Clinical trials: Pain Acute
Burns, Acute Pain
VR-PAT During Home Burn Dressings - Multisite
This study will evaluate the effectiveness of smartphone Virtual Reality Pain Alleviation Therapy (VR-PAT) as a pain distraction tool during repeated at-home burn dressing changes among 100 children (age 6-17 years) with a burn…
- Conditions
- Burns, Acute Pain, Procedural Pain, Injuries
- Trial name
- NCT05673551
- Testing
- VR-PAT
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Nationwide Children's Hospital
Acute Pain
Pain Relief in the Emergency Department Waiting Room: a Prevalence Study
Pain in the emergency room is under documented and pain relief suboptimal. Data on nurse driven analgesia in emergency department waiting rooms is lacking.
- Trial name
- NCT03115684
- Volunteers
- 2,371 people
- Sponsor
- University Hospital, Geneva
Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis
Buprenorphine for the Management of Pain in Children With Sickle Cell Disease
The goal of this clinical trial is to learn whether a single dose of buccal buprenorphine (BELBUCA) is safe when used in place and/or with full agonist opioids that would otherwise be started during a sickle cell pain crisis…
- Conditions
- Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis, Sickle Cell Anemia Crisis, Sickle Cell Anemia in Children
- Trial name
- NCT07799571
- Testing
- Buprenorphine Buccal Film [Belbuca]
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Natasha Archer
Pain, Acute, Newborns
Effect of Kangaroo Care and Swaddling Methods on Pain Level and Crying Time During Heel Blood Collection
This prospective study is planned as a randomized controlled study with the purpose of determining the effect of kangaroo care and swaddling methods on pain levels and crying times by newborns during heel blood collection.
- Conditions
- Pain, Acute, Newborns, Crying
- Trial name
- NCT06350071
- Testing
- Kangaroo Care, Swaddling
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Arthroplasty, Replacement, Hip
Effects of Photobiomodulation Therapy (PBMT) in Total Hip Arthroplasty
Osteoarthritis (OA), a chronic degenerative muscle disease characterized by cartilage wear, causes progressive joint deformity and loss of function leading to the indication of total hip arthroplasty (THA), when conservative…
- Trial name
- NCT02970890
- Testing
- Portable Pain Away™
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Adriane Aver Vanin
Abdominal Pain, Isolated Extremity Fracture
Morphine or Ketamine for Analgesia
Pain is common in children presenting to the emergency department but is frequently undertreated, leading to both short- and long-term consequences.
- Conditions
- Abdominal Pain, Isolated Extremity Fracture, Pain, Pediatrics
- Trial name
- MoKA (NCT06835504)
- Testing
- Ketamine hydrochloride, Morphine sulphate
- Where
- 8 sites in United States
- Volunteers
- 1,010 people
- Sponsor
- Columbia University
Pain
Sub-dissociative Ketamine for the Management of Acute Pediatric Pain
The proposed trial is a prospective, double blinded, randomized control trial with the primary aim of determining whether a single, sub-dissociative dose of ketamine will decrease the total narcotic requirements of pediatric…
- Trial name
- NCT01951963
- Testing
- Ketamine, Morphine
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- HealthPartners Institute
Headache, Pregnancy Related
Acute Headache Treatment in Pregnancy: Occipital Nerve Block vs PO Acetaminophen With Caffeine
This is an open label randomized controlled trial evaluating response to bupivacaine occipital nerve block compared to Tylenol/Caffeine cocktail in treatment of pregnant patients seeking care of headache.
- Conditions
- Headache, Pregnancy Related, Occipital Nerve Block
- Trial name
- NCT03951649
- Testing
- Occipital Nerve Block
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Post Operative Pain, Acute
Comparing Efficacy of Different Drugs Combinations for Serratus Anterior Block for Thoracotomy
We aim to compare efficacy and efficiency of serratus anterior block with bupivacaine alone to bupivacaine/magnesium and bupivacaine /nalbuphine in postoperative analgesia for thoracotomy surgery.
- Trial name
- NCT05565235
- Testing
- patients will receive intraoperative serratus block with bupivacaine, serratus block with bupivacaine /magnesium, serratus block with bupivacaine with nalbuphine
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Cairo University
Pain, Postoperative, Postoperative Pain, Acute
Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries
This is a double-arm randomized control trial evaluating the impact of preoperative opioid-free analgesia on time to trial of void in ambulatory urogynecologic surgeries.
- Trial name
- NCT06379425
- Testing
- Acetaminophen, Celecoxib, Gabapentin
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Procedural Pain, Acute Pain
Breathing Toy for Pain Relief in Pediatric Venipuncture
This randomized controlled trial evaluated the effectiveness of a realistic breathing toy distraction intervention on procedural pain, physiological parameters, and parental anxiety during venipuncture in children aged 1-3 years…
- Conditions
- Procedural Pain, Acute Pain, Pediatric Pain
- Trial name
- BREATHE (NCT07430514)
- Testing
- Breathing Simulation Plush Toy Distraction During Pediatric Blood Collection
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Koç University
Regional Anesthesia, Postoperative Pain, Acute
Caudal Block and Transversus Abdominis Plane Block in Pediatric Inguinal Hernia Repair
Pediatric inguinal hernia repair (IHR) candidates experiences ordinarily mild to moderate pain, rarely severe pain in the postoperative period.
- Trial name
- NCT05286190
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Sickle Cell Disease
A Phase 1 Study of Continuous Intravenous L-citrulline During Sickle Cell Pain Crisis or Acute Chest Syndrome
Sickle cell disease is a genetic red blood cell disorder characterized by vaso-occlusion from sickling of red blood cells, that can lead to pain or organ complications such as acute chest syndrome.
- Trial name
- NCT02697240
- Testing
- Intravenous citrulline
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Mississippi Medical Center
Pain, Acute, Pain, Procedural
Pain Modality Treatment After Hemorrhoidectomy
Hemorrhoidectomy is one of the operations that causes the greatest intensity of pain. Treatment of postoperative pain is essential for the well-being of the patient.
- Trial name
- NCT04953182
- Testing
- Pain scale registry
- Volunteers
- 5,335 people
- Sponsor
- Assuta Medical Center
IgE-mediated Abdominal Pain
INhaled Salbutamol vs Placebo for the Treatment of Acute IgE-mediated Abdominal Pain From Allergic Food REactions
The goal of this study is to assess the efficacy of inhaled salbutamol to treat abdominal pain during food allergic reactions. Patients experiencing abominal pain as a result of a food allergic reaction during a food challenge in…
- Trial name
- INSPIRE (NCT05653024)
- Testing
- Salbutamol
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Philippe Bégin
Acute Pain
Immune Response of Caudally Administrated Tramadol In Pediatric Lower Abdominal Surgery
Management of acute pain is one of the most important tasks of perioperative pediatric anesthesia. The alleviation of pain has been defined by the Society of Pediatric Anesthesia, on its 15th annual meeting as a basic human…
- Trial name
- NCT02703415
- Testing
- Bupivacaine, Tramadol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Acute Coronary Syndrome, Chest Pain
Database of Patients Undergoing Cardiac Computed Tomographic Angiography at William Beaumont Hospital (CT DATABASE)
The purpose of the study is to establish an overarching database of information containing historical, demographical, clinical, and intermediate and long-term outcome data from all William Beaumont Hospital (WBH) patients…
- Trial name
- CTDATABASE (NCT00922662)
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Kavitha Chinnaiyan
Child Behavior, Pain, Acute
The Effect of Therapeutic Play on Pain, Fear, Anxiety and Physiological Parameters and Parents' Satisfaction
In this study, the effect of the therapeutic game applied before treatment on pain, fear, anxiety and physiological parameters and the satisfaction of the parents was investigated.
- Conditions
- Child Behavior, Pain, Acute, Anxiety and Fear
- Trial name
- NCT06415188
- Testing
- Video game with headset
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Selcuk University
Migraine
A Study of 3 Dosage Strengths of Almotriptan Malate (AXERT®) in the Treatment of Acute Migraine in Adolescents
The purpose of this study is to evaluate the effectiveness and safety of almotriptan malate (AXERT®) in treating acute migraine headaches in adolescents.
- Trial name
- NCT00210483
- Testing
- almotriptan malate
- Volunteers
- 866 people
- Sponsor
- Janssen-Ortho LLC
Acute Abdomen
Laparoscopic Drainage Versus Interventional Radiology In Management Of Appendicular Abscess :
This prospective randomized controlled clinical trial included all patients who developed the manifestations of appendicular abscess and referred to the Zagazig University Hospital Emergency Department between January 2020 and…
- Trial name
- NCT05419440
- Testing
- laparoscopic drainage of appendicular abscess
- Where
- Egypt
- Volunteers
- 172 people
- Sponsor
- Zagazig University