Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder, Autism
Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined.
Autism spectrum disorder (ASD) is a neurodevelopmental condition with core deficits in social communication and behavior, often accompanied by gastrointestinal (GI) and metabolic dysfunction.
- Conditions
- Autism Spectrum Disorder, Autism, Autism Spectral Disorder
- Trial name
- GARM-Autism (NCT07546942)
- Testing
- Autologous MSC isolation, concentration, and cryopreservation of adult mesenchymal stem cells, Fecal Biomicrome Transplantation (FMT), Ketogenic RESET Diet Protocol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Black Tie Medical, Inc.
Autism Spectrum Disorder, Autistic Disorder
Sensorimotor Affect Relationship-based Therapy (SMART) for Children With Autism Spectrum Disorders Ages 2-12
The SMART Program at Nationwide Children's Hospital is an interdisciplinary social skills group that teaches children with autism spectrum disorders (ASD) ages 2-12 the fundamental social skills necessary to build and maintain…
- Trial name
- SMART (NCT01977248)
- Testing
- Sensorimotor Affect Relationship-based Therapy (SMART)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Nationwide Children's Hospital
Autism, Language Delay
Music Therapy for Language and Social Skills in Autistic Children
This research is a single-blind randomized controlled trial, where the investigators plan to recruit 40 children with autism, randomly divided into two groups.
- Conditions
- Autism, Language Delay, Speech Disorders in Children
- Trial name
- NCT06110884
- Testing
- music therapy, speech therapy, speech therapy
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Telehealth Intervention for Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is one of the most frequently occurring childhood-onset neurodevelopmental disorders affecting 1 in every 54 children.
- Trial name
- NCT04832152
- Testing
- OT4ASD
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Autism Spectrum Disorder
Effect of Probiotic Compound K11T e K11TMax in ASD
The research is characterized as a randomized, double-blind clinical trial (phase III) in which administered the probiotic K11-T (with and without added amino acids, fatty acids and vitamins) to children between 3 and 11 years…
- Trial name
- ASD (NCT06382909)
- Testing
- Inflammatory level, Cognitive assessment, Pedagogical assessment
- Where
- 2 sites in Brazil
- Volunteers
- 505 people
- Sponsor
- Deivis de Oliveira guimaraes
Anxiety Disorder, Autism Spectrum Disorder
Anxiety Intervention for Preschool Children With ASD
This study evaluates the feasibility, acceptability, and preliminary efficacy of a treatment program for anxiety in preschool children with autism spectrum disorder.
- Trial name
- NCT04432077
- Testing
- DINO Strategies for Anxiety and fear of Uncertainty Reduction (DINOSAUR)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Autism Spectrum Disorder (ASD)
Double-blind Trial of Buspirone for the Treatment of Anxiety in Youth With Autism Spectrum Disorders
The main objective of this exploratory 8 week pilot study is to evaluate the safety and efficacy of buspirone for the treatment of anxiety in youth (ages 6-17 years) with autism spectrum disorders.
- Trial name
- NCT01395953
- Testing
- Buspirone
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Attention-Deficit Hyperactivity Disorder, Unspecified Type, Autism Spectrum Disorder
A Multi-dimensional Prospective Study to Discover Gene-microenvironment Interactions in Neurodevelopmental Disorders
This project is the first involving the two most common neurodevelopmental disorders, ASD and ADHD, as well as TDC to establish a multi-dimensional database (clinic, behavior, neurocognitive function, brain imaging, metabolomics…
- Trial name
- NCT04878575
- Testing
- ASD diagnosis, Psychiatric diagnosis
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- National Taiwan University Hospital
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Evaluation of the Efficacy of Hippotherapy for Children With Developmental Disorders
Hippotherapy is every program of horseback riding meant to treat people with physiological, mental, social, cognitive or behavioral problems.
- Trial name
- NCT00717392
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Autism Spectrum Disorder, Feeding Disorder
The Sequential Oral Sensory Approach for Limited Food Repertoire in Children With Autism Spectrum Disorder
There is a paucity of research evaluating the effectiveness of a multidisciplinary approach in an outpatient clinic setting in the management of feeding problems in children diagnosed with ASD.
- Conditions
- Autism Spectrum Disorder, Feeding Disorder, Restricted Diet
- Trial name
- SOS (NCT02435407)
- Testing
- SOS, Education
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Motor Impairments in Children With Autism Spectrum Disorder: a Multimodal Approach
The general goal of the present proposal, Progetto MOSAICO, is the identification of a multimodal panel of neuropsychological, kinematic, neurophysiological, and genetic markers associated with motor abnormalities present in ASD.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Intellectual Disability
- Trial name
- MOSAICO (NCT04769011)
- Testing
- Clinical evaluation, Neuropsychological evaluation, Neurophysiological evaluation
- Where
- Italy
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Autism Spectrum Disorder, Autism in Children
Abdominal Transcutaneous Electrical Acupoint Stimulation on Children With Autism Spectrum Disorder
The goal of this clinical trial is to learn if abdominal transcutaneous electrical acupoint stimulation (abdominal TEAS) works to treat autism spectrum disorder (ASD) in children.
- Trial name
- TEAS/ASD (NCT06763237)
- Testing
- abdominal transcutaneous electrical acupoint stimulation (abdominal TEAS)
- Where
- 2 sites in China
- Volunteers
- 42 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Autistic Disorder
A Longitudinal Study on the Safety and Efficacy for Subjects With ASD Who Received MeRT
The purpose of this study is to continue to evaluate the long-term effectiveness of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) in children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02746445
- Testing
- No intervention
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Wave Neuroscience
Autism Spectrum Disorder
Promoting Transactional Supports to Optimize Social Communication Outcomes for Infants and Their Families
This early treatment project is designed to address two significant public health challenges - the need for validated, manualized, treatments for young children with Autism Spectrum Disorder (ASD) that are cost-efficient and…
- Trial name
- NCT03307057
- Testing
- Social Communication Growth Charts (SCGC), Parent-Implemented (P-I) Condition, Clinician-Implemented (C-I) Condition
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- Emory University
Autism, Autism Spectrum Disorder
Comparing Imitation and Stereotyped Behaviors in Autistic Children: Robots vs. Human Operators
Virtual QT is a social robot designed to interact with humans in social and educational contexts. Equipped with visual and vocal interfaces, the robot can recognize and respond to various human inputs, providing emotional support…
- Trial name
- NCT06144528
- Testing
- QT robot
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Self-Injurious Behavior, Autism Spectrum Disorder
Deep Brain Stimulation for Severe Self-Injurious Behaviour in Children
Deep Brain Stimulation for the Treatment of Severe Refractory Self-Injurious Behaviour in Children with Autism Spectrum Disorder: A Randomized Trial To evaluate the effectiveness of deep brain stimulation (DBS) of the nucleus…
- Trial name
- NCT06529380
- Testing
- DBS ON, DBS OFF
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- The Hospital for Sick Children
Autism
Investigation of Neuroserpin as an Autism Candidate Gene
Previously it has been shown that Familial Encephalopathy with neuroserpin inclusion bodies (FENIB) patients develop abnormalities that partially overlap with Autism Spectrum disorders (ASD), confounded with additional features…
- Trial name
- NCT00917683
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Autistic Disorder
Associative Memory in Autism Spectrum Disorder
The aim of this study is to investigate the neural substrates of associative memory in Autism Spectrum Disorder using both behavioural and EEG assessments.
- Trial name
- MEM-TA (NCT02265094)
- Testing
- Electroencephalography, Neuropsychological assessment
- Where
- France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Autism Spectrum Disorder
Multisensory Room in Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a complex neurological development with onset in infancy or early childhood. Atypical sensory processing has been widely reported in ASD, and recent literature suggest that this abnormality…
- Trial name
- NCT06184802
- Testing
- TAU+Multisensory room, TAU
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Autism
Prebiotic Intervention for Autism Spectrum Disorders
The purpose of this study is to determine the effect of a prebiotic (BGOS) on gut microbiota and metabolites in children with autism spectrum disorders.
- Trial name
- NCT02720900
- Testing
- B-GOS, Maltodextrin
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Clasado Limited
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