Clinical trials: Patients in ICU
Limb Fracture
Impact of Continuous Regional Analgesia in Severe Trauma Patients
Regional analgesia, based on its physiological effects and efficacy, is used for optimal perioperative pain relief. However, for acute pain in multiple trauma patients in a critical condition, it has not been prospectively…
- Trial name
- ALRréa (NCT04546503)
- Testing
- Continuous Regional analgesia, Control Group
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Interprofessional Relations, Interprofessional Education
Interprofessional Collaboration in the Cardiac Intensive Care Unit (CICU): An Action-Research Training Project
This study evaluates the impact of a structured interprofessional training program on daily collaboration within the Cardiac Intensive Care Unit (CICU/UTIC) at the University Hospital of Parma.
- Conditions
- Interprofessional Relations, Interprofessional Education, Attitude of Health Personnel, Intensive Care Units
- Trial name
- COLLUTIC_25 (NCT07360366)
- Testing
- The training phase of the project consists of an interactive course aimed at healthcare professionals (physicians, nurses and OSS) to improve their ability to recognise and enact effective collaborati
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Patient Safety, Organizational Change
Generalizing TESTPILOT to New Single Family Room NICUs
Complex service interventions are neither smooth nor easy in any transitioning healthcare facility. Simulations performed in the new environment reinforce patient safety by uncovering safety threats, enabling their correction…
- Trial name
- TESTPILOT (NCT02574104)
- Testing
- Simulate a functional NICU prior to moving patients
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Critical Illness
Lactoferrin Use in ICU Patients
Introduction: Lactoferrin has several uses due to its effects. It has anti-inflammatory, antioxidant, immunomodulatory, antibacterial, antifungal, and antiviral effects. Its safety is proven by food and drug administration.
- Trial name
- RCT (NCT05936528)
- Testing
- Lactoferrin, Antioxidant therapies, Dexamethasone
- Where
- Egypt
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Prematurity
Evaluating Wearable Smart Sensors for Continuous Measurement of Vital Signs in ICU Patients
The purpose of this study is to develop biocompatible wireless electronic devices that will allow continuous, non-invasive hemodynamic and physiology measurements in the ICU.
- Trial name
- NCT04723654
- Testing
- Wireless Wearable Vital Sign Monitor
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Pressure Injury, Risk Assessment
Positioning Duration and Pressure Injury Risk
This research aims to investigate the effect of positioning times on the risk of pressure injury in critically ill patients.
- Trial name
- PIP-ICU (NCT07355439)
- Testing
- Position Change - 1 Hour, Position Change - 2 Hours
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- SEMA ŞAHİNER
Intensive Care Units, Pediatric, Massage
The Effect of Abdominal Massage on Gastric Problems in Pediatric Intensive Care: A Randomized Controlled Study
Many system functions differ in children dependent on mechanical ventilation support and may present with various complications.
- Conditions
- Intensive Care Units, Pediatric, Massage, Nutrition Disorders, Nurse's Role
- Trial name
- NCT04841174
- Testing
- Abdominal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Anxiety Disorder/Anxiety State
The ICU is a Complex Setting Where Critically Ill Patients Are Treated, Impacting Caregivers' Mental Health, Leading to Anxiety and Depression .we Aim to Identify the Prevalence of Anxiety and Depression Among Family Members of ICU Patients in a Tertiary-Level Hospital in Nepal
a prospective observational study conducted in ICU of tertiary hospital under the guidance of mentors of department of critical care medicine TUTH to identify the Prevalence of Anxiety and Depression Among Family Members of ICU…
- Trial name
- HADS (NCT06835673)
- Where
- Nepal
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Seizures
Seizure Identification on the Intensive Care Unit (ICU)
The aim of this project is to assess the ability of different groups of National Heath Service (NHS) professionals to correctly identify clinical seizures, and distinguish them from other movements commonly seen in the ICU…
- Trial name
- NCT07136298
- Testing
- Clinical Opinion
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Sepsis, Septic Shock
Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
Background: Central Venous catheter insertion technique and indwelling time are major risk factors for CVC colonisation. Colonisation occurs through microbial migration and biofilm formation along the catheter insertion tract.
- Conditions
- Sepsis, Septic Shock, Post-cardiac Surgery, Post-Cardiorespiratory Arrest Coma
- Trial name
- NCT03270774
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makerere University
Medically Complex Infants
Effects of Medical Complexity Using GMA on Lurie Children's In- and Outpatients
The purpose of this study is to research a new type of test for cerebral palsy that can be performed earlier, at 10-15 weeks of age (after the due date for premature infants).
- Trial name
- CIMA (NCT01659710)
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Raye Ann deRegnier
Clinical Outcomes
Pattern of Disease and Determinants of Clinical Outcomes Among ICU Patients
The global mortality rate of patients on MV is very high which is varied with the income level of the country, duration of a mechanical ventilator, the pattern of disease, ICU staff profile, availability of medical supplies.
- Trial name
- PDCO (NCT05303831)
- Testing
- Mechanical ventilator
- Where
- Ethiopia
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Dilla University
Sedated ICU Patients
IMPROVE Critical Care Study (Pilot)
The Pilot Clinical Investigation planned is a prospective, unblinded randomized pilot trial comparing sedation management using a protocol based on responsiveness with standard sedation management.
- Trial name
- NCT01361230
- Testing
- "Sedation Trial Monitor" is the name of the device used.
- Where
- United Kingdom
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
ICU Staff Attitudes Toward Family Presence, ICU Staff Experience of Family Presence
Attitudes, Experience and Adaptation to Family Presence in the ICU
The goal of the study is to verify how healthcare professionals in the Intensive Care Unit (ICU) experience the presence of family members before and after a more flexible visiting policy is introduced.
- Conditions
- ICU Staff Attitudes Toward Family Presence, ICU Staff Experience of Family Presence, Adaptation to Extended Family Presence in the ICU, Association Between Stress Sensitivity and Attitudes Toward Family Presence
- Trial name
- RUIMIZ (NCT07887009)
- Testing
- questionnaire
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Education, Health
Simulation Training as a Tool to Decrease Occupational Stress in ICU Personnel
The purpose of the study is to check wether training mixed teams of physicians and nurses from intensive care units on patient simulators reduces stress in team members.
- Trial name
- NCT00232323
- Testing
- simulation training
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Delirium
The ICU DElirium in Clinical PracTice Implementation Evaluation Study Screening and Treatment
Objective: Delirium is an important and frequently occurring complication in intensive care patients. However, screening and treatment of delirium is not in accordance with current national and international guidelines.
- Trial name
- iDECePTIvE (NCT01952899)
- Where
- Netherlands
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Terminally Ill Patients
Mobile Shared Decision-Making Program for ICU Caregivers
By developing a smart mobile shared decision-making (SDM) model, this study aims to assist family members of critically ill end-stage patients in making appropriate decisions, enhance their decision quality, and evaluate the…
- Trial name
- NCT07469878
- Testing
- Experimental: Mobile technology devices
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- CHIA-HUI MA
Critical Illness, Pneumonia, Viral
D-Dimer as Predictor of Disease Outcome in Intensive Care Unit in COVID-19m Patients
Evaluating value of D-Dimer blood level of icu admitted patients on admission and 48 hours later as outcome predictor in SARS.COV.2 patients.
- Trial name
- COVID-19 (NCT05279469)
- Testing
- no intervention, just observational for D-Dimer level in blood
- Where
- 2 sites in Egypt
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Intensive Care Units, Triage
ICU Triage Practices in a Cancer Hospital
The primary objective of this study is aimed at analyzing the ICU triage practices of clinicians at a cancer hospital with and without the use of an algorithm-based triage tool, and to assess whether or not the triage tool…
- Trial name
- NCT03401411
- Testing
- Survey, Algorithm-based Triage Tool
- Where
- 3 sites in United States, Ecuador
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Prematurity
Ultrasound Monitoring of Muscle Thickness in Premature Patients
The goal of this interventional study is to investigate through musculoskeletal ultrasonography how the thickness and muscle trophism in infants aged 28 to 35 weeks undergoing infant massage compared with a group of infants with…
- Trial name
- NeoMassage (NCT06273202)
- Testing
- Infant Massage
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS