Clinical trials: Patient Cataract
Cataract Extraction, Fasting
Preoperative Fasting for Ambulatory Cataract Surgery: The PRACTICE Study
The current standard for cataract surgery is phacoemulsification with intraocular lens (IOL) implantation. In this procedure, topical anesthesia has become favoured over local anesthetic blocks due to potential serious…
- Conditions
- Cataract Extraction, Fasting, Aspiration Pneumonitis
- Trial name
- PRACTICE (NCT03828500)
- Testing
- Assistant-encouraged fasting up to ASA/CAS guideline limits
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Toronto
Glaucoma, Cataract
Effect of Elevated Intraocular Pressure in Glaucoma Patients During Femtolaser Cataract Surgery
The use of the femtosecond laser causes an increase in the intraocular pressure (IOP) between 100 mm Hg and 200 mm Hg for a period of about 80 seconds (suction phase).
- Trial name
- FEMTOHTO (NCT02835482)
- Testing
- Femtolaser surgery, Phacoemulsification
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Cataract
Developmental Profile of Ocular Refraction in Patients With Congenital Cataract
The purpose of prospective cohort study is to describe the developmental profile of refraction change in a large cohort of Chinese CC patients.
- Trial name
- NCT02761850
- Where
- China
- Volunteers
- 1,164 people
- Sponsor
- Sun Yat-sen University
Patient Cataract
Propofol Versus Sevoflurane Anesthesia on the Intraocular Pressure and Hemodynamics in Patient Undergoing Cyclophotocoagulation
we use two different technique of anaesthesia for anaesthesia of patient undergoining CPC operation (20 each) were comparable with regard to demographic data and hemodynamic variables, IOP.
- Trial name
- cyclophotocoag (NCT07445672)
- Testing
- Propofol and Fentanyl administration, Sevoflurane and fentanyl administration
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Cerebra-retinal Angiopathy
COL4A1 Gene Related Cerebra-retinal Angiopathy
This prospective multicenter cohort study aims to define the clinical, radiological and mutational spectrum of the disease related to COL4A1 gene.
- Trial name
- COL4A1 (NCT01097564)
- Testing
- COL4A1 genetic testing
- Where
- France
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cataracts
A Prospective Study Comparing Visual Outcomes and Patient Satisfaction Following Implantation of the Clareon PanOptix Versus Tecnis Odyssey IOL in Patients Undergoing Cataract Surgery.
To evaluate visual outcomes and patient satisfaction following bilateral implantation of the Clareon PanOptix versus Tecnis Odyssey IOL in patients undergoing cataract surgery
- Trial name
- NCT07768475
- Testing
- Intraocular Lens Implant
- Where
- 4 sites in United States
- Volunteers
- 266 people
- Sponsor
- Nvision Laser Eye Centers
Endophthalmitis
OTX-14-002: Device Exposure Registry
The objective of the study is to collect post-approval data relative to the incidence of endophthalmitis for cataract surgery patients treated with the FDA-approved ReSure Sealant when used by a broad group of physicians under…
- Trial name
- NCT02309736
- Testing
- ReSure Sealant
- Sponsor
- Ocular Therapeutix, Inc.
Cataract
Safety of NGOIS Compared to BSS Plus in Pediatric Patients
To evaluate the Safety of Next Generation Ophthalmic Irrigating Solution compared to BSS Plus for use during cataract surgery in Pediatric patients.
- Trial name
- NCT00346528
- Testing
- Next Generation Ophthalmic Irrigating Solution (NGOIS), BSS Plus
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Alcon Research
Correction Vision Surgery, Cataract Surgery
Clinical Outcomes of Bilateral Clareon Vivity in Post-Refractive Patients
Millions of people have undergone laser vision correction surgery and are motivated to continue with spectacle independence as they develop presbyopia (gradual loss of your eyes' ability to focus on nearby objects)and cataract.
- Trial name
- NCT06924944
- Testing
- cataract surgery
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Utah Eye Centers
Cataract Senile
Biaxial Microincision Cataract Surgery Technique
To analyze and compare visual results, keratometry, SIA and HOAs outcomes of biaxial microincision cataract surgery in elderly population, including diabetic and non-diabetic patients.
- Trial name
- BiMICS14vs18 (NCT03793101)
- Testing
- BiMICS
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eyemed Centrum Okulistyczne
Cataract in Child
Aspheric Monofocal Intraocular Lens in Pediatric Patients
To evaluate the performance a new aspheric monofocal intraocular lens (IOL) with higher order aspheric optic for far, intermediate, and near vision, in pediatric patients after monolateral cataract surgery.
- Trial name
- NCT06153745
- Testing
- Tecnis Eyhance ICB00 intraocular lens (Johnson&Johnson Vision, Santa Ana, California USA)
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Luca Buzzonetti
MCS vs ReLACS, Pain Perception Postoperatively First Eye vs Second Eye
A Comparison of Patient Perceptions Undergoing Manual Cataract Surgery (MCS) vs Refractive Laser-assisted Cataract Surgery (ReLACS) in First and Second Eyes
The focus of this study is to assess how pain can be mitigated for patients undergoing cataract surgery through the early application of anesthesia prior to the surgery as compared to the standard timing, and by using the ReLACS…
- Conditions
- MCS vs ReLACS, Pain Perception Postoperatively First Eye vs Second Eye, Early Anesthesia vs Standard Anesthesia
- Trial name
- NCT04623229
- Testing
- MCS, ReLACS Early, ReLACS Standard
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Uptown Eye Specialists
High Myopia, Low Intraocular Pressure
Improved Operation of Low Intraocular Pressure in Phacoemulsification for Patients With High Myopia Complicated With Cataract
Approximately 60 participants at Eye Hospital of Wenzhou Medical University during October,2021 to January 2022 will be enroll in the investigators' study.
- Trial name
- NCT05201677
- Testing
- Supplement of perfusion fluid through the subiris suspensory ligament space from the lateral incision
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yune Zhao
Cataract, Sleep
The Effect of Cataract Surgery on Sleep Quality
A cataract is a clouding of the crystalline lens inside the eye, which leads to a decrease in vision. It is the most prevalent, treatable cause of visual impairment and blindness in the world.
- Trial name
- NCT02593669
- Testing
- Phacomulsification lens removal cataract surgery with neutral Intraocular lens(IOL) implantation, Phacomulsification lens removal cataract surgery with blue-blocking Intraocular lens(IOL) implantation, Subconjunctival dexamethasone and general anesthesia
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Sun Yat-sen University
Cataract
Visual Quality of Cataract Patients with High Myopia After Implantation of Different Intraocular Lenses
This prospective study aims to compare the visual outcomes following the implantation of two different types of multifocal intraocular lenses (IOLs) in highly myopic patients.
- Trial name
- NCT06892470
- Testing
- No intervention
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Wenzhou Medical University
Cataract
Effect of the Timing of Cataract Surgery on Complications in Patients With Bilateral Congenital Cataracts
Congenital cataract is an important treatable cause of visual handicap in childhood throughout the world. Successful management of childhood cataract is dependent on individualized treatment strategies and rigorous postoperative…
- Trial name
- NCT02581046
- Testing
- Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 3month of the patients, Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 6 month of the patients, Subconjunctival dexamethasone and general anesthesia
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Sun Yat-sen University
Congenital Cataract Polar Posterior
Visual Function in Pediatric Patients With Posterior Lens Opacities
Prognostic factors determining visual outcomes in patients with posterior polar cataracts and posterior lenticonus are largely unknown.
- Trial name
- NCT05207007
- Testing
- Phacomulsification lens removal cataract surgery with Intraocular lens(IOL) implantation
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Sun Yat-sen University
Open Angle Glaucoma and Cataract
RCT to Investigate if Prostaglandin Analogue Drops Increase the Risk of Cystoid Macular Oedema After Cataract Surgery.
Post-operative cystoid macular oedema (CMO) is a common complication causing visual loss following routine cataract surgery. This complication is more prevalent in eyes with excessive inflammation as they heal from surgery.
- Trial name
- CMO (NCT03292796)
- Testing
- Prostaglandins
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Julie Dawson
Cataract, Presbyopia
Prospective Clinical Trial of Unilateral or Bilateral Implantation of TecnisSymfony IOL in Cataract Patients With Presbyopia
This is to evaluate the satisfaction of patient and physician about short-distance, medium-distance, long-distance postoperative vision and eyeglass dependence, glare, and visual acuity after insertion of the TECNIS® Symfony or…
- Trial name
- NCT03501654
- Testing
- TecnisSymfony®
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Congenital Cataract
Reduction of Corneal Astigmatism With Toric Intraocular Lens Implantation in Congenital Cataract
This study was conducted to evaluate changes of reduction of corneal astigmatism with toric intraocular lens(IOL) in congenital cataract.
- Trial name
- NCT02040129
- Testing
- Acrysof Toric IOL
- Where
- South Korea
- Volunteers
- 4 people
- Sponsor
- Kyungpook National University Hospital