Clinical trials: Palliative Patients
Multidisciplinary Collaborative, Palliative Care Model
The Clinical Effect of Palliative Treatment on Patients With Terminal Cancer
This study proposed a multidisciplinary collaborative team combined with a palliative care model and proposed to establish a team composed of medical staff in various disciplines to make up for the defects of a conventional…
- Conditions
- Multidisciplinary Collaborative, Palliative Care Model, Quality of Life
- Trial name
- NCT05683236
- Testing
- Health education, Comfort care, Pain care
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shijiazhuang People's Hospital
Terminal Cancer
Towards Cancer Patient Empowerment for Optimal Use of Antithrombotic Therapy at the End of Life
Despite the fact that antithrombotic therapy (ATT) has little or even negative effects on the well-being of cancer patients during their last year of life, stopping ATT is rare in clinical practice.
- Trial name
- SERENITY (NCT05706740)
- Testing
- Physician survey on antithrombotic medication during end-of-life care in cancer patients
- Where
- 12 sites in Denmark, France and 6 more
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Terminal Illness
Is Acupuncture Able to Reduce Nausea and Vomiting in the Terminal Ill Patient
A comparative effectiveness research design was used. The sample size was calculated to 136 patients, who were randomized to an intervention group and a control group respectively.
- Trial name
- NCT04378998
- Testing
- Acupuncture
- Volunteers
- 136 people
- Sponsor
- University of Aarhus
Chronic Lymphocytic Leukemia, Myelodysplastic Syndromes
MyPal ePRO-based Early Palliative Care System in Adult Patients With Hematologic Malignancies
Randomized unblinded interventional clinical trial: Arm Intervention Experimental arm (n=150): Intervention group Administration of the MyPal ePRO system the intervention group will use the ePRO tools provided in the project.
- Trial name
- NCT04370457
- Testing
- Administration of the MyPal ePRO system
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Centre for Research and Technology Hellas
Fontan Procedure, Hypoplastic Left Heart Syndrome
Impact of Vitamin C on Endothelial Function and Exercise Capacity in Fontan-Palliated Patients
In this study, investigators will evaluate the effect of vitamin C on endothelial function, exercise tolerance and quality of life in patients with a single ventricle who have been palliated to Fontan physiology.
- Conditions
- Fontan Procedure, Hypoplastic Left Heart Syndrome, Tricuspid Atresia
- Trial name
- NCT00974025
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Palliative Care
Music Therapy for Palliative Care Patients
This study aims to find out if music therapy is effective in improving the quality of life of palliative care patients. It will do this by comparing palliative care patients who receive music therapy with those who do not receive…
- Trial name
- NCT02791048
- Testing
- Music therapy
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- Queen's University, Belfast
Palliative Care, Acute Myeloid Leukaemia
Effectiveness of Early Intervention in Palliative Care for Acute Myeloid Leukemia Patients Comparing to Standard of Care
Hemato-oncology patients undergoing intensive chemotherapy treatments experience different types of symptoms during and after treatments, which are often refractory to the established therapy.
- Trial name
- NCT06848270
- Testing
- Early palliative care integration
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Universidade do Porto
Pediatric Neoplasm, Quality of Life
The PediQUEST Study: Evaluation of Pediatric Quality of Life and Evaluation of Symptoms Technology
Over 50% of children dying from cancer still suffer from symptoms that could be effectively alleviated. The purpose of the Pediatric Quality of Life and Evaluation of Symptoms Technology (PediQUEST) Study was to evaluate whether…
- Conditions
- Pediatric Neoplasm, Quality of Life, Outcome Assessment, Palliative Care
- Trial name
- NCT01838564
- Testing
- Routine Data collection, Feedback of patient-reported outcomes
- Where
- 4 sites in United States
- Volunteers
- 104 people
- Sponsor
- Dana-Farber Cancer Institute
Nutrition Disorders, Gastrostomy
A Retrospective Analysis of Percutaneous Endoscopic Gastrostomy Experiences
The application of PEG in geriatric-palliative care has not been well discussed. With the development of endoscopic procedures and PEG devices, we can perform this minimally invasive method more safely, even in challenging cases.
- Trial name
- NCT05075616
- Testing
- Percutaneous endoscopic gastrostomy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Okan University
Palliative Medicine
A Multidimensional Strategy to Improve Quality of Life of Patients With Multiple Symptoms and Palliative Care Needs
A nationwide, cross-sectional study, to determine the prevalence of symptoms of patients in the palliative phase in various care settings will be performed within a set period of two weeks in September 2018 and two weeks in…
- Trial name
- MuSt-PC (NCT03665168)
- Where
- Netherlands
- Volunteers
- 659 people
- Sponsor
- University Medical Center Groningen
Pulmonary Atresia With Ventricular Septal Defect, Tetralogy of Fallot With Pulmonary Atresia
Choice of Palliative Procedures for Pulmonary Atresia With Ventricular Septal Defect Patients
The aim is to compare effective growth true hypoplastic pulmonary arteries using Right Ventricle Outflow Tract Reconstruction by femoral allogenic vein valve conduit and systemic-to-pulmonary artery shunts (modified…
- Trial name
- NCT02861963
- Testing
- Experimental: RVOT reconstruction by femoral allogenic vein valve conduit, Systemic-to-pulmonary artery shunts
- Where
- Russia
- Volunteers
- 24 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Heart Defects, Congenital
Long Term Safety of Clopidogrel in Neonates/Infants With Systemic to Pulmonary Artery Shunt Palliation
This study is the extension of the CLARINET study [NCT00396877 -EFC5314] in neonates or infants with cyanotic congenital heart disease palliated with a systemic-to-pulmonary artery shunt.
- Trial name
- CLARINET LT (NCT00833703)
- Testing
- Clopidogrel
- Where
- 15 sites in United States, Brazil and 13 more
- Volunteers
- 49 people
- Sponsor
- Sanofi
Adolescent and Young Adult Cancer Patient
Adolescents and Young Adults (AYAs) With Advanced Cancer
This study aims to develop and test the feasibility and acceptability of a psychosocial symptom management intervention designed to meet the unique needs of Adolescents and Young Adults (AYAs) with advanced cancer.
- Trial name
- NCT05593016
- Testing
- Symptom Management for Improved Physical and Emotional Wellbeing (SMILE), Education Control Arm
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Duke University
Terminal Cancer, Hospice
Exploring Indications and Practices of Administering Artificial Hydration to Terminal Cancer Patients in Taiwan
Background: The issue of artificial hydration for terminal cancer patients is a classic ethical dilemma in palliative care. It is a common practice especially when patients are incapable of oral intake; however, there is a lack…
- Conditions
- Terminal Cancer, Hospice, Palliative Medicine
- Trial name
- NCT06329856
- Testing
- Administering of artificial hydration
- Where
- Taiwan
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Metastases, Metastatic Cancer
Trial Comparing LATTICE Radiotherapy vs Moderately Dose-escalated Palliative Radiation for Patients With Metastases.
Unblinded, randomized study of 5-fraction LATTICE radiotherapy (20 Gy with an SIB to 66.7 Gy in 5 fractions) versus moderately dose-escalated palliative radiation (25 Gy in 5 fractions)
- Trial name
- NCT07594431
- Testing
- LATTICE Radiotherapy, Standard radiotherapy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stanford University
Oral Cancer, Palliative Supportive Care
Early Palliative Care For Patients With Oral Cancer in Sri Lanka
The goal of this quasi experimental study is to develop and assess the effectiveness of an early palliative care intervention in patients with oral cancer in Sri Lanka.
- Conditions
- Oral Cancer, Palliative Supportive Care, Psychological Distress, Quality of Life of Patients
- Trial name
- NCT06726317
- Testing
- Early palliative care integration
- Where
- 4 sites in Sri Lanka
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Colombo
Neoplasms
A Phase I Study of Weekly Gemcitabine in Combination With Infusional Fluorodeoxyuridine and Oral Calcium Leucovorin in Adult Cancer Patients
The purpose of this study is to determine the clinical toxicities associated with administering sequential dFdC as a one hour infusion followed by a continuous infusion of FUdR over 24 hours with low dose oral LV weekly for three…
- Trial name
- NCT00001449
- Testing
- gemcitabine, fluorodeoxyuridine, leucovorin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute (NCI)
Cancer, Congenital Heart Disease
Supporting Patient Provider Communication in Paediatric Care
Children with Cancer or congenital heart disease (CHD) experience complex, physical, psychosocial and behavioural symptoms and problems due to the illness, treatment, and medical procedures.
- Trial name
- SiSom (NCT01280227)
- Testing
- SiSom
- Where
- Norway
- Volunteers
- 144 people
- Sponsor
- Oslo University Hospital
Stroke
Turkish Validity and Reliability of the Expanded Rehabilitation Complexity Scale
The RCS is a tool that can assess the need for complex rehabilitation and objectively indicate that a patient may have difficulty functioning well at home or in the community if their medical needs are still high.
- Trial name
- NCT06573359
- Testing
- questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Constipation, Neoplasms
Constipation in Pediatric Cancer Patients Receiving Vinca Alkaloids or Narcotics
This study will evaluate a questionnaire for measuring constipation in children with cancer. The questionnaire used in this study (Constipation Assessment Scale) reliably predicts the presence and severity of constipation in…
- Trial name
- NCT00032682
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Institutes of Health Clinical Center (CC)