Clinical trials: Pervasive Development Disorders
Schizophrenia, Schizoaffective Disorder
Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study
The purpose of this study is to get a better understanding of the side effect burden and identify predictors of psychotic, mood and aggressive disorders in children and adolescents.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Psychotic Disorder, Not Otherwise Specified
- Trial name
- SATIETY (NCT01269710)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of North Carolina, Chapel Hill
Child, Only
The Effects of SITS in Children With Autism.
The study will include 30 participants whose pre and post values will be calculated. Inclusion criteria for this study is autism spectrum disorder with the age group of 5_11 years ,female and males both are included, those who…
- Trial name
- NCT07428876
- Testing
- sensory integrated therapy exercises
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder
Use of Immersive Virtual Reality to Train the Multisensory Processing Capacities of Children Aged 8 to 16 Years-old With an Autism Spectrum Disorder: Single-center Randomized Pilot Study in Parallel Groups - SEVIRE. (Sensory Virtual Reality)
Autism Spectrum Disorder (ASD) is defined as a neurodevelopmental disorder that affects the functioning and development of social communication (DSM5 - 2013).
- Trial name
- SEVIRE (NCT05171244)
- Testing
- virtual reality training, usual care
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Tours
Autism Spectrum Disorders
Intranasal Oxytocin and Learning in Autism
: The objective of this study is to determine the tolerability and therapeutic potential of oxytocin in children and adolescents with Autism Spectrum Disorders (ASD) when paired with a computer game intervention that is designed…
- Trial name
- NCT02090829
- Testing
- Syntocinon (synthetic oxytocin)
- Where
- United States
- Sponsor
- University of Minnesota
Autism or Autistic Traits, Healthy
Development of Prosocial Behaviors and Related Brain Network in Infants of High and Low Risk of ASD
The goal of this observational study is to compare the developmental trajectories of prosocial behaviors and functional network connections in infants and toddlers at high and low risk of autism spectrum disorder (ASD).
- Trial name
- NCT06329245
- Testing
- Do not take any interventions
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder
Microbiome Determinants of Neurological and Gastrointestinal Symptoms of Autism Spectrum Disorder (ASD)
This observational study aims to identify human microbiome determinants of the symptoms associate with ASD as well as identify the human microbiome determinants of the success of FMT (fecal matter transplant) therapy and to…
- Trial name
- NCT05465148
- Sponsor
- Viome
Genetic Disorder, Asperger Disorder
Pediatric Patients With Metabolic or Other Genetic Disorders
Background: Some patients with unusual genetic conditions are referred to the National Institutes of Health (NIH). They may not be eligible to join current research studies.
- Conditions
- Genetic Disorder, Asperger Disorder, Autism Spectrum Disorder, Fragile X Syndrome
- Trial name
- NCT02769949
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism
Project VOICES: Vocal Optimization in Children Elevating the Spectrum
Thirty percent of children with autism barely talk or do not talk at all despite years of intervention. This study aims to address this important and long-standing challenge by developing a novel intervention to increase the…
- Trial name
- Project VOICES (NCT06875843)
- Testing
- Contingent responses, Contingent responses plus vocal elicitation strategies, Non-contingent control
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt University Medical Center
Autism Spectrum Disorder
Interest of Oxytocin as an Adjuvant Treatment of Psycho-educational Measures in Challenging Behaviors in Children With Autism Spectrum Disorders and Moderate to Severe Intellectual Disability: Feasibility and Safety Study.
The investigation team propose in this study to specifically evaluate the feasibility of using oxytocin in the form of an intranasal spray in a specific population of children with autism spectrum disorder and intellectual…
- Trial name
- OT-DEFI (NCT05864508)
- Testing
- Oxytocin nasal spray
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Autism Spectrum Disorder
Vitamin/Mineral Supplement for Children With Autism
This is an open-label 3 month clinical trial of a vitamin/mineral supplement designed for children with autism.
- Trial name
- NCT04845776
- Testing
- ANRC Essentials Plus
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Autism, Autism Spectrum Disorder
Social Robotics for Autism
Socio-pragmatics focuses on the study of language in the context of social interactions. It explores how individuals use language to communicate effectively in specific social situations, taking into consideration the social…
- Trial name
- SRI (NCT06974240)
- Testing
- Experimental Group, control group
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder
The Impacts of Theta-burst Stimulation on Children and Adolescents With Autism Spectrum Disorder
The investigator would like to investigate the impact of theta-burst stimulation over posterior superior temporal sulcus in children and adolescents with autism spectrum disorder
- Trial name
- NCT03621189
- Testing
- intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Autism Spectrum Disorder
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Open Label
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise…
- Trial name
- NCT05494398
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
Do Sleep and Circadian Rhythm Disturbances Impact the Cognitive and Behavioural Development of Children With Autism?
The primary objective of this study is to undertake a longitudinal investigation of the impact of sleep and circadian rhythm disturbances on cognitive and behavioural trajectories in children with autism spectrum disorder (ASD)…
- Trial name
- NCT02878499
- Testing
- polysomnography
- Where
- 5 sites in France
- Volunteers
- 105 people
- Sponsor
- University Hospital, Strasbourg, France
Autism Spectrum Disorder
The Effect of Simulation-based Training on Confidence and Competence in Obtaining Vitals in a Child With Autism
The objective is to evaluate the efficacy of an online learning module combined with high fidelity simulation-based training in improving medical assistants' and registered nurses' self-confidence and competence scores in taking…
- Trial name
- NCT05288868
- Testing
- Educational Intervention: online didactic lecture and educational simulation activity
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Autistic Disorder
Field Test of Motivity.Net Software for Data Collection During Behavioral Interventions
This is a study funded by a Phase II SBIR to build and test the feasibility of a new software prototype for delivering evidence-based behavioral therapy treatment for autism.
- Trial name
- NCT03919721
- Testing
- Applied Behavioral Analysis
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Experiad LLC
Autism, Autism Spectrum Disorder
Environmental Influence on Mental Illness Via Modifications of Genomes and Metabolomes in Adolescents With Autism
The aim of the study is to enrich the understanding of the physiological mechanisms that predispose autistic adolescents to mental illness.
- Trial name
- ENIGMA-I (NCT06299618)
- Where
- 3 sites in Ireland, Romania and 1 more
- Volunteers
- 400 people
- Sponsor
- University College Cork
Autism, Autism Spectrum Disorder
Cognitive Control and Metacognition Training
95 autistic children (ages 8-11yrs) will be randomly assigned to a novel computer-based Cognitive Control Training combined with Metacognition Coaching or to a comparison group that receives the intervention after a delay.
- Trial name
- CoMeT (NCT06885684)
- Testing
- Cognitive Control Training + Metacognition Coaching
- Volunteers
- 95 people
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorders, Autism
Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Anxiety disorders affect 40 to 50% of children with autism spectrum disorders (ASD), contributing to substantial distress and impairment.
- Conditions
- Autism Spectrum Disorders, Autism, Asperger's Syndrome, Pervasive Developmental Disability - Not Otherwise Specified
- Trial name
- TAASD (NCT02028247)
- Testing
- Personalized Cognitive-behavioral therapy, Standard Practice Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism Spectrum Disorders, ADHD
Novel Measure of Social Deficits in Children
Autism Spectrum Disorders (ASD) feature impairments in social interaction and communication. Drug and behavioral treatments for ASD are undergoing rapid development, yet our diagnostic tools are not suitable for efficacy…
- Trial name
- OATS (NCT02035176)
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
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