Clinical trials: Pharmaceutical Preparations
Thyroid Cancer, Differentiated Thyroid Carcinoma
Effect of Lithium Carbonate on Low-Dose Radioiodine Therapy in Early Thyroid Cancer
This study will examine the safety and effectiveness of using lithium, which has been used to enhance the effectiveness of high-dose 131I, with a single low dose (30 mCi) of 131I for thyroid ablation in patients with recently…
- Trial name
- NCT00251316
- Testing
- Lithium Carbonate
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
HIV Infections
Depo-Medroxyprogesterone Acetate (DMPA, Depo-Provera) Use With Certain Anti-HIV Drugs in HIV-Infected Women
The purpose of this study is to look at the level of depo-medroxyprogesterone acetate (DMPA or Depo-Provera) in the blood to see if is affected by certain anti-HIV drugs (nelfinavir [NFV], efavirenz [EFV], indinavir [IDV] in…
- Trial name
- NCT00016601
- Testing
- Indinavir sulfate, Ritonavir, Nelfinavir mesylate
- Where
- 32 sites in United States, Puerto Rico
- Volunteers
- 76 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Postcoital Contraception
Emergency Contraception - User's Profile
Retrospective analysis of requests of emergency hormonal contraception using pharmacy protocols registered in 2003 and 2006.
- Trial name
- NCT01771016
- Volunteers
- 729 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Chronic Diseases
A Cluster-randomized Controlled Knowledge Translation Feasibility Study in Alberta Community Pharmacies
Background: Despite evidence of benefit for pharmacist involvement in chronic disease management, the provision of these services in community pharmacy has been suboptimal.
- Trial name
- NCT02191111
- Testing
- Task-focused facilitation
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Diabetes, Cardiac Disease
Analysis of Changes in Medication Prescriptions After Hospitalization for 4 Disciplines: Gerontology, Diabetology, Cardiology and Rheumatology: Medical, Pharmaceutical and Economic Aspects
The modifications of the medicinal treatments secondary to the hospitalizations have multiple reasons: reassessment of the previous treatment (conciliation), new therapeutic necessities, potential risk of iatrogeny or of drug…
- Conditions
- Diabetes, Cardiac Disease, Rheumatic Diseases
- Trial name
- PHMEV (NCT03371303)
- Testing
- collection of prescription data
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Palatability Assessment of 3D-printed Chewable Tablets in Children and Adolescents
Chewable Tablets Produced by Three-Dimensional Printing: A Sensory Acceptability Study in Children and Adolescents
The lack of appropriate pediatric formulations compromises adherence and the effectiveness of oral treatment in children, mainly due to the splitting of adult tablets and low sensory acceptability.
- Trial name
- ACEITA3D (NCT07424495)
- Volunteers
- 100 people
- Sponsor
- University of Brasilia
Medication and Supplement Use During Pregnancy
Retrospective Analysis of Hospital Medical Records on Medication and Supplement Use in Pregnant Women
Monocentric study in University Hospitals Leuven (campus Gasthuisberg). Hospital medical records from all pregnant women who delivered between 01/07/2015 and 31/12/2015 in University Hospitals will be analyzed for the presence of…
- Trial name
- NCT02842216
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Migraine Headache, Migraine
Assessment of the Impact of Headache on the Employee Population of Libbs Pharmaceutical Ltd
The main objective of this study is to evaluate the impact of primary headaches using data previously collected in a healthcare program conducted by Libbs with its employees.
- Trial name
- NCT07295587
- Where
- Brazil
- Volunteers
- 1,342 people, healthy volunteers welcome
- Sponsor
- Libbs Farmacêutica LTDA
Wound Healing
Rationale for New Topical Anthroponotic Cutaneous Leishmaniasis (ACL) Treatment in Kabul
The aim of the randomized double blind trial with 134 patients presenting old world cutaneous leishmaniasis is: to evaluate the clinical efficacy of electro-thermo-cauterisation (ETC) followed by moist wound treatment versus ETC…
- Trial name
- rtt-ACL (NCT00947362)
- Testing
- Electro-thermo-coagulation, DAC N-055, saline
- Where
- Afghanistan
- Volunteers
- 134 people
- Sponsor
- Waisenmedizin e. V. Promoting Access to Essential Medicine
Dravet Syndrome
Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Participants With Inadequately Controlled Dravet Syndrome
This Phase 3 study will enroll participants diagnosed with Dravet Syndrome (DS) who are still experiencing at least one tonic-clonic, clonic, and/or focal seizures with motor components (FSMC) per week, despite ongoing treatment…
- Trial name
- NCT02318563
- Testing
- Cannabidiol Oral Solution
- Sponsor
- INSYS Therapeutics Inc
Cystic Fibrosis
A Study to Compare US Marketed Creon Manufactured With a Modernized Process at an Alternate Manufacturing Site and Manufactured With the Approved Manufacturing Process at an Alternate Active Pharmaceutical Ingredient Site, in Participants With Exocrine Pancreatic Insufficiency Due to Cystic Fibrosis
Part 1 is a study to demonstrate that Creon (pancrelipase) delayed release (DR) capsules manufactured with a modernized process (MP) is non-inferior to currently marketed pancrelipase DR capsules in participants with exocrine…
- Trial name
- NCT03924947
- Testing
- Pancrelipase
- Where
- 13 sites in United States
- Volunteers
- 36 people
- Sponsor
- AbbVie
Influenza
A Randomized, Controlled, Unblinded, Clinical Trial of the Acceptability and Efficacy of Non-Pharmaceutical Methods in Preventing Spread of Influenza Within the Family
The proposed study will evaluate whether the use of non-pharmaceutical methods, such as surgical masks, isolation of patients and personal hygiene, are acceptable and effective in preventing the spread of influenza within the…
- Trial name
- NCT00410176
- Testing
- sanitation and personal hygiene
- Volunteers
- 400 people
- Sponsor
- Ministry of Health, Israel
Type 2 Diabetes Mellitus
Alogliptin Tablets Specified Drug-use Survey "Type 2 Diabetic Patients Receiving Combination Therapy With a Hypoglycemic Agent (e.g., Insulin Preparations or Rapid-acting Insulin Secretagogues)"
The purpose of this survey is to evaluate the safety and efficacy of long-term use of alogliptin tablets (Nesina Tablets) in type 2 diabetic patients who have had an inadequate response to hypoglycemic agents (e.g., insulin…
- Trial name
- NCT02221284
- Testing
- Alogliptin
- Where
- 2 sites in Japan
- Volunteers
- 964 people
- Sponsor
- Takeda
Infection, Hemodialysis Patients
The Impact of Pharmaceutical Care on the Infection Control Measures Among Hemodialytic Patients
The study aims to assess the effectiveness of pharmaceutical care in reducing infection rates among hemodialysis patients with central venous (CV) lines.
- Trial name
- NCT06968754
- Testing
- Intervention Group
- Where
- Iraq
- Volunteers
- 90 people
- Sponsor
- University of Sulaimani
Refractory Epilepsy
Expanded Use of Cannabidiol Oral Solution
To allow subjects who have completed Insys 030 extension study to continue to take Cannabidiol oral solution.
- Trial name
- NCT03196934
- Testing
- Cannabidiol oral solution
- Sponsor
- MultiCare Health System Research Institute
Seizures
Cannabidiol Oral Solution as an Adjunctive Treatment for Treatment-resistant Seizure Disorder
This is a multicenter, open-label trial to assess the long-term safety and efficacy of Cannabidiol Oral Solution as adjunctive therapy for pediatric participants with treatment-resistant seizure disorders, including…
- Trial name
- NCT02318602
- Testing
- Cannabidiol Oral Solution
- Where
- 11 sites in United States
- Volunteers
- 52 people
- Sponsor
- INSYS Therapeutics Inc
Acne Vulgaris
Study Comparing Clindamycin Phosphate and Benzoyl Peroxide Gel to Acanya® Gel and Both to a Vehicle Control in the Treatment of Acne Vulgaris
The objective of this study is to compare the safety and efficacy profiles of Taro Pharmaceutical Inc.'s Clindamycin Phosphate and Benzoyl Peroxide Gel 1.2%/2.5% to Acanya® (Clindamycin Phosphate and Benzoyl Peroxide) Gel…
- Trial name
- NCT01769235
- Testing
- Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2%/2.5%, Acanya® Gel, 1.2%/2.5%, Vehicle of test product
- Volunteers
- 1,215 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Keloid
A Clinical Study on the Safety and Efficacy of Wide-Band Ultrasound Combined With Traditional Chinese Medicine Preparations in the Prevention and Treatment of Keloids
The prevention and treatment of patients with multiple keloids throughout the body are extremely challenging. Keloids are highly resistant, refractory, and prone to recurrence, and are thus known as the "cancer that does not…
- Trial name
- WBUS +TCM (NCT07679243)
- Testing
- Wide-Band Ultrasound, traditional Chinese medicine
- Volunteers
- 120 people
- Sponsor
- Fujian Medical University Union Hospital