Clinical trials: Paralysis
Cerebral Palsy
Walking in the HIBBOT: is Gait Improved?
The aim of the study is to assess the impact of the innovative walking aid HIBBOT on the functions, activity and participation of young children with Cerebral Palsy, in comparison with conventional walking aids.
- Trial name
- NCT04172324
- Testing
- HIBBOT, Standard Care
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universiteit Antwerpen
Mitochondrial Disorders, Mitochondrial Genetic Disorders
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
- Conditions
- Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes
- Trial name
- NAMDC (NCT01694940)
- Where
- 17 sites in United States, Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cerebral Palsy
Utility of Upper-Extremity Plyometrics in Children With Unilateral Cerebral Palsy
This study was set out to evaluate the effect of a 12-week upper extremity plyometric exercise (Plyo-Ex) on muscle strength and upper extremity function in children with hemiparetic cerebral palsy (Hemi-CP).
- Trial name
- NCT06980246
- Testing
- Plyometric Exercise, Standard exercise program
- Where
- Saudi Arabia
- Volunteers
- 58 people
- Sponsor
- Cairo University
Facial Paralysis, Facial Palsy
Turkish Validation of the Synkinesis Assessment Questionnaire (SAQ)
Peripheral facial palsy may result in synkinesis, a condition characterized by involuntary facial muscle movements that occur during voluntary facial expressions.
- Conditions
- Facial Paralysis, Facial Palsy, Bell Palsy
- Trial name
- NCT07750561
- Testing
- Synkinesis Assessment Questionnaire (SAQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Barış CELBEK
Malignant Neoplasm of Thyroid Gland
Trial on Intraoperative Neuromonitoring (IONM) in Thyroid Cancer Surgery.
Scientific objectives: Primary objective: To assess if the use of IONM can decrease the rates of temporary RLN palsy after thyroid cancer surgery Secondary objectives: To assess if the use of IONM can decrease permanent RLN palsy…
- Trial name
- ACTION (NCT04842994)
- Testing
- IONM tube
- Where
- India
- Volunteers
- 448 people
- Sponsor
- Tata Memorial Hospital
Cerebral Palsy
Cognitive Functioning in Children and Adolescents With Cerebral Palsy
Background: Cerebral palsy (CP) is characterized by motor impairment but commonly involves more widespread difficulties, including cognitive impairment.
- Trial name
- CPCog-Youth-DK (NCT05921422)
- Testing
- Cognitive assessment
- Where
- 2 sites in Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cerebral Palsy
Development of a Remote Therapy Protocol for Upper Limb Function Enhancement in Children With Cerebral Palsy
The perpose of this study: Development and demonstration of a teletherapy protocol to improve upper limb function in children with cerebral palsy.
- Trial name
- NCT06272760
- Testing
- Home-based hand-arm bimanual intensive training (Tele-HABIT)
- Where
- South Korea
- Volunteers
- 29 people
- Sponsor
- Samsung Medical Center
Cerebral Palsy
The Effect of Bispectral Index Monitoring on Recovery From Deep Sedation
The purpose of this study was to compare BIS (bispectral index) monitoring and clinical sedation scale assessment on the recovery time and propofol usage from deep propofol sedation in children with cerebral palsy who received…
- Trial name
- NCT04190082
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Yeungnam University College of Medicine
Cerebral Palsy
Repetitive Split-Belt Treadmill Perturbation in Children With Unilateral Cerebral Palsy
This study was designed to investigate the effect of repeated split-belt treadmill waking practice on gait symmetry, dynamic balance control, and locomotor capacity in adolescents with unilateral cerebral palsy (ULCP).
- Trial name
- NCT05350241
- Testing
- Split-belt treadmill training, Standard physical therapy
- Where
- Saudi Arabia
- Volunteers
- 52 people
- Sponsor
- Cairo University
Cerebral Palsy, Acquired Brain Injury
Assessment of the Psychophysical State During Rehabilitation Treatment With Lokomat
The use of robotic technologies in rehabilitation is an increasingly widespread practice in the health sector: the Lokomat is a medical device intended for walking rehabilitation, consisting of an exoskeleton, a treadmill and a…
- Conditions
- Cerebral Palsy, Acquired Brain Injury, Hereditary Spastic Paraplegia
- Trial name
- NCT05767268
- Testing
- Lokomat
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- IRCCS Eugenio Medea
Cerebral Palsy, Congenital
CIMT and BIMT Affect Functional Outcome in CP
The aim of this randomized controlled trial is to determine the effects of constraint induced movement therapy CIMT and BIM bimanual activities on functional outcome in hemiplegic CP.
- Trial name
- NCT04211623
- Testing
- Constraint induced movement therapy, Bimanual activities
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Cerebral Palsy, Neuromuscular Diseases
NDT Effectiveness Study
The purpose of this study is to determine whether there is a functional change in children with Cerebral Palsy (CP) and other neuromuscular disorders participating in Neurodevelopmental Treatment (NDT) intervention using the…
- Conditions
- Cerebral Palsy, Neuromuscular Diseases, Neurodevelopment Treatment
- Trial name
- NCT05070910
- Testing
- Therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- MultiCare Health System Research Institute
Progressive Supranuclear Palsy, Cognitive Impairment
Neuropsychological Evaluation for Early Diagnosis of PSP
The aim of this study is to better understand the nature of the cognitive decline in Progressive Supranuclear Palsy, the time of its development and the relation with the other cardinal features of the disease.
- Trial name
- NCT03478124
- Testing
- Cognitive evaluation
- Volunteers
- 112 people
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Cerebral Palsy (CP)
Ayres Sensory Integration Intervention for Children With Cerebral Palsy
This study will examine whether a 12-week Ayres Sensory Integration (ASI)-based physiotherapy program can improve motor skills and daily functioning in young children with cerebral palsy.
- Trial name
- ASI-CP-PT (NCT07895485)
- Testing
- Ayres Sensory Integration-Based Physiotherapy, Usual Physiotherapy and Rehabilitation
- Volunteers
- 30 people
- Sponsor
- Izgi Miray Demirbag
Lyme Disease
Peripheral Facial Paralysis Sequelae in Lyme Disease Among Children
Neuroborreliosis (NB) is the second most frequent manifestation of Lyme disease. Painful meningoradiculitis is the most common neurologic manifestation in adults while facial nerve palsy (FP) and lymphocytic meningitis is…
- Trial name
- LYMEPED (NCT03981874)
- Testing
- telephonic interview
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Cerebral Palsy, Muscle Disorder
A New Training to Enhance Physical Activity in Adolescents With Cerebral Palsy
The purpose of this research study is to test the feasibility and response of a new exercise protocol on improving physical activity in adolescents with cerebral palsy.
- Conditions
- Cerebral Palsy, Muscle Disorder, Physical Disability, Posture Disorders in Children
- Trial name
- FOLIC (NCT05865418)
- Testing
- Loaded high intensity training, High intensity circuit training (HICT)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Alabama at Birmingham
Cerebral Palsy
Task-oriented Game Therapy Using Enhances Functions in Children With Cerebral Palsy.
Cerebral Palsy is an umbrella definition that refers to a disorder that occurs after a problem affecting a person's brain functions and has symptoms such as sensory, motor and mental deficits.
- Trial name
- NCT06071182
- Testing
- Task-oriented Fruit ninja game
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Erzurum Technical University
Cerebral Palsy
Erythropoietin Therapy for Children With Cerebral Palsy
This randomized placebo-controlled trial aims to investigate the efficacy and safety of erythropoetin for children with cerebral palsy.
- Trial name
- NCT01650415
- Testing
- Erythropoietin
- Where
- South Korea
- Volunteers
- 11 people
- Sponsor
- Bundang CHA Hospital
Cerebral Palsy
Stellate Ganglion Block in Cerebral Palsy
The goal of this clinical trial is to test the efficacy of stellate ganglion block in children with cerebral palsy and dysphagia.
- Trial name
- NCT06319508
- Testing
- routine rehabilitation treatment, Stellate ganglion block, Lidocaine hydrochloride
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Neurodegeneration, G-CSF
Neuroregenerative Potential of Intravenous G-CSF and Autologous Peripheral Blood Stem Cells
The current study describes a randomized, double-blind, cross-over study of intravenous G-CSF followed by infusion with autologous mobilized peripheral blood mononuclear cells (mPBMCs) in children with cerebral palsy (CP) to…
- Conditions
- Neurodegeneration, G-CSF, Peripheral Blood Mononuclear Cells, Cerebral Palsy
- Trial name
- NCT02983708
- Testing
- Peripheral blood mononuclear cells (mPBMC), G-CSF
- Volunteers
- 57 people
- Sponsor
- Hanyang University Seoul Hospital
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