Clinical trials: Personality Disorders
Adolescent Psychiatry, Antisocial Personality Disorders
Impaired Decision-making in Adolescents
There is clear evidence that aggressive behavior and disruptive behavior disorders (DBD) in middle childhood are associated with an increased risk for substance abuse in adolescence.
- Conditions
- Adolescent Psychiatry, Antisocial Personality Disorders, Substance-Related Disorders
- Trial name
- NCT01253993
- Where
- Netherlands
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Psychotic Disorders, Psychosis
Semantic and Syntactic Computerized Analysis of Free Speech
Subtle speech disorganization could be predictive of a transition to schizophrenia of ultra-high-risk patients. The aim of our longitudinal multicenter cohort study is to identify specific linguistic markers of the psychotic…
- Conditions
- Psychotic Disorders, Psychosis, Schizophrenia and Related Disorders, Schizophrenia Prodromal
- Trial name
- ASESID (NCT03525054)
- Where
- 3 sites in France
- Volunteers
- 215 people
- Sponsor
- University Hospital, Brest
Malocclusion
Effect of Personality Traits on Reporting Outcomes of Orthodontic Treatment
The study will monitor changes induced by orthodontic treatment and in the retention period, two years after the end of orthodontic treatment. The alignment of teeth, hygiene and gingiva will be assessed.
- Trial name
- OrthoPers (NCT05398328)
- Testing
- active metal appliance, active esthetic appliance, retention fixed appliance
- Where
- Croatia
- Volunteers
- 120 people
- Sponsor
- University of Rijeka
Treatment 1:Dialectical Behavior Therapy (DBT), Treatment as Usual
Efficacy of "DBT-LIVE", an Identity Skills Training Program, for Borderline Personality Disorder.
The main objective of this project is to adapt and evaluate the LIVE Skill module in the Spanish population. LIVE Skill is a psychological intervention protocol specifically designed to address identity disturbances in…
- Trial name
- NCT07684872
- Testing
- DBT LIVE, TAU
- Where
- Spain
- Volunteers
- 112 people
- Sponsor
- Universidad Europea de Valencia
Mood Disorders
Gonadal Steroid Manipulation and Personality Characteristics: Association With Mood Fluctuations and in Vitro Fertilization (IVF) Outcomes
The current study's primary aim is to investigate the association between neuroendocrine fluctuations and mood disorders by monitoring mood states over distinct hormonal phases during in-vitro-fertilization (IVF) treatment.
- Trial name
- IVF (NCT01032421)
- Testing
- IVF procedure
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Conduct Disorder, Psychopathic Personality Trait
CFT-focused Mental Health Intervention With Exposure Training for Youngsters
The aim of this study is to explore if individual CFT-based intervention with exposure training in virtual reality decreases conduct disorder symptoms and callous-unemoitonal traits , as well as increases subjective emotional…
- Trial name
- CFT+VR (NCT05802758)
- Testing
- Psychopathy.comp and training in virtual reality (VR)
- Where
- 2 sites in Finland
- Volunteers
- 144 people
- Sponsor
- Helsinki University Central Hospital
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Homeless Youth Study - Stepping Stone 2.0
Housing instability is both a cause and consequence of mental health problems. As such youth experiencing housing instability (e.g., homeless or marginally housed) have higher rates of mental health problems.Because of their…
- Trial name
- NCT03776422
- Testing
- Mobile self-help intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Personality Disorders, Social Withdrawal of Childhood or Adolescence
Child and Adolescent Psychiatric Personality Structure
The study plan outlined here represents an investigation of instruments on the patients treated in the acute ward of child and adolescent psychiatry at the University Medical Center Hamburg Eppendorf (UKE).
- Conditions
- Personality Disorders, Social Withdrawal of Childhood or Adolescence, Psychosocial Impairment
- Trial name
- CAPPS (NCT05162287)
- Where
- Germany
- Volunteers
- 62 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Prodromal Schizophrenia
Evaluation of Step-Based Care for Individuals at Clinical High Risk for Psychosis
The Ohio State University Early Psychosis Intervention Center is implementing a specialized clinical program to serve individuals who meet clinical high risk criteria for a psychosis.
- Trial name
- NCT03970005
- Testing
- Step-Based Care Model
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Psychotic Disorders, Personality Disorders
The Staged Treatment in Early Psychosis Study
A sequential multistage randomised clinical trial (SMART) to produce evidence to guide a step-wise clinical approach for the treatment of ultra high risk patients and reduction of risk for psychosis and other deleterious clinical…
- Conditions
- Psychotic Disorders, Personality Disorders, Clinical High Risk
- Trial name
- STEP (NCT02751632)
- Testing
- Support and Problem Solving Therapy, Cognitive Behavioural Case Management, Fluoxetine
- Where
- 5 sites in Australia
- Volunteers
- 342 people
- Sponsor
- Orygen
Affective Disorders, Anxiety Disorders
Routine Outcome Monitoring in Mental Health Outpatient
Scientific Background: Inherent gaps exist between the worlds of research and clinical therapy, especially in mental-health systems.
- Conditions
- Affective Disorders, Anxiety Disorders, Psychotic Disorders, Personality Disorders
- Trial name
- ROM-Shalvata (NCT02095457)
- Testing
- Frequent monitoring and feedback
- Where
- Israel
- Volunteers
- 900 people
- Sponsor
- Shalvata Mental Health Center
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Antisocial Behavior
Omega-3 Supplements to Reduce Antisocial Behaviour in Young Offenders
The study aims to examine the effects of providing omega-3 supplements on young offenders' antisocial behaviour. Participants will be randomized into three groups: (1) Omega-3, (2) Placebo and (3) Treatment as Usual.
- Trial name
- NCT03627312
- Testing
- Omega-3, Treatment as Usual
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Singapore Prison Service
Borderline Personality Disorder
Neural Mechanisms of Dialectical Behavioral Therapy in Patients with Borderline Personality Disorder
This research examines the behavioral and neural mechanisms of dialectical behavior therapy (DBT) effect in patients with borderline personality disorder (BPD).
- Trial name
- NeuroDBT (NCT06882330)
- Testing
- Dialectical behavior therapy
- Where
- Czechia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Masarykova Univerzita
Personality Features in Anorexia Nervosa
Motivation to Change, Coping, and Self-Esteem in Adolescent Anorexia Nervosa
By use of several questionaires, this study aimed at an investigation of the changes in motivation, symptoms, self-esteem and coping style in adolescent patients with anorexia nervosa..
- Trial name
- NCT02828956
- Volunteers
- 92 people
- Sponsor
- University of Zurich
Dyssocial Behavior, Antisocial Personality Disorder
Antisocial Behavior: Passing From Parent to Child to Grandchild
Antisocial behavior often occurs in different generations within the same family. However, it is not known what factors contribute to this passing of antisocial behavior from parent to child to grandchild.
- Trial name
- NCT00060788
- Where
- Mauritius
- Volunteers
- 663 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Depression, Trauma
Online Therapy Youth, Equivalent to Treatment As Usual?
With growing waiting lists in specialized youth mental health care (sGGZ) and shortages of care staff, finding creative solutions to respond to this scarcity issue is important.
- Conditions
- Depression, Trauma, Compulsive Disorder, Anxiety
- Trial name
- NCT06617663
- Testing
- EMDR, ACT
- Where
- Netherlands
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- GGZ Noord-Holland-Noord
Borderline Personality Disorder
NEUROIMAGING OF ADOLESCENT BORDERLINE PERSONALITY DISORDER WITH AND WITHOUT POST-TRAUMATIC STRESS DISORDER
Borderline personality disorder (BPD) is a common mental disorder in adolescents with significant individual and societal repercussions, characterized over the long term by emotional hyperresponsiveness, relational instability…
- Trial name
- BorderStress (NCT04852744)
- Testing
- Brain MRI
- Where
- France
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Psychotic Disorders, Prodromal Symptoms
Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy Trial
The present study is a confirmatory efficacy trial of Family Focused Therapy for youth at clinical high risk for psychosis (FFT-CHR).
- Conditions
- Psychotic Disorders, Prodromal Symptoms, Prodromal Schizophrenia, Psychosis
- Trial name
- NCT04338152
- Testing
- Family Focused Therapy for Clinical High Risk Youth (FFT-CHR), Enhanced Care (EC)
- Where
- 7 sites in United States, Canada
- Volunteers
- 220 people
- Sponsor
- University of California, Los Angeles
Aggression, Antisocial Behavior
Omega-3 Supplementation and Behavior Problems
The objectives of this project are as follows: 1. To assess whether omega-3 dietary supplementation for six months can reduce externalizing behavior problems (antisocial and aggressive behavior) in schoolchildren aged 8 to 18…
- Conditions
- Aggression, Antisocial Behavior, Antisocial Personality
- Trial name
- NCT02334098
- Testing
- Omega-3 supplemented drink, Smartfish
- Where
- China
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Dr. Annis Fung