Clinical trials: PTSD
Nightmares Associated With Trauma and Stress
Exposure, Relaxation, & Rescripting Therapy-Child
Untreated trauma-related nightmares and sleep-related disorders are associated with chronic health problems, burdening both the suffering individual and the health-care system.
- Trial name
- ERRT-C (NCT01776229)
- Testing
- Exposure, Relaxation, & Rescripting Therapy-Child
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Tulsa
Posttraumatic Stress Disorder, Depression
Controlled Trial of Early Intervention With Children and Adolescents Exposed to Nonrelational Traumatic Events
Background: International studies have shown that a substantial number of children and adolescents are exposed to potentially traumatic events.
- Conditions
- Posttraumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT02299583
- Testing
- Preventive intervention trauma-informed early intervention
- Where
- Denmark
- Volunteers
- 684 people
- Sponsor
- Carolina Magdalene Maier
Psychological Distress, PTSD
Boosting Refugee Integration Through Psychological Intervention
Refugees and asylum seekers (RAS) face numerous stressors and adversities which put them at risk for developing mental health problems. However, access to adequate mental health care in host countries is limited.
- Conditions
- Psychological Distress, PTSD, Trauma, Common Mental Health Problems
- Trial name
- BRIGHT (NCT06776523)
- Testing
- Problem Management Plus
- Where
- Switzerland
- Volunteers
- 1,200 people
- Sponsor
- University of Zurich
Posttraumatic Stress Disorder
Comparing Virtual Reality Therapy to Usual Treatment for PTSD
Combat related Posttraumatic Stress Disorder (PTSD) is the most common chronic psychiatric disorder in the veteran population. Unfortunately, outcome studies of VA PTSD programs have failed to show efficacy.
- Trial name
- NCT00167804
- Testing
- Virtual Reality Exposure
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- US Department of Veterans Affairs
Drug Use, Drug Abuse
Acute Intervention to Reduce Distress Following Sexual Assault
The purpose of this study was to evaluate whether a brief intervention in video format delivered in the post assault medical exam setting and including education about assault reactions and instruction in and modeling of…
- Conditions
- Drug Use, Drug Abuse, Posttraumatic Stress Disorder
- Trial name
- NCT01622855
- Testing
- PPRS
- Where
- United States
- Volunteers
- 442 people
- Sponsor
- Medical University of South Carolina
Child Sexual Abuse, Post-Traumatic Stress Disorder, PTSD
Intensive Inpatient Trauma-Focused Cognitive Behavioral Therapy (II-TF-CBT) for Adolescents With PTSD Following Sexual Abuse
This study looks at a treatment program for children and teens who have post-traumatic stress disorder (PTSD) after sexual abuse. The program is called II-TF-CBT.
- Trial name
- NCT07732335
- Testing
- II-TF-CBT
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Psychiatric Diagnosis, Schizophrenia Disorders
The Key to Integrated Trauma Treatment in Psychosis Trial
Schizophrenia spectrum disorders (SSDs) have a significant trauma etiology: trauma has been reported in 65 - 80% in this patient group and have a negative impact on prognosis.
- Conditions
- Psychiatric Diagnosis, Schizophrenia Disorders, Psychological Trauma, Historical
- Trial name
- KIT (NCT06608706)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) for psychosis
- Where
- 11 sites in Norway
- Volunteers
- 187 people
- Sponsor
- Haukeland University Hospital
Stress Disorders, Traumatic, Acute
Propranolol for the Treatment of Acute Stress Disorder
This 10-week study will examine whether propranolol, a medication that blocks the activity of the stress hormones adrenaline and noradrenaline, can relieve acute stress disorder (ASD) and symptoms from persisting long-term.
- Trial name
- NCT00069355
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Mental Health (NIMH)
Trauma-related PTSD
Considering Racial and Acculturation Stress in Addressing Trauma
Investigators plan to offer two evidence based interventions - Trauma Focused Cognitive Behavioral Therapy (CBT) (TF-CBT) and Trauma Systems therapy (TST) to traumatized children and their families.
- Trial name
- NCT05974176
- Testing
- Trauma Focused CBT (TF-CBT), Trauma Systems therapy (TST)
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- NYU Langone Health
Motivation, Alliance, Therapeutic
Animal-assisted Trauma-focused Therapy for Children and Adolescents
The study aims to investigate how the inclusion of an animal into a trauma-focused group therapy program (TF-CBT) affects therapy motivation of children and adolescents suffering from post-traumatic stress.
- Trial name
- AA TF-CBT (NCT05608551)
- Testing
- Animal-assisted trauma-focused therapy, Standard trauma-focused therapy
- Where
- 2 sites in Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Basel
Depression, Post-traumatic Stress Disorder
Evaluating Implementation Strategies to Scale-up Transdiagnostic Evidence-based Mental Health Care in Zambia
This study utilizes a Hybrid Type 1 multi-arm parallel group randomized control design to compare the effectiveness of an evidence-based treatment (CETA) delivered either in-person or via telephone, compared with a treatment as…
- Conditions
- Depression, Post-traumatic Stress Disorder, Anxiety, Substance Abuse
- Trial name
- NCT03458039
- Testing
- In-person CETA, Telephone CETA, Treatment as Usual (TAU)
- Where
- Zambia
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Psychopathic Personality Trait
Can Psychopathy be Prevented? Clinical, Neuroimaging and Genetic Data
The goal of this clinical trial was to learn about the effect of maltreatment on psychological and brain characteristics in a group of children.
- Trial name
- NCT06028620
- Testing
- Trauma Focused-Cognitive Behavior Therapy
- Where
- Mexico
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
PTSD, Substance Use Disorder (SUD)
Adolescent Stress and Substance Intervention Subsequent to Trauma
The long-term goal of this study is to address the adoption of the new trauma center requirement to establish best practices of screening for acute stress with an intervention to prevent both adolescent PTSD and substance use.
- Conditions
- PTSD, Substance Use Disorder (SUD), Acute Stress Disorder
- Trial name
- ASSIST (NCT07197476)
- Testing
- ASSIST Video Intervention
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Mood Lability, PTSD
FamilyLive Feasibility and Effectiveness Study
Children who have been exposed to trauma (defined as physical, sexual or emotional abuse, neglect, exposure to life threatening events, domestic and community violence, parental mental health disorders, substance abuse, and/or…
- Conditions
- Mood Lability, PTSD, Anxiety
- Trial name
- NCT01524185
- Testing
- FamilyLive, Standard Mental Health Treatment
- Where
- United States
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Posttraumatic Stress Disorder (PTSD)
Trajectories of Psychopathology in Response to NET
Narrative Exposure Therapy (NET) has been proven to be effective in the treatment of Posttraumatic Stress Disorder (PTSD) and trauma-related depression in more than a dozen controlled clinical trials.
- Trial name
- TOP-NET (NCT02852616)
- Testing
- Narrative Exposure Therapy
- Where
- Germany
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Stress Disorders, Post-Traumatic
Transcendental Meditation and Reduced Trauma Symptoms in Women Inmates
The pilot study investigates the potential benefits of the Transcendental Meditation program in reducing trauma, including PTSD, in female prisoners.
- Trial name
- NCT02791464
- Testing
- Transcendental Meditation program
- Volunteers
- 22 people
- Sponsor
- Maharishi International University
Pediatric Cancer, Follow-up Care
Coping and Post Traumatic Distress in Children and Adolescents During Cancer Follow-up Care
To explore the presence of post traumatic disorder and its association with coping strategies in children and adolescents during cancer follow-up care.
- Trial name
- NCT04908020
- Testing
- Follow-up patients
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Meyer Children's Hospital IRCCS
Mental Health Disorder, Post Traumatic Stress Disorder
Development of Mental Health Outcomes Following the 2020 Petrinja Earthquake
On 29 December 2020, an earthquake struck Petrinja in Croatia. The aim of this study is to assesses prevalence of symptoms of posttraumatic stress disorder, depression, anxiety, and panic disorder among exposed inhabitants and…
- Conditions
- Mental Health Disorder, Post Traumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT04911933
- Testing
- Family Therapy
- Where
- Croatia
- Volunteers
- 350 people
- Sponsor
- Neuropsychiatric Hospital dr Ivan Barbot
Posttraumatic Stress Disorder
Mind-Body Skills Groups for the Treatment of War-Related Trauma in Adolescents in Gaza
The objective of this study is to determine whether participation in a mind-body skills program by war-traumatized adolescents in Gaza will result in improvement of posttraumatic stress symptoms, depression, and levels of…
- Trial name
- NCT01595490
- Testing
- Mind-Body Skills Group
- Where
- Israel
- Volunteers
- 121 people
- Sponsor
- The Center for Mind-Body Medicine
COVID-19 Pandemic
A Coping and Resilience Intervention in Adolescents
The primary purpose of this study is to assess the feasibility and acceptability of a coping and resilience intervention for adolescents in school settings named CERIA, in the post-coronavirus disease 2019 or COVID-19 era.
- Trial name
- CERIA (NCT05830188)
- Testing
- Coping and Resilience Intervention for Adolescents, Printing materials of Coping and Resilience Intervention for Adolescents
- Where
- Indonesia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University