Clinical trials: Pancreatitis
Pancreatic Cancer, Bile Duct Cancer
Trial on the Evaluation of Pylorus-ring in Pancreaticoduodenectomy
The purpose of this study is to clarify whether resecting pylorus-ring decreases delayed gastric emptying after pancreaticoduodenectomy and improves postoperative quality of life (QOL).
- Conditions
- Pancreatic Cancer, Bile Duct Cancer, Ampullary Cancer, Duodenal Cancer
- Trial name
- NCT00639314
- Testing
- pylorus-preserving pancreaticoduodenectomy, pylorus-resecting pancreaticoduodenectomy
- Where
- Japan
- Volunteers
- 130 people
- Sponsor
- Wakayama Medical University
Cystic Fibrosis, CFTR Gene Dysfunction
CFTR Related Pancreatitis Study
The main causes of acute recurrent pancreatitis (ARP) or chronic pancreatitis (CP) in children are defects in genes that have been associated to pancreatitis.
- Trial name
- NCT04274413
- Testing
- Beta Adrenergic Sweat Test
- Sponsor
- The Hospital for Sick Children
Choledocholithiasis With Acute Cholangitis (Diagnosis), Acute Pancreatitis Due to Gallstones
Complications After Endoscopic Retrograde Cholangiopancreatography
Retrospective study to analyze benign complications and malignancy risks after ERCP with sphincterotomy. All patients who received a ERCP with sphincterotomy for a benign disease will be included.
- Trial name
- ERCP (NCT04735224)
- Volunteers
- 500 people
- Sponsor
- Juan Carlos Martín del Olmo
Recurrent Acute Pancreatitis, Prevention
The Effect of Aspirin on Recurrent Acute Pancreatitis
Recurrent acute pancreatitis (RAP) was defined as two or more occurrences of acute pancreatitis, which was associated with higher percentages of morbidities and mortalities, lower patients' life quality and increased health-care…
- Conditions
- Recurrent Acute Pancreatitis, Prevention, Aspirin
- Trial name
- NCT06185621
- Testing
- 100mg aspirin
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Air Force Military Medical University, China
Acute Pancreatitis
Searching the Best Prognostic Factor in Out Come Evaluation in Patients With Acute Pancreatitis Admitted at Assiut University Hospitals
Acute pancreatitis (AP) is rapid-onset inflammation of the pancreas that varies in severity from a self-limiting mild illness to rapidly progressive multiple organ failure.
- Trial name
- NCT03259880
- Volunteers
- 100 people
- Sponsor
- Fady Refaat Edwar Nasrallah
Acute Pancreatitis Due to Gallstones, Acute Pancreatitis
PrEveNtion of Biliary Events After Acute Pancreatitis in NonSUrgicaL PAtients: PENINSULA Trial
Acute pancreatitis (AP) is a common condition and its main etiology is biliary. Cholecystectomy is the standard preventive treatment for recurrence of AP after admission.
- Trial name
- PENINSULA (NCT06409741)
- Testing
- Biliary sphincterotomy
- Where
- 5 sites in Spain
- Volunteers
- 126 people
- Sponsor
- Hospital General Universitario de Alicante
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pancreatitis, Lipase Increased
Lipase Levels and Coronavirus Disease 2019
Although COVID-19 disease due to Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the respiratory tract, heart and coagulation system, symptoms of gastrointestinal system involvement such as abdominal pain…
- Trial name
- NCT05601258
- Testing
- Age, gender, hospitalization and mortality rates will be compared
- Where
- Turkey (Türkiye)
- Volunteers
- 4,000 people
- Sponsor
- Uşak University
Pancreatitis, Acute, Pain, Acute
Comparison of the Effectiveness of Paracetamol With Ibuprofen or Paracetamol With Metamizole in Treating Pain in Acute Pancreatitis in Children
The aim of the study is to assess the effectiveness and tolerance of pain treatment in AP in children using intravenous paracetamol in combination with ibuprofen or paracetamol in combination with metamizole.
- Conditions
- Pancreatitis, Acute, Pain, Acute, Pancreatic Disease, Pancreatic Diseases
- Trial name
- NCT07024199
- Testing
- The initial pain assessment, Drug administration according to protocol (paracetamol + ibuprofen OR paracetamol + metamizol), The effectiveness of the treatment
- Where
- Poland
- Volunteers
- 78 people
- Sponsor
- Medical University of Warsaw
Chronic Pancreatitis, Acute Pancreatitis
Relationship of CP and AP
The present study aimed to determine the prevalence of AP attacks before the diagnosis of CP and further identified the potential associated factors for AP episodes.
- Trial name
- NCT04670705
- Testing
- patients' characteristics
- Volunteers
- 1,022 people
- Sponsor
- Changhai Hospital
Type 2 Diabetes (Treated With Exenatide or Other Oral Antidiabetic Therapies), Healthy Subjects (Treated With no Diabetes Therapies)
A Retrospective Cohort Study of Acute Pancreatitis in Relation to Use of Exenatide and Other Antidiabetic Agents
The purpose of this research was to assess the absolute and relative incidence of acute pancreatitis in persons initiating exenatide compared with persons initiating a different antidiabetic agent, and secondarily, persons…
- Trial name
- NCT01077323
- Testing
- exenatide, Other antidiabetic therapies, No diabetes therapy
- Where
- United States
- Volunteers
- 363,766 people
- Sponsor
- AstraZeneca
Chronic Pancreatitis, Diabetes
Coordinating and Data Management Center for the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer
The data management systems, auditing, and monitoring effort are supported by the MD Anderson Cancer Center Clinical Research Support Center (CRSC).
- Conditions
- Chronic Pancreatitis, Diabetes, Pancreatic Cancer
- Trial name
- NCT03058926
- Testing
- Data Management and Monitoring
- Where
- United States
- Volunteers
- 25,000 people
- Sponsor
- M.D. Anderson Cancer Center
Pancreatitis, Acute Necrotizing
Dexmedetomidine Hydrochloride in the Prevention of Organ Failure Following Severe Acute Pancreatitis
Cytokines such as such as TNF-a, IL-1, IL-6 correlate with the severity of pancreatitis.Neuroendocrine pathways, such as the sympathetic nervous system or parasympathetic nervous system, in turn, have some impact on the immune…
- Trial name
- DHPOFFSAP (NCT02691598)
- Testing
- Infusion
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Nanjing University School of Medicine
Chronic Pancreatitis, Geriatric
Safety and Efficacy of ESWL for Geriatric Patients With Chronic Pancreatitis
Pancreatic extracorporeal shock wave lithotripsy (P-ESWL) is recommended as the first-line treatment for pancreatic stones. However, how well P-ESWL performs in geriatric patients remains unclear.
- Conditions
- Chronic Pancreatitis, Geriatric, Extracorporeal Shock Wave Lithotripsy
- Trial name
- ESWL (NCT03373682)
- Where
- China
- Volunteers
- 1,404 people
- Sponsor
- Changhai Hospital
Acute Pediatric Pancreatitis
Early Oral Nutrition in Mild Acute Pediatric Pancreatitis
This is a prospective trial for children with the diagnosis of mild acute pancreatitis admitted to the hospital for continued management.
- Trial name
- NCT01423786
- Testing
- Early Oral Nutrition
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Nationwide Children's Hospital
Acute Pancreatitis Due to Gallstones
Inmediate Feeding Tolerance in Acute Pancreatitis
Objective: Determine tolerance of immediate oral intake (8 hours posterior to the beginning of treatment) against traditional management (early feeding at 48hr) in patients with mild acute pancreatitis of biliary origin.
- Trial name
- NCT03354065
- Testing
- TIME OF FEEDING
- Volunteers
- 59 people
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Autoimmune Pancreatitis, Pancreatic Cancer
To Differentiate Focal Autoimmune Pancreatitis From Pancreatic Cancer by Endoscopic Ultrasound
Autoimmune pancreatitis (AIP) is a special type of chronic pancreatitis mediated by autoimmunity. The classic manifestation of AIP is diffuse pancreatic enlargement, some of which are characterized by focal enlargement.
- Trial name
- NCT04834505
- Testing
- Diagnostic imaging modalities for validation sample, EUS for derivation sample
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Peking Union Medical College Hospital
Pancreatitis
Non-inferiority of Pharmacological Prevention Alone Versus Pancreatic Stents to Prevent Post-ERCP Pancreatitis
Pancreatitis is the most important complication of ERCP. The severity of this condition varies from mild to severe and can lead to prolonged hospitalization, surgical interventions, and even death.
- Trial name
- NCT02368795
- Testing
- Pancreatic Stent, Indomethacin, Isosorbide Dinitrate
- Where
- Iran
- Volunteers
- 400 people
- Sponsor
- Tehran University of Medical Sciences
Pancreatitis, Organ Failure, Multiple
PROOF: Pancreatitis-associated Risk Of Organ Failure
This is a prospective case control study that compares the initial immune response with severity and outcome in patients with acute pancreatitis.
- Trial name
- PROOF (NCT03075605)
- Volunteers
- 723 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh