Clinical trials: Pancreatectomy
Distal Pancreatectomy (DP)
Evaluation of Postoperative Outcomes and Mortality in Laparoscopic and Robotic Distal Pancreatectomy
Minimally invasive distal pancreatectomy can be performed using either a laparoscopic or robotic approach. These minimally invasive techniques are becoming increasingly common in the surgical treatment of both benign and…
- Trial name
- PREINSTRUCT (NCT07338409)
- Where
- Belgium
- Volunteers
- 126 people
- Sponsor
- Jessa Hospital
Pancreatectomy; Hyperglycemia, Diabete Mellitus
Glucose Metabolism After Partial Pancreatectomy
This is a single center observational study to assess alteration of glucose metabolism after pancreatectomy.
- Trial name
- NCT04409171
- Testing
- oral glucose tolerance test
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Distal Pancreatectomy, Spleen Preservation
Comparison of Outcomes Between Warshaw and Kimura Techniques for Spleen-preserving Minimally Invasive Distal Pancreatectomy
Spleen-persevering distal pancreatectomy (SP-DP) has been widely advocated as a routine procedure for benign or low-grade malignant tumors in the pancreatic body and tail, especially with a minimally invasive approach.
- Conditions
- Distal Pancreatectomy, Spleen Preservation, Postpancreatectomy Hemorrhage
- Trial name
- NCT06084975
- Testing
- Splenic vessels preservation
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Zhejiang University
Pancreatectomy, Pancreatoduodenectomy
Twenty Years of Pancreatic Surgery in Iceland
A retrospective analysis of patients undergoing pancreatic operations in Landspitali University Hospital, Reykjavik, Iceland, between 2003 and 2022.
- Conditions
- Pancreatectomy, Pancreatoduodenectomy, Distal Pancreatectomy (DP)
- Trial name
- NCT06738914
- Volunteers
- 244 people
- Sponsor
- Linkoeping University
Colectomy, Pancreatectomy
Implementation of a GDT Algorithm for Major Surgery Patients
This study examines the effect of an algorithm for GDT for patients undergoing major surgery under routine conditions.
- Conditions
- Colectomy, Pancreatectomy, Fluid Therapy
- Trial name
- NCT02509910
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Philipps University Marburg
Diabetes
Dexcom G6 for Total Pancreatectomy With Islet Autotransplantation (TPIAT) Patients
A single-center prospective trial on the effects of standard of care radiation exposure on the Dexcom G6 continuous glucose monitoring (CGM) device.
- Trial name
- NCT05607576
- Testing
- Uncovered CGM during radiologic procedures
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Deborah Elder
Congenital Hyperinsulinism (CHI), Persistent Hyperinsulinemic Hypoglycemia of Infancy (PHHI)
Phase II Safety and Efficacy Study of 18FDOPA PET-CT in Children With Hyperinsulinemic Hypoglycemia
Children with congenital hyperinsulinism (CHI) have low blood sugar, and some of these children may require surgery to remove part or all of their pancreas.
- Trial name
- 18FDOPA (NCT01468454)
- Testing
- 18 F-DOPA
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Children's Hospital of Philadelphia
Diabetes Mellitus
Risk Factors for the Development of Diabetes Mellitus After Distal Pancreatectomy
Glucose homeostasis changes after distal pancreatectomy are not well understood. This study aim to identify the incidence of and risk factors for, a change in glucose homeostasis in patients who underwent distal pancreatic…
- Trial name
- NCT03030209
- Testing
- Distal pancreatectomy
- Where
- China
- Volunteers
- 485 people
- Sponsor
- Peking Union Medical College Hospital
Pancreatectomy
Management of Traumatic Pancreas Transection
The goal of this observational study is to learn about the type of surgical effect on pancreas transection. The main questions aims to answer are: 1.
- Trial name
- NCT05856474
- Testing
- pancreatectomy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Cheng-Kung University Hospital
Islets of Langerhans Transplantation, Pancreatitis, Chronic
Clinical Outcome After Total Pancreatectomy With Islet Autotransplantation
A total pancreatectomy with islet autotransplantation (TPIAT) can be performed for a number of benign indications, such as chronic pancreatitis.
- Conditions
- Islets of Langerhans Transplantation, Pancreatitis, Chronic, Diabetes Mellitus
- Trial name
- TOPPER (NCT05287737)
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Leiden University Medical Center
Hyperinsulinism, Diabetes
Bionic Pancreas in Children With Hyperinsulinism and Post-Pancreatectomy Diabetes
This is a pilot study designed to determine if the bihormonal bionic pancreas provides improved blood glucose control, compared to the current standard of care, in individuals with hyperinsulinism who developed diabetes after…
- Conditions
- Hyperinsulinism, Diabetes, Pancreatic Diseases, Pancreatectomy; Hyperglycemia
- Trial name
- NCT03303196
- Testing
- Bihormonal Bionic Pancreas
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Pancreaticoduodenectomy, Distal Pancreatectomy
Randomized Trial of Early Versus Standard Drainage Removal After Pancreatic Resections
Despite a substantial decrease in postoperative mortality, morbidity after pancreatic resections is still high, even at high-volume centers.
- Conditions
- Pancreaticoduodenectomy, Distal Pancreatectomy, Pancreatic Fistula, Abdominal Abscess
- Trial name
- NCT00931554
- Testing
- Postoperative drain removal
- Where
- Italy
- Volunteers
- 114 people
- Sponsor
- Universita di Verona
Pancreatogenous Diabetes
Human Versus Analogue Insulin in Patients After Pancreatectomy.
Pancreatectomy is a common treatment modality for both benign and malignant pathologies. One of the most common complications after pancreatectomy is pancreatogenous diabetes mellitus.
- Trial name
- NCT04690309
- Testing
- Treatment with human insulin preparations or treatment with insulin analogues
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Polish Society of Diabetology
Pancreatitis, Chronic, Pancreatectomy; Hyperglycemia
A Prospective Observational Study of TPIAT
Multi-center, prospective, observational cohort study of patients undergoing total pancreatectomy with islet autotransplantation (TPIAT)
- Conditions
- Pancreatitis, Chronic, Pancreatectomy; Hyperglycemia, Pancreatitis
- Trial name
- POST (NCT03260387)
- Testing
- TPIAT
- Where
- 12 sites in United States
- Volunteers
- 433 people
- Sponsor
- University of Minnesota
Gastric Cancer
Multivisceral Resections for Locally Advanced Gastric Cancer
The goal of this observational study is to assess whether the postoperative course and survival of patients subject to multivisceral resections for locally advanced gastric cancer (cT4b) were affected by the extent of surgery.
- Trial name
- TOCCATA (NCT06103435)
- Testing
- Extent od surgical resection
- Where
- Poland
- Volunteers
- 1,476 people
- Sponsor
- Jagiellonian University
Overwhelming Post-Splenectomy Infection
Splenic Function After Spleen-Preserving Distal Pancreatectomy With Excision of Splenic Artery and Vein
The spleen may be removed due to benign hematologic disorders, such as idiopathic thrombocytopenic purpura and hereditary spherocytosis, or malignancies, such as lymphomas and leukemias.
- Trial name
- NCT00778362
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Distal Pancreatectomy, Postoperative Pancreatic Fistula
Comparison of Outcomes With Stapler Versus Hand-Sewn Closure After Minimally Invasive Distal Pancreatectomy
The incidence of postoperative pancreatic fistula (POPF) after Distal pancreatectomy (DP) remains high. Of the available mitigation strategies, high-quality closure of the pancreatic stump is fundamental.
- Trial name
- NCT05789459
- Testing
- Stapler, Suture
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Zhejiang University
Surgery
Learning Curves in Laparoscopic Distal Pancreatectomy: A Different Experience for Each Generation
This study compared the learning curves and outcome of Laparoscopic Distal Pancreatectomy between 'pioneers' and early adopters in terms of feasibility and proficiency using short term outcomes.
- Trial name
- NCT05595343
- Testing
- Laparoscopic distal pancreatectomy
- Volunteers
- 600 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Islets of Langerhans Transplantation, Diabetes Mellitus
Arginine-stimulated Indication of Early Outcome After Islet Transplantation
Through islet transplantation, functional β-cell mass can be restored. Allogeneic islet transplantation is a treatment modality for a select group of patients with complicated type 1 diabetes mellitus.
- Conditions
- Islets of Langerhans Transplantation, Diabetes Mellitus, Chronic Pancreatitis
- Trial name
- ALADDIN (NCT05540197)
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Leiden University Medical Center
Exocrine Pancreatic Insufficiency, Pancreatic Diseases
Special Investigation of LipaCreon on Long-term Use in Patients With Pancreatic Exocrine Insufficiency
This study aims at collecting the information related to the safety and effectiveness in the pancreatic exocrine insufficiency patients receiving the treatment with LipaCreon for a long term in order to evaluate the effective and…
- Conditions
- Exocrine Pancreatic Insufficiency, Pancreatic Diseases, Digestive System Diseases
- Trial name
- NCT01427725
- Testing
- Lipacreon
- Where
- 189 sites in Japan
- Volunteers
- 579 people
- Sponsor
- Mylan Inc.