Clinical trials: Periodontal Surgery
Gingival Recession
Platelet Rich Fibrin in the Treatment of Palatal Wounds
In this study it will be investigated the usefulness of Platelet-Rich Fibrin (PRF) on in the epithelialized connective tissue graft palatal donor site healing acceleration and in the patient's morbidity reduction.
- Trial name
- NCT02438046
- Testing
- Palatal wound bandage
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Staining Effect of Chlorhexidine
Spectrophotometric Evaluation of Chlorhexidine Pigmentations After Oral Surgery: a Prospective Randomized Clinical Trial
The aim of this clinical trial was to evaluate through a clinical spectrophotometric analysis the staining side effect of a 0.2% CHX mouthwash containing an anti discoloration system (ADS) compared with a 0.12% and a 0.2% CHX…
- Trial name
- NCT02132546
- Testing
- Chlorhexidine
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- dott. Lorenzo Bevilacqua
Periapical Disease
Effect of Piezoelectric Surgery on Quality of Life and Periradicular Healing After Endodontic Surgery
This study will compare the effect of piezo Vs bur on quality of life and healing after endodontic surgery.
- Trial name
- NCT04358887
- Testing
- piezoelectric surgery, conventional bur
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis
Non-Surgical Treatment of Periodontitis With Adjunctive Sodium Hypochlorite/Amino Acids and Cross-Linked Hyaluronic Acid
The goal of this clinical trial is to learn if using sodium hypochlorite/amino acid gel, with or without cross-linked hyaluronic acid, as an addition to standard non-surgical periodontal therapy works to treat periodontitis in…
- Trial name
- NCT07474272
- Testing
- Standard Non-Surgical Periodontal Therapy, tandard Therapy + Sodium Hypochlorite/Amino Acid Gel, Standard Therapy + Sodium Hypochlorite/Amino Acid Gel + Cross-Linked Hyaluronic Acid
- Where
- Lebanon
- Volunteers
- 78 people
- Sponsor
- Marwan El Mobadder
Periimplantitis, Peri-implant Mucositis
The Effect of Peri-implant Surgery and Chair-side Supportive Post Surgical Peri-implant Therapy
Peri-implantitis is defined as inflammation in the mucosa surrounding an oral implant with loss of supporting bone. The goals of peri-implantitis treatment are to resolve inflammation and to arrest the progression of disease.
- Trial name
- NCT03421717
- Testing
- Chitosan brush
- Volunteers
- 46 people
- Sponsor
- University of Oslo
Periodontal Diseases
Antimicrobial Photodynamic Therapy as an Adjunct Treatment for Periodontal Disease in Down's Syndrome Patients
The aim of this study was to evaluate the effectiveness of antimicrobial photodynamic therapy as an adjuvant of scaling and root planning for treatment of periodontal disease in patients with Down's Syndrome.
- Trial name
- NCT02938988
- Testing
- Antimicrobial photodynamic therapy, Scaling and root planning, red laser
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- University of Sao Paulo
Thalassemia Major, Chronic Periodontitis
Periodontal Therapy in Thalassemia Major Patients
The study aims to evaluate the effect of local non surgical periodontal therapy on the systemic pro-inflammatory markers in the β-thalassemia (TM-β) patients with chronic periodontitis and systemically healthy demographically…
- Trial name
- NCT03311243
- Testing
- Non surgical periodontal therapy, Chemical plaque control
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- King Saud University
Periodontitis, Periodontal Regeneration, Clinical and Radiographic Results, Modified Minimal Invasive Surgery
Endoscope-assisted Flapless Approach Versus Papillary Preservation Technique in Periodontal Regeneration.
The standard of care for regeneration of lost periodontal tissue from disease at contained defect sites non-responding to non-surgical periodontal therapy is periodontal regenerative surgery.
- Conditions
- Periodontitis, Periodontal Regeneration, Clinical and Radiographic Results, Modified Minimal Invasive Surgery, Periodontal Regeneration
- Trial name
- EAFAR (NCT06978036)
- Testing
- Flapless periodontal regeneration with EMD + EASD, Periodontal regeneration with EMD + PPT
- Where
- Hong Kong
- Volunteers
- 56 people
- Sponsor
- The University of Hong Kong
Furcation Defects, Open Flap Debridement
Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement.
The reduced rate of success experienced in the treatment of Furcation involvement (FI) seems to result from the incomplete removal of subgingival plaque and calculus in the interradicular area owing to the peculiar anatomy of the…
- Conditions
- Furcation Defects, Open Flap Debridement, Periodontal Diseases
- Trial name
- NCT06025955
- Testing
- minimally invasive non- surgical therapy, open flap debridement
- Where
- India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Endodontic Infection, Periapical Diseases
The Effect of Different Hemostatic Agents on Hemorrhage Control, Pain and Quality of Life After Endodontic Microsurgery.
Background This randomized clinical trial evaluated the effect of two different hemostatic materials for endodontic microsurgery on bleeding control, postoperative pain and patients' quality of life.
- Trial name
- NCT07311291
- Testing
- Hemostatic Agent 1: Surgical glue (IfaBond, Dipromed, Italy), Hemostatic Agent 2: Ferric sulfate
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- University of Turin, Italy
Heart Transplant, Periodontitis
Effect of Non-Surgical Periodontal Therapy on Inflammation in Heart Transplant Recipients
Heart transplant recipients frequently exhibit chronic low-grade systemic inflammation, which can contribute to allograft dysfunction and cardiovascular complications.
- Conditions
- Heart Transplant, Periodontitis, Gingivitis, Systemic Inflammation
- Trial name
- NCT07791927
- Testing
- Full-mouth periodontal debridement
- Volunteers
- 20 people
- Sponsor
- Baskent University
Periodontitis
Effect of Menstrual Cycle Phase on Pain Perception and Anxiety During Non-Surgical Periodontal Treatment
This study evaluates the effect of menstrual cycle phases on pain perception and dental anxiety during non-surgical periodontal therapy in premenopausal women with Stage II and III periodontitis.
- Trial name
- MAPP (NCT07719686)
- Testing
- Non Surgical Periodontal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Karadeniz Technical University
Periodontitis
Efficacy of Curcumin Gel Combined With Non-surgical Periodontal Therapy on Salivary Procalcitonin Level in the Treatment of Periodontitis Patients
Objectives: To evaluate the efficacy of curcumin gel as an adjunct to scaling and root planing (SRP) on the salivary procalcitonin level in the treatment of periodontitis.
- Trial name
- NCT05667376
- Testing
- Local drug delivery, curcumin gel
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Reham abdelfatah
Diabetes Mellitus Type 2 With Hyperglycemia, Periodontitis
Vitamin C as an Adjunct in Periodontal Treatment in Type 2 Diabetes Mellitus Patients
Periodontitis patients with uncontrolled type 2 diabetes mellitus will receive non-surgical periodontal treatment and then be supplemented with daily 500 mg vitamin C (test group) or placebo (control group) for 2 months.
- Trial name
- NCT03269799
- Testing
- Vitamin C 500 MG Oral Capsule
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Periapical Periodontitis, Periradicular Lesion
Accuracy and Healing Outcomes of Endodontic Surgery Using a Static Surgical Guide.
The goal of this clinical trial is to evaluate the surgical accuracy and healing outcomes of endodontic surgery performed with the assistance of a 3D-printed static surgical guide in patients requiring apicoectomy.
- Conditions
- Periapical Periodontitis, Periradicular Lesion, Endodontic Treatment Failure, Postoperative Wound Healing
- Trial name
- NCT07734987
- Testing
- 3D-Printed Static Surgical Guide and Trephine Bur, Ultrasonic Retrograde Preparation and Bioceramic Retrograde Obturation
- Where
- Vietnam
- Volunteers
- 11 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Peri-Implantitis
Ten Years Follow up of Peri-implant Surgery
To report 10-years follow up of patients following the surgical treatment of peri-implantitis and to identify possible risk indicators for the progression of disease during supportive peri-implant therapy.
- Trial name
- NCT04254406
- Testing
- Descriptive study
- Where
- Sweden
- Volunteers
- 41 people
- Sponsor
- Public Dental Service, Specialist Clinics, Sweden
Non-surgical Periodontal Therapy
PRF + Minocycline vs Arestin in Non-surgical Perio Therapy
Periodontitis is a chronic, biofilm-modulated inflammatory disease characterized by microbial dysbiosis and a dysregulated host immune response, eventually resulting in the gradual breakdown of the periodontal attachment…
- Trial name
- NCT07437209
- Testing
- Arestin, PRF + M
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Center for Advanced Rejuvenation and Esthetics
Periodontitis
Conservative Surgery with Modified Widman Flap Vs Papilla Preservation Technique for the Treatment of Residual Pockets
The primary aim of the study is to evaluate the efficacy of conservative surgery with or without papilla preservation technique in the treatment of deep residual pockets ≥ 6 mm in stage III-IV periodontitis patients after cause…
- Trial name
- MWF vs PPT (NCT06661928)
- Testing
- Papilla preservation flap, Widman flap procedure
- Volunteers
- 80 people
- Sponsor
- University of Turin, Italy
Periodontitis
Evaluation of the Systemic Burden of Non-surgical Periodontal Therapy: A Randomized Clinical Trial on Five Different Treatment Protocols
Periodontitis is a chronic inflammatory disease of the periodontal tissues leading to the destruction of the tooth supporting structures.
- Trial name
- NCT07077122
- Testing
- Scaling and Root Planing, antibiotic prophylaxis, 810nm Diode Laser
- Where
- Greece
- Volunteers
- 75 people
- Sponsor
- National and Kapodistrian University of Athens
Periodontal Diseases
Graphene Oxide in the Surgical Management of Intrabony Periodontal Defects
Using Graphene oxide in the surgical management of periodontal intrabony defects.
- Trial name
- NCT05341245
- Testing
- Graphene oxide and open flap debridement, Open flap debridement
- Volunteers
- 6 people
- Sponsor
- Ain Shams University