Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder, Autism
Pilot Trial of Pregnenolone in Autism
This is a research study to examine the tolerability and effectiveness of pregnenolone in individuals with autism. Pregnenolone is a naturally occurring steroid hormone in the brain that has been implicated in treating various…
- Trial name
- NCT02627508
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
BCI (Brain Computer Interface) Intervention in Autism
This study aims to demonstrate that improvements in identification of social clues (and improvement of overall social behaviour) in subjects with ASD can be achieved using social games together with a BCI setup.
- Trial name
- BCIAUT (NCT02445625)
- Testing
- BCI to train joint attention in ASD
- Volunteers
- 15 people
- Sponsor
- University of Coimbra
Cerebral Palsy, Autism or Other Neuromotor Behavior Abnormalities Correlation With Anthropometry
Is There Any Correlation Among Neonates Anthropometry and Neuromotor Behaviour
To explore the association among anthropometric parameters and neuromotor behaviour in neonates for early identification and prediction of later neuromotor deficit.
- Trial name
- NCT05361213
- Where
- India
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Autism Spectrum Disorder
Parent-mediated Developmental Behavioral Intervention
This study explores the effectiveness of two intervention programs: "Long-distance developmental behavioral intervention" and "developmental behavioral interventions" for children with autism spectrum disorder or multiple…
- Trial name
- PDBI (NCT03812068)
- Testing
- Long-distance developmental behavioral intervention, Developmental behavioral intervention
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong
Autism
Improving Attention Skills of Children With Autism
Toddlers with autism have poor joint attention skills. Joint attention skills include pointing to objects, following another person's gaze, and responding to invitations to join in a social interaction.
- Trial name
- NCT00065910
- Testing
- Caregiver joint attention intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism, Autism Spectrum Disorder
A Behavioral Intervention for Ameliorating Sleep Problems in Children With ASD
The present study will test the effectiveness of a behavioral intervention program that targets sleep problems in 1.5-5-year-old children with ASD.
- Conditions
- Autism, Autism Spectrum Disorder, Sleep
- Trial name
- NCT04539990
- Testing
- Behavioral treatment for sleep difficulties
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Autism Spectrum Disorder (ASD), Autism
Judo Training for People With Autism Spectrum Disorder, Physical Fitness and Psychological Indicators
Physical fitness and psychological indicators are key factors in healthy development. Individuals with autism spectrum disorder (ASD) tend to have lower levels of physical fitness and mental health than their neurotypical peers.
- Trial name
- JUDOASD/PA/PSY (NCT07419919)
- Testing
- Judo training for people with ASD - training in integration groups with non-ASD people
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Autism Spectrum Disorder
A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)
This is a non-drug study seeking to characterize different scales to measure repetitive and restrictive behaviors in different ASD sub-populations over time. This study will also explore the use of digital biomarkers.
- Trial name
- NCT03611075
- Testing
- No Intervention
- Where
- 18 sites in United States, Canada and 1 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Autism Spectrum Disorder, Moderate Language Delay
Direct Instruction Language for Learning in Autism Spectrum Disorder
The purpose of this study is to test whether Direct Instruction - Language for Learning (DI-LL) is an effective way to teach language skills to children with autism spectrum disorder (ASD) and moderate language delay.
- Trial name
- DILLASD (NCT02483910)
- Testing
- Direct Instruction-Language for Learning (DI-LL) via telehealth (e.g., Zoom or WebEx), Standard of care delivered via telehealth (e.g., Zoom or WebEx)
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Emory University
Autism Spectrum Disorder
A Trial of Project ImPACT in Early Intervention
Our pilot study will address a number of pressing questions, including: Can community clinicians successfully coach parents of children with ASD in evidence-based practice to achieve positive outcomes for their children and…
- Trial name
- NCT04729127
- Testing
- Project ImPACT
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Pennsylvania
Neurodevelopmental Disorders, Autism
Early Life Anemia and Children's Risk of Neurodevelopmental Disorders: National and Regional Register-based Studies
The overall project aim is to study children's neurodevelopmental outcomes (including diagnoses of autism, ADHD, and intellectual disability) following exposure to maternal anemia during pregnancy or anemia during the first year…
- Conditions
- Neurodevelopmental Disorders, Autism, ADHD, Intellectual Disability
- Trial name
- NCT06199362
- Where
- Sweden
- Volunteers
- 2,400,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Autism Spectrum Disorder
Folinic Acid in Autism
An examination of changes in urinary metabolites with use of folinic acid in children with autism spectrum disorder (ASD). Investigators will also measure behavioral measures and academic measures monthly at school with teachers…
- Trial name
- NCT03771560
- Testing
- folinic acid
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of California, San Francisco
Autistic Spectrum Disorder
Treatment of Children With Autistic Spectrum Disorder With Autologous Umbilical Cord Blood, a Pilot Study
This study is a phase II, prospective, double blind, placebo-controlled study of the efficacy of autologous umbilical cord blood infusion. The study population will consist of 60 children ages 18 months to 12 years with ASD.
- Trial name
- NCT04243382
- Testing
- Autologous umbilical cord blood
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Autism, Intervention (Training) Condition
Parent-Mediated Social Cognition Intervention for Young Children With Autism Spectrum Disorder
This study evaluates the efficacy of the Companion Mind-Drawing Cooperative Game Program, a parent-mediated, home-based structured play intervention targeting social cognitive development in young children with autism spectrum…
- Conditions
- Autism, Intervention (Training) Condition, Social Cognition, Cognition Improvement
- Trial name
- PMSC-ASD (NCT07708246)
- Testing
- Companion Mind-Drawing Cooperative Game Program
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder
Effect of Aquatic Training on Motor Function in Children With Autism Spectrum Disorder
Clinically, infants with Autism Spectrum Disorder often display gross motor delays in supine, prone, and sitting skills in their first year of life .
- Trial name
- NCT05123066
- Testing
- Aquatic Exercises, Land Exercises
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Autism
SynapDx Autism Gene Expression Analysis Study (STORY)
This study will prospectively enroll approximately 880 children, at least 18 months and less than 60 months of age, who have been referred to a pediatric developmental evaluation center.
- Trial name
- STORY (NCT01810341)
- Where
- 20 sites in United States, Canada
- Volunteers
- 880 people
- Sponsor
- SynapDx
Autism Spectrum Disorders
The Role of Vasopressin in the Social Deficits of Autism
Researchers at the Stanford University School of Medicine are seeking participants for a study examining the effectiveness of vasopressin, a neuropeptide, in treating children with autism spectrum disorder.
- Trial name
- NCT01962870
- Testing
- Vasopressin
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Stanford University
ADHD, Autism Spectrum Disorders
Internet-based Support for Young People With ADHD and Autism - a Controlled Study
Young people between age 15 and 25 with ADHD and/or autism spectrum disorders are offered internet-based support and coaching during eight weeks (chat and e-mail).
- Trial name
- NCT02300597
- Testing
- Internet based support and coaching
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Göteborg University
Autistic Spectrum Disorder, Somatic Disorders
Somatic Diseases in Autistic Children
For many reasons, medical monitoring in autistic patients is very difficult. This study is designed to determine the prevalence of comorbid diseases (neurological, cardiac, digestive, dental diseases…) in patients suffering from…
- Trial name
- SDA (NCT05077020)
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Montpellier
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