Clinical trials: Pelvic Organ Prolapse
Pelvic Organ Prolapse, Posterior Vaginal Wall Prolapse
Laparoscopic Fascial Duplication Plus Sacral Colpopexy in Posterior Vaginal Prolapse
A Randomized Clinical Trial on Laparoscopic Fascial posterior vaginal duplication with absorbable sutures plus sacral colpopexy mesh placement VS sacral colpopexy isolated for vaginal posterior prolapse
- Trial name
- NCT05252637
- Testing
- Laparoscopic Fascial Posterior Vagina Duplication
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Cardinale G. Panico
Postoperative Pelvic Organ Prolapse, Benign Hysterectomy
Vaginal Vault Suspension During Benign Hysterectomy. A Questionnaire and Register-based Study.
Female pelvic organ prolapse (POP) is characterized by lack of vaginal support which enables pelvic organs to bulge into the vaginal walls and sometimes protrude through the genital hiatus.
- Conditions
- Postoperative Pelvic Organ Prolapse, Benign Hysterectomy, Suspension
- Trial name
- NCT02859272
- Volunteers
- 11,000 people
- Sponsor
- Nykøbing Falster County Hospital
Vaginal Prolapse
Surgical Outcomes of Vaginal Prolapse Repair With Elevate
The purpose of this study is to evaluate outcomes in patients having vaginal prolapse repair with the Elevate prolapse repair kit and compare these outcomes to patients who had a repair with Prolift. .
- Trial name
- NCT01190618
- Where
- United States
- Volunteers
- 417 people
- Sponsor
- Larry Sirls
Pelvic Organ Prolapse
A Large Multi-Center Database of Women Who Have Had and Are Going to Have Surgical Correction of Their Pelvic Organ Prolapse Using the Gynecare Prolift System
retrospective and prospective data collection for a database. Patients will have had or are going to have a repair of their pelvic organ prolapse using the Gynecare mesh Prolift System
- Trial name
- NCT01134003
- Where
- United States
- Sponsor
- The Institute of Pelvic Medicine & Reconstructive Surgery, Allentown, Pennsylvania
Genitourinary Syndrome of Menopause (GSM)
Vaginal Platelet-Rich Plasma and Vaginal Histology in Genitourinary Syndrome of Menopause
This study evaluates whether subepithelial injection of autologous platelet-rich plasma (PRP) into the vaginal wall produces histological changes consistent with tissue regeneration in postmenopausal women with genitourinary…
- Trial name
- NCT07905820
- Testing
- Autologous Platelet-Rich Plasma (PRP), 0.9% sodium chloride (normal saline)
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- National and Kapodistrian University of Athens
Rectal Prolapse
TEM Assisted Perineal Rectopexy in Treatment of Rectal Prolapse
Curvilinear incision in the postanal space, through the intersphincteric plane, insertion of Proctoscope of TEM technique and dissection till sacral promontory, insertion of mesh between the rectum and sacrum, post anal repair…
- Trial name
- NCT02609555
- Testing
- TEM perineal rectopexy
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Mansoura University
Endometriosis, Pelvic Prolapse
Suspension of the Pelvic and Abdominal Organs During Minimally Invasive Surgery
The goal of this retrospective observational study is to evaluate the efficacy, safety, and practicality of an organ suspension technique with adjustable tension suture in facilitating minimally invasive gynecologic surgeries at…
- Conditions
- Endometriosis, Pelvic Prolapse, Endometrium Cancer
- Trial name
- NCT06187558
- Testing
- Pelvic and abdominal organ suspension technique
- Where
- Italy
- Volunteers
- 330 people
- Sponsor
- University of Cagliari
Pelvic Organ Prolapse
Alterations in Connective Tissue in Patients With or Without Pelvic Organ Prolapse
The aim of our study is to investigate the alterations in connective tissue of vaginal wall in patients with and without pelvic organ prolapse (POP).
- Trial name
- NCT01749696
- Where
- Finland
- Volunteers
- 78 people
- Sponsor
- Turku University Hospital
Pelvic Organ Prolapse
Measuring Abdominal Wall Compliance During Gynecologic Laparoscopic Surgery
To measure abdominal wall compliance (AWC) during gynaecologic laparoscopy and assess its relation to the pelvic organ prolapse quantification (POP-Q) score of the same individual, and determine a relationship if present.
- Trial name
- AbComp (NCT05012956)
- Testing
- Laparoscopic sacrocolpopexy, gynecologic laparoscopic surgery
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Rectal Prolapse
Laparoscopic Suture Versus Mesh Rectopexy for the Treatment of Persistent Complete Rectal Prolapse in Children
Purpose: to compare Laparoscopic mesh rectopexy with laparoscopic suture rectopexy The operative time, recurrence rate, post-operative constipation, and effect on fecal incontinence, were reported and evaluated for each group…
- Trial name
- NCT04117633
- Testing
- Laparoscopy
- Volunteers
- 64 people
- Sponsor
- Al-Azhar University
Pelvic Organ Prolapse
PEssary Plus Physiotherapy for Pelvic Organ Prolapse (PEPPY)
1. To determine the feasibility of conducting a randomised controlled trial (RCT) of the effectiveness of a PFMT intervention in conjunction with vaginal pessary management versus vaginal pessary management alone for women with…
- Trial name
- PEPPY (NCT01136889)
- Testing
- PFMT
- Where
- 4 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- Glasgow Caledonian University
Pelvic Floor Prolapse
The Effect of Intra-vaginal Conjugated Estrogen Cream on Ring Pessary Use for Pelvic Organ Prolapse
The primary purpose of this two-arm randomized clinical trial is to determine if in women desiring use of a pessary for pelvic organ prolapse (POP) and are successfully fit, if 1-year use and patient impression of improvement is…
- Trial name
- NCT04393194
- Testing
- Vaginal Cream with Applicator [Dose Form]
- Volunteers
- 420 people
- Sponsor
- Peking Union Medical College Hospital
Cystocele, Vaginal Vault Prolapse
Laser Therapy in Managing Vaginal Prolapse
Efficacy of laser therapy in postmenopausal women with symptomatic prolapse stage >1. Assessment tools will include prolapse stage quantification system (POP-Q) and validated condition related questionnaires.
- Conditions
- Cystocele, Vaginal Vault Prolapse, Rectocele, Enterocele
- Trial name
- NCT03714607
- Testing
- Erbium Yttrium Aluminum Garnet (Er:YAG) laser
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Rectal Prolapse
A Modified Technique to Facilitate Pealing of the Rectal Mucosa in Delorme Operation
The aim of this study is to evaluate the investigator new modification for delorme procedure in patients with rectal prolapse , assessing intra-operative morbidity and recurrence rate .
- Trial name
- NCT02901210
- Testing
- Modified delorme procedure
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yasser Mohamed Abdel-samii
Pelvic Organ Prolapse
Comparison of Sacrospinous Ligament Fixation and Uterosacral Ligament Suspension for Apical Prolapse Surgery: A Randomized Clinical Trial
the main aim of this study is to study the anatomical and functional outcomes of two vaginal apical fixation procedures; sacrospinous ligament fixation and uterosacral ligament suspension, for pelvic organ prolapse surgery.
- Trial name
- NCT05668130
- Testing
- Sacrospinous ligament fixation, Uterosacral Ligament Suspension
- Volunteers
- 194 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Pelvic Organ Prolapse
Benefits of Peri-surgical Physical Therapy in the Management of III and IV Grades of Pelvic Organ Prolapse
To find out the effectiveness of physical therapy associated with the surgical treatment over the simptoms and quality of life in III and IV grades of pelvic organ prolapse, patients will be randomly assigned to one of these…
- Trial name
- NCT02846480
- Testing
- physical therapy, surgical treatment, behavior therapy
- Volunteers
- 65 people
- Sponsor
- BEATRIZ SANCHEZ SANCHEZ
Postoperative Complications
Comparison Between Two Types of Meshes Used in Pelvic Organs Prolapse Procedures
Using partially absorbed meshes in pelvic reconstructive surgery will involve fewer postoperative complications especially less pain caused by the mesh mass.
- Trial name
- NCT01645020
- Where
- Israel
- Volunteers
- 240 people
- Sponsor
- Western Galilee Hospital-Nahariya
Pelvic Organ Prolapse Vaginal Surgery, Stress Urinary Incontinence in Women
The AMPER Study: Evaluation of the Efficacy of Human Amniotic Membrane Grafting in Preventing Mesh Exposure in Vaginal Reconstructive Surgery Using Polypropylene Mesh.
This study evaluates the efficacy of adding a human amniotic membrane graft to polypropylene mesh surgery for pelvic prolapse and stress urinary incontinence.
- Trial name
- AMPER (NCT07414849)
- Testing
- Sacrospinous Hysteropexy with Mesh, Retropubic Mid-urethral Sling (Bottom-Up), Transobturator Mid-urethral Sling (Out-In)
- Where
- Argentina
- Volunteers
- 330 people
- Sponsor
- Hospital General de Agudos J. M. Penna
Pelvic Organ Prolapse
The Efficacy of Transcutaneous Electrical Nerve Stimulation on LUTS: One Prospective Study.
The study is a prospective study at a single institution. Investigators create strict inclusion and exclusion criteria, selecting 126 patients who undergo the pelvic reconstructive surgery.
- Trial name
- NCT03634722
- Testing
- PHENIX4-8-8 PLUS
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Peking University People's Hospital
Pelvic Organ Prolapse
A Feasibility Study on the Value of Pelvic Floor Training After Pelvic Organ Prolapse Surgery
The main objective is to assess the feasibility of a randomized controlled trial that investigates the effects of pelvic floor training on recurrence in pelvic organ prolapse surgeries.
- Trial name
- NCT04539782
- Testing
- Physiotherapy intervention
- Where
- Iceland
- Volunteers
- 50 people
- Sponsor
- Landspitali University Hospital