Clinical trials: Percutaneous Nephrolithotomy (PCNL)
Kidney Stone
Comparison of Efficacy of Intercostal Nerve Block vs Peritract Infiltration With 0.25% Bupivacaine in PCNL
Percutaneous nephrolithotomy (PCNL) is the preferred treatment for renal stones >2 cm or resistant to ESWL. Postoperative pain following this invasive surgery adds to the morbidity of patient which requires additional analgesia…
- Trial name
- NCT04835922
- Testing
- Intercostal Nerve Block, Peritract Infiltration
- Where
- Nepal
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Nephrolithiasis, Urinary Tract Infection (UTI)
Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2
This study will be a multi-institutional randomized clinical trial of a short course of pre-operative antibiotic prophylaxis in addition to perioperative antibiotics prior to undergoing percutaneous nephrolithotomy.
- Conditions
- Nephrolithiasis, Urinary Tract Infection (UTI), Sepsis
- Trial name
- PNLABXPART2 (NCT02829060)
- Testing
- Nitrofurantoin 100 MG, 7d, Gentamicin, 5mg/kg, Ampicillin 2g
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- University of California, San Diego
Renal Stone, Percutaneous
Erector Spinae Versus Paravertebral in Pediatric PCNL
To compare the efficacy of ultrasound-guided erector spinae plane block versus ultrasound-guided paravertebral block in pediatric patients undergoing percutaneous nephrolithotomy
- Conditions
- Renal Stone, Percutaneous, Nephrolithotomy
- Trial name
- NCT05589649
- Testing
- Erector spinae plane block, Paravertebral block
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Assiut University
Urolithiasis, Percutaneous Nephrolithotomy (PCNL)
A Multifunctional Miniature Nephroscope for Percutaneous Nephrolithotomy
The goal of this clinical trial is to introduce a novel multifunctional miniature endoscopic system, namely "Aircraft Nephroscope", for percutaneous nephrolithotomy (PCNL) to treat the patients with urolithiasis.
- Trial name
- NCT07471711
- Testing
- percutaneous nephrolithotomy
- Where
- China
- Volunteers
- 216 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Renal Stones, Urolithiasis, Calcium Oxalate
Comparison of Trifecta Analysis of Standard Versus Mini Percutaneous Nephrolithotomy in the Management of Urolithiasis
Introduction: Urolithiasis is a common urological condition, and percutaneous nephrolithotomy (PCNL) is a widely used treatment option.
- Trial name
- Trifecta (NCT06836700)
- Testing
- Mini PCNL
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Nephrolithiasis, Pediatric Nephrolithiasis
Tubeless vs Tube PCNL in Pediatric Nephrolithiasis
This study is designed to compare two surgical techniques for removing kidney stones in children and adolescents (ages 6-18 years).
- Trial name
- TUBELESS (NCT07183930)
- Testing
- Tubeless Percutaneous Nephrolithotomy (PCNL), Standard Tube Percutaneous Nephrolithotomy (PCNL)
- Where
- Pakistan
- Volunteers
- 640 people
- Sponsor
- Lady Reading Hospital, Pakistan
Urolithiasis
F-URS and Mini PCNL for Pediatric Urolithiasis
To compare RIRS versus mini-perc PNL in the management of medium size pediatric renal stones (10-20 mm) through a RCT.
- Trial name
- NCT06571617
- Testing
- Mini PCNL (mini percutaneous nephrolithotomy), RIRS (retrograde intrarenal surgery/ flexible URS)
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Mansoura University
Kidney Stone
A Prospective Observational Comparison of SMP and ESWL for the Treatment of Renal Stones ≥20 mm in Children (IAU-04)
ESWL and PNL are the two treatment modalities for kidney stones greater than 20 mm in the pediatric population. ESWL is non-invasive, does not require anesthesia and inexpensive, but its success rate may be lower, and require…
- Trial name
- NCT04317443
- Testing
- Super-mini percutaneous nephrolithotomy (SMP), Extracorporeal Shock Wave Lithotripsy (ESWL)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The International Alliance of Urolithiasis
Kidney Calculi (or Renal Calculi / Nephrolithiasis), Supine Mini Percutaneous Nephrolithotomy
Supine vs. Prone Mini-PCNL in Children
Percutaneous nephrolithotomy (PCNL) is an established intervention for large or ESWL-resistant renal stones in pediatric populations.
- Conditions
- Kidney Calculi (or Renal Calculi / Nephrolithiasis), Supine Mini Percutaneous Nephrolithotomy, Prone Mini Percutaneous Nephrolithotomy
- Trial name
- SUPRO-PED (NCT07887945)
- Testing
- Group A, Group B
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Fayoum University Hospital
Renal Stones, Calculus
Comparison of ESWL and Mini-PCNL for High-Density Renal Stones in Children
Pediatric nephrolithiasis is an increasing health problem, with rising prevalence particularly in certain geographic regions. Management options for pediatric renal stones include extracorporeal shockwave lithotripsy (SWL)…
- Conditions
- Renal Stones, Calculus, Pediatric, Endoscopy
- Trial name
- NCT07360041
- Testing
- Miniaturized Percutaneous Nephrolithotomy (mini-PNL), Shock Wave Lithotripsy (SWL)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Calculi, Renal, PCNL
Preoperative Prophylactic Fosfomycin Trometamol Versus 5-day Levofloxacin in Prevention of Postpercutaneous Nephrolithotomy Infectious Complications and Sepsis.
A randomized controlled trial comparing the use of preoperative prophylactic single dose fosfomycin trometamol versus levofloxacin in prevention of post-PCNL infectious complications and sepsis.
- Conditions
- Calculi, Renal, PCNL, Infectious Complications
- Trial name
- NCT07355907
- Testing
- PCNL
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Tanta University
Stone, Kidney, Lithiasis Renal
Standard-PCNL vs Mini-PCNL vs Super-mini PCNL for the Treatment of ≥2 cm Renal Stone
Background: Standard-PCNL was considered as the first choice for ≥2 cm renal stones. Miniaturized technique Mini-PCNL has also been implicated in the past two decades.
- Conditions
- Stone, Kidney, Lithiasis Renal, Surgery
- Trial name
- NCT03771365
- Testing
- Standard-PCNL, Mini-PCNL, SMP
- Volunteers
- 3,000 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Nephrolithiasis, Kidney Calculi
Comparison Between Supine Mini-PCNL and Flexible Ureteroscopy (FURS) for Dense Lower Calyceal Stones (1-2 cm) in School-Age Pediatric Patients
This randomized controlled clinical study compared supine mini percutaneous nephrolithotomy versus flexible ureteroscopy for the management of dense lower calyceal renal stones measuring 1-2 centimeters (≤20 millimeters) with…
- Conditions
- Nephrolithiasis, Kidney Calculi, Urolithiasis
- Trial name
- NCT07345234
- Testing
- Supine Mini Percutaneous Nephrolithotomy, Flexible Ureteroscopy
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Kidney Stones
Feasibility of Radiation-Free Percutaneus Nephrolithotomy for Kidney Stones
The goal of this observational study is to investigate the feasibility of ultrasound-guided percutaneus nephrolithotomy in patients with kidney stones.
- Trial name
- PCNL (NCT06922006)
- Testing
- Percutaneus nephrolithotomy (PCNL)
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of California, San Diego
Nephrolithiasis
The Success of Pediatric Percutaneous Nephrolithotomy
Between June 1997-June 2018, 573 pediatric patients underwent PCNL for renal stone disease by senior surgeons. Data was disunited into 2 groups.
- Trial name
- NCT04299204
- Testing
- Percutaneous nephrolitotomy
- Volunteers
- 553 people
- Sponsor
- Osmaniye Government Hospital
Kidney Stone
Trial of Efficacy of the RetroPerc Device
The purpose of this study is to determine the efficacy of RetroPerc® in obtaining renal access for percutaneous nephrolithotomy
- Trial name
- NCT05022537
- Testing
- retrograde nephrostomy, antegrade nephrostomy
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Kidney Stones, Percutaneous Nephrolithotomy
Paravertebral Versus Caudal Block in Pediatric PCNL
To compare the efficacy of Ultrasound guided thoracic paravertebral block versus ultrasound guided caudal epidural block in pediatric patients undergoing percutaneous nephrolithotomy
- Trial name
- NCT05012215
- Testing
- Paravertebral, Caudal block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Upper Urinary Tract Stones
Role of Nephrolithometric Scoring Systems in Prediction of PCNL Outcomes in Adult
Prospective study is to compare between different nephrolithometric scoring systems in prediction of PCNL outcomes in terms of efficacy , success rate and safety in Adult patients with UUT stones unilateral or bilateral, single…
- Trial name
- NCT04158570
- Testing
- Percutaneous Nephrolithotomy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University