Clinical trials: Peritonitis
Spontaneous Bacterial Peritonitis, Liver Cirrhosis
Role of Probiotics in the Prevention of Spontaneous Bacterial Peritonitis in Cirrhotic Patients: A Randomized Placebo Control Trial
Cirrhotic patients are predisposed to bacterial infection. A large proportion of which is spontaneous bacterial peritonitis(SBP), which are mainly caused by enteric bacteria.SBP in a cirrhotic patients is associated with a high…
- Trial name
- NCT00678613
- Testing
- Probiotics and Norfloxacin
- Where
- India
- Volunteers
- 250 people
- Sponsor
- All India Institute of Medical Sciences
Perforated Diverticulitis
Characteristics of Abdominal Fluid in Patients With Diverticulitis Hinchey III or IV
Perforated diverticulitis of the colon can be complicated by peritonitis, either purulent or fecal. Both are life threatening conditions requiring emergency surgery.
- Trial name
- NCT04427891
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Sahlgrenska University Hospital
Postoperative Pain
Effects of Perioperative Administration of Intravenous Lidocaine in Children Operated on for Acute Generalized Peritonitis
Intravenous administration of lidocaine perioperatively after laparotomy for peritonitis could be an interesting alternative by reducing the duration of postoperative ileus, the intensity of pain and the patient's hospital stay…
- Trial name
- NCT06051630
- Testing
- Lidocaine intravenous, Serum saline intravenous
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Université NAZI BONI
Peritonitis, Appendicitis
Peritoneal Diffusion and Efficacy of Antibiotic Therapy in Pediatric Peritonitis
This is a pilote monocentric prospective study about pediatric peritonitis and antibiotics pharmacokinetic and pharmacodynamic. The investigators will include 41 patients between 3 and 17 years-old during 2 years in the…
- Conditions
- Peritonitis, Appendicitis, Children, Only, Antibiotic Toxicity
- Trial name
- DIFFUPERPED (NCT05308849)
- Testing
- Dosage of serum and peritoneal of the betalactam used for antibiotic treatment
- Volunteers
- 41 people
- Sponsor
- Central Hospital, Nancy, France
End Stage Liver Disease, Infection
A Study on Diagnosis and Treatment of End Stage Liver Disease Complicated With Infection (SESLDIP Study)
Spontaneous bacterial peritonitis (SBP) is a common complication of end-stage liver disease due to various causes. The initial anti-infective medication is appropriate and the patient's survival rate is closely related.
- Conditions
- End Stage Liver Disease, Infection, Spontaneous Bacterial Peritonitis
- Trial name
- NCT03362632
- Testing
- Antibiotics
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Tongji Hospital
Pneumonia, Lung Abscess
Special Use-Result Surveillance of Unasyn-S (Kit) for Intravenous Use - A Surveillance on High-dose (>6 g Daily) Administration -
The purpose of the survey is to study the followings under practical use, regarding the safety and effectiveness in high-dose administration (exceeding 6 g per day) of UNASYN-S and UNASYN-S KIT for intravenous use (UNASYN). 1.
- Conditions
- Pneumonia, Lung Abscess, Peritonitis
- Trial name
- NCT01793688
- Testing
- Sulbactam Sodium/Ampicillin Sodium
- Volunteers
- 982 people
- Sponsor
- Pfizer
SBP, Liver Cirrhosis
Comparison of Efficacy of Cefotaxime, Ceftriaxone, and Ciprofloxacin for the Treatment of SBP in Patients With LC
Spontaneous bacterial peritonitis (SBP) is one of the most serious complications of liver cirrhosis. Mainstay of treatment for SBP is use of proper antibiotics.
- Trial name
- NCT01265173
- Testing
- Cefotaxime, Ceftriaxone, Ciprofloxacin
- Where
- 2 sites in South Korea
- Volunteers
- 261 people
- Sponsor
- Korea University
Peritonitis; Acute, Acute Appendicitis
Retrospective Comparison Between AirSeal® and Standard Insufflation in Appendicular Peritonitis
The AirSeal System Valve-less Trocar is known to decrease postoperative pain, consumption of analgesics, operating time, and length of stay in adults during robotic and laparoscopic procedures.
- Conditions
- Peritonitis; Acute, Acute Appendicitis, Postoperative Pain, Laparoscopy
- Trial name
- APPAS (NCT06734494)
- Testing
- Laparoscopic appendectomy Laparoscopic appendectomy with Airseal or with standard insufflation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Destinval Christelle
Appendicolith, Appendicitis
Laparoscopic Appendectomy Performed by Junior SUrgeonS: Impact of 3D Visualization on Surgical Outcome
Laparoscopy has revolutionized the approach to a number of surgical problems causing a re-evaluation of several clinical strategies.
- Conditions
- Appendicolith, Appendicitis, Appendicitis With Perforation, Appendicitis Peritonitis
- Trial name
- LAPSUS (NCT03770897)
- Testing
- 3D Laparoscopic Appendectomy, 2D Laparoscopic Appendectomy
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Peritonitis
Pedicled Seromuscular Flap For Enforcement Of High Risk Intestinal Anastomoses
This is a control matched prospective study evaluating the use of seromuscular flap for high risk anastomoses.
- Trial name
- NCT01391169
- Testing
- seromuscular flap enforcement
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Abscess, Intra-Abdominal, Abdominal Abscess
A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections
The purpose of the study is to evaluate the safety and tolerability of doripenem compared with meropenem in children hospitalized with complicated intra-abdominal infections.
- Conditions
- Abscess, Intra-Abdominal, Abdominal Abscess, Abdomen, Acute, Abdominal Pain
- Trial name
- NCT01110382
- Testing
- Doripenem, Meropenem, Amoxicillin/clavulanate potassium
- Where
- 19 sites in United States, Argentina and 6 more
- Volunteers
- 41 people
- Sponsor
- Janssen Research & Development, LLC
Peritoneal Dialysis-associated Peritonitis
Improved Diagnosis of Peritoneal Dialysis Peritonitis by Calorimetry
The purpose of this study is to analyze whether calorimetry compared to conventional methods (i.e.blood culture systems)is superior to diagnose peritoneal dialysis related peritonitis.
- Trial name
- NCT00801775
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- University Hospital, Basel, Switzerland
Peritonitis
Change Trend of Effluent Eosinophil During Peritoneal Dialysis-Related Peritonitis
A multi-center prospective cohort study will be conducted to explore the change trend of eosinophil in peritoneal dialysis effluent during peritoneal dialysis-associated peritonitis, and to explore the relationship between…
- Trial name
- NCT04594421
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital
Ascites, Peritoneal Carcinomatosis
Comparison of "Roll-over' Technique With Standard Abdominal Paracentesis in Suspected Peritoneal Carcinomatosis
The study will be a randomized trial that will compare two techniques of abdominal paracentesis in patients with suspected peritoneal carcinomatosis.
- Conditions
- Ascites, Peritoneal Carcinomatosis, Peritoneum Neoplasm, Tuberculous Peritonitis
- Trial name
- ROLLON (NCT04232384)
- Testing
- Standard Paracentesis, Roll Over Paracentesis
- Where
- India
- Volunteers
- 71 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Peritonitis
SIS Multicenter Study of Duration of Antibiotics for Intraabdominal Infection
The major hypothesis to be tested is that the treatment of intraabdominal infections that have been adequately treated operatively or by percutaneous techniques with three to five days of antibiotics will result in outcomes…
- Trial name
- NCT00657566
- Testing
- duration of antibiotics
- Where
- 23 sites in United States, Canada
- Volunteers
- 518 people
- Sponsor
- University of Virginia
Septic Peritonitis
Effects of Dexmedetomidine vs Propofol in Patients With Intra-abdominal Sepsis
Sepsis is defined as systemic response to infection ,and it is a main problem in ICU and despite advance in supportive care, the mortality rate in patients with severe sepsis continues to exceed 30% [Bone RC 1993].The effects of…
- Trial name
- NCT04718714
- Testing
- Midazolam, Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Perforated Diverticulitis
The Damage Control Strategy for the Treatment of Perforated Diverticulitis of the Sigmoid Colon With Diffuse Peritonitis
The best approach for the treatment of perforated diverticulitis of the sigmoid colon is still under debate. Concurrent techniques are 1) resection with primary colorectal anastomosis with or without additional loop ileostomy; 2)…
- Trial name
- NCT04220840
- Testing
- Damage control strategy
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Städtisches Klinikum München GmbH
Peritonitis
Post Surgically Treated Peritonitis Complications
The purpose of this observational study is to investigate the management and the complications associated wtih surgically treated peritonitis.
- Trial name
- NCT03284476
- Testing
- Collection of medical data from ICU patients
- Where
- 5 sites in France
- Sponsor
- Nantes University Hospital
Primary Bacterial Peritonitis
Identification of Ascitic Fluid Bacterial Pathogens in Spontaneous Bacterial Peritonitis
Several studies have pointed out changes in the epidemiology of the causative bacteria in SBP and bacterascites and in their susceptibility to antibiotics.
- Trial name
- NCT02463721
- Testing
- ascitic fluid culture and microbiological testing
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University