Clinical trials: Pain Intensity
Multiple Sclerosis, Peripheral Neuropathy
Effects of Meditation on Multiple Sclerosis and Peripheral Neuropathy
This study will evaluate the effects of mindfulness and concentration meditation on pain, fatigue, and physical functioning in patients with either multiple sclerosis or peripheral neuropathy.
- Trial name
- NCT00981643
- Testing
- Meditation instruction and practice
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cleveland Clinic
Tonsillectomy, Adenoidectomy
Preoperative VR Cartoon Viewing Reduces Postoperative Pain and Anxiety in Pediatric Tonsillectomy Patient
The aim of this study is to determine the effect of watching a cartoon with a virtual reality headset before surgery on the pain and anxiety levels of children aged 7-12 years.
- Trial name
- NCT06763276
- Testing
- Virtual Reality Group
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Izmir Tinaztepe University
Appendicitis Surgery, Inguinal Surgery
The Effect of TENS Application for Pain
The aim of the study which was planned in a randomized controlled experimental design, it was aimed to determine the effect of Transcutaneous Electrical Nerve Stimulation (TENS) application on pain level before mobilization in…
- Trial name
- NCT05119621
- Testing
- TENS application
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- KTO Karatay University
Patellofemoral Pain Syndrome, Patellofemoral Pain
Neural Correlates of Knee Sensorimotor Control in Patients With Patellofemoral Pain Syndrome
This study aims to determine the neural correlates of knee motor control in young females with patellofemoral pain (PFP). Each participant will attend a single study visit which may last up to 3 hours.
- Trial name
- NCT04099004
- Testing
- Neural Imaging
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Emory University
Primary Dysmenorrhea
Efficacy and Safety of DEH113 in the Treatment of Menstrual Cramp Pain in Primary Dysmenorrhea: a Pilot Study
This study aims to evaluate the preliminary efficacy and safety of DEH113 in the Treatment of Menstrual Cramps Pain Associated with Primary Dysmenorrhea.
- Trial name
- NCT06555549
- Testing
- DEH113
- Volunteers
- 60 people
- Sponsor
- EMS
Pain, Postoperative, Phimosis
Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Circumcision is the most common surgical procedure performed by Pediatric Urologists. Ketorolac has been shown to have an efficacy similar to morphine in multi-modal analgesic regimens without the commonly associated adverse…
- Conditions
- Pain, Postoperative, Phimosis, Paraphimosis, Balanitis
- Trial name
- NCT02973958
- Testing
- Bupivacaine, Sevoflurane, Acetaminophen
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Dental Pain
Buffered Local Anesthetic
The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of…
- Trial name
- NCT05757648
- Testing
- Non-buffered Anesthetic, Buffered Anesthetic, Onset
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Chronic Pain Syndrome
Post-reimbursement Study to Follow Spinal Neurostimulator Devices for Pain Therapy (French SCS Registry)
Observational study to evaluate the long term efficacy of Spinal Cord Stimulation (SCS) over 2 years following SCS implant. This study is requested by French Health Authorities for reimbursement renewal, to maintain reimbursement…
- Trial name
- SME (NCT01778426)
- Where
- France
- Volunteers
- 414 people
- Sponsor
- MedtronicNeuro
Functional Gastrointestinal Disorders
Study of Medication for Functional Abdominal Pain in Children
The purpose of this study is to determine where amitriptyline is effective in the treatment of functional abdominal pain in children.
- Trial name
- NCT00564525
- Testing
- Amitriptyline
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Pain Management
Evaluation of Paro, a Therapeutic Assistance Robot in Analgesic Management During the Placement of a Peripheral Intravenous Line in Infants and Children.
Peripheral intravenous catheterization is one of the most frequently performed procedures in pediatric emergency departments and hospital units.
- Trial name
- PARO (NCT07299006)
- Testing
- Experimental group: Standard multimodal pain management strategy supplemented with the PARO therapeutic robot., Non-pharmacological and standard pharmacological interventions.
- Where
- 5 sites in France
- Volunteers
- 120 people
- Sponsor
- Fondation Lenval
Tonsillectomy
Suprazygomatic Nerve Block in Tonsillectomy Patients
The use of suprazygomatic maxillary nerve block to reduce postoperative pain and hospital stay is greater than the use of NSAID and opioids.
- Trial name
- NCT06359925
- Testing
- Suprazygomatic maxillary nerve block using dexmedetomidne and Bupivacaine, Suprazygomatic maxillary nerve block using Bupivacaine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cleft Lip Palate, Orofacial Cleft
Effect of Opioid-Free vs Opioid-Based Anesthesia on Postoperative Pain and Emergence Agitation in Children Undergoing Cleft Surgery
Orofacial clefts are among the most common congenital malformations, affecting approximately 1 in 700-1500 live births worldwide.
- Conditions
- Cleft Lip Palate, Orofacial Cleft, Agitation, Emergence, Analgesia Assessment
- Trial name
- NCT07557576
- Testing
- Ketamine (1 mg/kg), Dexmedetomidine (1-0,8-0,6-0,4 mcg/kg/h), Fentanyl 5 mcg/kg
- Where
- Croatia
- Volunteers
- 90 people
- Sponsor
- Iva Smiljanić
Procedural Pain, Procedural Anxiety
Efficacy of VR and Buzzy on Pain and Anxiety
The study was designed as a randomized controlled experimental research with the purpose of determining the effect of distraction by using external cold and vibration-Buzzy and VR on reducing procedural pain and anxiety in…
- Conditions
- Procedural Pain, Procedural Anxiety, Pain, Children, Only
- Trial name
- NCT05179291
- Testing
- Buzzy Group, Virtual Realitiy-VR Group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Pain
Self-administered Intravaginal 2% Lidocaine Gel Prior to Intrauterine Device Insertion in Nulliparous Women
This study is designed to evaluate if self-inserted intravaginal 2% lidocaine gel is effective at decreasing pain during intrauterine device insertion in nulliparous women.
- Trial name
- LIVIIN (NCT01534520)
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Spinal Cord Injuries, Neuropathic Pain
Evaluation of Initiation Time on the Efficacy of Gabapentin in Treating Neuropathic Pain in SCI
Neuropathic pain is a common complaint in those with spinal cord injury (SCI) that has a significant negative effect on quality of life. Efficacy of various treatments, however, remains controversial.
- Trial name
- NCT04256603
- Testing
- Gabapentin, No gabapentin
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- MetroHealth Medical Center
Persistent Ductus Arteriosus, Complication of Prematurity
The Preterm Infants' Paracetamol Study
Present randomized, controlled, double-blind trial investigates the efficacy and safety of early (<24 h) intravenous paracetamol therapy for pain medication in very small premature infants.
- Conditions
- Persistent Ductus Arteriosus, Complication of Prematurity, Pain or Discomfort in Intensive Care of Preterm Infants
- Trial name
- PreParaS (NCT01938261)
- Testing
- paracetamol, 0.45 % saline solution
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- University of Oulu
Local Anesthetic Efficacy
Effectiveness of Nitrous Oxide 50% for Reducing Pain and Distress Associated with Needle-stick in Children
Venipuncture (puncturing of a vein) through the skin in order to insert a vein catheter (also know as cannula) is one of the most common needle-related medical procedures performed in children.
- Trial name
- NCT03342079
- Testing
- Local Anesthetics,(lidocaine 70 mg/tetracaine 70 mg topical patch; Synera)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Opioid Use, Acute Pain
Appropriate Opioid Quantities for Acute Pain - Pharmacist Study
Prescription opioids contribute to opioid related deaths, overdose and addiction. Unused prescribed opioids are not routinely being stored or disposed of appropriately and their availability is associated with harms.
- Trial name
- NCT04484610
- Testing
- Pharmacist Practice Change to Dispense Appropriate Opioid Quantities for Acute Pain
- Where
- Canada
- Volunteers
- 205 people
- Sponsor
- Centre for Addiction and Mental Health
Dental Anxiety, Pain
Effectiveness of Hand/Eyes/Mouth Behavior Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this studio will be to evaluate the effectiveness of "Hands/Eyes/mouth" behavior management technique versus a conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02591797
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Cardenal Herrera University
Pain
Effect of the DentalVibe Injection System on Pain During Local Anesthesia Injections in Children
Title: Effect of the DentalVibe injection system on pain during local anesthesia injections in children. Purpose: The purpose of this study is to compare self-reported pain scale measurements using the Wong-Baker FACES pain…
- Trial name
- NCT03374982
- Testing
- DentalVibe
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Nebraska
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