Clinical trials: Patient Reported Outcome (PRO)
Deformity of Limb
Study of Infantile Lower Limb Malformations and Deformities
The skeletal defects of the lower limbs in pediatric age encompass various congenital and acquired conditions that alter bone structure.
- Trial name
- REMEDIA-I (NCT06519175)
- Testing
- Conservative treatment, Single or multi-stage surgery, Amputation
- Where
- 7 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Istituto Ortopedico Rizzoli
Breast Augmentation
Long-Term Effectiveness of the Motiva Implants® Round and Round Ergonomix
Post-marketing surveillance study to demonstrate the silent rupture rate and satisfaction of patients who underwent a primary and revision breast augmentation surgery with Motiva Implants®, 3 to 10 years before enrollment.
- Trial name
- MIRO (NCT05449587)
- Testing
- MRI and PRO
- Where
- 2 sites in Costa Rica
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Motiva USA LLC
Oncology, Quality of Life
Measuring Health Related Quality of Life in AYAs
AIM1a: AYAs with cancer experience many challenges that impact their health-related quality of life (HRQOL) but few measures adequately capture AYAs' HRQOL in valid and reliable ways.
- Trial name
- PROMIS AYA (NCT03482778)
- Where
- 3 sites in United States
- Volunteers
- 165 people
- Sponsor
- Wake Forest University Health Sciences
Total Knee Arthroplasty, Arthroplasty of Knee
Navio With Total Knee Arthroplasty
The purpose of this study is to demonstrate superior accuracy with the Navio ™ Robotic-assisted Surgical System in achieving desired post-operative mechanical alignment, compared to TKA procedures using standard instruments.
- Trial name
- NCT03317834
- Testing
- Navio ™ Robotic-assisted Surgical System
- Where
- 6 sites in United States
- Volunteers
- 122 people
- Sponsor
- Smith & Nephew, Inc.
Type1diabetes, Covid19
Covid-19 Pandemic: Patients' Experience in T1D
Given the current situation with COVID-19 declared pandemic on March 11, 2020 and the requirement for physical distancing and to limit social interactions, and for some, to quarantine, the investigators will survey patients…
- Trial name
- NCT04384471
- Testing
- Online survey
- Where
- Canada
- Volunteers
- 384 people
- Sponsor
- McGill University
Prematurity; Extreme, Prematurity; Decision Support
Health-Related Quality-of-Life and Household Financial and Wellbeing Impacts of Prematurity and Necrotising Enterocolitis (NEC).
PREM-IMPACT is a UK-based observational study exploring how caring for a very premature baby-particularly one affected by necrotising enterocolitis (NEC)-impacts families over the first year after hospital discharge.
- Conditions
- Prematurity; Extreme, Prematurity; Decision Support, Necrotising Enterocolitis, Preterm
- Trial name
- PREM-IMPACT (NCT07192393)
- Where
- 7 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- Imperial College London
Lung Transplantation, Respiratory Failure
Prognosis of Lung Transplant Candidates
The purposes of the study are (1) to analyze the baseline patient characteristics cross-sectionally, (2) to analyze the prognosis and its predictive factors and (3) to examine the longitudinal clinical course in the lung…
- Trial name
- NCT00905463
- Testing
- Lung transplantation
- Where
- 4 sites in Japan
- Volunteers
- 272 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Deep Bite Malocclusion
Bonded Bite Turbos Were Bonded to Palatal Surfaces of Maxillary Incisors for Sixty Patients With Anterior Deep Overbite to Check Acceptance Rate of Patients to These Bite Turbos.
Background: Bonded composite bite turbos are an efficient tool in the treatment of deep bite malocclusion. Patient satisfaction with orthodontic appliances has been correlated with treatment success.
- Trial name
- ABT-SAT (NCT07143916)
- Testing
- bonded anterior bite turbos
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Metatarsus Adductus, Hallux Valgus
Outcomes Following Combined Adductoplasty™ and Lapiplasty® (MTA3D)
Prospective, multicenter, unblinded study to evaluate outcomes of the Adductoplasty™ Procedure in combination with the Lapiplasty® Procedure for patients in need of metatarsus adductus and hallux valgus correction.
- Trial name
- MTA3D (NCT05587569)
- Testing
- Treatment of metatarsus adductus and hallux valgus with the Adductoplasty™ Procedure in combination with the Lapiplasty® Procedure
- Where
- 9 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Treace Medical Concepts, Inc.
Proximal Humerus Fracture
Outcome After Plate Osteosynthesis of Proximal Humerus Fractures Using Continous Passive Motioning Therapy
Patients suffering from a proximal humerus fracture treated with plate osteosynthesis will receive either regular aftercare (physiotherapy) or aftercare assisted with continous passive motion (physiotherapy + CPM).
- Trial name
- NCT05952622
- Testing
- Continuous passive motion therapy
- Where
- Germany
- Volunteers
- 103 people
- Sponsor
- Technische Universität Dresden
Sickle Cell Disease, Sickle Cell Hemoglobin C
Home-based Assessment of PRO Measures in SCD Using A Smartphone App Platform: A Feasibility Study
The overarching goal of this proposal is to identify modifiable behavioral strategies based on patient-reported outcomes (PROs) and health-related quality of life (HRQOL) that will improve hydroxyurea (HU) adherence among…
- Conditions
- Sickle Cell Disease, Sickle Cell Hemoglobin C, Sickle Beta Zero Thalassemia, Sickle B+ Thalassemia
- Trial name
- NCT04678037
- Testing
- PROs assessment using sickle cell disease mobile app (SCD-app)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Bariatric Surgery, Metabolic Surgery
Comparative Effectiveness of Metabolic and Bariatric Surgery With PROMs
This long-term, nationwide observational data collection repository will obtain patient-reported outcomes from metabolic and bariatric surgery patients.
- Conditions
- Bariatric Surgery, Metabolic Surgery, Weight Reduction
- Trial name
- MBSAQIP-PROM (NCT02749305)
- Testing
- Collection of patient-reported outcome measures
- Where
- United States
- Volunteers
- 11,146 people
- Sponsor
- Massachusetts General Hospital
Tumor, Malignancy
Validation Study of Pediatric Patient-Reported Outcomes
Survivors of childhood cancer often suffer treatment-related toxicities, including chronic health conditions, high symptom burden and emotional distress, and decremented functional status and quality of life.
- Trial name
- NCT03229837
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- St. Jude Children's Research Hospital
Asthma in Children
Personalised Outcomes in Children With Recurrent Wheeze
This project aims to develop a PROM for preschool children with recurrent wheeze. Nearly one third of children will have at least one episode of wheeze in the first five years of life.
- Trial name
- NCT03858010
- Testing
- Wheeze and me questionnaire
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Type1diabetes, Pediatric ALL
CloudCare in the Treatment of Type 1 Diabetes in Pediatrics
This prospective cohort study aims to estimate the effect of the CloudCare application in daily practice on treatment satisfaction and emotional burden for pediatric patients and their parents/caregivers, patients' glycemic…
- Trial name
- NCT06018324
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- Diabeter Nederland BV
Hallux Valgus Deformity, Hallux Valgus (Bunion) Resection
Fourth Generation Percutaneous Transverse Osteotomies for Hallux Valgus
The goal of this observational study is to learn if percutaneous transverse osteotomies for hallux valgus deformity are safe and effective. The main questions it aims to answer are: 1.
- Conditions
- Hallux Valgus Deformity, Hallux Valgus (Bunion) Resection, Hallux Valgus Surgery, Hallux Deformity
- Trial name
- NCT06625229
- Where
- Australia
- Volunteers
- 483 people
- Sponsor
- Orthopaedic and Arthritis Specialist Centre
Lower Lip Tissue Loss, Cancer
Functional and Aesthetic Outcomes Following Lower Lip Reconstruction
This retrospective study, aims to evaluate the functional and aesthetic results of lower lip reconstructions, incorporating both patient experiences and the analysis of physicians and surgeons working on facial issues (plastic…
- Trial name
- REFEPLI (NCT07298070)
- Testing
- Patient-Reported Outcome Questionnaire (post-operative)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hôpital NOVO
Cruciate Ligament Rupture
Reconstruction of the Anterior Cruciate Ligament(ACL-R) in the 30+-Year Old Assessed by Patient Reported Outcome Measures(PRO) Using the Nationwide Danish Knee Ligament Reconstruction Registry
The purpose of the study is to evaluate the efficacy of primary ACL-R in patients 30 years of age or older using PRO. The PRO used are Knee Osteoarthritis Outcome Score(KOOS) and Tegner score.
- Trial name
- NCT04592367
- Testing
- Patient age at time of procedure of reconstruction of ACL
- Where
- Denmark
- Volunteers
- 30,487 people
- Sponsor
- Region Zealand
Gingivitis, Healthy Adult
Comparative Evaluation of the Anti-Plaque and Anti-Gingivitis Effects of Nanobiofusion Gingival Gel (NBF), Placebo Gel, and Commercial Toothpaste
The goal of this clinical trial is to learn if Nanibiofusion Gingival Gel (NBF) is able to reduce dental plaque and gum inflammation in adults.
- Trial name
- NCT07850232
- Testing
- Nano Bio-Fusion (NBF) Gingival Gel, Commercial fluoride toothpaste
- Where
- Jordan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Cerebral Palsy
Long-Term Outcomes of Hip Interventions for Children With Cerebral Palsy
Children with severe cerebral palsy (CP) are at high risk for progressive hip displacement, associated with pain and contractures interfering with many aspects of care, comfort and quality of life.
- Trial name
- CHOP II (NCT04792606)
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- The Hospital for Sick Children