Clinical trials: Peripheral Circulation
Pulmonary Hypertension of the Newborn (PPHN)
Circulatory Changes During Venovenous (VV)- and Venoarterial (VA) Extracorporeal Membrane Oxygenation (ECMO)
Rationale: Persistent pulmonary hypertension of the newborn (PPHN) is a life threatening disease with a high mortality rate. Extracorporeal Membrane Oxygenation (ECMO) with veno-arterial (V-A) or veno-venous (V-V) cannulation can…
- Trial name
- ECMO (NCT00622492)
- Testing
- echocardiography Doppler sonography, blood and urine sampling
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Cardiovascular Disease
Evaluation of Patients With Heart Disease Not Eligible for Research Protocols
An important mission of the National Institutes of Health (NIH) is to develop and carry out research studies designed to improve understanding of disease processes and treatments.
- Trial name
- NCT00001458
- Where
- United States
- Volunteers
- 7,829 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Raynaud's Disease
Safety and Efficacy of Pletal (Cilostazol) for the Treatment of Juvenile Primary and Secondary Raynaud's Phenomenon
Juvenile secondary Raynaud's (ray-knows) Phenomenon is a disorder of the blood vessels in the fingers and sometimes can affect the toes, nose, or ears.
- Trial name
- NCT00048776
- Testing
- Pletal
- Where
- 19 sites in United States
- Volunteers
- 75 people
- Sponsor
- Otsuka America Pharmaceutical
Peripheral Arterial Disease
Acute Effects of Leg Heating on Skeletal Muscle Blood Flow
The purpose of this study is to apply local heat to the legs, thighs and buttocks of patients with peripheral arterial disease and use PET/CT imaging with an injectable stable radiotracer to study direct measurement of blood flow…
- Trial name
- NCT03763357
- Testing
- Heat Therapy (HT)
- Sponsor
- Indiana University
Raynaud's Disease
Safety and Efficacy of Pletal(Cilostazol) for the Treatment of Juvenile Primary and Secondary Raynaud's Phenomenon
Juvenile primary Raynaud's (ray-knows) Phenomenon is a disorder of the blood vessels in the fingers and sometimes can affect the toes, nose, or ears.
- Trial name
- NCT00048763
- Testing
- Pletal
- Where
- 18 sites in United States
- Volunteers
- 75 people
- Sponsor
- Otsuka America Pharmaceutical
Pediatrics, Anesthesia, Local
Validation of Peripheral Perfusion Index in Predicting Successful Supraclavicular Brachial Plexus Block in Pediatrics
Few data are available for the PI as a tool for evaluation of peripheral block success in pediatric patients. Furthermore, there is currently no cut-off value defined for the accuracy of the PI in the detection of successful…
- Trial name
- NCT05815563
- Where
- Egypt
- Volunteers
- 59 people
- Sponsor
- Cairo University
Peripheral Perfusion Index, Caudal Block
Peripheral Perfusion Index as an Early Predictor of Successful Caudal Block in Pediatric Patients Undergoing Lower Abdominopelvic Surgeries Under General Anesthesia
The aim of this study is to assess early predictability of peripheral perfusion index to success of caudal block in pediatric patients undergoing lower abdominopelvic surgeries
- Trial name
- NCT06846983
- Testing
- Peripheral perfusion index pulse oximeter
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Transcatheter Aortic Valve Replacement, Mechanical Circulatory Support
Application of Emergent Peripheral Mechanical Circulatory Support in Transcatheter Aortic Valve Replacement for 6 Patients
Objective: To explore the experience of transcranial aortic valve replacement (TAVR) under emergency mechanical assisted circulation (MCS).Methods: A total of 6 patients who completed TAVR with the assistance of emergency MCS in…
- Trial name
- NCT04464356
- Testing
- mechanical circulatory support
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cerebral Oxygenation, Cerebral Blood Flow
Cerebral Near Infrared Spectroscopy During Blood Sampling From a Peripheral Artery Catheter in Preterm Infants
Preterm infants often need peripheral artery catheters for invasive blood pressure recording and to facilitate blood sampling. Near infrared spectroscopy is a method to evaluate cerebral oxygenation and as well as cerebral blood…
- Conditions
- Cerebral Oxygenation, Cerebral Blood Flow, Prematurity
- Trial name
- NCT00926770
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Cologne
Perfusion Index
Peripheral Perfusion Index as a Predictor of Successful Supraclavicular Brachial Plexus Block
Aim of the study is to determine the best cut off value for the PI and PI ratio for predication of successful supraclavicular brachial plexus block in young and middle age patients undergoing hand surgeries .
- Trial name
- NCT06493643
- Testing
- Measurement of perfusion index after supraclavicular brachial plexus block at blocked & unblocked limb
- Volunteers
- 43 people
- Sponsor
- Ain Shams University
Postoperative Pain, Caudal Anesthesia
Effect of Intravenous Versus Caudal Dexmedetomidine on Perfusion Index and Hemodynamic Responses in Children Undergoing Infraumbilical Surgery
Caudal anesthesia is widely used to provide pain relief for children undergoing surgery below the navel (infraumbilical surgery).
- Conditions
- Postoperative Pain, Caudal Anesthesia, Peripheral Perfusion, Pediatric Surgery
- Trial name
- NCT07852039
- Testing
- Caudal Dexmedetomidine, Intravenous Dexmedetomidine
- Volunteers
- 100 people
- Sponsor
- Assiut University
Poor Peripheral Perfusion
Perfusion Index Variability in Respiratory Distress Syndrome
Perfusion index may vary according to type of surfactant during the treatment of respiratory distress syndrome.
- Trial name
- NCT01852461
- Testing
- Beractant, Poractant alfa
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Dr. Sami Ulus Children's Hospital
Newborn, Infection
Comparison of Peripheral Perfusion Level Between Two Groups of Newborns According to Their Infectious Status Defined by the Criteria of the Center for Disease Control and Prevention (CDC)
Despite advances in medicine, secondary neonatal infection remains a continuing concern because of the associated high morbidity and mortality.
- Trial name
- NCT03117907
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Thrombus in the Central and Peripheral Circulatory System, Including Saphenous Vein Grafts
Prospective Multicenter Study to Characterize the REAL-WORLD EVIDENCE Regarding Safety and Performance of the Aspiration Catheters Family
The purpose of this post market study is to collect clinical data of the Arthesys Aspiration catheters family during percutaneous intervention and/or stenting procedure of vessels in the central and peripheral circulation system…
- Trial name
- NCT05536167
- Where
- France
- Volunteers
- 57 people
- Sponsor
- Arthesys
Perfusion Index
The Role of Perfusion Index in Children
The purpose of our study is to test the usability of the perfusion index in evaluating the success of the peripheral nerve block applied under sedation in children.
- Trial name
- NCT04245735
- Testing
- perfusion index
- Volunteers
- 60 people
- Sponsor
- Erzincan University
Atherosclerosis, Heart Failure, Congestive
The Role of Angiotensin Type I Receptor in the Regulation of Human Peripheral Vascular Function
The renin angiotensin system (RAS) plays an important physiological and pathophysiological role in the control of blood pressure and plasma volume.
- Conditions
- Atherosclerosis, Heart Failure, Congestive, Hypertension, Myocardial Infarction
- Trial name
- NCT00001628
- Testing
- Angiotensin II type 1 receptor antagonists
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Congenital Heart Disease
NIRS Predict Low Cardiac Output State in Neonates and Infants in Cardiac Surgery
Neonates and infants that have cardiac surgery with cardiopulmonary bypass (CPB) for congenital heart disease are at great risk for experiencing life-threatening low cardiac output syndrome (LCOS) in the first 24 hours after…
- Trial name
- NCT01849120
- Testing
- EQUANOX Advance 8004CB sensor
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Mayo Clinic
Drop Foot
The Investigators Are Comparing Lidocaine and Papaverine Nerve Blocks to Determine Which Improves Blood Flow Better, Making the "Phoenix Sign" Clearer on Imaging. This Helps Accurately Diagnose Nerve Compression, Improving Patient Care
This pilot study aims to investigate the effects of nerve blocks in patients with diabetic peripheral neuropathy through a double-blinded, randomized trial involving 4 patients.
- Trial name
- NCT06919289
- Testing
- Infiltration of papaverine, Lidocaine infiltration
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- US Neuropathy Centers
Cardiac Rhythm Disorders, Urological Disorders
Product Surveillance Registry
The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products.
- Conditions
- Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders
- Trial name
- PSR (NCT01524276)
- Where
- 402 sites in United States, Argentina and 39 more
- Volunteers
- 100,000 people
- Sponsor
- Medtronic
Monitoring, Physiological
Perfusion Index in Anesthesia
In patients under general anesthesia the investigators wish to investigate association and covariance between a peripheral perfusion index as obtained by Radical 7 monitor (Masimo, Irvine, CA, USA) and more traditional…
- Trial name
- NCT02989441
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Jakob Højlund