Clinical trials: Patient Care
Critical Illness, Ventilated Patients
Critical Illness After Hematopoietic Cell Transplantation
This is a prospective, multicenter observational trial for patients who develop critical illness after hematopoietic cell transplantation.
- Conditions
- Critical Illness, Ventilated Patients, Hematopoetic Stem Cell Transplantation, Transplant Complication
- Trial name
- CARE-HCT (NCT07328724)
- Where
- 6 sites in China
- Volunteers
- 4,000 people
- Sponsor
- Peking University People's Hospital
COVID-19, Respiratory Failure
Photobiomodulation Therapy Combined With Static Magnetic Field in Patients With COVID-19
Coronavirus disease 2019 (COVID-19) is a disease caused by a novel coronavirus called SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2).
- Trial name
- NCT04386694
- Testing
- Active PBMT/sMF
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Congenital Heart Disease (CHD), Screening Tool
Efficacy Comparison Between Primary Care Physicians' Independent Auscultation and AI-assisted Auscultation for Congenital Heart Disease Screening in Patient-enriched Populations: A Randomized Controlled Trial
In recent years, the application of artificial intelligence (AI) in the healthcare domain has witnessed a significant surge, with deep learning emerging as a potent force in the medical field.
- Conditions
- Congenital Heart Disease (CHD), Screening Tool, Artifical Intelligence, Randomised Controlled Trial
- Trial name
- NCT06791096
- Testing
- AI-assisted auscultation, Independent auscultation
- Where
- 2 sites in China
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Kun Sun
Asthma, Nonadherence, Medication
Symptom-driven ICS/LABA Therapy for Patients With Asthma Non-adherent to Daily Maintenance Inhalers
Inhaler nonadherence is a common problem that has been estimated to account for approximately 60% of all asthma-related hospitalizations.
- Trial name
- NCT05111262
- Testing
- Adherence to symptom driven budesonide/formoterol as compared to adherence to maintenance ICS and symptom-driven SABA
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Asthma in Children, Nonadherence, Medication
Symptom-driven ICS/LABA Therapy for Adolescent Patients With Asthma Non-adherent to Daily Maintenance Inhalers
Inhaler nonadherence is a common problem that has been estimated to account for approximately 60% of all asthma-related hospitalizations.
- Trial name
- NCT05689983
- Testing
- Maintenance ICS and Symptom Driven SABA, Symptom-driven budesonide/formoterol combination
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Washington University School of Medicine
Protective Ventilation
Comparison of Tidal Volume Between Pediatric Anaesthesia and Paediatric Intensive Care Patients
Paediatric anaesthesiology and paediatric intensive care unit data will be retrospectively screened for the data regarding mechanical ventilation.
- Trial name
- TIVAC (NCT03877354)
- Testing
- Data from anaesthesia records for ventilation setting screening, Data from intensive care records for ventilation setting screening
- Where
- Czechia
- Volunteers
- 1,000 people
- Sponsor
- Brno University Hospital
Muscular Dystrophies, Becker Muscular Dystrophy
Evaluation of Muscle miRNA as Biomarkers in Dystrophinopathies
Duchenne muscular dystrophy (DMD) , caused by mutations in the DMD gene, is the most common and most severe progressive dystrophy of the child.
- Conditions
- Muscular Dystrophies, Becker Muscular Dystrophy, Duchenne Muscular Dystrophy
- Trial name
- biodystromirs (NCT02109692)
- Testing
- blood sample
- Where
- France
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cuff Pressure, Mechanical Ventilation
Comparison of Automatic and Manual Endotracheal Tube Cuff Pressure Monitoring in Pediatric Intensive Care Patients
This prospective, randomized controlled cross-over study compares automatic (IntelliCuff®) and manual methods of endotracheal tube cuff pressure (CP) monitoring in pediatric intensive care patients.
- Conditions
- Cuff Pressure, Mechanical Ventilation, Pediatric Intensive Care
- Trial name
- NCT06965400
- Testing
- Automatic Cuff Pressure Control
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dr. Behcet Uz Children's Hospital
Patient Education as Topic, Osteoarthritis
Patient Enablement in Osteoarthritis - a Longitudinal Study on Patient Education Programs in Primary Health Care
The overall purpose is to study quality in patient education by means of the patients' self-rated enablement. Specific aims are: To assess the validity of the patient enablement instrument in relation to self-efficacy and…
- Trial name
- NCT02974036
- Testing
- Patient education for osteoarthritis
- Where
- Sweden
- Volunteers
- 143 people
- Sponsor
- Lund University
Asthma
To Evaluate the Use of ASTHMA IQ in a Primary Care Setting
There is a mounting body of evidence suggesting that there is a large disparity between the development and the actual implementation of guideline-driven asthma care in primary and specialty care practices.
- Trial name
- AIQ (NCT01296477)
- Where
- United States
- Volunteers
- 375 people
- Sponsor
- American Academy of Family Physicians
Dementia, Behavior
Deprescribing Antipsychotics in Long-Term Care
Aggressive behaviours in long-term care (LTC) is a difficult health care issue to manage. One method that has been over-used is the prescription of antipsychotics for the behaviours and psychological symptoms of dementia (BPSD).
- Trial name
- NCT02958800
- Testing
- Intervention
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- McMaster University
High-risk Pregnancy, Hospitalization
LLM-Generated Medical Summaries During Hospitalization to Improve Patient Activation in High-Risk Pregnancies
The goal of this clinical trial is to learn if AI-generated medical summaries help hospitalized pregnant participants better understand and actively participate in their own care.
- Conditions
- High-risk Pregnancy, Hospitalization, Patient Activation, Artificial Intelligence (AI)
- Trial name
- NCT07823517
- Testing
- LLM-Generated Medical Summaries
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Mental Health, Mental Disorders
A Patient-Partnered, Pan-Canadian, Comparative Effectiveness Evaluation of an Acute Pediatric Mental Health and Addiction Care Bundle
The investigators will determine, in an 8-site, hybrid Type 1 cluster randomized effectiveness implementation trial, if an acute mental health care bundle, compared to standard care, improves wellbeing at 30 days in children and…
- Conditions
- Mental Health, Mental Disorders, Pediatrics, Emergency Psychiatric
- Trial name
- NCT04902391
- Testing
- Health Services
- Where
- 8 sites in Canada
- Volunteers
- 6,800 people
- Sponsor
- University of Calgary
Pediatric, Well Child Care
Comparing a Team-Based Approach to Standard Well-Child Visits To Improve Preventive Care Services
Parent-focused Redesign for Encounters, Newborns to Toddlers (PARENT) is a team-based approach to care that utilizes a community health worker in a health educator role ("Parent's Coach") to provide many of the Well-Child Care…
- Trial name
- NCT05852392
- Testing
- Adapted PARENT Model
- Where
- 3 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Human Papilloma Virus, HPV Vaccination
Increasing HPV Vaccination Rates Via Educational Interventions in Schools Located Within Cedars-Sinai Catchment Areas
Infections with human papillomavirus (HPV) can cause cancer of the cervix, vagina, anus, throat, mouth, and penis. Prevention of these HPV-related cancers could be achieved by immunization with the nonavalent…
- Conditions
- Human Papilloma Virus, HPV Vaccination, Health Education
- Trial name
- NCT03953911
- Testing
- Mobile Clinic, Educational Sessions for Parents
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Venous Thromboembolism (VTE), Pulmonary Embolism
Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)
This is an event driven Phase 3, prospective, randomized, open-label, blinded endpoint evaluation (PROBE) parallel group study in subjects with confirmed VTE.
- Conditions
- Venous Thromboembolism (VTE), Pulmonary Embolism, Deep Vein Thrombosis (DVT)
- Trial name
- NCT02798471
- Testing
- Edoxaban, Standard of Care
- Where
- 140 sites in United States, Argentina and 32 more
- Volunteers
- 290 people
- Sponsor
- Daiichi Sankyo
HIV, HIV Infections
Evaluation of Conditional Cash Transfers to Increase Retention in PMTCT Services in Akwa Ibom State, Nigeria
A randomized controlled trial will be conducted to assess the effectiveness of conditional cash transfers (CCTs) at increasing retention in prevention of mother-to-child transmission (PMTCT) services specifically, in relation to…
- Conditions
- HIV, HIV Infections, Pregnancy, Infant, Newborn, Diseases
- Trial name
- NCT02447159
- Testing
- Conditional Cash Transfers
- Where
- 3 sites in Nigeria
- Volunteers
- 554 people
- Sponsor
- University of California, San Francisco
Asthma
Effect of a Mobile App on Improving Asthma Control in Patients With Persistent Asthma
mINSPIRERS_RCT aims to assess the magnitude of the effect of a mobile app for improving asthma control in adolescents and adults with persistent asthma, followed at primary and secondary care in Portugal.
- Trial name
- mINSPIRERS_RCT (NCT05129527)
- Testing
- InspirerMundi app, Usual care
- Where
- Portugal
- Volunteers
- 124 people
- Sponsor
- Universidade do Porto
HIV
Comparing the Effectiveness of Two Alcohol+Adherence Interventions for HIV+ Youth
Alcohol use among persons with HIV exacerbates health problems and accelerates HIV disease progression. Antiretroviral therapy (ART) is the single most important treatment for people living with HIV.
- Trial name
- NCT01969461
- Testing
- Motivational Enhancement Therapy (MET)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Wayne State University
Asthma
Pediatric Study to Evaluate Treatment of Persistent Moderate or Severe Asthma With the Association Fluticasone 250 mcg/Dose and Salmeterol 50 mcg/Dose - ADERE PROJECT
Prospective, parallel-group, randomized study to evaluate the compliance to the treatment of children aged between 6 and 14 years old with persistent moderate or severe asthma, receiving the association Fluticasone 250 mcg/dose…
- Trial name
- ADERE (Ped) (NCT01476059)
- Testing
- Telephone follow-up, No telephone follow-up
- Volunteers
- 472 people
- Sponsor
- GlaxoSmithKline
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