Clinical trials: Pediatric Surgical Procedures
Pediatric Patient
CAUDAL EPIDURAL BLOCK IN PEDIATRIC SURGERY CASES
Caudal epidural anesthesia was reported as the first epidural anesthesia technique in 1933, but its use began to become widespread after the 1960s (1).
- Trial name
- NCT06855199
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Cigdem Demirci
Opioid Consumption, Multimodal Analgesia
Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy
Magnesium sulfate is one of the most commonly used co-analgetics. Its antinociceptive effect is related to antagonizing NMDA (N-methyl-D-aspartate) receptors of the nervous system, has an anti-inflammatory effect by reducing the…
- Conditions
- Opioid Consumption, Multimodal Analgesia, Acute Appendicitis, Complication of Treatment
- Trial name
- NCT06563349
- Testing
- Intravenous magnesium sulfate, Normal saline infusion
- Where
- Poland
- Volunteers
- 188 people
- Sponsor
- Medical University of Warsaw
Postoperative Cognitive Dysfunction, Postoperative Delirium
Perioperative GDNF as a Predictive Factor for Postoperative Delirium and Adverse Neurological Outcomes in Pediatric Surgery
To observe the dynamic changes in serum levels of inflammatory cytokines (e.g., IL-6, TNF-α), Brain-Derived Neurotrophic Factor (BDNF), and Glial Cell Line-Derived Neurotrophic Factor (GDNF) during the perioperative period in…
- Trial name
- NCT07192549
- Testing
- Sevoflurane group, Propofol group
- Volunteers
- 200 people
- Sponsor
- General Hospital of Ningxia Medical University
Pediatric Surgery
Impact of an Information Assistance Application in Addition to a Traditional Anesthesia Consultation on Preoperative Anxiety in Pediatrics: Prospective Randomized Trial
The objective of the study is to evaluate the benefits on pre-operative anxiety of an information assistance application in addition to a traditional anesthesia consultation on preoperative anxiety in pediatrics
- Trial name
- Anx'Appli (NCT05401617)
- Testing
- additional information via the computerized tool
- Where
- France
- Volunteers
- 182 people
- Sponsor
- University Hospital, Rouen
Intestinal Diseases, Intestinal Resection
Implementation of a Pediatric ERAS-based Protocol in Intestinal Resection With Primary Anastomosis
Enhanced Recovery After Surgery (ERAS) is a multimodal perioperative care strategy designed to reduce surgical stress, decrease postoperative complications, and accelerate recovery after surgery.
- Trial name
- PeERAS (NCT07504549)
- Testing
- Standardized Pediatric ERAS-Based Perioperative Protocol
- Where
- 9 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Michał Pasierbek
Pediatric Surgical Patient
Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Pediatric Surgical Patients
Oxycodone is an oral opioid analgesic that is most commonly prescribed for the management of pain in post-operative patients at Boston Children's Hospital.
- Trial name
- NCT02044497
- Testing
- oral oxycodone
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Boston Children's Hospital
Cleft Lip, Cleft Palate
Characterization of Cleft Lip and Palate Conditions in Guatemala
The purpose of this study is to compare types of and risk factors for cleft lip and palate in a Guatemalan population to a United States population.
- Conditions
- Cleft Lip, Cleft Palate, Cleft Lip and Palate
- Trial name
- NCT04725370
- Testing
- NA - survey instrument
- Where
- United States
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Easy Insertion, Complications Ans Suitability of i Gel and Air Q LMA
I-gel Versus Air-Q LMA for Pediatric Patients
This study targets to compare insertion facility, effect on hemodynamic parameters and effective ventilation using i-gel versus Air-Q LMA for pediatric patients undergoing short-duration surgical procedures.
- Trial name
- NCT04458064
- Testing
- LMA i gel
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Postoperative Pain
Clinical Meaning of Visual Analog Scales(VAS) for Teenage Pediatric Patients Undergoing Laparoscopic Surgical Procedures
The purpose of this study is to find a more accurate postoperative pain assessment for teenager patients. This is important because a patient should not have a very strong pain medication such as morphine if the pain is just mild.
- Trial name
- NCT01755065
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- University of Pittsburgh
Cleft Lip, Cleft Palate
Primary Palatoplasty in Pediatric Patients - A Retrospective Review of Surgical Outcomes
Children who are born with cleft palate need surgery in order to correct the problem. The surgery is needed because the defect allows food to leak into the nose.
- Trial name
- NCT01380171
- Where
- United States
- Volunteers
- 1,295 people
- Sponsor
- Children's Healthcare of Atlanta
Supracondylar Humerus Fracture, Vascular Trauma
Necessity of Vascular Surgical Intervention in Pulseless Supracondylar Fractures in Children
The main idea of the study is to evaluate and compare procedures and results in the treatment of pulseless supracondylar fractures in specialized pediatric surgery and traumatology departments.
- Conditions
- Supracondylar Humerus Fracture, Vascular Trauma, Ischemia
- Trial name
- pulseless-pink (NCT07832058)
- Testing
- Vascular surgical intervention
- Where
- 11 sites in Czechia, Slovakia
- Volunteers
- 190 people
- Sponsor
- University Hospital Hradec Kralove
Anesthesia, Neuromuscular Blockade
Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizing Muscle Relaxants
Although tonsillectomy is one of the most commonly performed surgeries, a review of literature reveals no articles dealing with the study of intraoperative blood loss in tonsillectomy and adenotonsillectomy according to the use…
- Conditions
- Anesthesia, Neuromuscular Blockade, Intraoperative Bleeding, Intraoperative Blood Loss
- Trial name
- NCT06399445
- Testing
- conventional cold tonsillectomy and curettage adenoidectomy, Rocuronium Bromide
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital of Split
Pediatric, Fracture
Investigation Of Bioabsorbable Screws In Pediatric Orthopedic Surgery
This study is a prospective randomized controlled trial comparing the clinical outcomes of bioabsorbable screws to conventional metal screws in pediatric patients (aged 0 to 18) undergoing surgical fixation for trauma or elective…
- Conditions
- Pediatric, Fracture, Orthopedic Devices Associated With Misadventures, Surgical Instruments, Materials and Devices (Including Sutures), Patient Satisfaction
- Trial name
- NCT06429267
- Testing
- Bioabsorbable Screw, Metal/Titanium Screw
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Tonsillectomy, Adenotonsillectomy
Celecoxib for Pediatric Adenotonsillectomy
The investigators' study will involve the administration of either placebo or celecoxib to children aged 2 to 18 years of age undergoing tonsillectomy and assessing pain relief, impact on quality of life and side effect profile.
- Conditions
- Tonsillectomy, Adenotonsillectomy, Pain, Postoperative
- Trial name
- NCT00849966
- Testing
- Celebrex suspension
- Where
- Canada
- Volunteers
- 282 people
- Sponsor
- Children's Hospital of Eastern Ontario
Perfusion, Fluorescence Imaging
Micro-dosing Indocyanine Green (ICG) in Children
The goal of this cohort study is to identify the lowest dose of Indocyanine Green (ICG) that achieves satisfactory intra-operative fluorescence for the assessment of gastrointestinal or genitourinary tract perfusion in children.
- Conditions
- Perfusion, Fluorescence Imaging, Gastrointestinal Tract Disorders, Genitourinary Disease
- Trial name
- NCT06421103
- Testing
- Indocyanine Green (ICG)
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Pharmacokinetics, Pharmacogenomics
Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Thai Pediatric Surgical Patients
This study is designed as an experimental trial which collect prospective data at Mahidol university. It aims to characterize the responses of Thai pediatric population,age 1 - 6 years, to oxycodone oral syrup and its metabolites…
- Conditions
- Pharmacokinetics, Pharmacogenomics, Oxycodone
- Trial name
- PedPK (NCT03145272)
- Testing
- Oxycodone
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Surgical Site Infection, Vancomycin
Pharmacokinetics of Preoperative Vancomycin
A study of plasma and tissue vancomycin pharmacokinetics in pediatric surgical patients.
- Trial name
- NCT03453684
- Testing
- Administration of Vancomycin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Ventilator Lung, Surgery
Monitoring of Lung Ventilation Through Electrical Impedance Tomography During Pediatric Surgery
Given the scarcity of studies aimed at assessing the effect of anesthesia and m ventilation on the distribution of lung ventilation in pediatric patients undergoing surgery, with the exclusion of thoracic surgery, the present…
- Conditions
- Ventilator Lung, Surgery, Pediatric
- Trial name
- VentiPed (NCT06370507)
- Testing
- Electrical impedance tomography assessment of ventilation distribution in course of sedation/general anesthesia for pediatric surgery
- Volunteers
- 800 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
General Anesthetic, Electroencephalogram
General Anesthetics-related Changes in Prefrontal EEG During Pediatric Surgical Anesthesia
The change profiles of indices derived from pEEG such as phase-amplitude coupling and bicoherence based on individual general anesthetics in children have not been examined in previous literature.
- Trial name
- NCT05210764
- Testing
- propofol, sevoflurane, S-ketamine
- Where
- China
- Volunteers
- 366 people
- Sponsor
- Peking University First Hospital
Child, Only
Pediatric Ultrasound-guided Dorsal Penile Nerve Block Plus Sedation in Spontaneous Breathing
One of the most frequent surgical procedures in the pediatric population is circumcision, following which postoperative pain could be stressful.
- Trial name
- NCT04475458
- Testing
- Ultrasound-guided dorsal penile nerve block
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine