Clinical trials: Palliative Cancer
Multidisciplinary Collaborative, Palliative Care Model
The Clinical Effect of Palliative Treatment on Patients With Terminal Cancer
This study proposed a multidisciplinary collaborative team combined with a palliative care model and proposed to establish a team composed of medical staff in various disciplines to make up for the defects of a conventional…
- Conditions
- Multidisciplinary Collaborative, Palliative Care Model, Quality of Life
- Trial name
- NCT05683236
- Testing
- Health education, Comfort care, Pain care
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shijiazhuang People's Hospital
End of Life, Communication
Informational Meetings for Planning and Coordinating Treatment
This prospective cluster-randomized trial examines the efficacy of a novel communication intervention delivered by trained physician and nurse dyads to parents of children with cancer within the clinicians' practice, to foster…
- Conditions
- End of Life, Communication, Cancer Metastatic
- Trial name
- IMPACT (NCT04330833)
- Testing
- Novel Communication Intervention, Enhanced Usual Care Parent Education
- Where
- 7 sites in United States
- Volunteers
- 111 people
- Sponsor
- Indiana University
Pediatric Malignant Brain Tumor -Diffuse Intrinsic Pontine Glioma
Palliative Re-irradiation for Progressive Diffuse Intrinsic Pontine Glioma (DIPG) in Children
Although DIPG is not curable, re-irradiation with a modest total dose and short treatment time provides good palliation of symptoms, improves quality of life, delays disease progression and has minimal and manageable toxicity.
- Trial name
- NCT01777633
- Testing
- Palliative re-irradiation for progressive DIPG in children
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Hadassah Medical Organization
Terminal Cancer
Towards Cancer Patient Empowerment for Optimal Use of Antithrombotic Therapy at the End of Life
Despite the fact that antithrombotic therapy (ATT) has little or even negative effects on the well-being of cancer patients during their last year of life, stopping ATT is rare in clinical practice.
- Trial name
- SERENITY (NCT05706740)
- Testing
- Physician survey on antithrombotic medication during end-of-life care in cancer patients
- Where
- 12 sites in Denmark, France and 6 more
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Chronic Lymphocytic Leukemia, Myelodysplastic Syndromes
MyPal ePRO-based Early Palliative Care System in Adult Patients With Hematologic Malignancies
Randomized unblinded interventional clinical trial: Arm Intervention Experimental arm (n=150): Intervention group Administration of the MyPal ePRO system the intervention group will use the ePRO tools provided in the project.
- Trial name
- NCT04370457
- Testing
- Administration of the MyPal ePRO system
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Centre for Research and Technology Hellas
Pediatric Cancer
Nurse-led Transitional Care to Improve Symptom Management in Childhood Cancer Survivors
This study aims to evaluate the feasibility and preliminary effectiveness of a nurse-facilitated interdisciplinary transitional care programme, based on the Omaha system, for Chinese childhood cancer survivors (CCSs) and their…
- Trial name
- NCT07273682
- Testing
- Counseling based on Omaha system, Usual Care
- Volunteers
- 68 people
- Sponsor
- The Hong Kong Polytechnic University
Palliative Care, Acute Myeloid Leukaemia
Effectiveness of Early Intervention in Palliative Care for Acute Myeloid Leukemia Patients Comparing to Standard of Care
Hemato-oncology patients undergoing intensive chemotherapy treatments experience different types of symptoms during and after treatments, which are often refractory to the established therapy.
- Trial name
- NCT06848270
- Testing
- Early palliative care integration
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Universidade do Porto
Pediatric Neoplasm, Quality of Life
The PediQUEST Study: Evaluation of Pediatric Quality of Life and Evaluation of Symptoms Technology
Over 50% of children dying from cancer still suffer from symptoms that could be effectively alleviated. The purpose of the Pediatric Quality of Life and Evaluation of Symptoms Technology (PediQUEST) Study was to evaluate whether…
- Conditions
- Pediatric Neoplasm, Quality of Life, Outcome Assessment, Palliative Care
- Trial name
- NCT01838564
- Testing
- Routine Data collection, Feedback of patient-reported outcomes
- Where
- 4 sites in United States
- Volunteers
- 104 people
- Sponsor
- Dana-Farber Cancer Institute
Cancer, Congenital Anomalies
Estimating the Global Need for Palliative Care for Children
A cross-sectional analysis of prevalence data from a stratified sample of 23 countries used to estimate the global need for palliative care for children aged 0-19 years.
- Conditions
- Cancer, Congenital Anomalies, Cardiovascular Disease, HIV
- Trial name
- NCT02553148
- Testing
- Need for children's palliative care
- Where
- United States
- Volunteers
- 18,837,613 people, healthy volunteers welcome
- Sponsor
- International Children's Palliative Care Network
Paediatric Oncology Palliative Care
Developing a Symptom List for Children With Cancer
Primary Objective The aim of this research study is to develop a comprehensive inventory of symptoms that occur in children with advanced cancer who are receiving a specialist palliative care service.
- Trial name
- NCT02726815
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Cancer, Heart Failure
Virtual Reality as an Adjunct to Management of Pain and Anxiety in Palliative Care
Virtual reality has been shown to be an effective way to treat pain and anxiety in various different settings. Palliative care is an area of medicine that often deals with patients suffering from pain and anxiety.
- Conditions
- Cancer, Heart Failure, Copd, ALS
- Trial name
- NCT04138095
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Riverview Health Centre
Brain Tumor, Pediatric, Brainstem Glioma, Brain Tumor, Pediatric, Recurrent
Application of Palliative Treatment in Children With Brain Stem Glioma and Recurrent High-grade Tumors in the Central Nervous System With the Nanomaterial NPt-Ca
This Protocol is a pilot, clinical interventional study to selected patients between five and fourteen years of both sexes, carriers of the diagnosis of glioma brain stem and high grade recurrent in the central nervous system…
- Trial name
- NCT03250520
- Testing
- Platinum acetylacetonate (1% wt) supported by sol-gel technology functionalized titania
- Where
- Mexico
- Volunteers
- 8 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Adolescent and Young Adult Cancer Patient
Adolescents and Young Adults (AYAs) With Advanced Cancer
This study aims to develop and test the feasibility and acceptability of a psychosocial symptom management intervention designed to meet the unique needs of Adolescents and Young Adults (AYAs) with advanced cancer.
- Trial name
- NCT05593016
- Testing
- Symptom Management for Improved Physical and Emotional Wellbeing (SMILE), Education Control Arm
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Duke University
Terminal Cancer, Hospice
Exploring Indications and Practices of Administering Artificial Hydration to Terminal Cancer Patients in Taiwan
Background: The issue of artificial hydration for terminal cancer patients is a classic ethical dilemma in palliative care. It is a common practice especially when patients are incapable of oral intake; however, there is a lack…
- Conditions
- Terminal Cancer, Hospice, Palliative Medicine
- Trial name
- NCT06329856
- Testing
- Administering of artificial hydration
- Where
- Taiwan
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Metastases, Metastatic Cancer
Trial Comparing LATTICE Radiotherapy vs Moderately Dose-escalated Palliative Radiation for Patients With Metastases.
Unblinded, randomized study of 5-fraction LATTICE radiotherapy (20 Gy with an SIB to 66.7 Gy in 5 fractions) versus moderately dose-escalated palliative radiation (25 Gy in 5 fractions)
- Trial name
- NCT07594431
- Testing
- LATTICE Radiotherapy, Standard radiotherapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stanford University
Oral Cancer, Palliative Supportive Care
Early Palliative Care For Patients With Oral Cancer in Sri Lanka
The goal of this quasi experimental study is to develop and assess the effectiveness of an early palliative care intervention in patients with oral cancer in Sri Lanka.
- Conditions
- Oral Cancer, Palliative Supportive Care, Psychological Distress, Quality of Life of Patients
- Trial name
- NCT06726317
- Testing
- Early palliative care integration
- Where
- 4 sites in Sri Lanka
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Colombo
Neoplasms
A Phase I Study of Weekly Gemcitabine in Combination With Infusional Fluorodeoxyuridine and Oral Calcium Leucovorin in Adult Cancer Patients
The purpose of this study is to determine the clinical toxicities associated with administering sequential dFdC as a one hour infusion followed by a continuous infusion of FUdR over 24 hours with low dose oral LV weekly for three…
- Trial name
- NCT00001449
- Testing
- gemcitabine, fluorodeoxyuridine, leucovorin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute (NCI)
Cancer, Congenital Heart Disease
Supporting Patient Provider Communication in Paediatric Care
Children with Cancer or congenital heart disease (CHD) experience complex, physical, psychosocial and behavioural symptoms and problems due to the illness, treatment, and medical procedures.
- Trial name
- SiSom (NCT01280227)
- Testing
- SiSom
- Where
- Norway
- Volunteers
- 144 people
- Sponsor
- Oslo University Hospital
Constipation, Neoplasms
Constipation in Pediatric Cancer Patients Receiving Vinca Alkaloids or Narcotics
This study will evaluate a questionnaire for measuring constipation in children with cancer. The questionnaire used in this study (Constipation Assessment Scale) reliably predicts the presence and severity of constipation in…
- Trial name
- NCT00032682
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Advanced Cancer
Yoga for Adolescent and Young Adult Non-Curative Cancer Patients
Adolescents and young adults who are living with cancer are not benefiting from the same age-appropriate physical and psychosocial care, as are children and older adults.
- Trial name
- NCT01901237
- Testing
- Hatha Yoga
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Rob Rutledge