a major problem in the field of oral and dental health and its prevention is more important to avoid dental caries and gingival diseases.
- Trial name
- NCT06013735
- Testing
- sodium fluoride solution, guava leaves aqueous extract, pomegranate peel aqueous extrac
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Periapical Periodontitis
Periapical Healing After One or Two-visits to Endodontic Treatment in Adolescents Patients
The main objective of this study is the prevention and repair of apical periodontitis in lower molars with pulp necrosis after the execution of endodontic treatment in one or two visits in adolescent patients.
- Trial name
- PHAP (NCT01312194)
- Testing
- Root canal therapy in one visit, Root Canal Therapy in two-vist
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Wound Heal, Gingival Overgrowth
Different Platelet Concentrates After Gingivectomy and Gingivoplasty Evaluation of Its Effect on Early Wound Healing.
The aim of this study was to evaluate the effect of PRF, CGF and AFG application on early wound healing after gingivectomy and gingivoplasty operations.
- Conditions
- Wound Heal, Gingival Overgrowth, Gingival Enlargement, Platelet Rich Fibrin
- Trial name
- NCT04805463
- Testing
- Control group, PRF group, CGF group
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Inonu University
Tooth Loss, Dental Implant
A 36-month Analysis of the Clinical Performance of Individualized CAD/CAM-produced Dental Implants: a Cohort Study
The goal of this prospective cohort study is to evaluate the clinical performance of a new generation of customized CAD/CAM pre-fabricated root-analog dental implants over a 36-month period.
- Trial name
- NCT06576284
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Peri-implantitis
20-25 Year Follow-Up on Regenerative Bone Procedures for Peri-Implantitis
The goal of this 20-25-year observational study is to investigate the outcomes of bone regenerative surgery in peri-implantitis.
- Trial name
- periimpl20y (NCT06648564)
- Testing
- Bone regenerative surgery with a bone graft substitute and a resorbable membrane
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Kristianstad University
Gingival Recession Types One(RT1), Gingival Crevicular Fluid
Comparison of Connective Tissue and PRF in Gingival Recession
Aim: In this study, it was aimed to comparatively investigate the clinical and biochemical effects of subepithelial connective tissue graft and coronally advanced flap (SCTG + CAF) or titanium-prepared platelet rich fibrin and…
- Trial name
- NCT07877064
- Testing
- Titanium-prepared Platelet-Rich Fibrin, SCTG + CAF
- Volunteers
- 22 people
- Sponsor
- Ataturk University