Clinical trials: Pediatric Population
Pneumonia Childhood
Severe Pneumonia Diagnostic in Pediatric Population by Lung Ultrasonography and Procalcitonin
Lung ultrasound (LUS) in combination with a biomarker has not yet been studied. The investigators propose a clinical trial where the primary aims are: 1.
- Trial name
- PROLUSP (NCT04217980)
- Testing
- Lung ultrasonography (LUS) or Chest X ray (CXR)
- Where
- 2 sites in Spain
- Volunteers
- 202 people
- Sponsor
- Fundació Sant Joan de Déu
Lennox Gastaut Syndrome (LGS)
A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome
The aims of the study are: to learn if soticlestat, when given as add-on therapy, reduces the number of major motor drop seizures in children, teenagers, and adults with Lennox-Gastaut Syndrome.
- Trial name
- NCT04938427
- Testing
- Soticlestat
- Where
- 98 sites in United States, Australia and 16 more
- Volunteers
- 270 people
- Sponsor
- Takeda
Metabolism and Nutrition Disorder
Prospective Evaluation of the Incidence of PICS
Advances in modern medicine and critical care interventions have greatly impacted survival of critically ill patients, but these interventions are not without consequences.
- Trial name
- ProsPICS (NCT03584399)
- Testing
- PICS in critically ill pediatric population
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
Perforated Appendicitis
The Management of Perforated Acute Appendicitis in Adult and Pediatric Populations
Patients admitted at Marshall Health - Cabell Huntington Hospital with the diagnosis of acute perforated appendicitis or appendicular abscess larger than 3cm will be admitted and treated with percutaneous drainage and the IV…
- Trial name
- NCT04253899
- Testing
- Appendectomy, Observation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Marshall University
Appendicitis
Transversus Abdominis Plane (TAP) Versus Local Anesthetic for Lap Appendectomies
This study is a prospective, double-blinded, randomized comparison of 2 patient cohorts. One group of patients will receive a transversus abdominis plane (TAP) block.
- Trial name
- NCT01575028
- Testing
- Ropivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Nationwide Children's Hospital
SARS-CoV-2 Infection
COVID-10 in the Pediatric Population: SARS-CoV-2 Seropositivity
The purpose of this study was to conduct an epidemiological survey of the pediatric population via SARS CoV-2 IgG antibody testing in order to evaluate the incidence of asymptomatic infection and seropositivity among children and…
- Trial name
- NCT04690114
- Where
- Israel
- Volunteers
- 2,000 people
- Sponsor
- Shaare Zedek Medical Center
Pediatric ALL
Measurement of Spinal Mobilization in Pediatric Population
The goal of this cross-sectional study is to measure the biomechanical parameters during a vertebral mobilization delivered by chiropractors on patients of five years old of age and younger.
- Trial name
- NCT05607355
- Where
- Canada
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Université du Québec à Trois-Rivières
Health Literacy, Health Related Quality of Life
Feasibility of a Life Coping Program: A Study Protocol
The goal of this observational study is to evaluate the feasibility of the intervention Life Coping Program in children and adolescents 8-16 years of age.
- Conditions
- Health Literacy, Health Related Quality of Life, Physical Activity, Pediatric ALL
- Trial name
- LifeCOPE (NCT06709248)
- Testing
- Life Coping Program
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Haukeland University Hospital
Allergic Rhinitis
Study of an Investigational Nasal Aerosol or Placebo in Children (Ages 4 to 11) With Perennial Allergic Rhinitis (PAR)
The purpose of this study is to evaluate the efficacy and safety of Beclomethasone dipropionate (BDP) nasal aerosol in subjects with Perennial Allergic Rhinitis (PAR).
- Trial name
- NCT01783548
- Testing
- BDP Nasal Aerosol
- Where
- 63 sites in United States
- Volunteers
- 547 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Pediatric Chronic Inflammatory Demyelinating Polyneuropathy
Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients
Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients
- Trial name
- NCT04929236
- Testing
- Panzyga
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Octapharma
Migraine
Efficacy and Safety of Erenumab in Pediatric Participants With Episodic Migraine
This study will evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and adolescents (12 to <18 years) with episodic migraine.
- Trial name
- OASIS(EM) (NCT03836040)
- Testing
- Erenumab Dose 1, Erenumab Dose 2, Erenumab Dose 3
- Where
- 11 sites in United States, Belgium and 2 more
- Volunteers
- 457 people
- Sponsor
- Amgen
Fabry Disease
A Study of Two Fabrazyme (Agalsidase Beta) Dosing Regimens in Treatment-naïve, Male Pediatric Patients Without Severe Symptoms
The purpose of this study was to determine whether 2 alternative dosing regimens of Fabrazyme (Agalsidase beta) (1.0 mg/kg every 4 weeks or 0.5 mg/kg every 2 weeks) were effective in treatment-naïve pediatric participants without…
- Trial name
- FIELD (NCT00701415)
- Testing
- Agalsidase beta
- Where
- 12 sites in United States, Argentina and 7 more
- Volunteers
- 31 people
- Sponsor
- Genzyme, a Sanofi Company
Neoplasms, Appendix Cancer
Value of Right-sided Hemicolectomy for Chldren With High-risk Neuroendocrine Tumors of the Appendix
The goal of this observational study is to investigate the beneficial value of complementary surgery for appendiceal neuro-endocrine tumours in children. .
- Trial name
- NETkids (NCT05919758)
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Mental Health Disorder
CoCo-20: a Longitudinal Follow-up Study of the French Paediatric Population During and After the Coronavirus Pandemic COVID-19
In the context of a viral outbreak and of widespread quarantine measures, a significant increase in psychological disorders, such as stress or fear behaviours, had previously been observed.
- Trial name
- CoCo-20 (NCT04498416)
- Testing
- Quantitative and qualitative assessments of mental health
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Fondation Lenval
Feeding and Eating Disorders of Childhood, Appetite Disorders
Biolizin for Improving Functional Poor Appetite in Children Aged 6 to 36 Months (CTBE2502)
Functional poor appetite is common in young children and may be linked to suboptimal micronutrient intake and feeding behavior. This study evaluates whether a zinc-containing oral supplement (Biolizin syrup) can improve eating…
- Conditions
- Feeding and Eating Disorders of Childhood, Appetite Disorders, Functional Poor Appetite
- Trial name
- CTBE2502 (NCT07153549)
- Testing
- Biolizin, Standardized caregiver counseling on responsive feeding
- Where
- Vietnam
- Volunteers
- 110 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children
Evaluation of Pain Management After Surgery When Using Exparel in the Pediatric Population
The goal of this randomized clinical trial is to determine if administration of Exparel via local infiltration for medial patellofemoral ligament (MPFL) reconstruction procedures in pediatric orthopaedic sports medicine patients…
- Conditions
- Medial Patellofemoral Ligament (MPFL) Reconstruction, Sports Injuries in Children, Analgesia, Pain, Postoperative
- Trial name
- NCT06559215
- Testing
- Exparel
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Pain, Burns
Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: Trial
Children with burn injuries experience severe pain intensity during medical procedures despite the increasing doses of analgesics.
- Conditions
- Pain, Burns, Child, Anxiety
- Trial name
- DREAM-T (NCT02947243)
- Testing
- VR distraction via Oculus Rift, Morphine
- Where
- Canada
- Sponsor
- St. Justine's Hospital
Gastroesophageal Reflux Disease (GERD)
A Study of the Safety and Effectiveness of Rabeprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Pediatric Patients
The purpose of the study is to access the effectiveness and safety of oral rabeprazole in the treatment of acid-related disorders in pediatric patients, focusing specifically on the manifestation of GERD (symptomatic and erosive…
- Trial name
- NCT00787891
- Testing
- rabeprazole
- Volunteers
- 127 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.