Clinical trials: Parasomnia
Delayed Sleep Phase Syndrome
Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens
Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their…
- Trial name
- CARRS-P2 (NCT04792697)
- Testing
- Increase morning bright light, Decrease evening blue light, Sleep Scheduling
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Postoperative Sleep Quality, Postoperative Behaviour
Sleep Quality - Comparing the Effect of Ondansetron or Dexamethasone Given as Routine Prophylaxis Intraoperatively to Prevent Post Operative Nausea and Vomiting (SCORPION)
Nausea and vomiting are common complications after anaesthesia, and anaesthetists routinely give medications to prevent them. Dexamethasone and ondansetron are the two most commonly used agents and have a long safety record.
- Conditions
- Postoperative Sleep Quality, Postoperative Behaviour, Postoperative Recovery in Children, Postoperative Nausea and Vomiting (PONV)
- Trial name
- SCORPION (NCT07777276)
- Testing
- Dexamethasone (IV), Ondansetron iv
- Where
- 3 sites in Australia, Brazil
- Volunteers
- 500 people
- Sponsor
- Telethon Kids Institute
Obstructive Sleep Apnea, Down Syndrome (Trisomy 21)
Oro-myofunctional Characteristics and Obstructive Sleep Apnea in Infants With Down Syndrome
Obstructive Sleep Apnea (OSA) is characterised by repetitive collapse of the upper airway during sleep, inducing breathing disturbances that can result in oxygen desaturation and frequent arousals.
- Trial name
- OMF21 (NCT07195253)
- Testing
- Polysomnography (PSG) to explore OSA, Oro-myo-functional clinical evaluation, Sleep Disturbance Scale for Children
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Sleep Apnea, Pediatric Sleep Apnea
Use of a 3D Printer to Make Custom Sleep Masks for Positive Airway Pressure Treatment
This is a small pilot study to look at the feasibility of creating a customized sleep mask for use with Continuous Positive Airway Pressure (CPAP) or other similar treatments for sleep apnea.
- Trial name
- NCT02896751
- Testing
- 3D printed NIV mask
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Sleep Apnea, Obstructive, Sleep Apnea Syndromes
Continuous Positive Airway Pressure (CPAP) After Adenotonsillectomy in Children
Obstructive sleep-disordered breathing (SDB) affects 2-3% of children and may lead to problems with nighttime sleep and daytime behavior, learning, sleepiness, and mood.
- Conditions
- Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Child Behavior Disorders, Attention Deficit Disorder With Hyperactivity
- Trial name
- NCT01554527
- Testing
- CPAP treatment, No CPAP treatment
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Nonorganic Insomnia, Neurodevelopmental Disorders
Better Nights, Better Days for Children With Neurodevelopment Disorders
More than 90% of children with neurodevelopmental disorders (NDD) experience sleep problems, whereas less than 25% of typically developing children experience sleep problems.
- Conditions
- Nonorganic Insomnia, Neurodevelopmental Disorders, Primary Insomnia
- Trial name
- BNBD-NDD (NCT02694003)
- Testing
- BNBD-NDD Intervention
- Where
- Canada
- Volunteers
- 218 people
- Sponsor
- IWK Health Centre
Delirium in the Intensive Care Unit, Sleep Quality in Adult ICU Patients
Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients
This is a pilot feasibility study examining the use of immersive virtual reality (VR) in adult intensive care unit (ICU) patients.
- Conditions
- Delirium in the Intensive Care Unit, Sleep Quality in Adult ICU Patients, Agitation Associated With Critical Illness, Anxiety Acute
- Trial name
- NCT07649876
- Testing
- Virtual reality (VR) therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Depressive Symptoms, Anxiety Symptoms
Culturally Adapted i-CBT for Farsi/Dari Speaking Migrants
The aim of this randomized controlled trial (RCT) is to investigate the effectiveness of a culturally adapted internet-based cognitive behavioral therapy (i-CBT) intervention in reducing symptoms of common mental health issues…
- Conditions
- Depressive Symptoms, Anxiety Symptoms, Grief, Psychological Trauma
- Trial name
- i-CBT (NCT06828276)
- Testing
- Culturally adapted i-CBT
- Where
- Sweden
- Volunteers
- 93 people
- Sponsor
- Karolinska Institutet
Sleep Disordered Breathing
Peak(R) vs. Electrocautery in Children Undergoing Tonsillectomy With Adenoidectomy
Given the large numbers of children who undergo tonsillectomy (by the time a child is 15 years old, 13% of his/her peers will have had a tonsillectomy), the significant morbidity, and direct and indirect costs associated with…
- Trial name
- NCT02533999
- Testing
- PEAK® Plasma System, Electrosurgery
- Volunteers
- 75 people
- Sponsor
- Nemours Children's Clinic
Disturbances in Initiating and Maintaining Sleep, Parent-Child Relations
Play2Sleep: Using Play to Improve Infant Sleep
The objective of this study is to evaluate and explore the effectiveness of Play2Sleep on families of infants with infant sleep disturbances.
- Trial name
- NCT02742155
- Testing
- Play2Sleep, Comparison
- Where
- 9 sites in Canada
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Postpartum Depression, Sleep Disorder
The Effects of Pregnancy Classes and Contributing Factors to Postpartum Depression
It is recommended by the American College of Obstetricians and Gynecologists' Committee on Obstetric Practice that all obstetricians screen each women for postpartum depression and anxiety with a validated instrument.
- Conditions
- Postpartum Depression, Sleep Disorder, Breast Feeding, Self Esteem
- Trial name
- NCT03763435
- Testing
- Antenatal pregnancy classes
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Bartin State Hospital
Insomnia
Effectiveness of a Guided Self-help Intervention for Improving Sleep in University Students
This randomized controlled trials aims to assess the effectiveness of an online guided self-help intervention ('i-Sleep \& BioClock') based on CBTi principles for university students' sleep problems.
- Trial name
- NCT06023693
- Testing
- i-Sleep & BioClock, Online Psychoeducation
- Where
- Netherlands
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Early Onset Dementia, Young Onset Dementia
Anxiety, Stress and Sleep Problems in People With Early Onset Dementia
The aim of this study is to detect and assess needs of people with early onset dementia regarding anxiety, stress and sleep implement a 6 week intervention pilot study in wich weekly (hourly) sessions are implemented in day care…
- Conditions
- Early Onset Dementia, Young Onset Dementia, Stress, Distress, Emotional
- Trial name
- Young-D (NCT05555381)
- Testing
- young-D program
- Where
- 2 sites in Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Obstructive Sleep Apnea, Tonsillitis
Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery
A RCT to compare hydromorphone versus fentanyl for pain control following tonsillectomy or adenotonsillectomy surgery.
- Trial name
- NCT04230681
- Testing
- Hydromorphone, Fentanyl
- Where
- United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Sleep Quality, Communication
Effect of Skin-to-skin Contact on Interaction and Parents' Sleep
This study evaluates the effect of a late intervention of continuous skin-to-skin contact (SSC) in the neonatal intensive care unit (NICU).
- Conditions
- Sleep Quality, Communication, Stress Reaction
- Trial name
- Neo-SIPaS (NCT03004677)
- Testing
- Continuous skin-to-skin contact, Standard Care
- Where
- 3 sites in Sweden
- Volunteers
- 11 people
- Sponsor
- Linkoeping University
Prader-Willi Syndrome, Excessive Daytime Sleepiness
Impact of Bright Light Therapy on Prader-Willi Syndrome
This is a placebo controlled clinical trial to assess the utility of light therapy as a sufficient treatment for excessive daytime sleepiness in patients with Prader-Willi Syndrome
- Conditions
- Prader-Willi Syndrome, Excessive Daytime Sleepiness, Hyperphagia, Body Weight
- Trial name
- PWS-LT (NCT05939453)
- Testing
- Bright Light Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Maimonides Medical Center
Obstructive Sleep Apnea
Fentanyl Test in Children's Adenotonsillectomy
The purpose of this study is to discuss the relationship between the result of fentanyl test and required dosage of morphine for children with OSAS after adenotonsillectomy；and to evaluate the ability of predicting requested…
- Trial name
- NCT02484222
- Testing
- Fentanyl
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Sleep Problem, Behavior, Child
Parents Advancing Toddler Health
Although early interventions can improve health equity in young children living in poverty, this promise often is not realized because of barriers to family engagement.
- Trial name
- PATH (NCT04824989)
- Testing
- Sleep Health in Preschoolers (SHIP), Family Check-Up (FCU), Oral Health, Child Safety, and Environmental Health Intervention (Active Control)
- Where
- 2 sites in United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Obstructive Sleep Apnea
Effect of Ketorolac on Post Adenotonsillectomy Pain
This randomized prospective study aims to determine the effect of ketorolac on the total dose of morphine required to achieve postoperative analgesia in children with obstructive sleep apnea (OSA) undergoing adenotonsillectomy.
- Trial name
- NCT03467750
- Testing
- Ketorolac, Standard of Care
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Emory University
Obstructive Sleep Apnea, Down Syndrome
Medications for Obstructive Sleep Apnea In Children With Down Syndrome
This is a randomized, double blind, cross-over study of the combination of atomoxetine and oxybutynin (ato-oxy) in children with DS and OSA documented by polysomnography (PSG).
- Trial name
- MOSAIC (NCT04115878)
- Testing
- Atomoxetine and oxybutynin (ato-oxy)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Arizona