Clinical trials: Patients After Cardiac Surgery
Sternotomy Closure,Open Heart Surgery
Comparison Between Interlocking Multi-twisted Wires and Eight Figure of Sternum Closure
Comparison between interlocking multi-twisted wires and Eight figure of sternum closure post open heart surgery in egptian patients
- Trial name
- NCT03343990
- Testing
- Interlocking multi-twisted wires in sternal closure, Eight Figure techniqe in sternal closure
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
DiGeorge Syndrome, Congenital Heart Defects
Infection in DiGeorge Following CHD Surgery
We propose a retrospective review of patients with DiGeorge syndrome having undergone cardiac surgery to evaluate the incidence of blood stream and/or surgical site infection.
- Trial name
- NCT00278005
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Children's Healthcare of Atlanta
Right Ventricular Dysfunction
Evaluation of Right Ventricular Function Post Mitral Valve Operations
We aim to determine the function of Right ventricle post mitral valve surgeries in patients with pulmonary hypertension using transthoracic echocardiography3- and 6-months post-operatively to detect the effect of mitral valve…
- Trial name
- NCT05620992
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Congenital Heart Disease
Relationship of Brain Natriuretic Peptide (BNP) Levels to Cardiac Diagnosis, Operation Performed, Post-operative Course and Outcome
The purpose of this study is to assess brain natriuretic peptide levels to evaluate the relationship of those levels with the diagnosis of congenital cardiac disease, operation performed, post-operative course, and outcome.
- Trial name
- NCT00238810
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Healthcare of Atlanta
Gradient Between Radial and Central Aortic Pressure After Cardiopulmonary Bypass
Evaluation of Aortic-Radial Blood Pressure Gradient in Pediatric Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
Invasive blood pressure monitoring is essential during heart surgery. Usually, doctors measure blood pressure using a small tube (a catheter) placed in an artery, typically in the wrist or arm.
- Trial name
- GARP (NCT07857811)
- Testing
- Placement of a pressure transducer at the accessory port of the CPB arterial cannula
- Where
- 2 sites in Chile
- Volunteers
- 100 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Mechanical Complication of Coronary Artery Bypass Graft, Respiratory Depression
Effects of Osteopathic Treatment on Pulmonary Function After Coronary Artery Bypass Graft Surgery
The purpose of this study is to determine the short and long term effects of osteopathic treatment on pulmonary function, pain and quality of life in patients after coronary artery bypass graft (CABG) surgery.
- Conditions
- Mechanical Complication of Coronary Artery Bypass Graft, Respiratory Depression, Pain, Quality of Life
- Trial name
- OSTinCARE (NCT01714791)
- Testing
- Usual care, Osteopathic treatment
- Where
- Belgium
- Volunteers
- 112 people
- Sponsor
- Hartcentrum Hasselt
Congenital Heart Surgery, Congenital Heart Disease in Children
Blood Based Assessment of sST2, Taken During and After Surgery, for Pediatric Patients With Heart Defects to Predict Heart Failure.
Patients younger than 18 scheduled for congenital heart surgery will be assessed during and post-operatively as well as at the first follow-up after 9-12 month for the novel biomarker sST2.
- Conditions
- Congenital Heart Surgery, Congenital Heart Disease in Children, Fontan Physiology
- Trial name
- NCT07029230
- Where
- Switzerland
- Volunteers
- 225 people
- Sponsor
- Martin Schweiger
Post-cardiac Surgery, Hyperlactatemia
Lactate Acidosis in Postoperative Hearts
This is a single-center, observational study. Investigators aim to characterize the metabolism of lactate in children over the first forty-eight hours following cardiac surgery. Blood samples will be obtained up to 12 timepoints.
- Trial name
- NCT03025659
- Testing
- Pyruvate levels
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Florida
Respiratory Failure, Shock
Comparing Post Cardiac Surgery Outcomes in ESRD Patient's With Early Dialysis Versus Standard Care
End-stage renal disease (ESRD) is an important risk factor for coronary and valvular cardiac disease leading to cardiac surgery.
- Conditions
- Respiratory Failure, Shock, Coagulopathy
- Trial name
- NCT04705701
- Testing
- Hemodialysis
- Sponsor
- Northwell Health
Pulmonary Hypertension
Iloprost-Study: Comparison of Nitric Oxide to Iloprost (Ventavis) for Treatment of Pulmonary Hypertension in Children After Cardiopulmonary Bypass Surgery
Inhaled nitrous oxide (iNO) will be compared to aerosolized iloprost (ILO) in pediatric patients after cardiac surgery with pulmonary hypertension.
- Trial name
- NCT00235521
- Testing
- aerosolized iloprost
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Heidelberg University
Surgical Patients
Heart Rate Changes With Propofol
This is a prospective pilot study to quantify the changes in heart rate when propofol is administered after inhalational anesthesia induction.
- Trial name
- NCT01355432
- Testing
- Observation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nationwide Children's Hospital
Patients With Coronary Artery Disease Scheduled for by Pass Surgery
Atrial Fibrillation and By-pass Surgery
The aim of the study is to evaluate whether combined therapy with beta-blocker, amiodarone and statine is better than beta-blocker alone for the prevention of atrial fibrillation after coronary by-pass surgery.
- Trial name
- NCT01955759
- Testing
- Amiodarone tab 200 mg x 3, rosuvastatin 20 mg tab x1, beta blockers Bisoprolol in adjusted dose
- Where
- Bosnia and Herzegovina
- Volunteers
- 260 people
- Sponsor
- Heart Center BH Tuzla
Post Cardiac Surgery
Minimal Volume for Fluid Challenge in Post-operative Patients
This study evaluate the effect of different doses of crystalloids on the changes on cardiac output (CO) and on the proportion of responders and non-responders and aims to determine the minimal volume required to increase the mean…
- Trial name
- NCT02569008
- Testing
- Fluid challenge with Compound Sodium Lactate
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- St George's, University of London
Heart Defects, Congenital, Intensive Care Units, Pediatric
High-Flow Nasal Cannula vs. NIV After Extubation in Children Undergoing Heart Surgery
High-Flow Nasal Cannula vs. NIV After Extubation in Children Undergoing Heart Surgery
- Conditions
- Heart Defects, Congenital, Intensive Care Units, Pediatric, Respiration, Artificial, Extubation
- Trial name
- NCT07059689
- Testing
- High Flow Nasal Cannula (HFNC), Non-Invasive Ventilation (NIV)
- Where
- Indonesia
- Volunteers
- 114 people
- Sponsor
- Universitas Indonesia
Congenital Heart Disease, Sepsis
Pro-Calcitonin Levels Following Pediatric Cardiac Surgery
First, we, the researchers, hope to find out the PCT response to heart surgery in children by taking blood before surgery and each day for four days after surgery.
- Conditions
- Congenital Heart Disease, Sepsis, Infection
- Trial name
- NCT00284570
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Emory University
Coronary Artery Bypass Surgery
CD0104 VEST II Post Marketing Surveillance Study
This study is designed to collect post market data on use of the VEST, particularly on saphenous vein grafts to the right territory of the heart.
- Trial name
- VEST II (NCT02332330)
- Testing
- VEST
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 30 people
- Sponsor
- Vascular Graft Solutions Ltd.
Aortic Coarctation, Retrospective Studies
Prevalence and Risk Factors for Hypertension and Recoarctation in Patients Operated for Aortic Coarctation
Multicenter Retrospective Study Over a 14-Year Period From 2010 to 2024
- Conditions
- Aortic Coarctation, Retrospective Studies, Cohort Studies, Hypertension
- Trial name
- PRECOHA (NCT07499609)
- Where
- France
- Volunteers
- 901 people
- Sponsor
- Institut Saint Pierre
Cardiovascular Disease, Aortic Valve Stenosis
Evaluating the Risk of Cognitive Impairment After Surgical and Transcatheter Aortic Valve Replacement
The investigators are conducting a pilot study to compare cognitive outcomes among Veterans with severe aortic valve stenosis who are scheduled to undergo either aortic valve replacement.
- Conditions
- Cardiovascular Disease, Aortic Valve Stenosis, Cognitive Assessments, Valve Surgery
- Trial name
- CAVIAR (NCT02971020)
- Testing
- Observational/Cognitive Assessment
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Minnesota Veterans Medical Research and Education Foundation
CT Coronary Angiography, Arterial Switch Operation
CT Coronary Angiography After Arterial Switch Operation
The purpose of this study is to find a non-invasive alternative (with using ECG gated 64-slice CT angiography) to invasive coronary angiography for detecting coronary lesions in patients who had undergone arterial switch…
- Trial name
- SCANTGV (NCT01153776)
- Testing
- 64-slice CT angiography
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Systemic Inflammatory Response Syndrome, Posttraumatic Stress Disorder
Influence of Hydrocortisone on Immunologic Markers and Health Care Related Quality of Life in Patients After Cardiac Surgery
Hydrocortisone has been shown to improve the early outcome of high risk patients after cardiac surgery. A potential mechanism resulting in this effect may be its immunomodulatory action.
- Trial name
- NCT00490828
- Testing
- Hydrocortisone
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Ludwig-Maximilians - University of Munich