Clinical trials: Peripheral Arterial
Cardiovascular Diseases, Peripheral Vascular Diseases
Etiology and Prevalence of Peripheral Arterial Disease
To determine the prevalence of peripheral arterial disease in a defined population by non-invasive techniques; to evaluate the association of cardiovascular disease risk factors with peripheral vascular disease; to determine…
- Conditions
- Cardiovascular Diseases, Peripheral Vascular Diseases, Arterial Occlusive Diseases
- Trial name
- NCT00005142
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Peripheral Artery Disease
Genetics of Peripheral Artery Genomics
Peripheral artery disease is a disease that contributes to significant morbidity and mortality of millions of Americans yearly. Very little is known about the pathophysiology of atherosclerosis in peripheral artery disease.
- Trial name
- NCT00615121
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Duke University
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Critical Limb Ischemia
Study to Explore the Effect of Lowering Blood Viscosity in Patients With Treatment-resistant Critical Limb Ischemia
PAD is caused by an increased flow resistance in atherosclerotic ischemic limbs. The investigators hypothesize that reducing blood viscosity (through controlled phlebotomy), thereby increasing the deformability of red blood…
- Trial name
- CLI-PH (NCT01758874)
- Testing
- phlebotomy
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul Veterans Hospital
Peripheral Arterial Disease
Outcomes of Endovascular Treatment of Superficial Femoral Artery In-stent Restenosis
Lower limb peripheral arterial disease (PAD) is a common, important manifestation of systemic atherosclerosis. Stenosis or occlusions in the superficial femoral artery (SFA) may result in intermittent claudication or even…
- Trial name
- NCT04123639
- Testing
- PTA
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cancer
Hepatic Arterial Infusion of Melphalan With Hepatic Perfusion in Treating Patients With Unresectable Liver Cancer
RATIONALE: Hepatic arterial infusion uses a catheter to deliver anticancer substances directly into the liver. Drugs used in chemotherapy, such as melphalan, work in different ways to stop tumor cells from dividing so they stop…
- Trial name
- NCT00096083
- Testing
- isolated perfusion, melphalan
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Delcath Systems Inc.
Intermittent Claudication
Cross-sectoral Rehabilitation for Patients With Intermittent Claudication
Exercise training combined with other lifestyle changes are essential elements in conservative management of patients with Intermittent Claudication (IC).
- Trial name
- NCT03730623
- Testing
- Supervised exercise training
- Where
- Denmark
- Volunteers
- 118 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Arterial Blood Pressure, Difficult Vein Access
Comparison of Traditional and Ultrasound-Guided Techniques for Vascular Access in Patients With Difficult Venous Access in Emergency Department.
The aim of this clinical trial is to compare the use of ultrasound versus the traditional palpation and visualization technique for vascular punctures, both peripheral venous and arterial punctures for arterial blood gas…
- Trial name
- PUVASECO (NCT07013994)
- Testing
- peripheral venous cannulation with ultrasound-guided technique, Arterial gas puncture using ultrasound-guided technique, Peripheral venous cannulation with traditional technique
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Mercedes Segunda Peralta Gámez
Limping
High Resolution IR Imaging for Diagnosis in the Acute Limping Child - ThermLimp
A variety of different diseases may cause a limp in a child, and in younger children it is particularly challenging to isolate the area affected.
- Trial name
- Thermlimp (NCT03312348)
- Testing
- Infrared imaging
- Volunteers
- 30 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Air or Gas Embolism, Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy Registry
The purpose of the Hyperbaric Oxygen Therapy Registry (HBOTR) is to provide real world patient outcome and side effect information from electronic health records submitted to a specialty specific hyperbaric registry as part of…
- Conditions
- Air or Gas Embolism, Carbon Monoxide Poisoning, Clostridial Myositis and Myonecrosis (Gas Gangrene), Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemias
- Trial name
- HBOTR (NCT02483650)
- Volunteers
- 5,000 people
- Sponsor
- U.S. Wound Registry
Critical Limb Ischemia, Peripheral Arterial Occlusive Disease
Cryoplasty CLIMB-registry
In 5 Belgian hospitals, the data of 100 CLI-patients receiving the cryoplasty technique to treat their infrapopliteal arterial lesions will be collected.
- Trial name
- CLIMB (NCT00459888)
- Testing
- PolarCath Peripheral Dilatation System (Boston Scientific)
- Where
- 4 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Flanders Medical Research Program
Intermittent Claudication
(Cost) Effectiveness Study of Exercise Therapy in Patients With Peripheral Arterial Disease
The purpose of this study is to determine if supervised exercise therapy in a physiotherapeutic setting, with or without therapy feedback, is more (cost-)effective than exercise therapy based on a 'go home and walk' advice…
- Trial name
- EXITPAD (NCT00279994)
- Testing
- Exercise therapy, Accelerometer (PAM; Personal Activity Monitor), Oral Exercise Therapy advise
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Atrium Medical Center
Postoperative Hemorrhage
Neptune Pad ® Compared to Conventional Manual Compression
BACKGROUND. Arterial access site complications remain the most frequent adverse events after percutaneous transluminal procedures.
- Trial name
- NCT00597363
- Testing
- Neptune P.A.D. (R), conventional manual compression
- Where
- Austria
- Volunteers
- 201 people
- Sponsor
- Vienna General Hospital
Peripheral Vascular Disease
Oslo Balloon Angioplasty Versus Conservative Treatment
Background: Percutaneous transluminal angioplasty (PTA) has been popularized as a simple, effective and cheap treatment achieving 50-70% symptomatic patency rates in patients with peripheral occlusive disease..
- Trial name
- NCT00222196
- Testing
- lifestyle, PTA
- Volunteers
- 200 people
- Sponsor
- Ullevaal University Hospital
Peripheral Artery Disease
Implementation of Vascular Care Team to Improve Medical Management of PAD Patients
This study intends to evaluate the efficacy of a multidisciplinary vascular care team utilizing an intensive guideline-based lipid reduction program in improving risk factor modification as measured by LDL-C reduction at 12…
- Trial name
- NCT04400409
- Testing
- Intervention A - Vascular Care + site 6MWT administration, Intervention B - Standard Care + site 6MWT administration, Intervention A - Vascular Care + CPC EQuIP 6MWT administration
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Colorado Prevention Center
Peripheral Arterial Disease
Exercise on Expression of Heat Shock Protein 70 in Arterial Risk
Introduction: Atherosclerotic Peripheral Arterial Disease (PAD) is the leading cause of mortality in the western world. To maintain homeostasis of the vessel wall, vascular cells produce a high level of heat shock proteins (HSP)…
- Trial name
- HSP70 (NCT04743128)
- Testing
- Exercise
- Where
- Mexico
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad Popular Autónoma del Estado de Puebla
Peripheral Arterial Diseases
Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone
The goal of this clinical trial is to learn if the Auryon Atherectomy System with balloon angioplasty safe and effective in treating lower limb blockages.
- Trial name
- AMBITION BTK (NCT06777901)
- Testing
- Auryon Atherectomy System, Balloon Angioplasty
- Where
- 9 sites in United States
- Volunteers
- 224 people
- Sponsor
- Angiodynamics, Inc.
Peripheral Vascular Diseases
A Non-Randomized Study of the NightHawk Peripheral Plaque Excision System During Plaque Excision of Peripheral Arterial Disease
To assess the proximity of the catheter to the vessel wall and to correlate excised tissue with images collected by the integrated Optical coherence Tomography (OCT) imaging system.
- Trial name
- NightHawk (NCT00516308)
- Testing
- NightHawk
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- FoxHollow Technologies
Peripheral Pulmonary Stenosis, In-stent Stenosis
Systemic Rapamycin (Sirolimus) to Prevent In-Stent Restenosis Following Pulmonary Artery Stent Placement
This is a research study to assess whether an oral medication can benefit some patients being treated for peripheral pulmonary stenosis (PPS), which is narrowing of the blood vessels that send blood to the lungs (pulmonary…
- Trial name
- NCT02365415
- Testing
- Sirolimus
- Where
- United States
- Sponsor
- Boston Children's Hospital
Peripheral Artery Disease, Coronary Disease
Evaluation of Patients With Known or Suspected Heart Disease
In this study researchers will admit and evaluate patients with known or suspected heart disease referred to the Cardiology Branch of the National Heart, Lung, and Blood Institute (NHLBI).
- Conditions
- Peripheral Artery Disease, Coronary Disease, Diabetes and Heart Failure, Dilated Cardiomyopathy
- Trial name
- NCT00001313
- Where
- 2 sites in United States
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)