Clinical trials: Pediatrics
Difficult Intubation
Video Classification of Intubation in Spain (VCI) (Pediatrics)
Use of VCI in Spain
- Trial name
- VCI (NCT06881576)
- Testing
- Compare VCI scale
- Where
- 2 sites in Spain
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Severe Hemophilia A
Pharmacokinetics, Efficacy, Safety, and Immunogenicity of Wilate in Previously Treated Paediatric Patients With Severe Haemophilia A
A prospective, non-controlled, international, multi-centre phase 3 study to investigate the pharmacokinetics, efficacy, safety, and immunogenicity of Wilate in previously treated children with severe haemophilia A
- Trial name
- NCT03376516
- Testing
- Wilate
- Where
- 3 sites in Russia, Ukraine
- Volunteers
- 11 people
- Sponsor
- Octapharma
Analgesia, Epidural
TAP vs Caudal Block Using Dexmedetomidine/ Bupivacaine for Post Operative Analgesia
Caudal epidural block is a well-established and commonly performed regional neuraxial technique for providing intraoperative and postoperative analgesia in children scheduled for lower abdomen/perineal surgical interventions.
- Trial name
- NCT03482947
- Testing
- ultrasonography-guided TAP block, Caudal epidural block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Anxiety, Paediatric
Comparison of Efficacy of Little Lovely Dentist, Dental Song and Tell-show-do Techniques in Alleviating Dental Anxiety in Paediatric Patients
To evaluate the efficacy of different techniques for the reduction of dental anxiety in pediatric patients. Generally, anxiety amongst paediatric patients is higher as compared to adult patients.
- Conditions
- Anxiety, Paediatric, Dental Anxiety, Behaviour
- Trial name
- NCT04833478
- Testing
- Anxiety
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Dysfunction of Eustachian Tube
AERA Pediatrics Registry
Prospective, multi-center, observational, real-world evidence data collection registry to confirm the continued clinical performance of the AERA® device in pediatric patients
- Trial name
- NCT07071298
- Where
- 9 sites in United States
- Volunteers
- 300 people
- Sponsor
- Integra LifeSciences Corporation
General Anesthesia
Gastric Ultrasound in Paediatric Anaesthesia
Anesthesia for emergency surgery is a situation at risk of pulmonary aspiration of gastric contents. It has been previously reported that bedside two-dimensional ultrasonography can be a useful tool for anesthesiologists to…
- Trial name
- ECHOGASTRO (NCT02584348)
- Testing
- Gastric ultrasound
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Hospices Civils de Lyon
Multiple Sclerosis, Relapsing-Remitting
Extension Study of BG00012 in Pediatric Subjects With Relapsing Remitting Multiple Sclerosis (RRMS)
The primary objective of the study is to evaluate the long-term safety of BG00012 in subjects who completed Study 109MS202 (NCT02410200).
- Trial name
- NCT02555215
- Testing
- dimethyl fumarate
- Where
- 12 sites in United States, Belgium and 8 more
- Volunteers
- 20 people
- Sponsor
- Biogen
Adverse Effects, Adverse Drug Event
How Safe Are Our Pediatric Emergency Departments?
Patient safety is an internationally recognized health care priority. Canadian data suggests that about 8% of adults admitted to hospital experience unintended harm (or 'adverse events') from the health care provided during their…
- Trial name
- NCT02162147
- Where
- 10 sites in Canada
- Volunteers
- 6,385 people
- Sponsor
- Children's Hospital of Eastern Ontario
Osteosarcoma
Losartan + Sunitinib in Treatment of Osteosarcoma
This study is a Phase 1/1b clinical trial that aims to determine the Maximally Tolerated Dose of Losartan and Sunitinib Combination Therapy.
- Trial name
- NCT03900793
- Testing
- Losartan, Sunitinib
- Where
- 4 sites in United States
- Volunteers
- 41 people
- Sponsor
- University of Colorado, Denver
Deformity, Genu Valgus
Stapling Versus 8plate for Correction of Genu Valgus
In children with excessive knock knees it may be necessary to use guided growth (small surgical procedure) so the child outgrows the condition before maturity.
- Trial name
- NCT01528553
- Testing
- 8plate, Staples (Richards, Smith & Nephew)
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Balloon Pulmonary Valvuloplasty in Pulmonary Valvular Stenosis
The Outcome of Percutaneous Balloon Pulmonary Valvuloplasty in Pediatrics
evaluation the outcome of percutaneous balloon pulmonary valvuloplasty in children with valvular pulmonary stenosis at the Pediatric Cardiology Unit.
- Trial name
- NCT05748431
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pain
Intranasal Fentanyl Versus Placebo for Catheterization During a Voiding Cystourethrogram in Children
The purpose of this study is to determine whether intranasal fentanyl is better than placebo at decreasing pain in children 4-8 years of age during urinary catheterization for a VCUG study.
- Trial name
- NCT00405444
- Testing
- Fentanyl, Sterile water
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- The Hospital for Sick Children
Quality of Hospital Care for Children
Improving the Quality of Paediatric Hospital Care in the Kyrgyz Republic
A cooperation agreement between the Ministry of Health (MOH) of Kyrgyz Republic and WHO-EURO was established, for the implementation of a WHO Project to improve the quality of pediatric care in the referral hospitals.
- Trial name
- NCT02001116
- Testing
- Quality Improvement intervention
- Where
- Kyrgyzstan
- Volunteers
- 4,626 people
- Sponsor
- WHO Collaborating Centre for Maternal and Child Health, Trieste
Childhood Solid Tumor, Childhood Lymphoma
Pembrolizumab in Combination With Decitabine and Hypofractionated Index Lesion Radiation in Pediatrics and Young Adults
This pilot study is designed to assess the safety, tolerability, and preliminary anti-tumor activity of the combination of pembrolizumab, decitabine and fixed-dose hypofractionated index site radiotherapy in pediatric and young…
- Conditions
- Childhood Solid Tumor, Childhood Lymphoma, Relapsed Cancer, Refractory Cancer
- Trial name
- NCT03445858
- Testing
- Pembrolizumab, Decitabine, Hypofractionated Index Site Radiation
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Asthma
Effects of Ciclesonide MDI 50mg/Day and 200mg/Day (Ex-Valve) Once-Daily on Growth in Children With Mild Persistent Asthma
The primary objective is to determine if CIC 50 mg/day or 200 mg/day (ex-valve) administered once daily in the morning is non-inferior to placebo with respect to growth velocity in children with mild persistent asthma following a…
- Trial name
- NCT00270348
- Testing
- ciclesonide
- Volunteers
- 450 people
- Sponsor
- Sanofi
Attention Deficit Disorder With Hyperactivity, Learning Disorders
Effects Of A Computerized Working Memory Training Program On Attention, Working Memory, And Academics, In Adolescents With Severe ADHD/LD
Our primary aim is to determine whether a computerized working memory (WM) training program will help students with severe learning and attention problems, in terms of improving their WM.
- Trial name
- NCT00930449
- Testing
- Cogmed Working Memory Training Program., Academy of Math, Special Education/Individualized Tutoring
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- The Hospital for Sick Children
Constipation
Magnetic Resonance Imaging in Paediatric Constipation
Constipation in children is a common problem. Managing these children is difficult, partly because they do not respond to laxatives and partly because their bowel problem cannot be defined.
- Trial name
- MAGIC (NCT03564249)
- Testing
- MiniCap
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Sleep Apnea Syndromes in Children
Paediatric Oximetry Algorithms - Normative Data Collection
To undertake normative data collection of existing clinical algorithms using existing oximetry technology.
- Trial name
- NCT03823326
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Hirschsprung Disease
Laparoscopic-Assisted Transanal Pull-Through for Hirschsprung Disease in Pediatric:Short and Intermediate Outcomes of Two Different Techniques
Compare the functional and surgical outcomes of laparoscopic-assisted Swenson-like (LASwL) and laparoscopic-assisted Soave (LASo) pull through in children with HD.
- Trial name
- NCT07186647
- Testing
- laparoscopic-assisted Swenson-like (LASwL), laparoscopic-assisted Soave (LASo)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Childhood Brain Tumor, Childhood Brain Tumors
The FLaME Cognitive Rehabilitation Study for Childhood Brain Tumour
Medical treatments have improved survival rates for children with brain tumours. However, most children experience long-term difficulties with 'cognition' (thinking skills such as memory and paying attention) and cognitive…
- Conditions
- Childhood Brain Tumor, Childhood Brain Tumors, Pediatric Brain Neoplasms, Pediatric Brain Tumor
- Trial name
- FLaME (NCT06770335)
- Testing
- THE FATIGUE, LEARNING, AND MEMORY ENRICHMENT (FLaME) INTERVENTION - Full intervention, THE FATIGUE, LEARNING, AND MEMORY ENRICHMENT (FLaME) INTERVENTION - Cognitive rehabilitation only
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
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