Clinical trials: Partial
Epilepsy, Rolandic
HEAD-Study Optimizing the Treatment of Children With BECTS
The investigators hypothesize that Levetiracetam is as effective as Sulthiame in the treatment of children with BECTS. Patients entering the HEAD-Studie are either treated with Leveitracetam or Sulthiame over a 6 months period.
- Trial name
- HEAD (NCT00471744)
- Testing
- Treatment with levetiracetam or sulthiame over a six-month period.
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Dental Caries in Children
Partial or Complete Excavation of Deep Caries in Primary Molars
Background: The traditional approach of carious lesions with risk for progression has has been to excavate all infected and demineralised tissue before placement of the restoration.
- Trial name
- PBRN (NCT04614285)
- Testing
- Partial excavation
- Where
- Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Pulpotomy, Tooth, Deciduous
Biodentine Partial Pulpotomy of Pulpally Exposed Primary Molars
Objective: To compare success rates of biodentine partial pulpotomy versus formocresol pulpotomy treatment of pulpally exposed lower primary molars.
- Trial name
- NCT02393326
- Testing
- partial pulpotomy with biodentine, Formocresol pulpotomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Full Spectrum
A Self-controlled Study of the Effect of Partial Spectral Absence of Visible Light on the Pupil
Previous studies have shown that the spectrum of light influences myopia. LED lights with a partially absent light spectrum increase the risk of myopia progression compared to LEDs with a full spectrum, potentially mediated by…
- Trial name
- NCT06501131
- Testing
- full-spectrum light exposure, specific spectrum absence light exposure
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Pulpitis - Irreversible, Resorption, Root
The Effect of Using 70% Ethanol Alcohol as a Root Canal Irrigant on Increasing the Success Rate of Metapex in Pulpectomy Compared to Normal Saline in Primary Molars
The aim of the study is to perform a clinical and radiographic evaluation of 70% Ethanol Alcohol versus Normal Saline as root canal irrigating solutions in partial pulpectomy of primary molars with Metapex.
- Conditions
- Pulpitis - Irreversible, Resorption, Root, Abscess Bone, Mobility, Tooth
- Trial name
- NCT04669392
- Testing
- 70% Ethanol Alcohol
- Volunteers
- 20 people
- Sponsor
- Cairo University
Burn Injury, Soft Tissue Injury
Phase I Study for Autologous Dermal Substitutes and Dermo-epidermal Skin Substitutes for Treatment of Skin Defects
The purpose of this study is the evaluation of the safety of autologous tissue-engineered dermal substitutes "denovoDerm" (first arm) and dermo-epidermal skin substitutes "denovoSkin" (second arm) transplanted onto the wound bed…
- Conditions
- Burn Injury, Soft Tissue Injury, Skin Necrosis, Scars
- Trial name
- NCT02145130
- Testing
- denovoDerm, denovoSkin
- Where
- 2 sites in Switzerland
- Volunteers
- 12 people
- Sponsor
- University of Zurich
Cystic Fibrosis
A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation
The purpose of this study is to evaluate the safety and efficacy of treatment with VX-371 in hypertonic saline compared to hypertonic saline alone in subjects with cystic fibrosis (CF) who are ≥12 years of age, homozygous for the…
- Trial name
- NCT02709109
- Testing
- VX-371 + HS, Hypertonic saline, Orkambi
- Where
- 40 sites in United States, France and 2 more
- Volunteers
- 147 people
- Sponsor
- Parion Sciences
Carious Teeth
Evaluation of Partial Versus Complete Pulpotomy in Carious Immature Molars Permanent Teeth Using Bioceramic Material
One of our major concerns and daily challenges is the management of carious immature permanent teeth, also known as young permanent teeth while preserving the vitality of the dental.
- Trial name
- NCT06101550
- Testing
- partial pulpotomy, Complete pulpotomy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spinal Cord Injury
Effects of System Suspended Robotic Lokomat Gait in Patients With Incomplete Spinal Cord Injury
Patients with incomplete spinal cord injury
- Trial name
- NCT02342080
- Testing
- Training sessions, Lokomat system (Hocoma AG Switzerland)
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo General Hospital
Complete Contact, Incomplete Contact
Comparison of Post-operative Knee Range of Motion and Functions Between Intraoperative Complete and Incomplete Patellofemoral Articular Contacts in Patients Undergoing Total Knee Arthroplasty
The purpose of this study is to compare clinical outcome in knee range of motion and functions between intraoperative complete and incomplete patellofemoral articular contacts
- Trial name
- NCT05349461
- Testing
- Complete patellofemoral articular contact, Incomplete patellofemoral articular contact
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Navamindradhiraj University
Dental Caries Extending to Pulp, Molar Incisor Hypomineralization
Vital Pulp Therapy in Carious Teeth With Hypomineralization
Vital pulp therapy (VPT) is a general term for multiple procedures (indirect pulp cap, direct pulp cap and pulpotomy) all directed toward preserving pulp vitality and enable complete root development in immature teeth.
- Trial name
- NCT03735069
- Testing
- IPT (Indirect pulp treatment), Cvek/partial pulpotomy, Cervical pulpotomy
- Where
- Jordan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Hereditary Angioedema (HAE)
Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1 Esterase Inhibitor for the Prevention of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema
The purpose of this study is to assess the efficacy and safety of subcutaneous administration of a liquid formulation of C1 esterase inhibitor for the prevention of angioedema attacks in adolescent and adult subjects with…
- Trial name
- NCT02584959
- Testing
- C1 esterase inhibitor [human] liquid
- Where
- 27 sites in United States, Canada and 5 more
- Volunteers
- 75 people
- Sponsor
- Shire
Rotator Cuff Tears
Comparison Between Arthroscopic Debridement and Repair for Partial-thickness Rotator Cuff Tears
The purpose of this study is to conduct a prospective randomized controlled trial to compare the effects of arthroscopic debridement and repair for Ellman grade II bursal-side partial-thickness rotator cuff tears.The hypothesis…
- Trial name
- NCT04710966
- Testing
- arthroscopic debridement, arthroscopic repair
- Where
- China
- Volunteers
- 179 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Necrotic Primary Teeth
Evaluation of Antimicrobial Potency of Garlic Lemon Extract Irrigant Versus Physiological Saline Irrigant
To evaluate the antimicrobial potency of Garlic Lemon extract irrigant versus physiological saline irrigant following partial pulpectomy in primary molars.
- Trial name
- NCT06759766
- Testing
- Garlic-Lemon Extract irrigant, physiological saline
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Seizures, Epilepsies, Partial
Efficacy and Safety of Diazepam in the Management of Refractory Epilepsy in Selected Patients Who Require Intermittent Medical Intervention for Acute Repetitive Seizures.
To evaluate the efficacy and safety of diazepam in the management of refractory epilepsy in selected patients who require intermittent medical intervention for the control of episodes of acute repetitive seizures.
- Conditions
- Seizures, Epilepsies, Partial, Epilepsy, Complex Partial, Epilepsy, Generalized
- Trial name
- NCT00319501
- Testing
- Vanquix Auto-Injector (Diazepam Injection)
- Where
- 86 sites in United States
- Volunteers
- 234 people
- Sponsor
- Pfizer
Epilepsies, Partial, Epilepsy, Tonic-Clonic
Microburst Vagus Nerve Stimulator (VNS) Therapy Feasibility Study
Evaluate the initial safety and effectiveness of Microburst VNS stimulation in subjects with refractory epilepsy.
- Trial name
- Microburst (NCT03446664)
- Testing
- Microburst Stimulation
- Where
- 9 sites in United States, Belgium
- Volunteers
- 33 people
- Sponsor
- LivaNova
Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis
Buprenorphine for the Management of Pain in Children With Sickle Cell Disease
The goal of this clinical trial is to learn whether a single dose of buccal buprenorphine (BELBUCA) is safe when used in place and/or with full agonist opioids that would otherwise be started during a sickle cell pain crisis…
- Conditions
- Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis, Sickle Cell Anemia Crisis, Sickle Cell Anemia in Children
- Trial name
- NCT07799571
- Testing
- Buprenorphine Buccal Film [Belbuca]
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Natasha Archer
Myopia
Myopic Control for High Myopes Using Orthokeratology
The purpose of this study is to evaluate and compare the eyeball elongation in high myopic children using partial correction orthokeratology and single-vision spectacles.
- Trial name
- HM-PRO (NCT00977236)
- Testing
- Orthokeratology lenses, Single-vision spectacle lenses
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Renal Cell Carcinoma, Robotic Surgical Procedures
Evaluation of the Safety of Reoperation for Ipsilateral Recurrent Tumors After Nephron-sparing Partial Nephrectomy
To evaluate the safety of reoperation in patients with renal tumors who have ipsilateral tumor recurrence after nephron-sparing partial nephrectomy.
- Trial name
- LiangAH (NCT06317207)
- Volunteers
- 15 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Focal Epilepsy
Clinical Efficacy and Safety of Perampanel Monotherapy in the Treatment of Children With Focal Epilepsy
This project is a multicenter prospective study. By retrieving outpatient medical records and collecting clinical data of epilepsy patients, the efficacy and safety of single-drug perampanel in patients with focal epilepsy were…
- Trial name
- NCT05497193
- Testing
- perampanel
- Where
- China
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Yang Xinwei