Clinical trials: Pain Control
Scoliosis, Regional Anesthesia
Erector Spine Plane (ESP) Block for Analgesia in Pediatric Scoliosis Surgery
Postoperative pain after scoliosis correction surgery is severe and usually requires long-term intravenous opioid therapy. Local anesthetic options are limited and include intrathecal opioids and epidural analgesia.
- Conditions
- Scoliosis, Regional Anesthesia, Pediatric Anesthesia, Orthopedic Disorder of Spine
- Trial name
- NCT05944393
- Testing
- Ropivacaine 0.2% Injectable Solution, Normal saline 0.9% Injectable Solution
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Poznan University of Medical Sciences
Postoperative Pain, Acute
Effectiveness of Pain Control and Adverse Reactions After Intravenous PCA in Chinese Population
Here, we retrospectively analyzed the proportion of intravenous patient controlled analgesia (PCA) used in a large tertiary hospital in central China, and then further analyzed the proportion of patients with postoperative pain…
- Trial name
- NCT05884021
- Testing
- Postoperative analgesia
- Volunteers
- 40,000 people
- Sponsor
- Huazhong University of Science and Technology
Postoperative Pain
Topical Ketamine Analgesia in Children Undergoing Tonsillectomy: a Clinical and Serum Level Assays Study.
The aim of this study is to evaluate the analgesia efficacy of local ketamine given by two different doses in pediatric patients undergoing tonsillectomy operations
- Trial name
- NCT02720406
- Testing
- Intravenous ketamine0.5mg/kg, Nebulized Ketamine 1mg/kg, Nebulized Ketamine 2mg/kg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Patellofemoral Pain Syndrome
Therapeutic Effect of Two Muscle Strengthening Programs in Patients With Patellofemoral Pain Syndrome
Introduction: The patellofemoral pain syndrome (SPF) is one of the most frequent pathologies generated by the knee joint. Conservative treatment with physiotherapy exercises reduces pain and improves functional capacity in the…
- Trial name
- NCT04011436
- Testing
- Strengthening program
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Multisensory Stimulation
The Effect of Multisensory Stimulus Method on Pain and Physiological Parameters in Infants
This study aimed to investigate the impact of employing the multi-sensory stimulation technique by both the mother and the nurse on the pain and physiological responses of infants aged 2-6 months during vaccination.
- Trial name
- NCT06291519
- Testing
- Multi-sensory Stimulation Method-Mother Applying the Method to the Baby, Multi-sensory Stimulation Method-Nurse Applying the Method to the Baby, Breastfeeding Applied Group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Istanbul University - Cerrahpasa
Epidural Top-up, Labour
Labour Epidural Top-up With Warmed Ropivacaine
The purpose of this study is to determine weather using warmed (body temperature) 0.75% Ropivicaine to convert labour epidural analgesia to surgical anaesthesia, reduces the onset time of surgical block, compared to standard room…
- Conditions
- Epidural Top-up, Labour, Caesarian Section, Ropivacaine
- Trial name
- LETWR (NCT02838329)
- Testing
- warming of ropivacaine for BT, Ropivicaine
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Procedural Sedation and Analgesia
Combined Ketamine/Propofol for Emergency Department Procedural Sedation
Introduction Numerous drugs and combinations of drugs are used for procedural sedation and analgesia (PSA) in Emergency Departments, including propofol, ketamine, benzodiazepines, narcotics, barbiturates, and others, but propofol…
- Trial name
- NCT01126957
- Testing
- Ketamine, Fentanyl, Propofol
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Axillary Brachial Plexus Block
The Efficacy of Intravenous Dexamethasone on the Duration of Analgesia of Ultrasound Guided Axillary Brachial Plexus Block in Pediatric Patients Undergoing Below Elbow Orthopaedic Surgeries
Postoperative pain is a common manifestation in orthopedic patients, mainly due to intraoperative tissue damage , inadequate intraoperative pain assessment and management.
- Trial name
- NCT05466500
- Testing
- Ultrasound guided axillary block with intravenous dexamethasone, Ultrasound guided axillary block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Pain Management, Spinal Fusion
Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal Fusion
This study plans to learn more about preventing pain in children who are having posterior spinal fusion surgery using two different kinds of morphine (a pain medicine).
- Conditions
- Pain Management, Spinal Fusion, Scoliosis
- Trial name
- NCT00880607
- Testing
- Intrathecal morphine, Extended Release Epidural Morphine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Colorado, Denver
Pain, Acute, Fear
The Effect of Puppet Show on Pain and Fear During Subcutaneous Injection in Children With Leukemia
This study aim to evaluate the effect of puppet show applied during subcutaneous injection to children aged 3-7 years with leukemia on the level of pain and fear experienced by children due to the intervention.
- Trial name
- SC-puppet (NCT06013501)
- Testing
- puppet show
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dokuz Eylul University
Pain
Pain Evaluation and Treatment
This study offers evaluation and treatment for patients with a spectrum of acute and chronic pain syndromes. The protocol is not designed to test new treatments; rather, patients will receive current standard of care treatments.
- Trial name
- NCT00362167
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Emergency Service, Hospital, Child/Adolescent Problem
A RCT of a Combination of Analgesics for Pain Management in Children With a Suspected Fracture
MSK-I is the most common cause for ED visits for children with pain, with a child's risk of sustaining a fracture ranging from 27-42% by the age of 16 years.
- Conditions
- Emergency Service, Hospital, Child/Adolescent Problem, Acute Pain, Fentanyl
- Trial name
- CAST (NCT02985177)
- Testing
- INF2.0 + IBU, INF1.0 + IBU
- Where
- 3 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Pain
Does a Perioperative Course of Gabapentin Improve Analgesia After Cesarean Delivery?
Gabapentin has been very effective at treating pain after knee and hip operations, hysterectomies, and many other types of operations.
- Trial name
- NCT01848119
- Testing
- Gabapentin, lactose
- Where
- Canada
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Asepsis, Analgesia, Epidural
Chlorhexidine Versus Povidone-Iodine for Prevention of Epidural Needle Contamination in the Parturient
Infection after epidural catheter placement is fortunately rare. When it does happen, the affected person can become seriously ill.
- Conditions
- Asepsis, Analgesia, Epidural, Anesthesia, Epidural
- Trial name
- NCT00223002
- Testing
- Chlorhexidine
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Caudal Epidural Anesthesia, Sacral Erector Spinae Plane Block
Comparison of Erector Spinae Plane Block and Caudal Block for Postoperative Analgesia in Pediatric Patients Undergoing Orchiopexy: A Prospective Observational Study
This study aims to compare the analgesic efficacy of ultrasound-guided erector spinae plane block and caudal block for postoperative pain management in pediatric patients undergoing orchiopexy.
- Conditions
- Caudal Epidural Anesthesia, Sacral Erector Spinae Plane Block, Orchiopexy, FLACC Scale
- Trial name
- NCT07762339
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Pain, Acute, Child Behavior
The Effect of "Quantum-Touch" on Pain, Fear, and Anxiety of the Children
This research is a randomized controlled experimental study designed to determine the effect of the Quantum-Touch method applied during the vascular access procedure in children aged 7-12 years, on the level of pain, fear and…
- Conditions
- Pain, Acute, Child Behavior, Anxiety and Fear, Venipuncture Site Reaction
- Trial name
- NCT05828264
- Testing
- Quantum touch
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Trakya University
Anxiety, Children
The Effect of Parental Anxiety Level on the Child's Anxiety Level and Postoperative Pain in Children Undergoing Surgery.
The aim of this prospective study is to investigate whether the anxiety levels of parents of children aged 2-6 years who will undergo inguinal area surgery have an effect on the child\'s preoperative anxiety level and…
- Trial name
- NCT06404879
- Testing
- determining scores with tests
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Giresun University
Postoperative Analgesia, Transversus Abdominis Plane (TAP) Block
Transversalis Fascia Plane Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Children
This prospective clinical study aims to compare the postoperative analgesic efficacy of the ultrasound-guided transversalis fascia plane block (TFPB) and the transversus abdominis plane (TAP) block in pediatric patients…
- Conditions
- Postoperative Analgesia, Transversus Abdominis Plane (TAP) Block, Transversalis Fascia Plane Block, Pediatric Surgical Procedures
- Trial name
- NCT07242196
- Testing
- Postoperative analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Dental Procedures
Virtual Reality vs. Standard-of-Care for Comfort During Dental Procedures in Children
Children sometimes need dental procedures which can be painful and associated with child pain and anxiety. In addition to pain medication, distraction may help children cope with the pain.
- Trial name
- NCT03862573
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of British Columbia
Post-operative Pain
Post-operative Oral Morphine Versus Ibuprofen
Children 5-17 years of age who have undergo orthopedic day surgical procedures for definitive management of fractures, tendon release, etc.
- Trial name
- NCT01686802
- Testing
- oral morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
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