Clinical trials: Phacoemulsification
Macular Holes
Evaluation of Anatomic and Visual Outcomes of Initially Closed Macular Holes
To evaluate the anatomic and visual outcomes in patients with initially closed macular holes after vitreoretinal surgery and with one to seven years of follow-up.
- Trial name
- NCT01229657
- Where
- China
- Volunteers
- 79 people
- Sponsor
- Sun Yat-sen University
Epiretinal Membrane
Phacoemulsification and 25 Gauge (25G) Vitrectomy Versus Phacoemulsification Only in Idiopathic Epiretinal Membranes
The purpose of the study is to evaluate the difference in Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity, oct retinal thickness and microperimetry in 2 groups of 30 eyes each affected by idiopathic epiretinal…
- Trial name
- NCT01771939
- Testing
- 25-G vitrectomy and phacoemulsification, phacoemulsification (cataract surgery)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
High Myopia, Low Intraocular Pressure
Improved Operation of Low Intraocular Pressure in Phacoemulsification for Patients With High Myopia Complicated With Cataract
Approximately 60 participants at Eye Hospital of Wenzhou Medical University during October,2021 to January 2022 will be enroll in the investigators' study.
- Trial name
- NCT05201677
- Testing
- Supplement of perfusion fluid through the subiris suspensory ligament space from the lateral incision
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yune Zhao
Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up)
Subincisional Pockets for Sealing Clear Corneal Incisions in Cataract Surgery
The main goal of the sub-incisional pocket (SIP) is to provide a wound seal option during corneal surgery. This retrospective cohort study aims to report the efficacy and safety of SIP among eyes undergoing routine cornea surgery…
- Conditions
- Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up), Phacoemulsification Cataract Surgery, Wound Closure Technique
- Trial name
- SIPSIP (NCT07821203)
- Testing
- Sub-Incisional Pocket
- Where
- Philippines
- Volunteers
- 35 people
- Sponsor
- Philippine Eye Research Institute
Cataract
Anterior Capsule Polishing Effect on Effective Lens Position
The purpose of this study is to evaluate effects of anterior capsule polishing on effective lens position (ELP) and actual axial movement of the intraocular lens (IOL) by measuring anterior chamber depth (ACD) patients with…
- Trial name
- NCT01598428
- Testing
- anterior capsule polishing
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shandong University
Cataract
Registry of PHAcoemulsification for Cataract Surgery
Cataracts cause vision loss due to opacities in the lens. Cataract surgery is performed by emulsifying the nucleus of the lens. A phacoemulsifier is the machine used to deliver ultrasonic energy in the eye to fragment the lens…
- Trial name
- ROPHACS (NCT06659419)
- Where
- France
- Volunteers
- 100,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Corneal Endothelial Cell Loss, Pseudoexfoliation Syndrome
Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome
To study corneal endothelial cells changes after phacoemulsification in patients with senile cataract and pseudoexfoliation syndrome (PEX) compared with control patients with senile cataract using specular microscope.
- Trial name
- NCT05447130
- Testing
- phacoemulsification
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Cataract
Laser Treatment of the Crystalline Lens
The use of a femtosecond laser in cataract surgery that gives equivalent or improved results comapred to conventional phaco-emulsification surgery.
- Trial name
- NCT01001117
- Testing
- LensAR laser surgery, Phaco-emulsification cataract surgery
- Where
- Mexico
- Volunteers
- 75 people
- Sponsor
- LensAR Incorporated
Diabetes, Cataract
Healing of Corneal Incision After Cataract Surgery in Diabetic Patients
The objective of this observational study was to understand the healing of corneal incision after cataract surgery in diabetic patients and its influencing factors.
- Trial name
- NCT07076420
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Zhongnan Hospital
Non-Proliferative Diabetic Retinopathy
Intravitreal and Intracameral DEX in NPDR
To investigate the effects of intravitreal and intracameral injection of dexamethasone during cataract phacoemulsification in patients with mild to moderate non-proliferative diabetic retinopathy
- Trial name
- NCT06951087
- Testing
- Dexamethasone sodium phosphate
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Affiliated Hospital of Nantong University
Pseudophakic Cystoid Macular Lesions After Uncomplicated Standard Phacoemulsification
Pseudophakic Cystoid Macular Lesions After Uncomplicated Standard Phacoemulsification
To assess the incidence, risk factors and clinical courses of cystic macular lesions (CMLs) after uncomplicated phacoemulsification and evaluate the efficacy of topical NSAIDs on the prevention of pseudophakic cystic macular…
- Trial name
- NCT03106402
- Testing
- topical bromfenac sodium hydrate
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Cataract With Exfoliation Syndrome
Efficacy of a Capsular Tension Ring in Preventing Anterior Capsule Shrinkage After Cataract Surgery in Exfoliation Syndrome
The purpose of this study is to examine the efficacy of a capsular tension ring (CTR) in preventing anterior capsule shrinkage after cataract surgery in exfoliation syndrome (XFS) with no zonular weakness.
- Trial name
- Effect of CTR (NCT01455168)
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- University of Occupational and Environmental Health
Dislocated Lens, Pars Plana Vitrectomy
Effectiveness and Safety of 25-Gauge Needle-Assisted Phacoemulsification of Dislocated Intravitreal Lens Nucleus
The goal of this observational study is to learn about the effects of 25-gauge (G) needle-assisted phacoemulsification to remove dislocated intravitreal lens nuclei.
- Conditions
- Dislocated Lens, Pars Plana Vitrectomy, Phacoemulsification, Needle
- Trial name
- NCT06709378
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Changzhou No.2 People's Hospital
Ultrasound Biomicroscopy, Intraocular Lens
Ultrasound Biomicroscopic Assessment of Intraocular Lens Tilt and Decenteration After Phacoemulsification
This study aims to assess intraocular lens (IOL) tilt and decenteration by means of ultrasound biomicroscopy after phacoemulsification.
- Conditions
- Ultrasound Biomicroscopy, Intraocular Lens, Tilt, Decenteration
- Trial name
- NCT07769944
- Testing
- Ultrasound biomicroscopy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Glaucoma, Cataracts
Intraocular Pressure Control Following One Site Versus Two Site Combined Phacoemulsification/IOL And Trabeculectomy
The purpose of this study is to compare the safety \& effectiveness of the two types of cataract and glaucoma surgeries. Results from this study may improve the surgical and post surgical management and long term management of…
- Trial name
- NCT00695747
- Testing
- 2 Site procedure- Phacoemulsification/IOL and Trabeculectomy
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Lahey Clinic
Narrow-Angle Glaucoma
Combined VCST With Phacoemulsification Versus Phacoemulsification in Primary Angle Closure Glaucoma
As ab externo metal probe trabeculotomy cannot achieve 360-degree circumferential angle surgery, prolene suture can be used to achieve this without the need for an illuminated microcatheter.
- Trial name
- NCT06120621
- Testing
- Arm 1 : VCST-phaco group , Arm 2 : phaco group.
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Astigmatism
Incisional Correction of Corneal Astigmatism During Phacoemulsification
Today, cataract surgery is regarded as refractive surgery, mainly aiming emmetropia, and this makes eliminating corneal astigmatism is critical.
- Trial name
- NCT04418986
- Testing
- opposite clear corneal incisions (OCCI)
- Where
- Iraq
- Volunteers
- 40 people
- Sponsor
- Al-Rasheed University College
Cataract
Efficacy of Honan Balloon in Intraocular Pressure Reduction Before Phacoemulsification
-Does Honan balloon reduce intraocular pressure preoperatively?
- Trial name
- NCT00386438
- Testing
- Honan balloon application
- Where
- Thailand
- Sponsor
- Chulalongkorn University
Open Angle Glaucoma and Cataract
RCT to Investigate if Prostaglandin Analogue Drops Increase the Risk of Cystoid Macular Oedema After Cataract Surgery.
Post-operative cystoid macular oedema (CMO) is a common complication causing visual loss following routine cataract surgery. This complication is more prevalent in eyes with excessive inflammation as they heal from surgery.
- Trial name
- CMO (NCT03292796)
- Testing
- Prostaglandins
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Julie Dawson
Nuclear Cataract
Phacoemulsification at High IOP and Physiologic IOP: Impact on Anterior and Posterior Segment Physiology
The purpose of this study is to investigate the anterior and posterior structure and functional changes and vascular alterations when performing phacoemulsification at high IOP vs low, more physiological IOP using Centurion®…
- Trial name
- NCT05765201
- Testing
- High IOP, Low IOP
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Matthew Rauen