Clinical trials: Pain, Eye
Dental Anxiety, Pain
Effectiveness of Hand/Eyes/Mouth Behavior Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this studio will be to evaluate the effectiveness of "Hands/Eyes/mouth" behavior management technique versus a conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02591797
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Cardenal Herrera University
Behavior, Child, Dental Anxiety
Pain and Anxiety Reduction Using a Vibrating Eye Massage Device With Relaxing Nature Sounds
This study aims to evaluate the effectiveness and acceptance of an eye massage device that produces nature sounds and vibratory stimulations in the management of anxious pediatric patients during inferior alveolar nerve block…
- Conditions
- Behavior, Child, Dental Anxiety, Anesthesia, Local
- Trial name
- NCT05592587
- Testing
- Evaluation of the effectiveness of eye massage device producing both vibrations and nature sounds distraction in the management of anxious pediatric patients during inferior alveolar nerve., Evaluation of the effectiveness of eye massage device producing vibratory stimulations distraction in the management of anxious pediatric patients during inferior alveolar nerve., Evaluation of the effectiveness of basic behavior guidance techniques without using any type of distraction aids in the management of anxious pediatric patients during inferior alveolar nerve.
- Where
- Syria
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Damascus University
ALS, Autism Spectrum Disorder
Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products
This is an observational study of medical marijuana manufactured and dispensed by Ilera and given as standard treatment for a variety of approved serious medical conditions as defined by individual state law.
- Conditions
- ALS, Autism Spectrum Disorder, Cancer, Spasticity, Muscle
- Trial name
- Ilera (NCT03886753)
- Testing
- Registry, PK microsampling of blood
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Organic, Including Symptomatic, Mental Disorders, Substance Use
Exploring the Comorbidity Between Mental Disorders and General Medical Conditions
Mental disorders have been shown to be associated with a number of general medical conditions (also referred to as somatic or physical conditions).
- Conditions
- Organic, Including Symptomatic, Mental Disorders, Substance Use, Schizophrenia, Mood [Affective] Disorders
- Trial name
- COMO-GMC (NCT03847753)
- Testing
- Organic Disorders, Substance Use Disorders, Schizophrenia Disorders
- Volunteers
- 5,940,299 people
- Sponsor
- University of Aarhus
MCS vs ReLACS, Pain Perception Postoperatively First Eye vs Second Eye
A Comparison of Patient Perceptions Undergoing Manual Cataract Surgery (MCS) vs Refractive Laser-assisted Cataract Surgery (ReLACS) in First and Second Eyes
The focus of this study is to assess how pain can be mitigated for patients undergoing cataract surgery through the early application of anesthesia prior to the surgery as compared to the standard timing, and by using the ReLACS…
- Conditions
- MCS vs ReLACS, Pain Perception Postoperatively First Eye vs Second Eye, Early Anesthesia vs Standard Anesthesia
- Trial name
- NCT04623229
- Testing
- MCS, ReLACS Early, ReLACS Standard
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Uptown Eye Specialists
Acne, Bites
Implementation of a Minor Ailment Service in Community Pharmacy Practice
Self-care and self-medication are commonly the treatments of choice for the management of minor ailments. Minor ailments can be treated through community pharmacy using a Minor Ailment Service (MAS).
- Conditions
- Acne, Bites, Burns, Cold
- Trial name
- INDICA+PRO (NCT05247333)
- Testing
- Minor ailment service
- Where
- Spain
- Volunteers
- 20,987 people
- Sponsor
- Universidad de Granada
Inflammation and Pain Associated With Cataract Surgery
Study to Evaluate ISV-305 Compared to Vehicle for Treatment of Inflammation and Pain Associated With Cataract Surgery
The purpose of this study is to evaluate the ocular safety, tolerability, and efficacy of ISV-305 (dexamethasone in DuraSite® 2) compared with Vehicle in the treatment of inflammation and pain associated with cataract surgery.
- Trial name
- ISV-305 (NCT03192137)
- Testing
- ISV-305, Vehicle
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Neonatal Pain, Retinopathy of Prematurity (ROP)
Fentanyl Intranasal for Retinopathy of Prematurity Screening in Preterm Infants
The goal of this clinical trial is to learn whether intranasal fentanyl (a pain medicine given as a nasal spray) can reduce pain and is safe to use during routine eye examinations for retinopathy of prematurity (ROP) in preterm…
- Conditions
- Neonatal Pain, Retinopathy of Prematurity (ROP), Pain Management, Infant, Premature
- Trial name
- FIREFLY (NCT07112430)
- Testing
- Fentanyl Citrate (Intranasal)
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- Marsha Campbell-Yeo
Light Sensitivity
"Eye Protection After Mydriatic Use for ROP Screening: Impact on Vitals Signs and Pain Scores"
Pupillary dilation induced by mydriatic agents during Retinopathy of Prematurity exams can persist for hours. Despite regular use of eye protection for mydriatic-induced light sensitivity for infants, children and adults, eye…
- Trial name
- NCT01860534
- Testing
- eye covers
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Cataract
Combined Intracameral Lidocaine for Manual Small Incision Cataract Surgery Under Topical Anesthesia
The purpose of this study is to determine whether intraocular lidocaine increases patient comfort during the different stages of MSICS while under topical anesthesia.
- Trial name
- NCT01023334
- Testing
- MSICS under topical anesthesia with intracameral lidocaine, MSICS under topical anesthesia with intracameral balanced salt solution.
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Wenzhou Medical University
Neck Pain, Unilateral Blindness
Unilateral Blindness/ Unilateral Deafness-relation to Neck Pain
Neck pain is a common complaint in the general population affecting 10-15% of the general population. females more than men. Known risk factors are: Trauma, Repetitive lifting of heavy objects at work, driving vibrating vehicles…
- Conditions
- Neck Pain, Unilateral Blindness, Unilateral Deafness
- Trial name
- NCT00589407
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
Premature Retinopathy, Pain, Eye
Multisensory Stimulation in Infants for Eye Examination
This study aimed to evaluate the effects of multisensory stimulation on pain and physiological parameters resulting from ROP examination in preterm newborns. It was planned as a randomized controlled trial.
- Trial name
- NCT05830409
- Testing
- Multisensorial Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Akdeniz University
TNF-receptor Associated Periodic Syndromes (TRAPS)
Efficacy and Safety Study of ACZ885 in Patients With Active Recurrent or Chronic TNF-receptor Associated Periodic Syndrome (TRAPS).
This trial will assess the safety and efficacy of ACZ885 in patients with active recurrent or chronic TNF-receptor associated periodic syndrome (TRAPS).
- Trial name
- NCT01242813
- Testing
- ACZ885
- Where
- 6 sites in Ireland, Italy and 1 more
- Volunteers
- 20 people
- Sponsor
- Novartis Pharmaceuticals
Retinopathy of Prematurity, Dexmedetomidine
Intranasal Dexmedetomidine for Pain Management During Screening for Retinopathy of Prematurity
Background: Preterm infants undergo serial eye examinations during their hospital stay to monitor for the development of a specific disease termed "retinopathy of prematurity".
- Trial name
- NCT06067958
- Testing
- Dexmedetomidine, Saline
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Retinopathy of Prematurity, Pain
Acupuncture for Preterm Infants Requiring Eye-exam
The purpose is to investigate whether non-invasive acupuncture - NIA (i.e. acupuncture without needles) will help reduce pain for babies in the Neonatal Intensive Care Unit (NICU) during their routine weekly eye-exam for…
- Conditions
- Retinopathy of Prematurity, Pain, Acupuncture, Premature Infant
- Trial name
- MAGNIFIC-ROP (NCT03650621)
- Testing
- Magnetic acupuncture, stickers (magnets removed)
- Where
- 3 sites in Australia, Canada and 1 more
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Premature, Retinopathy of Prematurity
Comfort Level in Premature Infants Undergoing Retinopathy of Prematurity Screening
Retinopathy of prematurity (ROP) screening is a routine yet painful procedure for premature infants, often necessitating pharmacological mydriasis.
- Conditions
- Premature, Retinopathy of Prematurity, Pain
- Trial name
- NCT07016984
- Testing
- standard phototherapy eye patches
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Nisantasi University
Premature Retinopathy, Pain
The Effect of Ocean Sound In Premature Retinopathy Examination
Purpose: It was planned as a randomized controlled experiment in order to evaluate the effectiveness of the ocean sound on pain, comfort and physiological parameters in the NICU, Retinopathy of Prematurity (ROP) examination.
- Trial name
- NCT05203159
- Testing
- Ocean sound, Routine
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Retinopathy of Prematurity
Effect of Benoxinate Hydrochloride Eye Drops on The Premature Infant Pain Profile Score During Retinopathy of Prematurity Screening
Aims: To evaluate the effects of topical Benoxinate HCL eye drops on the Premature Infant Pain Profile (PIPP) scores in infants undergoing Retinopathy of Prematurity (ROP) screening.
- Trial name
- NCT06461975
- Testing
- Benoxinate Hydrochloride, artificial tear (Sodium Hyaluronate 2 mg/ml) eye drops.
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Alexandria University
Erosion; Cornea, Traumatic
Comparison Between Bandage Contact Lens and Pressure Patching for The Erosion Area and Pain Scale in Corneal Erosion Patients
This research aims to compare between bandage contact lens and pressure patching in reducing size of erosion area and pain scale in corneal erosion patients as well as its complications.
- Trial name
- NCT01809483
- Testing
- Bandage contact lens, Pressure patching
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Udayana University