Clinical trials: Paediatric Surgery
Video-assisted, Head and Neck Surgery
Fiberoptic Intubation in Lateral Versus Supine Position in Pediatrics Undergoing Non-head-and-neck Surgery
Fiberoptic intubation was first described in the late 1960s and has since become an effective and well-established technique for airway management in awake, sedated, and anesthetized patients.
- Conditions
- Video-assisted, Head and Neck Surgery, Intubation
- Trial name
- NCT06776900
- Testing
- Supine position, Lateral position
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Tonsillectomy
Here's the Buzz: Evaluating Pediatric Post Op Pain and Nausea Following Tonsillectomy Surgery
Tonsillectomy is one of the most common surgeries performed in the United States, with over half a million performed annually in children younger than 15 years of age.
- Trial name
- NCT04910919
- Testing
- Honey, Standard of Care
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
General Anesthesia; Pediatric Surgery; Intraoperative Music Therapy; Operating Room Noise Reduction; Anesthetic Requirement; Analgesic Requirement
Effect of Intraoperative Instrumental Music and Operating Room Noise Reduction on Anesthetic and Analgesic Requirements in Pediatric Patients Aged 3-18 Years Undergoing Surgery Under General Anesthesia: A Randomized Controlled Trial
This randomized controlled clinical trial aims to evaluate the effects of intraoperative instrumental music and operating room noise reduction on anesthetic and analgesic requirements in pediatric patients aged 3-18 years…
- Trial name
- MUSIC-OR (NCT07630675)
- Volunteers
- 180 people
- Sponsor
- Ankara City Hospital Bilkent
Tracheal Intubation, Videolaryngoscopy
Video Versus Direct Laryngoscopy for Tracheal Intubation in Pediatric Surgery
Tracheal intubation in paediatric patients is a high-risk procedure in which failure to achieve successful intubation on the first attempt is associated with an increased risk of complications, including hypoxaemia and airway…
- Conditions
- Tracheal Intubation, Videolaryngoscopy, General Anesthesia, Difficult Airway Intubation
- Trial name
- VIDEOKIDS (NCT07495436)
- Testing
- Videolaryngoscope, Direct Laryngoscope
- Where
- Spain
- Volunteers
- 5,562 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Appendectomy, Laparoscopy
TAP Block or Wound Infiltration for Laparoscopic Pediatric Appendectomy: a Pilot Study
Effectiveness of the TAP block compared to wound infiltration in controlling pain after laparoscopic appendectomy in children
- Conditions
- Appendectomy, Laparoscopy, Anesthesia, Conduction, Child, Preschool
- Trial name
- NCT04294537
- Testing
- TAP Block, LIA local infiltration, General anesthesia
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Ospedale di Circolo - Fondazione Macchi
Children With Heart Defects
Heparin Responses in Pediatric Patients Undergoing Cardiopulmonary Bypass.
Heparin is an anticoagulant or "blood thinner". Heparin is always given to patients undergoing open-heart surgery to prevent blood from clotting when a patient is placed on the heart-lung machine.
- Trial name
- NCT00166140
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Emory University
Anesthesia, Local, Postoperative Pain
Comparison of Supraclavicular and Costoclavicular Brachial Plexus Blocks in Pediatrics
In upper extremity surgeries, the brachial plexus block can be performed with different techniques at various levels depending on the proximal and distal level of the surgery.
- Trial name
- NCT04782778
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Preoperative Anxiety Experienced by the Pediatric Patient, Preoperative Anxiety
Comparing Two Doses of Midazolam With Added Dexmedetomidine for Kids Before Surgery
The goal of this randomized controlled trial is to investigate if adding intranasal dexmedetomidine to two different doses of intranasal midazolam provides effective sedation with fewer side effects in pediatric patients aged 1…
- Trial name
- NCT06979791
- Testing
- Dexmedetomidine + Midazolam 0.4 mg/kg, Dexmedetomidine + Midazolam 0.2 mg/kg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Hypospadias, Distal Penile Hypospadias (Disorder)
Effect of Adding Byar's Flap to Double Dartos Coverage in TIP Urethroplasty for Distal Hypospadias: A Randomized Trial
This randomized controlled trial evaluates the effect of adding Byar's flap in combination with double dartos flap coverage during tubularized incised plate (TIP) urethroplasty in children with distal hypospadias.
- Trial name
- DD-TIP-BF (NCT07525570)
- Testing
- Double Dartos Flap Coverage, Byar's Flap + Double Dartos Flap
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Javaid Afridi
Hirschsprung Disease, Febrile Urinary Tract Infection (Disorder)
Does Hirschsprung Disease Increase the Risk of Febrile Urinary Tract Infection in Children
Febrile urinary tract infection (FUTIs) are the most common bacterial infections in children under the age of 2 years. They represent 7% of children presenting with fever without a source.
- Trial name
- NCT04837963
- Where
- France
- Volunteers
- 630 people
- Sponsor
- University Hospital, Montpellier
Pediatrics, Anesthesia
Papaverine vs Heparin for Peripheral Arterial Catheter Patency in Pediatric Patients
The purpose of this study is to compare intraoperative papaverine plus heparin to heparin alone for prevention of arterial spasm and maintenance of patency of peripheral arterial catheters during surgery in pediatric patients.
- Conditions
- Pediatrics, Anesthesia, Vasospasm
- Trial name
- NCT03894904
- Testing
- Papaverine, Heparin, Rescue papaverine, as needed
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cleft Lip and Palate
Use of Computer Aided Design and 3D Printing for Anesthesiology Management in a Pediatric Patient With Cleft Facial Defect (3D Obturator) - Pilot Trial
Congenital malformations of the orofacial area are the most common congenital malformations in children with an incidence of 1.8 children with orofacial cleft per 1000 healthy births in the Czech Republic.
- Trial name
- Pilobtur (NCT04422964)
- Testing
- 3D Obturator
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Brno University Hospital
General Anesthesia
Gastric Ultrasound in Paediatric Anaesthesia
Anesthesia for emergency surgery is a situation at risk of pulmonary aspiration of gastric contents. It has been previously reported that bedside two-dimensional ultrasonography can be a useful tool for anesthesiologists to…
- Trial name
- ECHOGASTRO (NCT02584348)
- Testing
- Gastric ultrasound
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Hospices Civils de Lyon
Post Operative Pain
Dexametomedine Versus Ketamine as an Adjuvant in Erector Spinae Block for Perioperative Thoracotomy Pain Control
A double-blind randomized control study to compare the efficacy of dexmedetomidine versus ketamine as an adjuvant in combination with bupivacaine ultrasound-guided ESP block in patients scheduled for cardiothoracic surgeries with…
- Trial name
- NCT05552391
- Testing
- Bupivacaine, Ketamine Hydrochloride, Dexmedetomidine Hydrochloride
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Kasr El Aini Hospital
Optic Nerve Sheath Diameter, Caudal Block
Effect of Caudal Block Injection Rate on Optic Nerve Sheath Diameter in Pediatric Surgeries
Our prospective observational study will include patients between the ages of 1-7 years, ASA 1-2, who will undergo elective surgery under general anesthesia, whose consent was obtained by their parents for the procedure to be…
- Trial name
- NCT06187714
- Testing
- caudal block rate
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Intubation, Pediatric Surgery
Cuffed Versus Uncuffed Tracheal Tubes in PICU (PICU-BG-TT Study)
The CDC definition was used to identify patients with VAP and VAT. The CDC definition of VAP for infants < 1 y.o. and children > 1 or < 12 y.o. are based on clinical and X-ray criteria.
- Trial name
- PICU-BG-TT (NCT03129893)
- Testing
- Cuffed tracheal tubes
- Where
- Italy
- Volunteers
- 242 people
- Sponsor
- FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
Regional Anesthesia Morbidity, Hip Surgeries
Pericapsular Nerve Group Block vs. Fascia Iliaca Compartment Block vs. Caudal Block for Hip Surgeries
The study aims to compare the effect of pericapsular nerve group block versus fascia iliaca compartment block versus caudal block regarding Postoperative analgesia in children undergoing hip surgeries.
- Conditions
- Regional Anesthesia Morbidity, Hip Surgeries, Perioperative Analgesia
- Trial name
- NCT07137962
- Testing
- PENG Block, FICB Block, Caudal Block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ulnar and Radial Artery
Ultrasonographic Evaluation of Arteries of the Hand in Pediatric Patients
Ultrasound measurements of the ulnar artery and radial artery at different angles are obtained and compared to determine the optimal diameters for possible arterial cannulation in pediatric patients.
- Trial name
- NCT06386718
- Where
- Turkey (Türkiye)
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Ankara University
Appendicitis
Antimicrobial Stewardship in Pediatric Surgery
Acute appendicitis is a common surgical emergency in children. Non-perforated appendicitis patients do not require antibiotics after appendectomy.
- Trial name
- AbxPS (NCT02270996)
- Testing
- Antimicrobial Stewardship Program
- Volunteers
- healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Ondansetron Lozenge, Postoperative Nausea and Vomiting
Preoperative Ondansetron Lozenge for Prevention of Postoperative Nausea and Vomiting in Pediatrics Undergoing Squint Surgeries
The aim of this study is to evaluate the role of ondansetron lozenge on prevention of postoperative nausea and vomiting (PONV) in pediatrics undergoing squint surgeries.
- Conditions
- Ondansetron Lozenge, Postoperative Nausea and Vomiting, Pediatrics, Squint
- Trial name
- NCT06423820
- Testing
- Ondansetron lozenge
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University