Clinical trials: Physical Dysfunction
Cognitive Dysfunction
Characteristics and Outcomes of a Capacity-to-Consent Assessment Service
Background: Many medical conditions such as Alzheimer s disease limit the ability of people to think clearly. For medical scientists to best study these medical conditions, they need to enroll some people who may not be able to…
- Trial name
- NCT03258606
- Where
- United States
- Volunteers
- 1,098 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Autism
Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism
The purpose of this study is to compare how children with autism, typically developing children, and children with other developmental delays value social attention and toys.
- Trial name
- NCT03152383
- Testing
- Training trials, Progressive Ratio Session, Re-test
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Emory University
Renal Insufficiency, Chronic
Explore New Magnetic Resonance Technology in Assessment of Renal Dysfunction
Currently, renal biopsy is the gold standard for evaluating renal pathology and renal fibrosis, but it is invasive and carries the risk of serious complications; and the sampled tissue is only a small part of the kidney, which is…
- Trial name
- NCT06366529
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Zhen Li
Children, Only, Vestibular Disorder
Vestibular and Postural Function in an Unselected Group of Children With Sensorineural Hearing Loss
The goal of this prospective cohort study is to investigate the vestibular function in children with unilateral or bilateral sensorineural hearing loss.
- Conditions
- Children, Only, Vestibular Disorder, Vestibular Function, Sensorineural Hearing Loss
- Trial name
- VASIC (NCT06229717)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Gødstrup Hospital
Hypertension, Pulmonary, Ventricular Dysfunction, Left
Confirmatory Study of IK-3001 in Japanese Subjects With Peri-/Post-op Pulmonary Hypertension Assoc. With Cardiac Surgery
Sixteen Japanese subjects (6 adults/10 children) with peri- and post-operative pulmonary hypertension associated with cardiac surgery will be evaluated at approx. 6 sites for safety and efficacy of IK-3001.
- Trial name
- NCT01959828
- Testing
- IK-3001
- Where
- 7 sites in Japan
- Volunteers
- 18 people
- Sponsor
- Mallinckrodt
Physical Activity, Endothelial Dysfunction
Recreational Physical Activity and Cardiometabolic Profile
The purpose of present study was to investigate the effect of 10 weeks of recreational physical activity program on the irisin levels, progenitor endothelial cells and cardiometabolic profile in healthy children.
- Conditions
- Physical Activity, Endothelial Dysfunction, Metabolic Syndrome x
- Trial name
- NCT02982967
- Testing
- Physical Activity
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Graft vs Host Disease, Sjogren's Syndrome
Potential of Transplanted Stem Cells to Mature Into Salivary Gland and Cheek Cells
This study will examine whether transplanted stem cells can turn into salivary gland cells in stem cell recipients. If so, stem cells might be used to restore salivary gland function in patients with Sjogren's syndrome and other…
- Trial name
- NCT00023491
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Sacro Iliac Joint Pain, Sacroiliac Disorder
Gong's Mobilization and Jone's Positional Release for SIJ Dysfunction
This study aims to compare the efficacy of Gong's mobilization and Jones's positional release technique in individuals with sacroiliac joint dysfunction.
- Conditions
- Sacro Iliac Joint Pain, Sacroiliac Disorder, Sacroiliac Joint Dysfunction
- Trial name
- NCT07580430
- Testing
- Gong's mobilization, Jone's positional release
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Elite College of Management Sciences, Gujranwala, Pakistan
Subarachnoid Aneurysm Hemorrhage, Microsurgery
Structural and Clinical Predictors of Cognitive Impairment After Surgical Treatment for Ruptured Cerebral Aneurysms
This study investigates the clinical and structural predictors of long-term cognitive impairment in patients who underwent microsurgical clipping for aneurysmal subarachnoid hemorrhage.
- Conditions
- Subarachnoid Aneurysm Hemorrhage, Microsurgery, Cognitive Impairment
- Trial name
- SCOPE-aSAH (NCT07723131)
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- University of Campinas, Brazil
Respiratory Failure, Respiratory Distress Syndrome
Ventilator Induced Diaphragm Dysfunction in Pediatric Critically Ill Patients (VIDD)
evaluation of diaphragmatic disfunction eventually occurred in pediatric patient undergoing mechanical ventilation therapy
- Conditions
- Respiratory Failure, Respiratory Distress Syndrome, Mechanical Ventilation Complication
- Trial name
- VIDD (NCT03768232)
- Testing
- ultrasound asessment
- Volunteers
- 80 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Cleft Palate, Cleft Lip
Perioperative Respiratory Adverse Events in Cleft Lip and Palate Surgery: Incidence, Risk Factors, and Clinical Scoring
Cleft lip and palate surgeries present unique anesthetic challenges due to shared airway access with the surgical field, frequent anatomical abnormalities, and a predominantly infant and toddler population.
- Conditions
- Cleft Palate, Cleft Lip, Laryngospasm, Bronchospasm
- Trial name
- NCT07651904
- Testing
- Standard General Anesthesia per Institutional Protocol
- Volunteers
- 150 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Pelvic Pain, Pelvic Floor Dysfunction
HOme PElvic Floor Improvement Trainer Trial
This study will gauge the efficacy of a home biofeedback treatment device for pelvic floor dysfunction/voiding dysfunction and pelvic pain.
- Conditions
- Pelvic Pain, Pelvic Floor Dysfunction, Voiding Dysfunction
- Trial name
- HoPe FIT (NCT06909539)
- Testing
- Home Pelvic Floor Trainer
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Cognitive Impairment, Covid19
The MentalPlus® for Assessment and Rehabilitation of Cognitive Function After Remission of the Symptoms of COVID-19
This study evaluates and rehabilitates the cognitive functions of attention, memory, visual perception, language, and executive by the mentalPlus® digital game of COVID-19 surviving patients after remission of symptoms.
- Conditions
- Cognitive Impairment, Covid19, Cognitive Dysfunction, Depression, Anxiety
- Trial name
- MP-COVID (NCT04632719)
- Testing
- The use of the MentalPlus® digital game for assessment and rehabilitation of cognitive function after remission of the symptoms of COVID-19
- Where
- 2 sites in Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Rotavirus Infections, Environmental Enteric Dysfunction
SaniVac Trial - Sanitation and Oral Rotavirus Vaccine Performance
This is a controlled cohort study to assess the effect of improved sanitation on oral rotavirus vaccine performance in low-income urban neighbourhoods of Maputo, Mozambique.
- Conditions
- Rotavirus Infections, Environmental Enteric Dysfunction, Enteric Infections
- Trial name
- NCT03313128
- Testing
- Sanitation
- Where
- Mozambique
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Post Operative Pain
Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay
The purpose of this study is to compare, the safety, efficacy and level of parent and nurse satisfaction with three methods of opioid administration post-operatively in children (4-18 years of age) with developmental delay.
- Trial name
- PNCA (NCT00743730)
- Testing
- Pain and standard side effect management for PNCA with basal method., Pain and standard side effect management with PNCA without basal, Pain and standard side effect management with IV on an as needed basis method.
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Medical College of Wisconsin
Executive Dysfunction, Physical Stress
Integrative Adolescence Research Programme (IARP)
This study aims to understand child health during adolescence. We will examine the role of lifestyle (e.g. physical activity), growth trajectories and other environmental factors that can influence the development of phenotypes…
- Conditions
- Executive Dysfunction, Physical Stress, Mental Health Wellness 1
- Trial name
- IARP (NCT06622681)
- Testing
- No intervention
- Where
- 2 sites in Singapore
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Delirium, Cognitive Impairment
Validation of the PreSchool Confusion Assessment Method for the Intensive Care Unit (psCAM-ICU)
The investigators hypothesize that critical care trained registered nurses and physicians can perform measurements of cognitive impairment in critically ill pediatric patients in a reliable and valid manner.
- Trial name
- NCT02481115
- Volunteers
- 300 people
- Sponsor
- Vanderbilt University