Clinical trials: Pathologic Fracture
Atrial Septal Defect (ASD), Dexmedetomidine
Effect of Dexmedetomidine Supplementation to General Anaesthesia in Paediatric Transcatheter Closure of Atrial Septal Defect
The aim of this randomized trial is to determine efficacy of dexmedetomidine in improving quality of recovery in pediatric patients undergoing interventional catheter closure of ASD while maintaining the hemodynamic parameters.
- Conditions
- Atrial Septal Defect (ASD), Dexmedetomidine, Delirium - Postoperative, Stress Response
- Trial name
- NCT06631534
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Bone Fractures
Opioid Management for Discharged Emergency Department Patients
The goal of this study is to analyze the use of the Addinex system for opioid dispensing after ambulatory care to determine whether it will reduce opioid consumption, increase pill disposal, show variables that may predict opioid…
- Trial name
- NCT06592378
- Testing
- Addinex, Standard Pill Bottle
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Addinex Technologies, Inc.
Distal Radius Fracture Reduction, Pain Control
Pain Control Alternatives in Pediatric Patients With Distal Radius Fractures
The aim of this study is to evaluate the efficacy of a hematoma block and minimal ketamine pain control or hematoma block and intranasal fentanyl in pediatric patients presenting with distal radius fractures requiring reduction…
- Conditions
- Distal Radius Fracture Reduction, Pain Control, Pediatric Fractures
- Trial name
- NCT07120763
- Testing
- Ketamine + Lidocaine, Ketamine group, Fentanyl (Nasalfent, Fentanyl Citrate Nasal Spray)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- State University of New York at Buffalo
Back Pain, Stress Fracture
Posterior Lumbar Stress Reaction in Pediatric Patients. Treatment With or Without Soft Spinal Brace?
A clinical trial will be conducted comparing healing of a posterior lumbar vertebra stress reaction in children treated either with cessation of sports activities for a period of six weeks and wearing a soft spinal brace 16 hours…
- Trial name
- NCT04533178
- Testing
- soft spinal brace, Resting from all sports activities
- Where
- 4 sites in Finland
- Volunteers
- 110 people
- Sponsor
- Turku University Hospital
Fractures, Bone, Upper Extremity Injury
Ultrasonography in Fracture Management
The bone fracture is usually diagnosed using an X-ray examination (the method of choice). However, in the case of the youngest patients (children and adolescents), it carries a potential risk of X-ray radiation exposure.
- Conditions
- Fractures, Bone, Upper Extremity Injury, Healing Fracture of Bone, Vascularization
- Trial name
- UFrac (NCT04501510)
- Testing
- Ultrasonographic examination validation and testing
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- University of Warmia and Mazury
Fractures, Closed, Humeral Fractures
Regional Blocks for Lateral Condyle Fractures
The purpose of this study is to investigate the post-operative pain control in pediatric patients with closed lateral condyle fractures who undergo open reduction and percutaneous pinning.
- Conditions
- Fractures, Closed, Humeral Fractures, Pain
- Trial name
- NCT03796572
- Testing
- Ropivacaine, Puncture Wound and Dressing
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Surgical Wound Infection
Duration of Postoperative Antibiotic Prophylaxis in Facial Fractures
Facial fractures make up a significant proportion of injuries in trauma patients. Treatment of these fractures often results in standard surgical interventions.
- Trial name
- NCT01583062
- Testing
- Amoxicillin/clavulanic acid
- Where
- Switzerland
- Volunteers
- 217 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hip Fractures, Stroke
Feasibility of the Geriatric Activation Program Pellenberg With Caregiver Involvement
This interventional study aims to see if involving caregivers as exercise partners with the physiotherapist throughout in-hospital geriatric rehabilitation and the first six weeks following discharge is feasible.
- Conditions
- Hip Fractures, Stroke, Frailty
- Trial name
- NCT05419284
- Testing
- GAPP+Care, +Care, Observation of GAPP+Care
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Trauma (Including Fractures), Facial Bones Fracture
Haemorrhage From Severe Neck and Facial Injuries - Characteristics, Management and Outcomes
This is a descriptive observational study of trauma patients admitted to the Trauma Unit at the Karolinska University Hospital Solna, Stockholm, Sweden.
- Conditions
- Trauma (Including Fractures), Facial Bones Fracture, Neck Injuries
- Trial name
- NCT07204405
- Volunteers
- 15,000 people
- Sponsor
- Karolinska University Hospital
Postoperative Pain
Efficacy of Piroxicam as a Perioperative Analgesic for Patients Undergoing Fixation of Maxillofacial Fractures
At Eldemerdash Hospital at Ain Shams University in Egypt, 72 adult patients (16 to 25 years old) who had mandibular or maxillary fractures were treated with open reduction and internal stabilization.
- Trial name
- NCT04062591
- Testing
- Piroxicam group
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Mandibular Fractures
Evaluation of Customized V Plate Versus Conventional Miniplates of Mandibular Angle Fracture
The aim of the study to evaluate the effect of customized V pattern plate fixation versus a conventional superior-inferior mini plates fixation of mandibular angle fracture on mouth opening and radio graphical parameters.
- Trial name
- NCT03761524
- Testing
- Customized V plate fixation, Conventional miniplates fixation
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Cementation Teeth; Hyperplasia, Dental Cements
Cementation Techniques; an In-vitro Study
The goal of this observational study invitro study was to compare the different cementation techniques used to lute full veneer crowns on extracted and prepared teeth using Glass Ionomer Cement type 1.
- Conditions
- Cementation Teeth; Hyperplasia, Dental Cements, Tooth Crown Fracture
- Trial name
- NCT05875688
- Testing
- Cementation Technique A, Cementation Technique B, Cementation Technique C
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Femoral Neck Fractures
Practice Survey on Femoral Neck Fractures and the Incidence of Type of Anesthesia on Patient Outcome
Inclusion of all patients with femoral neck fracture presenting in Saint-Luc Bouge Hospital between October 1th 2014 and September 30th 2015.
- Trial name
- NCT02198820
- Testing
- General Anesthesia, Loco Regional Anesthesia
- Where
- Belgium
- Sponsor
- Astes
Skull Fractures, Stroke
Simulation Training in Emergency Department Imaging 2
Background and study aims: Computerised Tomography (CT) head scans are frequently requested by Emergency Department (ED) clinicians as one of the investigations for their patients.
- Conditions
- Skull Fractures, Stroke, Intracranial Bleed, Brain Tumor
- Trial name
- STEDI2 (NCT05427838)
- Testing
- Online training
- Where
- 6 sites in United Kingdom
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Elbow Fracture
Percutaneous Pin Removal in Children - is Analgesia Necessary?
This is a simple randomised clinical trial to study if non-narcotic analgesia reduces the pain score and pulse rate of children who undergo removal of percutaneous pins in the outpatient clinic.
- Trial name
- NCT01944085
- Testing
- Acetaminophen, Ibuprofen, Vitamin C
- Where
- Singapore
- Volunteers
- 240 people
- Sponsor
- KK Women's and Children's Hospital
Chronic Postsurgical Pain
CSF Single-cell Sequencing and Proteomics of Chronic Postsurgical Pain in Patients With Lower Limb Fractures
The purpose of this study is to assess the proteomics and transcriptomic differences between pain-free control subjects and patients with chronic postoperative pain through single-cell sequencing technology.
- Trial name
- NCT06126289
- Volunteers
- 20 people
- Sponsor
- Xuzhou Central Hospital
Fracture
Adequacy of Pain Management for Upper Extremity Fracture After Discharge From a Pediatric Emergency Depart
Pain is a common cause for children seeking care in the Emergency Department (ED). Children with orthopedic injuries often require pain control when seeking emergency care.
- Trial name
- NCT01514097
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Surgical Wound Infection
Local Gentamicin Application to Reduce Postoperative Infection Rate
The majority of elderly patients with a displaced fracture of the proximal femur are now treated with a hemiarthroplasty. Prosthetic joint infection is a devastating complication, and the infection rate is high in this group of…
- Trial name
- NCT01287780
- Testing
- Collagen-gentamicin sponge
- Where
- 5 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Oslo University Hospital
Bone Cyst Aneurysmal, Pathological Fracture
Denosumab: A Potential Treatment Option for Aneurysmal Bone Cysts
The efficacy of traditional therapeutic approaches for aneurysmal bone cysts (ABC), such as surgery, embolization, sclerotherapy and radiotherapy, are often compromised for lesions in axial skeletons and adolescents complicated…
- Conditions
- Bone Cyst Aneurysmal, Pathological Fracture, Recurrent Disease, Refractory Tumor
- Trial name
- Deno-ABC (NCT03415477)
- Testing
- Denosumab (Xgeva)
- Volunteers
- 6 people
- Sponsor
- Peking University People's Hospital
Nonunion of Fracture of Tibia (Diagnosis)
Risk Factors for Post-Operative Nonunion of Tibial Shaft Fractures Based on a Path Analysis Model
Tibial shaft fractures is common long tubular fracture that account for about 13.7% of all fractures. And the incidence of nonunion of tibial shaft fracture varied from 1% to 80%.
- Trial name
- NCT03928912
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine