Clinical trials: Parodontitis
Alzheimer Disease, Periodontitis
Periodonitis and Alzheimer's Disease
The main objective of this study is to assess whether Periodontal Disease is more prevalent in adult patients diagnosed with Alzheimer's Disease compared to adult patients without Alzheimer's Disease.
- Trial name
- NCT05189132
- Testing
- Periodontal Diagnosis, Microbiological analysis, Inflammatory mediators
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Apical Periodontitis
In Vivo Assessment of Endodontics Procedures
In view of the wide variety of mechanized endodontic instrumentation systems, the ideal would be that the choose of this system based on the anatomical characteristics of the canal and the biological precepts.
- Trial name
- NCT03243357
- Testing
- TF Adaptive (First Apical Binding File), TF Adaptive (Control)
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Federal University of Uberlandia
Intracanal Medicament
Comparison of Inter-appointment Pain Reduction During Root Canal Treatment in Symptomatic Apical Periodontitis by Using Intracanal Medicaments; Chlorhexidine Gel and Single Antibiotic Paste Nitrofurantoin
This study is being conducted to find out which of two medications-Chlorhexidine Gel or Nitrofurantoin-works better in reducing pain between root canal treatment visits.
- Trial name
- NCT07198919
- Testing
- Chlorhexidine gel, Nitrofurantoin 100 MG
- Where
- Pakistan
- Volunteers
- 220 people
- Sponsor
- Altamash Institute of Dental Medicine
Diabetes Mellitus, Periodontal Disease
Periodontal Treatment With Diode Laser in the Patients With Diabetes Melitus
This study aimed to investigate the effects of diode laser (DL) in addition to non-surgical periodontal treatment on periodontal parameters, systemic inflammatory response, and serum hemoglobin A1c (HbA1c) level in patients with…
- Trial name
- NCT03444363
- Testing
- Laser group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Apical Periodontitis
The Effect of Human Umbilical Cord Mesenchymal Stem Cells and Exosomes on the Healing of Postoperative Pain and Periapical Lesions in the Treatment of Apical Periodontitis: Randomized Controlled Clinical Study
The main purpose of this study is to evaluate the effect of Mesenchymal Stem Cells (MSCs) isolated from the umbilical cord and exosomes derived from these cells on the success of the treatment in the regenerative endodontic…
- Trial name
- NCT06764004
- Testing
- Stem Cell Product, Bleeding and clots
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Periodontitis, Juvenile
Chairside Mouthrinse Test and Cost Effectiveness
The aim is to study whether participants at risk could be identified using an aMMP-8 chairside mouth rinse test and to study if oral health and health behaviour is linked to the test result in Finnish adolescents.
- Trial name
- JuvePar (NCT04139863)
- Testing
- aMMP-8 chairside test
- Where
- Finland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Chronic Periodontitis
Hyaluronic Acid With Scaling & Root Planing In Chronic Periodontitis Patients With Diabetes Mellitus Type 2
The present study aimed to assess the adjunctive use of Hyaluronic acid with scaling \& root planing (SRP) in patients with chronic periodontitis \& diabetes mellitus type 2.
- Trial name
- NCT03807596
- Testing
- Periodontal treatment with Hyaluronic acid associated with SRP, Scaling & root planning alone
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Periodontal Diseases
Effect of Intracanal Medicaments on Post-Operative Pain in Symptomatic Apical Periodontitis: An RCT
Comparison of different intracanal medicaments during root canal treatment to assess their effect on post-operative pain in teeth with Symptomatic Apical Periodontitis
- Trial name
- NCT07123792
- Testing
- Calcium Hydroxide (20%), Chlorhexidine Gel (2%), Modified Triple Antibiotic Paste
- Where
- Pakistan
- Volunteers
- 480 people
- Sponsor
- HITEC-Institute of Medical Sciences
Dental Caries in Children, Dental Plaque
Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases
The aim of the study is to identify adolescent patients that are at risk of developing oral diseases, and to assess if targeted preventive oral treatment with antibacterial dual-light therapy as an adjunctive treatment method can…
- Conditions
- Dental Caries in Children, Dental Plaque, Tooth Decay, Periodontitis
- Trial name
- LumoPrevent (NCT06286501)
- Testing
- Lumoral Treatment, Standard, personalized oral health care
- Where
- Finland
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Wellbeing Services County of Pirkanmaa
Periapical Periodontitis, Tooth Diseases
Regenerative Endodontic Procedure of Immature Permanent Teeth With Apical Periodontitis Using PRF
This study evaluates the clinical effect of regenerative endodontic procedure using PRF in immature permanent teeth with apical periodontitis.
- Conditions
- Periapical Periodontitis, Tooth Diseases, Stomatognathic Diseases
- Trial name
- NCT02801552
- Testing
- PRF
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Apical Periodontitis
Clinical and Radiographic Success of Regeneration Using Injectable Platelet Rich Fibrin
Study aimed at assessing the clinical and radiographic success of pulp regeneration using injectable platelet-rich fibrin in mature permanent molars with apical periodontitis versus root canal treatment using Gutta Percha (GP)…
- Trial name
- NCT06086249
- Testing
- Regeneration using Injectable platelet-rich fibrin, Root canal treatment
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis, Endodontic Inflammation
Endo-perio Lesion's Treatment With Using Diode Laser 940nm
Periodontal marginal and periapical diseases cause a huge destruction of tissues surrounding the tooth with periodontal patients.
- Trial name
- NCT04628845
- Testing
- Endo-perio therapy with laser 940nm, Endo-perio therapy without laser 940nm
- Where
- 3 sites in Poland
- Volunteers
- 20 people
- Sponsor
- Pomeranian Medical University Szczecin
Periodontitis
Running Title: PPAR-γ, RXR-α, and VDR Expressions in Periodontitis
Objective: The present study aimed to determine the expressions of nuclear receptors PPAR (Peroxisome proliferative activator receptor)-γ, RXR (Retinoid X receptor)-α, and vitamin D receptor (VDR) in healthy volunteers and…
- Trial name
- NCT04018144
- Testing
- Gingiva Biopsy Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Systemic Sclerosis, Periodontitis
Periodontal Health Status in Patients with Systemic Sclerosis
The aim of the research will be to evaluate the effects of NSPT on clinical periodontal parameters, level of antioxidants in unstimulated saliva and the levels of biomarkers (VEGF, TGF-β, IL-17) in the GCF in SSc patients in…
- Trial name
- NCT05215431
- Testing
- periodontal examination's, determination of salivary antioxidants and cytokine levels (VEGF, TGF-β, Il-17) in gingival crevicular fluid, Non-surgical therapy of periodontitis, Activity of antioxidants in unstimulated saliva (GPX, SOD, UA), Total cytokine levels (VEGF, TGF-β, Il-17) in gingival crevicular fluid
- Where
- Serbia
- Volunteers
- 60 people
- Sponsor
- University of Belgrade
Alveolar Bone Loss, Periodontitis
Intraoral Ultrasound Imaging of Tooth-periodontium Complex
Misaligned teeth are very common in the population and are commonly known as malocclusion. This happens when the upper teeth do not align properly with the lower teeth.
- Trial name
- NCT04971642
- Testing
- Intraoral ultrasound
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Dental Pulp Necrosis, Periapical Periodontitis
Measurement of Bite Force in Humans
This protocol is for a clinical trial to evaluate the reliability of the bite fork as a diagnostic instrument in subjects with pulpal necrosis and apical periodontitis.
- Trial name
- NCT00223327
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio