Clinical trials: Paediatric Surgery, open to volunteers
Enhanced Recovery After Surgery, Gynecologic Disease
ERAS in Pediatric & Adolescent Gynecology Preoperative Counseling
The Investigator propose a randomized trial that will assess whether participant involvement in pre-operative counseling for ERAS improves post-surgical pain scores.
- Trial name
- NCT04963751
- Testing
- Enhanced Recovery After Surgery (ERAS) Counseling to Patients, Enhanced Recovery After Surgery (ERAS) Counseling to Caregiver
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Cryo Analgesia, Pectus Surgery
Long Term Safety of Preoperative Percutaneous Intercostal Cryoneurolysis
Follow up of patients who underwent percutaneous cryoneurolysis for pectus excavatum repair (the Nuss procedure) pain management
- Trial name
- CRYOFUP (NCT07657845)
- Testing
- Self-report Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) Questionnaire - Pediatric Quality of Life Inventory (PedsQL™) Questionnaire - Patient Self-Assessment Sensory Scale
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Papa Giovanni XXIII Hospital
Postoperative Care, Analgesia Assessment
Posthectomy in Pediatric Elective Surgery : a Comparison of Perioperative Analgesia Using Echo-guided Penile Block and Pudendal Block With neurostimuLation Technique
Context : Posthectomy is a surgical procedure that concerns around 30% of the male population, mainly in pediatrics. As this procedure is mainly performed on an outpatient basis, the implementation of an enhanced rehabilitation…
- Conditions
- Postoperative Care, Analgesia Assessment, Posthectomy, Postoperative Analgesia
- Trial name
- PinEAPPLE (NCT07191938)
- Testing
- Ultrasound guided penile block, Neurostimulation guided pudendal block
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Caen
Appendicitis, Acute, Appendectomy
Video-Based Grading of Intraoperative Adverse Events in Pediatric Laparoscopic Appendectomy
Acute appendicitis is the most common surgical emergency in children, and laparoscopic appendectomy is its standard treatment. Although intraoperative adverse events (iAEs) are recognized as an important determinant of surgical…
- Conditions
- Appendicitis, Acute, Appendectomy, Intraoperative Complications, Patient Safety
- Trial name
- PedAppy-iAE (NCT07794618)
- Testing
- Laparoscopic appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ahmet Burak Doğan, MD
Musculoskeletal Deformity, Musculoskeletal Diseases
Customized Bone Allografts by 3D-printing
Virtual surgical planning (VSP), the simulation of bone corrections in virtual reality ("Computer Aided Surgical Simulation": CASS) and 3D printing of customized implants and devices are achieving an increasingly central role in…
- Conditions
- Musculoskeletal Deformity, Musculoskeletal Diseases, Musculoskeletal Disorder
- Trial name
- 3D-MALF 2 (NCT05700526)
- Testing
- Planning of multiplanar and/or multifocal osteotomies in children by using VSP, PSIs and customized structural bone allograft, Routine preparation of bone graft according to standard protocols, Preparation of bone graft with virtual bone-matching and GSIs
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Istituto Ortopedico Rizzoli
Cardiac Surgery, Extracorporeal Circulation; Complications
Evaluation of Blood and Cardiac Protein O-GlcNAcylation Levels in Cardiac Surgery in Children
Cardiac surgery requires the use of extracorporeal circulation (ECC). Age-related differences in inflammatory response, the greater susceptibility of immature organ systems to injury and the larger ratio of extracorporeal…
- Conditions
- Cardiac Surgery, Extracorporeal Circulation; Complications, Metabolism, Low Cardiac Output
- Trial name
- CardiOGlcNAc (NCT06754709)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Nantes University Hospital
Strabismus, Esotropia
Risk Factors And Surgical Outcomes Of Strabismus Reoperation
Horizontal strabismus, commonly known as inward or outward deviation of the eyes, is a frequent eye condition that may require surgical correction.
- Conditions
- Strabismus, Esotropia, Exotropia
- Trial name
- RSOR (NCT07446621)
- Testing
- Horizontal Strabismus Reoperation
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
General Anesthesia; Pediatric Surgery; Intraoperative Music Therapy; Operating Room Noise Reduction; Anesthetic Requirement; Analgesic Requirement
Effect of Intraoperative Instrumental Music and Operating Room Noise Reduction on Anesthetic and Analgesic Requirements in Pediatric Patients Aged 3-18 Years Undergoing Surgery Under General Anesthesia: A Randomized Controlled Trial
This randomized controlled clinical trial aims to evaluate the effects of intraoperative instrumental music and operating room noise reduction on anesthetic and analgesic requirements in pediatric patients aged 3-18 years…
- Trial name
- MUSIC-OR (NCT07630675)
- Volunteers
- 180 people
- Sponsor
- Ankara City Hospital Bilkent
Undescended Testis
Comparison of Single Incision Scrotal vs Standard Two Incision Inguinal Orchidopexy in Children Under 10 Years.
This study compares the outcome of single incision scrotal orchidopexy with standard two incision inguinal orchidopexy in children under 10 years of age presented with palpable undesended tesis.The aim is to evaluate operative…
- Trial name
- NCT07233265
- Testing
- Single scrotal incision orchidopexy, Standard two incision inguinal orchidopexy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Children Hospital Faisalabad
Sedation, Preoperative Anxiety Experienced by the Pediatric Patient
Children of Age 2-6years Undergoing Elective Surgery Will be Divided Into Two Groups Randomly. This Study Aims to Evaluate if Intranasal Dexmedetomidine is Better Than Intranasal Ketamine in Producing Sedation and Reducing Parent Separation Anxiety Before Surgery.
This study aims to compare intranasal dexmedetomidine versus intranasal ketamine as a premedication in children undergoing surgery in our population.
- Conditions
- Sedation, Preoperative Anxiety Experienced by the Pediatric Patient, Anxiolytic Effect, Sedation and Analgesia
- Trial name
- DREAM-Kids (NCT07180095)
- Testing
- Intranasal dexmedetomidine, Intranasal ketamine
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Pediatric Sedation, Clonidine Sedation
Premedication in Children: a Clinical Trial Comparing Oral Ketamine and Oral Clonidine With Respect to Sedation Level and Opioid Consumption in Pediatrics Undergoing Elective Lower Abdominal Day-case Surgery.
Aim of the work Is to compare between oral ketamine and oral clonidine regarding the level of sedation pre and postoperatively in addition the need of opioids administration intraoperative in children undergoing elective lower…
- Conditions
- Pediatric Sedation, Clonidine Sedation, Ketamine Sedation
- Trial name
- NCT07461376
- Testing
- Oral Clonidine (OC)
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cairo University
Shoulder Pain
Pneumoperitoneum Management With SurgiQuest AirSeal® at Low vs. Higher Pressure
A prospective, randomized, controlled single-center clinical Study designed to evaluate Physician Preference related to the use of the SurgiQuest AirSeal® Insufflation System (AIS) at low vs.
- Trial name
- PRESSURE (NCT02837601)
- Testing
- AirSeal® Insufflation System (AIS)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Akron Children's Hospital
Stress Response
Effect of Nebulized Lignocaine on the Stress Response of Endotracheal Intubation in Pediatrics Undergoing Tonsillectomy Operation Monitored by Rise in Serum Cortisol Level Post Intubation
This randomized clinical trial aims to is examining the effect of preoperative nebulized lidocaine on the stress response to intubation, monitored by rise in serum cortisol level post intubation
- Trial name
- NCT07139730
- Testing
- Lignocaine 2% concentration solution
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Endotracheal Extubation, Airway Anesthesia
BELUGA: Better to Exchange ETT for LMA Before Extubation in Children Under General Anaesthesia
During surgery, anaesthetists can use an endotracheal tube (ETT) to facilitate ventilation. At emergence from general anaesthesia, there are two techniques for removal of the ETT: (1) the ETT is removed when the child is waking…
- Conditions
- Endotracheal Extubation, Airway Anesthesia, Paediatric
- Trial name
- BELUGA (NCT07204990)
- Testing
- Direct removal of endotracheal tube, Laryngeal mask airway inserted following deep extubation
- Where
- 8 sites in United States, Australia and 4 more
- Volunteers
- 1,400 people
- Sponsor
- Telethon Kids Institute
Pancreatic Duct Stenting, ERCP
Management of Pediatric Pancreatic Calculi At a Single Center: a Retrospective Cohort Study
The goal of this observational study is to evaluate the long-term effects of ERCP and surgery in pediatric patients with pancreatic duct stones.
- Conditions
- Pancreatic Duct Stenting, ERCP, Surgery in Early Childhood, Pediatric Surgery
- Trial name
- NCT06900790
- Testing
- ERCP
- Volunteers
- 60 people
- Sponsor
- Yifan Deng
Robotic System, Pediatric
Use of the Single Port Robotic System in Pediatric Surgery
Open surgery (laparotomy) has long been the gold standard for pediatric surgery. The development of laparoscopy in the 1980s reduced post-operative pain. Since the 2000s, robotic surgery has been on the rise.
- Conditions
- Robotic System, Pediatric, Surgery in Children
- Trial name
- SPCHIRPED (NCT07660497)
- Testing
- Singleport robotic system to treat minors
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Digital Literacy, Pediatric Surgery
Digital Literacy in Caregivers of Pediatric Surgery Patients
The purpose of this study is to describe the digital literacy of caregivers of pediatric surgical patients. The investigators hypothesize that caregivers of minority race, language of care other than English, and low neighborhood…
- Trial name
- NCT07060326
- Testing
- Survey using a questionnaire.
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Brittany Willer
Postoperative Pain, Pediatric Open Heart Surgery
A Combination of Intrathecal Fentanyl and Pecto-Intercostal Fascial Block in Paediatric Cardiac Surgery.
Cardiac surgery is commonly performed via median sternotomy. Patients undergoing cardiac surgical procedures frequently experience intense acute pain in the post-sternotomy wound, which can potentially transition into persistent…
- Trial name
- NCT06882655
- Testing
- PIFB group, Intrathecal fentanyl(IT fentanyl), IT + PIFB
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Alexandria University
Perioperative Anxiety
Sensory Toys for Anxiety Reduction - Can Fidget Toys Improve Stress and Help Children to Cope Before Surgery (STARFISH)
Anxiety associated with medical procedures is common, with 40-80% of children experiencing significant symptoms and postoperative consequences, including distress and delirium, increased intensity/duration of pain, prolonged…
- Trial name
- STARFISH (NCT07270029)
- Testing
- Pre-operative sensory toy, Post-operative sensory toy
- Where
- 2 sites in Australia, Brazil
- Volunteers
- 500 people
- Sponsor
- Telethon Kids Institute
Pediatric Surgery, Health Literacy
Health Literacy in the Perioperative Setting
The purpose of this study is to determine the association of the social determinants of health with perioperative health literacy in caregivers of children presenting for surgery.
- Trial name
- NCT07138482
- Testing
- Survey using a questionnaire.
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Brittany Willer