Clinical trials: Peri-Implantitis
Periodontitis, Periimplantitis
PPAR, RXR, and VDR Expressions in Peri-implantitis
ABSTRACT Objective: Periodontitis and peri-implantitis are the irreversible destructive diseases of the periodontal and peri-implant tissues.
- Trial name
- NCT04020146
- Testing
- Gingival biopsies
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Periimplantitis, Peri-implant Mucositis
The Effect of Peri-implant Surgery and Chair-side Supportive Post Surgical Peri-implant Therapy
Peri-implantitis is defined as inflammation in the mucosa surrounding an oral implant with loss of supporting bone. The goals of peri-implantitis treatment are to resolve inflammation and to arrest the progression of disease.
- Trial name
- NCT03421717
- Testing
- Chitosan brush
- Volunteers
- 46 people
- Sponsor
- University of Oslo
Implant Tissue Failure, Dental Implant Failed
Laterally Rotated Flap for Soft Tissue Augmentation Around Maxillary Loaded Osseointegrated Dental Implant
Peri-implant mucositis is one of the most common peri-implant diseases. It was reported in more than 20% of the subjects rehabilitated with dental implants (Lee et al. 2017; Rodrigo et al. 2018; Wada et al. 2019).
- Conditions
- Implant Tissue Failure, Dental Implant Failed, Peri-Implantitis
- Trial name
- NCT06206499
- Testing
- soft tissue augmentation
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Bone Resorption, Diabetes
Application of Information-Motivation-Behavioral Model-based Continuity of Care on the Peri-implantitis Recovery in Diabetic Implant Overdenture Patients
The investigators recruited 32 diabetic IOD patients with a total of 110 problematic implants who had completed the treatment for peri-implantitis between January 2021 and March 2023 as research subjects.
- Trial name
- NCT06103799
- Testing
- IMB model-based continuity of care
- Where
- China
- Volunteers
- 32 people
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Peri-implant Mucositis, Peri-Implantitis
Metabolomic and Proteomic Fingerprinting in Peri-implant Diseases
Due to the limited efficacy of its treatment modalities, there is a stringent need to improve the prevention and early diagnosis of peri-implantitis.
- Trial name
- NCT04283903
- Testing
- PICF
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Universidad Complutense de Madrid
Peri-implantitis, Peri-implant Bone Loss
Access to Probing and Peri-implant Diseases
This multicenter cross-sectional study aims to evaluate the association between access to peri-implant probing and radiographic peri-implant bone loss.
- Trial name
- NCT07557459
- Testing
- Peri-implant probing
- Where
- 9 sites in Spain
- Volunteers
- 281 people
- Sponsor
- Arrow Development
Peri-Implantitis
Ten Years Follow up of Peri-implant Surgery
To report 10-years follow up of patients following the surgical treatment of peri-implantitis and to identify possible risk indicators for the progression of disease during supportive peri-implant therapy.
- Trial name
- NCT04254406
- Testing
- Descriptive study
- Where
- Sweden
- Volunteers
- 41 people
- Sponsor
- Public Dental Service, Specialist Clinics, Sweden
Peri-Implantitis
Locally Delivered 1% Metformin Gel in Peri-implantitis
This study evaluates the efficacy of 1% local metformin gel in deep periimplant pockets of type 2 diabetes mellitus patients. Half of the participants will receive 1% metformin gel with manual debridement while the other half…
- Trial name
- NCT03312582
- Testing
- 1% local metformin gel
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- King Saud University
Peri-Implantitis
Therapeutic Peri-implant Maintenance with Laser Therapy
The present study represents an extension of the previously concluded randomized clinical trial "Laser-Assisted Regenerative Surgical Therapy for Peri-implantitis" (HUM00124386).
- Trial name
- NCT04251793
- Testing
- Observation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Michigan
Atherosclerosis, Endothelial Dysfunction
Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Peri-implantitis and Peri-implant Mucositis
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment on endothelial dysfunction parameters in subjects with peri-implantitis/peri-implant mucositis…
- Conditions
- Atherosclerosis, Endothelial Dysfunction, Peri-Implantitis, Peri-implant Mucositis
- Trial name
- NCT05906810
- Testing
- Non-surgical periodontal treatment
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Catania
Peri-implantitis
20-25 Year Follow-Up on Regenerative Bone Procedures for Peri-Implantitis
The goal of this 20-25-year observational study is to investigate the outcomes of bone regenerative surgery in peri-implantitis.
- Trial name
- periimpl20y (NCT06648564)
- Testing
- Bone regenerative surgery with a bone graft substitute and a resorbable membrane
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Kristianstad University
Peri-Implantitis
The Morphology of the Peri-Implantitis Defects: A Cone-Beam Computed Analysis
To study the morphology of the peri-implant defects using cone-beam computed tomography based on a priori case definition of peri-implantitis (≥3mm of radiographic bone loss + inflammatory clinical parameters) Diagnosis of…
- Trial name
- NCT03777449
- Testing
- CBCT
- Where
- Spain
- Volunteers
- 47 people
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Peri-implantitis
Long-term Stability of Peri-implantitis Treatments: a 3-year Clinical Evaluation
This prospective study will include patients previously enrolled in the PER-ECL-2019-05 trial who attend the Department of Periodontology (CUO) for maintenance therapy or treatment of periodontal and/or peri-implant diseases…
- Trial name
- NCT07208643
- Where
- 2 sites in Spain
- Volunteers
- 27 people
- Sponsor
- Ramón Pons Calabuig
Peri-implant Mucositis, Peri-Implantitis
The Effect of Different Dental Implant Surface Characteristics on Immunological and Microbiological Parameters
Objectives: To assess the levels of TNF-α, PGE2, RANKL, RANK, OPG, which are immunological markers of peri-implant disease and F. nucleatum, P. gingivalis, T. denticola, T. forsythia, P. intermedia, S.
- Trial name
- NCT03693196
- Testing
- PICF, Perio-paper®, Subgingival Plaque, Hu-Friedy®, Williams probe, PCPNU-15 Hu-Friedy®
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Dental Implants, Periimplantitis
Long-term Examination of Titanium Dental Implants With a TPS Surface: A Prospective 20-year Case Series Study
Since 1986, newly developed titanium implants with a TPS surface have been utilized for the treatment of partially edentulous patients with implant supported fixed dental prostheses (FTP).
- Trial name
- NCT00921583
- Testing
- Long-term examination
- Where
- Switzerland
- Volunteers
- 67 people
- Sponsor
- University of Bern
Peri-Implantitis
Analysis of Genetic Variations in Patients With Peri-implantitis
The primary objective of this study is to evaluate interleukin-1(IL-1) gene group polymorphisms in patients with peri-implantitis and to compare them with patients with peri-implant health (control group), taking into account…
- Trial name
- NCT04807725
- Testing
- Analysis of genetic polymorphisms, Biochemical analysis
- Where
- Portugal
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Peri-Implantitis
Peri-implantitis and MMP-8
Peri-implantitis is defined as the pathological condition around dental implants characterized by inflammation in the peri-implant mucosa and progressive bone loss, eventually leading to implant loss.
- Trial name
- NCT05711407
- Testing
- Gene Polymorphisms of MMP-8
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Periodontal Diseases, Peri-implantitis
Implant Surface Decontamination With 2 % Chlorhexidine in Peri-implantitis Treatment
Peri-implantitis is a infectious disease that resides in the mucosa surrounding dental implants and also affects the supporting bone.
- Trial name
- NCT01852253
- Testing
- 2% chlorhexidine, 0.12% chlorhexidine
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- University Medical Center Groningen
Peri-Implantitis
Peri-implantitis in HIV-positive Patients
Objectives: This study aimed to assess the prevalence of peri-implantitis in human im-munodeficiency virus (HIV) -positive patients and the presence of a possible correlation between the immunological profile and serological…
- Trial name
- PERIHIV2 (NCT04829968)
- Testing
- gingival conditions control
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- Università Vita-Salute San Raffaele
Peri-implantitis, Dental Implant Complications
Analysis of the Factors Influencing the Occurrence of Peri-implant Inflammation in Patients With Oral Implant Repair and Study on the Maintenance Effect of Subgingival Sandblasting
Abstract Objective The purpose of this study was to analyze the factors affecting the occurrence of peri-implant inflammation in patients with oral implant repair, and to explore the effect of subgingival sandblasting technology…
- Conditions
- Peri-implantitis, Dental Implant Complications, Periodontal Inflammation, Gingival Diseases
- Trial name
- NCT06998160
- Testing
- glycine subgingival sandblasting group and erythritol subgingival sandblasting group, control group
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Hui Xie