Clinical trials: Patient Controlled Analgesia
Obstructive Sleep Apnea Syndrome
Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy
The study will evaluate the post-operative morphine-sparing effect, pain reduction, and side effects of a continuous ketamine infusion after tonsillectomy in pediatric patients.
- Trial name
- KOSATA (NCT02425202)
- Testing
- Ketamine, Saline infusion
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Chronic Pain, Cancer
Immersive Multimedia as an Adjunctive Measure for Pain Control in Cancer Patients
This study seeks to explore the efficacy of immersive multimedia experiences as a practical adjunctive therapeutic intervention in the self-management of the chronic pain associated with cancer patients.
- Trial name
- NCT02995434
- Testing
- Virtual Reality Headset, 2D PC
- Where
- 3 sites in Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anesthesia, Local
Comparing Analgesic Effects of Caudal and Erector Spinae Plane Blocks in Pediatrics Undergoing Upper Abdominal Surgery
Upper abdominal surgeries are painful and pediatric patients who undergo these operations require effective postoperative pain control.
- Trial name
- NCT04204343
- Testing
- Bupivacaine 0.7 ml/kg, Bupivacaine 0.5 ml/kg
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
CHD - Congenital Heart Disease
Bilateral Ultrasound Guided Superficial Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block
Group (A): This group will receive fentanyl infusion at a dose of (0.5μg/kg/h) all through the whole operation plus ultrasound guided bilateral superficial parasternal intercostal Plane block which will be done by injecting…
- Trial name
- NCT06958120
- Testing
- superficial parasternal intercostal Plane block, Erecto spinea plane block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Labour Pain, Satisfaction
Remifentanil as Intravenous Patient-controlled Analgesia (IVPCA) During Labour
Remifentanil is a ultra short-acting synthetic opioid. It is rapidly metabolized by non-specific blood and tissue esterases. We wanted to investigate the efficacy and safety of remifentanil used as analgesia during labour.
- Conditions
- Labour Pain, Satisfaction, Adverse Effects
- Trial name
- NCT00202722
- Testing
- Remifentanil
- Where
- Norway
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Sickle Cell Disease
THE IMPROVE TRIAL: Improving Pain Management and Outcomes With Various Strategies of Patient-Controlled Analgesia (PCA)
Patient-Controlled Analgesia (PCA) means that the patient is in control of his/her pain medicine. In this study two (2) different treatment plans of Patient-Controlled Analgesia will be used to treat people with sickle cell…
- Trial name
- IMPROVE (NCT00999245)
- Testing
- High Demand / Low Infusion, PCA Dosing Plan
- Where
- 28 sites in United States
- Volunteers
- 38 people
- Sponsor
- Carelon Research
Scoliosis; Adolescence, Pain After Surgery
Tegileridine for Postoperative Pain After Adolescent Scoliosis Surgery
The goal of this clinical trial is to see if a new pain medicine called Tegileridine is at least as effective as morphine (the standard treatment) for pain relief after spinal surgery in teenagers with scoliosis.
- Conditions
- Scoliosis; Adolescence, Pain After Surgery, Analgesia, Patient-controlled
- Trial name
- NCT07229495
- Testing
- Tegileridine, morphine
- Where
- 6 sites in China
- Volunteers
- 171 people
- Sponsor
- Peking Union Medical College Hospital
Axillary Brachial Plexus Block
The Efficacy of Intravenous Dexamethasone on the Duration of Analgesia of Ultrasound Guided Axillary Brachial Plexus Block in Pediatric Patients Undergoing Below Elbow Orthopaedic Surgeries
Postoperative pain is a common manifestation in orthopedic patients, mainly due to intraoperative tissue damage , inadequate intraoperative pain assessment and management.
- Trial name
- NCT05466500
- Testing
- Ultrasound guided axillary block with intravenous dexamethasone, Ultrasound guided axillary block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Pain, Postoperative
Efficacy Study of Rectus Sheath Block to Control Postoperative Pain
The aim of this study is to evaluate the effect of the ultrasound guided rectus sheath block (RSB) on both intraoperative sevoflurane consumption and postoperative analgesia.
- Trial name
- UGRSB (NCT02115087)
- Testing
- ultrasound guided rectus sheath block, Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cukurova University
Pancreatitis, Chronic
Surgical Outcome and Differences on Histopathology in Patients With Alcoholic & Non Alcoholic Chronic Pancreatitis
Numerous treatment modalities have been proposed to treat pain in alcoholic and non-alcoholic chronic pancreatitis such as analgesic medication, inhibition of gastric acid production, enzyme substitution, somatostatin analogues…
- Trial name
- NCT02048267
- Testing
- Frey's procedure/Pylorus preserving pancreatoduodenectomy
- Where
- India
- Volunteers
- 24 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cancer Pediatric
Ultrasound-guided Selective Supraclavicular Nerve Block for Postoperative Pain Control in Pediatric Patients.
This prospective randomized controlled trial aims to investigate the effect of ultrasound-guided selective supraclavicular nerve block on pain control after Hickman catheter, chemoport, or Perm cath insertion in children.
- Trial name
- NCT05015907
- Testing
- Ropivacaine, Control (without intervention)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Postoperative Pain
Patient Controlled Analgesia Pump Cues on Patient Satisfaction
To examine whether providing patients with a cue to the availability of pain medication affects patient satisfaction, patient anxiety, PCA efficacy, and safety.
- Trial name
- PCA Cues (NCT02456909)
- Testing
- Patient-Controlled Analgesia pump with Cues, Patient-Controlled Analgesia pump without Cues, Morphine
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Medical College of Wisconsin
Pain
Assessing the Efficacy of Virtual Reality Analgesia (VRA) in Pediatric Patients for Pain Control
To evaluate the efficacy of virtual reality analgesia (VRA) for pediatric patients undergoing Botulinum toxin injections (BTI) for spasticity management.
- Trial name
- PEDSPAINVR (NCT03480724)
- Testing
- Google Cardboard VRA, Oculus Rift VRA
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Montefiore Medical Center
Staphylococcus Aureus Bacterial Contamination
Investigation of Antibacterial Effect of Levobupivacaine on Staphylococcus Aureus
This experimental in vitro study aimed to investigate the antibacterial effect of levobupivacaine on Staphylococcus aureus in a patient-controlled analgesia (PCA) model at concentrations commonly used for postoperative pain…
- Trial name
- NCT07285759
- Testing
- Levobupivacaine, Fentanyl, Saline
- Volunteers
- 40 people
- Sponsor
- Dokuz Eylul University
Lung Transplantation, Pain Management
The Effect of Bupivacaine Liposomes on Postoperative Pain in Lung Transplant Patients After Intercostal Nerve Block: a Randomized Controlled Study
The goal of this clinical trial is to evaluate the efficacy and safety of liposomal bupivacaine for postoperative analgesia in adult patients undergoing lung transplantation.
- Conditions
- Lung Transplantation, Pain Management, Liposomal Bupivacaine
- Trial name
- NCT07641647
- Testing
- LB/BH intercostal nerve block, BH intercostal nerve block
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Postoperative Pain, Opioid Use
SZMN Blocks for Pain Control in Pediatric Patients Undergoing T&A
The suprazygomatic maxillary nerve (SZMN) block is a well-established, safe and effective regional technique for pain management following cleft palate procedures, however, have not been studied for patients undergoing…
- Trial name
- SZMN (NCT04797559)
- Testing
- SZMN Block
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Opioid Use, Pain, Postoperative
ESP Block in Pediatric Patients for Postoperative Analgesia
Pediatric cardiac surgery is associated with moderate to severe postoperative pain that is related to median sternotomy. In a fast-track protocol, used in modern-day cardiac surgical care, early extubation may be facilitated by…
- Conditions
- Opioid Use, Pain, Postoperative, Quality of Life
- Trial name
- ESP1 (NCT03627897)
- Testing
- Bupivacain, saline
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cukurova University
ACL Repair, Meniscectomy
Efficacy Study of Continuous Intraarticular Infusion in Patients Undergoing Arthroscopic Knee and Shoulder Operations
The aim of this study is to determine whether the continuous intraarticular infusion of local anesthetics in the postoperative period can improve analgesia and patients satisfaction after knee and shoulder arthroscopy.
- Conditions
- ACL Repair, Meniscectomy, Bankart Repair
- Trial name
- NCT00314457
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Children's Hospital of Philadelphia
Post Operative Pain
Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay
The purpose of this study is to compare, the safety, efficacy and level of parent and nurse satisfaction with three methods of opioid administration post-operatively in children (4-18 years of age) with developmental delay.
- Trial name
- PNCA (NCT00743730)
- Testing
- Pain and standard side effect management for PNCA with basal method., Pain and standard side effect management with PNCA without basal, Pain and standard side effect management with IV on an as needed basis method.
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Medical College of Wisconsin
Ureteroneocystostomy
The Effect of Intravenous (IV) Patient Controlled Analgesic (PCA) With Ketorolac or Fentanyl Combined With Caudal Block for Postoperative Analgesia in Small Children Undergoing Intravesical Ureteroneocystostomy
The effect of IV PCA with ketorolac or fentanyl combined with caudal block for postoperative analgesia in small children undergoing intravesical ureteroneocystostomy.
- Trial name
- NCT01081535
- Testing
- ketorolac, fentanyl
- Volunteers
- 50 people
- Sponsor
- Yonsei University