Clinical trials: Pain-Knee
Pain, Postoperative, Anterior Cruciate Ligament Injuries
IPACK on Early Pain Scores After ACL Reconstruction
The goal of this clinical trial is to learn whether using an anesthetic technique called IPACK block will control pain after ACL reconstruction surgery.
- Conditions
- Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid
- Trial name
- NCT05985629
- Testing
- IPACK
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Loyola University
Chronic Ankle Instability
Relationship of Dynamic Knee Valgus With Foot Posture, Pain, and Balance in Chronic Ankle Instability.
The purpose of the study is to identify if there is a relationship between the frontal plane projection angle as a measure of dynamic knee valgus with foot posture, pain, and dynamic balance in chronic ankle instability patients.
- Trial name
- DKV/CAI (NCT07121725)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament Rupture
Intra-articular Administration of 3.0g Tranexamic Acid Has no Effect on Reducing Intra-articular Hemarthrosis and Postoperative Pain After Primary Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial
The purpose of this study was to investigate whether intraarticular administration of tranexamic acid could reduce hemarthrosis and postoperative pain in patients following anterior cruciate ligament reconstruction.
- Trial name
- NCT04042688
- Testing
- intraarticular administration of tranexamic acid
- Where
- South Korea
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Osteoarthritis, Knee
Comparison of Heated vs. Pulsed Radiofrequency Treatment of the Genicular Nerves for Osteoarthritis Knee Pain
This is a prospective, randomised, interventional, double blinded study to compare the clinical outcomes of thermal vs. pulsed radiofrequency (RF) treatment of the genicular nerves in patients with painful osteoarthritis (OA) of…
- Trial name
- NCT04379895
- Testing
- Radiofrequency ablation
- Volunteers
- 60 people
- Sponsor
- Rambam Health Care Campus
Patellar Denervation, Non-patellar Denervation
Comparative Study Between Patellar Denervation and Non-patellar Denervation in Total Knee Arthroplasty With Patellar Resurfacing
The purpose of this study is to compare the post-operative anterior knee pain (AKP) between patellar denervation and non-patellar denervation in total knee arthroplasty with patellar resurfacing
- Conditions
- Patellar Denervation, Non-patellar Denervation, Patellar Resurfacing
- Trial name
- NCT03389880
- Testing
- Total knee arthroplasty, Patellar denervation
- Where
- Thailand
- Volunteers
- 241 people
- Sponsor
- Navamindradhiraj University
Osteoarthritis, Knee
Standard Versus Novel RFA for Chronic Knee Pain in Osteoarthritis
Brief Summary The goal of this pilot study is to evaluate the feasibility and safety of conducting a randomized comparison of two standard-of-care knee radiofrequency ablation (RFA) techniques in adults with chronic knee pain…
- Trial name
- NCT07674082
- Testing
- Radiofrequency ablation - 3-target technique, Radiofrequency ablation - 6-target technique
- Volunteers
- 24 people
- Sponsor
- Lawson Research Institute of St. Joseph's
Burns, Knee Injuries
Opioid Laws and Pediatric Use
The legitimate need for opioid medications for acute pain management in pediatric trauma patients is recognized, however, the high dose and duration of opioid drugs prescribed by medical providers has been associated with an…
- Conditions
- Burns, Knee Injuries, Opioid Use, Pain
- Trial name
- NCT04543227
- Testing
- Opioid Use 90-Days Post Treatment
- Where
- United States
- Volunteers
- 980 people
- Sponsor
- Nationwide Children's Hospital
Knee Disease, Nerve Pain
Triple Injection Peri-sartorius (TIPS) Block
Comparison between the pain scores after total knee arthroplasty in patients receiving triple injection peri-sartorius (TIPS) block versus femoral nerve block (FNB)
- Trial name
- NCT05289427
- Testing
- ultrasound guided triple injection peri-sartorius block, Femoral Nerve Block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Arthroplasty, Replacement, Knee
Intraarticular Analgesia After Total Knee Arthroplasty, a Randomised Study
The study aims to compare two different kinds of pain treatment after total knee replacement (operation with artificial knee joint): 1) a large local injection in and around the knee, supplemented with injection the day after, or…
- Trial name
- NCT00269529
- Testing
- femoral nerve block, knee infiltration and injection via catheter
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Traumatic Articular Cartilage Defects in the Knee Joint
Phase III Study to Evaluate Safety and Effectiveness of NOVOCART 3D Plus vs. Microfracture in Knee Cartilage Defects
In this phase 3 clinical trial, a second generation ACI (autologous chondrocyte implantation technique) is compared to standard of care therapy (microfracture) to treat traumatic cartilage defects of the knee for efficacy and…
- Trial name
- N3D (NCT01656902)
- Testing
- NOVOCART® 3D plus, Microfracture
- Where
- 35 sites in Austria, Czechia and 8 more
- Volunteers
- 263 people
- Sponsor
- Tetec AG
Pain, Postoperative
Efficiency Study About the Effect of Acupuncture on Postoperative Pain After Total Knee Arthroplasty
The purpose of this study is to evaluate the use of needle acupuncture in comparison to a conventional postoperative pain management in terms of reducing pain and pain medication use in an interdisciplinary setting in a…
- Trial name
- APOPKA (NCT02456116)
- Testing
- acupuncture/PCA/NSAID, PCA/NSAID
- Where
- Austria
- Volunteers
- 90 people
- Sponsor
- Medical University of Vienna
Knee Pain
A Reliability and Validity Study of Urdu Version of Knee Outcome Survey-Activities of Daily Living Scale
The purpose of this study is to translate Knee Outcome Survey-Activities of Daily Living Scale into Urdu language and to check the reliability and validity of the Knee Outcome Survey-Activities of Daily Living Scale in Urdu…
- Trial name
- NCT05221047
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Riphah International University
Postoperative Pain, Analgesia
Evaluation of Dexketoprofen in Total Knee Arthroplasty
Pain is a global public health issue and represents the most common reason for both physician consultation and hospital admissions. Dexketoprofen is a new NSAID treating acute postoperative pain.
- Trial name
- NCT04161690
- Testing
- Dexketoprofen Trometamol, Ropivacaine Hydrochloride 7.5 MG/ML
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- KAT General Hospital
Osteoarthritis of the Knee
Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
The purpose of this study is to test whether surgical insertion of total knee replacement provides further improvement in quality of life, pain and function in addition to an algorithm for systematic non-surgical treatment…
- Trial name
- MEDIC (NCT01410409)
- Testing
- Neuromuscular training (NEMEX-TJR), Paracetamol, Burana
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Clinical Comparison of Patellofemoral Pain Syndrome Outcomes After Blood Flow Restriction Therapy
The purpose of this study is to determine if Blood Flow Restriction therapy improves patient related outcomes in those diagnosed with Patellofemoral Pain Syndrome compared to those in the sham comparator control group.
- Trial name
- NCT05617911
- Testing
- Blood Flow Restriction Cuff
- Where
- 6 sites in United States
- Volunteers
- 1 people
- Sponsor
- Gaylord Hospital, Inc
Pain, Spinal Surgeries, Hip and Knee Joint Replacement, Adverse Events
RAHM Foundation Retrospective Study of Various Diseases
This is a retrospective data collection on treatment of various disorders. This registry will include a variety of different products, implants, technologies and procedures.
- Trial name
- NCT02359786
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Rahm Foundation
Osgood-Schlatter Disease, Sever's Disease
Individualized Rehabilitation for Osgood-Schlatter or Sever Pain in Youth Athletes
The goal of this clinical trial is to learn if a 12-week individualized rehabilitation program is feasible and helpful for children and adolescents with lower-extremity apophyseal pain, including Osgood-Schlatter-related knee…
- Conditions
- Osgood-Schlatter Disease, Sever's Disease, Apophyseal Pain, Sinding-Larson and Johansson Syndrome (SLJ)
- Trial name
- LEAP-REHAB (NCT07521280)
- Testing
- Individualized Load-Based Rehabilitation Pathway
- Where
- Poland
- Volunteers
- 45 people
- Sponsor
- Medical University of Gdansk
ACL Tear, Post Operative Pain
Impact of Opioid Avoidance Protocol for ACL Reconstruction
This is a prospective, quasi-experimental, cohort study comparing patients treated with one of two postoperative pain management protocols.
- Trial name
- NCT06340932
- Testing
- Iovera, Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Matthew Varacallo
Knee Osteoarthritis, Pain, Chronic
Association of Acupuncture and Cupping in Advanced Knee Osteoarthritis
Given the lack of studies in the literature associating the use of acupuncture and sliding suction cup in patients with advanced knee osteoarthritis, the objective of this study is to evaluate the benefits of this association in…
- Trial name
- NCT04168593
- Testing
- Acupuncture
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo General Hospital
Postoperative Pain
Auricular Acupuncture for Pain Relief After Ambulatory Knee Arthroscopy
The aim was to investigate whether auricular acupuncture is superior to sham acupuncture in relief of acute postoperative pain and in reduction of analgesics consumption on demand and their side effects in patients after…
- Trial name
- NCT00233857
- Testing
- Auricular acupuncture
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University Medicine Greifswald