Clinical trials: Patients Undergoing General Anesthesia
Central Venous Catheters
The Success Rate of Catheter Insertion by the Presence of Obturator During Peripherally Inserted Central Venous Catheter
In pediatric patients under the age of 18 who undergo surgery under general anesthesia, when inserting peripherally inserted central venous catheterization, the group that inserts the catheter with the obturator and the group…
- Trial name
- NCT04393844
- Testing
- turbo-ject PICC set
- Where
- South Korea
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
General Anesthesia; Pediatric Surgery; Intraoperative Music Therapy; Operating Room Noise Reduction; Anesthetic Requirement; Analgesic Requirement
Effect of Intraoperative Instrumental Music and Operating Room Noise Reduction on Anesthetic and Analgesic Requirements in Pediatric Patients Aged 3-18 Years Undergoing Surgery Under General Anesthesia: A Randomized Controlled Trial
This randomized controlled clinical trial aims to evaluate the effects of intraoperative instrumental music and operating room noise reduction on anesthetic and analgesic requirements in pediatric patients aged 3-18 years…
- Trial name
- MUSIC-OR (NCT07630675)
- Volunteers
- 180 people
- Sponsor
- Ankara City Hospital Bilkent
General Anesthesia, Blood Pressure
Assessment of Effectiveness of Continuous Non-invasive Haemodynamic Monitor by Compared to Invasive Blood Pressure and Pulse Oximeter Monitoring on Patients Undergoing General Anesthesia Surgeries for More Than 60 Minutes
The goal of this observational study is to assess whether the continuous non-invasive haemodynamic monitor MOH200 (measuring blood pressure as well as pulse rate) is effective or not in people undergoing general anesthetic…
- Conditions
- General Anesthesia, Blood Pressure, Pulse Rate, Arterial Line
- Trial name
- NCT06383000
- Volunteers
- 55 people
- Sponsor
- BLZ Technology (Wuhan) Co.,Ltd
Postoperative Nausea and Vomiting
Aprepitant PO vs Ondansetron IV for Prevention of Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) persists as one of the more common complications of surgery. Although rarely life-threatening, it is the postoperative outcome that is most unfavorable to patients, even more undesirable…
- Trial name
- NCT00699894
- Testing
- aprepitant 40 mg, ondansetron 4 mg
- Where
- United States
- Sponsor
- Northwell Health
Inguinal Hernia
Awake Caudal Catheter vs General Anesthesia
It is well established that preterm inguinal hernias discovered in the NICU pose a significant surgical risk due to the associated co-morbid conditions that accompany these patients.
- Trial name
- NCT05919732
- Testing
- Bupivacaine, Dexmedetomidine, Caffeine, Tylenol, Propofol, rocuronium, caffeine, Tylenol, bupivacaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Postoperative Recovery, Pediatric Anesthesia
Timing of Aminophylline and Recovery in Pediatric Ambulatory Surgery
Beyond its established use as a bronchodilator and therapy for apnea of prematurity, aminophylline has demonstrated utility in reversing the effects of anesthetics, enhancing recovery by accelerating respiratory and cognitive…
- Conditions
- Postoperative Recovery, Pediatric Anesthesia, Ambulatory Surgery
- Trial name
- ELEAR-PAP (NCT07011134)
- Testing
- Group (E): receive aminophylline early intraoperatively,, Group (L) received aminophylline late intraoperatively, Group (C) will receive normal saline post-anesthetic discontinuation.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Hany Mohammed El-Hadi Shoukat Mohammed
Anesthesia, Intravenous, Hemodynamic Stability
Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery
This single-center study at CHA Ilsan Medical Center compares intraoperative hemodynamics between remimazolam- and propofol-based total intravenous anesthesia (TIVA) in patients undergoing robot-assisted gynecologic surgery…
- Conditions
- Anesthesia, Intravenous, Hemodynamic Stability, Gynecologic Surgery
- Trial name
- By_HD (NCT07251101)
- Testing
- Remimazolam, Propofol
- Where
- 2 sites in South Korea
- Volunteers
- 58 people
- Sponsor
- Ilsan Cha hospital
Airway Management, Anesthesia, General
Video Laryngeal Mask SaCoVLM Versus LMA Supreme and Ambu AuraGain in Children
This randomised controlled trial compares three supraglottic airway devices (laryngeal masks) in children with a body weight of 3-30 kg undergoing elective surgery under general anaesthesia: the SaCoVLM video laryngeal mask (UE…
- Conditions
- Airway Management, Anesthesia, General, Pediatric Anesthesia
- Trial name
- SACOVLM-PEDI (NCT07891832)
- Testing
- SaCoVLM video laryngeal mask, LMA Supreme, Ambu AuraGain
- Where
- Czechia
- Volunteers
- 135 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Aneurysm Abdominal, Endovacular Repair
Post Implantation Syndrome and Administration on NSAIDs in Patients Undergoing EVAR for AAA
INTRODUCTION Post-implantation syndrome is the clinical and biochemical expression of an inflammatory response following endovascular repair of an aortic aneurysm.
- Trial name
- NCT03727412
- Testing
- Drugs, Generic (Naprosyn)
- Where
- Greece
- Volunteers
- 186 people
- Sponsor
- University of Thessaly
Pulmonary Aspiration of Gastric Contents
Comparison of Different Preoperative Fasting Times in Pediatric Patients Undergoing Elective General Anaesthesia
Rationale of this study is to provide an evidence on minimal safe clear fluid fasting duration without the risk of aspiration of gastric contents during elective pediatric procedures under general anesthesia.
- Trial name
- NCT05922072
- Testing
- Nasogastric aspiration for measurement of Residual Gastric Volume, Nasogastric Aspiration for Measurement of Gastric pH
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- King Edward Medical University
Strabismus
Peribulbar Block for Prevention of Oculocardiac Reflex
Strabismus is a common ophthalmic problem in Egypt that usually requires surgical correction. This surgery primarily aims to improve alignment of visual axis but may be required only for cosmetic reasons.
- Trial name
- NCT04549844
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Fayoum University Hospital
Hypovolemia
Lung Recruitment Maneuver for Predicting Fluid Responsiveness in Children
Lung recruitment maneuver induces a decrease in stroke volume, which is more pronounced in hypovolemic patients. The authors hypothesized that the changes of dynamic variables through lung recruitment maneuver could predict…
- Trial name
- NCT03184961
- Testing
- lung recruitment maneuver
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Mechanical Ventilation, Lung Protective Ventilation
Driving Pressure Guided Mechanical Ventilation Versus Lung Protective Ventilation Among Patients Undergoing Elective Surgeries
Patient undergoing surgeries in general anesthesia require support of their breathing by ventilator. Different strategies can be used to manage breathing of the patient.
- Conditions
- Mechanical Ventilation, Lung Protective Ventilation, Driving Pressure
- Trial name
- NCT07092943
- Testing
- Lung protective ventilation, Driving pressure guided ventilation
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Brain Neoplasms
Dexmedetomidine and Intelligence Development in Pediatric Patients Undergoing Craniotomy
The purpose of this randomized, double-blind and placebo-controlled pilot study is to investigate whether dexmedetomidine when used as an adjuvant to general anesthesia can decrease the harmful effects of anesthesia and surgery…
- Trial name
- NCT02810899
- Testing
- dexmedetomidine, normal saline
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University First Hospital
Tonsillectomy Postoperative Adverse Events
Factors Predictive of Adverse Postoperative Outcomes in Children Undergoing Tonsillectomy
The purposes of the study are to identify 1) the patient (demographic and clinical) and health care system factors predictive of immediate and late postoperative adverse outcomes in children undergoing tonsillectomy.
- Trial name
- NCT01669993
- Where
- United States
- Volunteers
- 2,400 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Respiratory Complications
The Evaluation of a Noninvasive Respiratory Monitor in Pediatric Patients Undergoing General Anesthesia
Pediatric postoperative patients are at increased risk for post-operative respiratory complications such as hypoventilation. There is no objective measure of early respiratory parameters that would predict respiratory compromise…
- Trial name
- NCT02336022
- Testing
- Respiratory Motion Inc
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Boston Children's Hospital
Hypovolemia
Fluid Responsiveness Using Forehead Sensor in Children
Forehead sensor can predict the more accurate fluid responsiveness than finger sensor in children
- Trial name
- forehead (NCT03132480)
- Testing
- fluid resuscitation
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Anesthesia; Adverse Effect
Does Sevoflurane Cause Genomic Damage
This study aims to find out if sevoflurane causes any cell damage to patients undergoing general anaesthesia. In case of any damage, the reversibility of the damage is also assessed.
- Trial name
- NCT03109119
- Testing
- Sevoflurane, Propofol
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Post-Operative Nausea and Vomiting
A Study of Kytril (Granisetron) in the Prevention of Post-Operative Nausea and Vomiting (PONV) in Pediatric Subjects Undergoing Tonsillectomy or Adenotonsillectomy
This 2 arm study will evaluate the efficacy and safety of a single intravenous injection of Kytril in preventing postoperative nausea and vomiting (PONV) in children.
- Trial name
- NCT00231478
- Testing
- granisetron
- Where
- 11 sites in United States
- Volunteers
- 171 people
- Sponsor
- Hoffmann-La Roche
Anesthesia
SedLine Engineering Data Collection Study in Pediatric Patients Undergoing General Anesthesia or Sedation
The purpose of the study is to collect EEG data with the Masimo SedLine device along with vital signs, patient demographics, anesthetic record and surgical procedure during general anesthesia or sedation.
- Trial name
- NCT03128931
- Testing
- Pediatric SedLine forehead EEG sensor
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Masimo Corporation