Clinical trials: Pediatric
Irritable Bowel Syndrome With Constipation (IBS-C)
Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years
This is a randomized, double-blind, placebo-controlled study to assess the efficacy, safety and tolerability of tenapanor (25 mg and 50 mg) in pediatric patients (≥12 and <18 years old) with IBS-C when administered twice daily…
- Trial name
- NCT05643534
- Testing
- Tenapanor 50 MG, Tenapanor 25 mg bid
- Where
- 39 sites in United States
- Volunteers
- 180 people
- Sponsor
- Ardelyx
Pain
Sub-dissociative Ketamine for the Management of Acute Pediatric Pain
The proposed trial is a prospective, double blinded, randomized control trial with the primary aim of determining whether a single, sub-dissociative dose of ketamine will decrease the total narcotic requirements of pediatric…
- Trial name
- NCT01951963
- Testing
- Ketamine, Morphine
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- HealthPartners Institute
Comparison, the Efficacy of Levetireacetam
Levetiracetam Versus Phenytoin in Management of Pediatric Status Epilepticus
The study will be conducted on 60 children suffering from status epilepticus who will be admitted to Pediatric Neurology Unit and Pediatric ICU of Tanta Hospital University.
- Conditions
- Comparison, the Efficacy of Levetireacetam, Phenytoin, Management of Pediatric Status Epilepticus
- Trial name
- NCT04176887
- Testing
- Levetiracetam Injection, Phenytoin Injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Multiple Sclerosis
Endeavor™ in Pediatric MS
This study will examine the feasibility of using an Endeavor™ application as a treatment modality for cognitive impairments in the pediatric MS population.
- Trial name
- Akili (NCT04445116)
- Testing
- Action Video Game Treatment
- Where
- United States
- Sponsor
- NYU Langone Health
Craniopharyngioma, Obesity
Multicenter Registry for Patients With Childhood.Onset Craniopharyngioma, Xanthogranuloma, Cysts of Rathke's Pouch, Meningioma, Pituitary Adenoma, Arachnoid Cysts
KRANIOPHARYNGEOM Registry 2019 will prospectively collect and descriptively analyse data on diagnostics, treatment, and follow-up of patients with craniopharyngioma.
- Trial name
- NCT04158284
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Klinikum Oldenburg gGmbH
Neuromuscular Performance, Reaction Time
Effects of Virtual Reality Exergaming on Reaction Time, Physical Performance, and Muscle Activity in Children
This randomized controlled trial will investigate the immediate effects of virtual reality (VR) exergaming on reaction time, physical performance, balance, and muscle activity in children aged 10-14 years with different athletic…
- Conditions
- Neuromuscular Performance, Reaction Time, Postural Balance
- Trial name
- PED-VR-EMG (NCT07916155)
- Testing
- Immersive Virtual Reality Exergaming
- Where
- Romania
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Pediatric Patient With Early Loss of Primary Teeth
Comparative Evaluation of Pediatric Patient Comfort, Time, and Preference Between Digital Scans and Rubber Base Impressions. Crossover Study Randomized Controlled Trial
The comfort of impression methods and the time they require are important because it is known that children are more stressed in their encounter with the dentist than the elderly, and their chairside times are shorter.
- Trial name
- NCT06833385
- Testing
- Intraoral Scanning, PVS Impression
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Yasmine Ahmed Mortada Abd Elfatah
Sarcoma
Late Effects of Treatment for Sarcomas in Children
This study will examine late effects of treatment for sarcoma (bone and soft tissue cancers) in children. Survival of patients with these diseases has improved over the years, but long-term adverse effects of treatment have also…
- Trial name
- NCT00006515
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- National Cancer Institute (NCI)
Elevated Blood Pressure
Office, Home, and Ambulatory Blood Pressure
This will be a prospective observational study. The population would be pediatric patients 6 years to <19 years of age who were referred for elevated blood pressure to investigate if home blood pressure (HBP) can determine blood…
- Trial name
- HBPA (NCT05297708)
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Procedural Fear in Children, Difficult Intravenous Access
Effect of a Musical-Moving Toy Used During Difficult Peripheral Intravenous Catheterization on Children's Fear Level and Procedure Success
Peripheral intravenous catheterization (PIVC) is a frequently performed invasive procedure in pediatric emergency departments and is often associated with fear and distress in children.
- Trial name
- NCT07459517
- Testing
- Musical-Moving Toy Distraction
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Psoriasis
Safety, Tolerability, PD & PK of Calcipotriene 0.005% Foam, Under Maximal Use in 12-16 Year Olds With Plaque Psoriasis
Calcipotriene is a vitamin D3 analog that has been used as topical therapy in adult subjects with plaque-type psoriasis since 1993.
- Trial name
- NCT01563068
- Testing
- Calcipotriene 0.005% Foam
- Where
- 9 sites in United States
- Volunteers
- 18 people
- Sponsor
- Mayne Pharma International Pty Ltd
Parents, Anxiety Postoperative
Impact of Postoperative Medical Equipment Removal/insertion on Parental Anxiety in Pediatric Cardiac Intensive Care Unit
A lot of observationnal studies describe parental stressors in PICU/PCICU, but none studied, prospectively, the links between medical equipment removal/insertion and anxiety modulation.
- Trial name
- NCT05892874
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Claude Bernard University
Dental Caries
Zirconomer-P Versus RMGI for Proximal Restorations in Primary Molars
Clinical trial comparing two tooth-colored restorative materials for treating cavities between the teeth of primary molars in children aged 4 to 7 years.
- Trial name
- NCT07788274
- Testing
- Zirconia-fortified glass ionomer, Resin-modified glass ionomer
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Pediatric Hematology, Pediatric Oncology
Effect of Hand Puppet and Squeeze Toys on IV Placement in Pediatric Oncology Patients
This randomized controlled trial investigates hand puppet and squeeze toy techniques to reduce fear, emotional distress, and procedure time, and improve IV catheter placement success in 90 pediatric hematology-oncology patients…
- Trial name
- NCT07493018
- Testing
- Performing a Hand Puppet to Music, Hand Squeezing Soft Toy (Squishy)
- Volunteers
- 90 people
- Sponsor
- Akdeniz University
Adolescent Idiopathic Scoliosis
Application of Virtual Reality in Post-Operative Recovery of a Pediatric Scoliosis Patient Population
The purpose of this study is to assess the effect of virtual reality on subjective post-operative pain, total inpatient narcotic administration, and mobilization with physical therapy in pediatric patients who have undergone…
- Trial name
- NCT06101264
- Testing
- Control, Virtual Reality
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Connecticut Children's Medical Center
Heart Defects, Congenital
Pediatric Exercise With Congenital Heart Defects (Kinderturnen Mit Angeborenem Herzfehler)
Children with congenital heart defects have shown to develop motor coordinative deficiencies. In this study we want to show that a motor pedagogic physical training can improve the coordinative capabilities of children aged 4-6…
- Trial name
- NCT00436098
- Testing
- Motorpedagogic exercise
- Where
- 2 sites in Germany
- Volunteers
- 60 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Preoperative Anxiety, Dental Anxiety
Digital Storytelling-Based Animation for Preoperative Anxiety in Children
This randomized controlled trial evaluates the effect of a digital storytelling-based animation on preoperative anxiety and physiological parameters in children aged 5-12 years undergoing dental treatment under general…
- Trial name
- NCT07825493
- Testing
- Digital Storytelling-Based Animation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Recep Tayyip Erdogan University
Childhood Obesity, Feeding Behavior
Evaluation of a Primary Care Weight Management Program in Children Aged 2 to 5 Years
Primary care offers a promising setting for promoting parenting practices that shape healthy eating and physical activity behaviors of young children.
- Conditions
- Childhood Obesity, Feeding Behavior, Physical Activity
- Trial name
- NCT03487614
- Testing
- Behavior-based parental intervention
- Volunteers
- 184 people
- Sponsor
- Corewell Health West
Pediatric, Anesthesia Induction
The ED95 of Ciprofol for Laryngeal Mask Airway Insertion With Fentanyl in Children: A Biased-Coin Dose-Finding Trial
Ciprofol is a novel intravenous anesthetic with a pharmacological profile similar to propofol but with a lower incidence of injection pain, hypotension, and respiratory depression.
- Conditions
- Pediatric, Anesthesia Induction, Ciprofol, Laryngeal Mask Airway
- Trial name
- NCT07697404
- Testing
- Ciprofol, Fentanyl
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Huazhong University of Science and Technology
Hematologic Malignancy
Evaluation of PET/MRI in Children With Cancer
This research study is a Pilot study (a small preliminary study to assess the feasibility of a larger, more in depth study involving a new test or procedure) and is being done to evaluate the feasibility and accuracy of PET/MRI…
- Trial name
- NCT01839747
- Testing
- PET-MRI, PET-CT
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
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