Clinical trials: Paediatric Surgery
Hirschsprung Disease, Febrile Urinary Tract Infection (Disorder)
Does Hirschsprung Disease Increase the Risk of Febrile Urinary Tract Infection in Children
Febrile urinary tract infection (FUTIs) are the most common bacterial infections in children under the age of 2 years. They represent 7% of children presenting with fever without a source.
- Trial name
- NCT04837963
- Where
- France
- Volunteers
- 630 people
- Sponsor
- University Hospital, Montpellier
Hemodynamic
Use of the Aortic Time-velocity Integral Via Suprasternal Ultrasound to Search Preload Dependence in Paediatric Surgery : Kid's Fluid Management (FM)
After major surgery, fluid overload is associated with an increase of morbidity and mortality. Fluid administration should therefore be given wisely.
- Trial name
- Kid's FM (NCT07099664)
- Testing
- Measurement of aortic Vmax and VTI with suprasternal doppler.
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Lille
Pediatric Surgery, Health Literacy
Health Literacy in the Perioperative Setting
The purpose of this study is to determine the association of the social determinants of health with perioperative health literacy in caregivers of children presenting for surgery.
- Trial name
- NCT07138482
- Testing
- Survey using a questionnaire.
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Brittany Willer
Child, Only
Pediatric Ultrasound-guided Dorsal Penile Nerve Block Plus Sedation in Spontaneous Breathing
One of the most frequent surgical procedures in the pediatric population is circumcision, following which postoperative pain could be stressful.
- Trial name
- NCT04475458
- Testing
- Ultrasound-guided dorsal penile nerve block
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Tumor, Solid, Neuroblastic Tumors
Interest of Preoperative Arteriography to Identify the Adamkiewicz Artery Before Surgery for Basi-thoracic Neuroblastic Tumors
Neuroblastic tumors (NBTs) develop from neural crest cells that give rise to the sympathetic nervous system. They include neuroblastomas, ganglioneuroblastomas, and ganglioneuromas.
- Conditions
- Tumor, Solid, Neuroblastic Tumors, Neuroblastoma
- Trial name
- AKA-NBL (NCT06798532)
- Testing
- Collection of data from the patient's medical file.
- Where
- 27 sites in France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Surgical Procedure, Unspecified
TFPB vs QLB III in Infra-umbilical Pediatric Surgeries
Regional anesthetic techniques; they reduce postoperative morbidity, provide early mobilization and provide great advantages by significantly reducing the need for narcotic analgesics.
- Trial name
- NCT05671484
- Testing
- Transversalis Fascial Plane Block, Quadratus Lumborum Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Namik Kemal University
Liver Diseases
TachoSil Paediatric Liver Trial (TC-019-IN)
The overall objective is to assess the haemostatic efficacy and safety of TachoSil for control of local bleeding in paediatric patients undergoing surgical resection of the liver with our without segmental liver transplantation.
- Trial name
- NCT00365248
- Testing
- Fibrinogen human (TachoSil)
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Nycomed
Analgesia, Surgical Procedure, Unspecified
Virtual Reality Games in Pediatric Surgery
Randomized controlled trial reporting the pain levels and pain control/reduction of children at the age of 6-15 undergoing surgical procedures by using virtual reality gaming (VR) compared to nitrous oxide.
- Conditions
- Analgesia, Surgical Procedure, Unspecified, Immersion
- Trial name
- NCT05510141
- Testing
- Virtual reality gaming, Nitrous oxide
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pain, Chronic, Pain, Chronic Post-Surgical
iCanCope With Post-Operative Pain (iCanCope PostOp)
There are few applications available in the community to help teenagers manage pain after surgery. The focus of this study is to better understand the pain experience of children after having surgery and to design a Smartphone…
- Trial name
- NCT05382962
- Testing
- iCanCope Post Op Application
- Where
- 2 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- The Hospital for Sick Children
Circumlocution, Children
Intelligent Customer-driven Solution for Pediatric Surgery Care for Parents and Their Children Undergoing Circumcision
This study aims to (1) develop an intelligent customer-driven solution for pediatric surgery care for parents of children undergoing circumcision and their children; (2) examine the effectiveness of the intervention on outcomes…
- Conditions
- Circumlocution, Children, Surgery, Parents
- Trial name
- NCT04174404
- Testing
- ICory-Circumcision, Routine care
- Where
- Singapore
- Volunteers
- 160 people
- Sponsor
- HE Hong-Gu
Cleft Lip and Palate
Evaluation of the Effects of LUNII on Pre-operative Anxiety and on the Post-operative Period in Children With Cleft Lip and Palate Admitted for Alveolar Bone Graft: Pilot Study
The literature on the effects of various devices on per-operative anxiety is scarce. There is currently no study on the effects of an interactive storyteller on per-operative anxiety in pediatric surgery.
- Trial name
- LUNII (NCT03740841)
- Testing
- Interactive story teller LUNII
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ventilator Lung, Surgery
Monitoring of Lung Ventilation Through Electrical Impedance Tomography During Pediatric Surgery
Given the scarcity of studies aimed at assessing the effect of anesthesia and m ventilation on the distribution of lung ventilation in pediatric patients undergoing surgery, with the exclusion of thoracic surgery, the present…
- Conditions
- Ventilator Lung, Surgery, Pediatric
- Trial name
- VentiPed (NCT06370507)
- Testing
- Electrical impedance tomography assessment of ventilation distribution in course of sedation/general anesthesia for pediatric surgery
- Volunteers
- 800 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Blood Coagulation Disorders, Hemorrhage
Fibrinogen for Treatment of Pediatric Dilutional Coagulopathy. FibPaed Study.
The purpose of this study is to compare two different thromboelastometry (ROTEM) trigger levels for administration of human fibrinogen concentrate (Haemocomplettan P) in the treatment of perioperative dilutional coagulopathy…
- Trial name
- NCT01487837
- Testing
- Human fibrinogen concentrate
- Where
- Switzerland
- Volunteers
- 57 people
- Sponsor
- University Children's Hospital, Zurich
Cardiopulmonary Bypass, Congenital Heart Defects
SPY Imaging System: Its Role in Pediatric Cardiac Surgery
The current method of evaluating the surgical repair during surgery is limited to echocardiography (a noninvasive diagnostic procedure that uses ultrasound to study the structure and motions of the heart) or an invasive procedure…
- Trial name
- NCT00446927
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Emory University
Spinal Deformity, Paediatric Surgery, Tranexamic Acid
Topical Tranexamic Acid in Major Paediatric Spine Deformity Surgery: A Randomized Controlled Trial
Our study will evaluate the use of topical and intravenous (IV) Tranexamic Acid (TXA) in spine surgery. The purpose of TXA is to prevent clotting during surgery to reduce blood loss.
- Trial name
- NCT02093988
- Testing
- Topical TXA, Intravenous TXA
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of British Columbia
Opioid Use
Pupillometry-guided Remifentanil Infusion Versus Conventional Administration in Children
Our study aims to compare the total intravenous dose of remifentanil per anesthesia hour and body weight in two groups of pediatric surgical patients - an interventional group with remifentanil infusion under pupillometry…
- Trial name
- PURFT (NCT03749811)
- Testing
- Pupillometry
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Wound Infections
Antimicrobial Coated Sutures in Paediatric Surgery
The purpose of this study is to determine if suture material coated by antimicrobial agent triclosan would decrease the incidence of surgical site infections (SSIs) in paediatric surgery compared to ordinary sutures.
- Trial name
- NCT01220700
- Testing
- Triclosane, Control
- Where
- Finland
- Volunteers
- 1,635 people
- Sponsor
- University of Oulu
Chronic Pain
A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children
The purpose of this study is to investigate the prevalence, risk factors and consequences of chronic post-surgical pain in children aged 0-16 years through a number of questionnaires completed at various timepoints, from before…
- Trial name
- POPSICLE (NCT06354699)
- Where
- 16 sites in United States, Australia and 2 more
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Telethon Kids Institute
Fasting
Parents Perception and Compliance With Pre Operative Fasting Instructions in Paediatric Patients
This study evaluates the perception and compliance with the fasting instructions given to parents of children undergoing surgery.
- Trial name
- NCT03606564
- Testing
- study of fasting time among pediatric patients undergoing day care surgery
- Where
- India
- Volunteers
- 1,050 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pain
Oral vs IV Acetaminophen for Long-bone Fracture in Children
Intravenous (IV) acetaminophen entered the Canadian market recently and children with acute pain following a trauma are ideal candidates for the IV formulation as it may improve analgesia and consequently decrease the amount of…
- Trial name
- NCT05557344
- Testing
- Acetaminophen IV, Acetaminophen
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Dr. Niina Kleiber