Clinical trials: Physical Function
Pregnancy, Smoking
Evaluating the Effects of Supplemental Vitamin C on Infant Lung Function in Pregnant Smoking Women
Women who smoke during their pregnancy place their unborn child at an increased risk of health problems, including decreased lung function and possible lung diseases later in life.
- Trial name
- NCT00632476
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Obesity
Executive Function Training in Childhood Obesity: Food Choice, Quality of Life and Brain Connectivity
This study evaluates if executive function training in obese children can improve food-related choices and produce cognitive and neuroimaging changes, but also improve psychological and physical status and quality of life…
- Trial name
- TOuCH (NCT03615274)
- Testing
- Executive function training, Psychoeducation
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- University of Barcelona
Wheezing
Montelukast in Children With Wheezing
In this study children with recurrent wheezing (>/= 2 episodes in the last 6 months)and aged less than 2 years will be enrolled as outpatients.
- Trial name
- NCT00775697
- Testing
- Montelukast
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Universita di Verona
Osteoarthritis
Comparison of Function and Fit of Standard and Gender-Specific CR High-Flex Total Knee Prostheses
The purpose of this prospective, randomized study was to compare functional outcome, radiographic results, range of motion, patients satisfaction, and fit of the femoral component in patients receiving either a standard posterior…
- Trial name
- CR (NCT00916968)
- Testing
- Standard CR-Flex total knee, Gender specific CR-Flex
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Ewha Womans University
Asthma
A Study to Compare Severe Asthma Patients Who Start Biologics and Who do Not Start (PROSPECT)
Objectives in this study is to compare the change of lung function after 24 months from baseline between the two groups; one is the patient group who decided to start biologics treatment, and another is the patient group who…
- Trial name
- NCT04808518
- Where
- 28 sites in Japan
- Volunteers
- 74 people
- Sponsor
- AstraZeneca
Stem Cell Transplantation, Hematopoietic, Poor Graft Function
Peripheral Blood Stem Cell Combined With Mesenchymal Stem Cells for Treatment of Poor Graft Function
The purpose of this study is to evaluate the utility of treating patients experiencing poor graft function after allogeneic hematopoietic stem cell transplantation with Granulocyte Colony-Stimulating Factor (G-CSF) mobilized…
- Conditions
- Stem Cell Transplantation, Hematopoietic, Poor Graft Function, Hematological Diseases
- Trial name
- NCT02083718
- Testing
- PBSC, MSCs
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Premature Birth
Brain Training in Preterm Children at Risk for Inattention, Hyperactivity, and Executive Function Impairment
The purpose of this study is to determine if different forms of child-friendly, computer-based puzzles and games ("brain training") targeting executive function (EF) skills (i.e., thinking, problem-solving) result in improvements…
- Trial name
- NCT02588391
- Testing
- Brain Training (Active), Brain Training (Passive), Brain Training (Active or Passive)
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Stanford University
Sedentary Behavior, Affect
Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
The overall objective of this in-lab randomized controlled trial is to test the efficacy of multi-day interruptions in sedentary behavior vs.
- Conditions
- Sedentary Behavior, Affect, Metabolic Disturbance, Anxiety
- Trial name
- NCT04469790
- Testing
- SIT+WALK, EX
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Adolescent Idiopathic Scoliosis, Diaphragmatic Manual Techniques
Three-Dimensional Scoliosis Exercises and Diaphragmatic Manual Techniques in Adolescents With Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional deformity of the spine that emerges during growth and is characterized by lateral curvature, vertebral rotation, and trunk asymmetry.
- Conditions
- Adolescent Idiopathic Scoliosis, Diaphragmatic Manual Techniques, Schroth Exercises
- Trial name
- NCT07683533
- Testing
- Diaphragmatic manual techniques, Schroth exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Akdeniz University
Juvenile Idiopathic Arthritis (JIA)
Short-Term Effects of Intra-Articular Corticosteroid Injection on Knee Function in Juvenile Idiopathic Arthritis
The purpose of this study is to evaluate the short-term clinical effects of intra-articular corticosteroid injections on knee joint functions in children and adolescents diagnosed with Juvenile Idiopathic Arthritis (JIA).
- Trial name
- NCT07709026
- Testing
- Intra-articular Corticosteroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Necmettin Erbakan University
Anomalous Coronary Artery Origin, Anomalous Coronary Artery Arising from the Opposite Sinus
New Patient-specific Functional Assessment of the Anomalous Aortic Origin of Coronary Arteries.
Anomalous Aortic Origin of the Coronary Arteries (AAOCA) is a rare congenital disease that may cause sudden death in young subjects.
- Conditions
- Anomalous Coronary Artery Origin, Anomalous Coronary Artery Arising from the Opposite Sinus, Anomalous Coronary Artery Course, Anomalous Coronary Artery with Aortic Origin and Course Between the Great Arteries
- Trial name
- NECESSARY (NCT05159791)
- Testing
- Invasive coronary blood flow assessment and simulations and fluid dynamic patient specific simulation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Policlinico S. Donato
Unilateral Cerebral Palsy
Mirror Therapy Versus Task Oriented Training on Hand Function in Children With Unilateral Cerebral Palsy
The purpose of the study is to compare the effect between mirror therapy and task-oriented training on hand function in children with unilateral cerebral palsy.
- Trial name
- NCT06082115
- Testing
- Selected Physical and Occupational Therapy Program, Mirror Therapy, Task-Oriented Training
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Duchenne Muscular Dystrophy
Relationship Between PFTs and Pdi in DMD
A cross-sectional study to explore the relationship between clinically assessed pulmonary function test (PFT) measures and transdiaphragmatic (Pdi) measures in Duchenne muscular dystrophy (DMD) as well as to explore the…
- Trial name
- NCT03335384
- Testing
- Esophageal Balloon, Gastric Balloon, Nasal Pressure Transducer
- Sponsor
- University of Minnesota
Breast Cancer, Upper Extremity
Arm Exercise Capacity and Maximal Oxygen Consumption With Breast Cancer
Breast cancer is the most common type of cancer among women worldwide. The incidence rate has reached approximately 16%. According to 2016 data from the Ministry of Health, the incidence of breast cancer in Turkey is 46.8 per…
- Conditions
- Breast Cancer, Upper Extremity, Oxygen Consumption, Healthy
- Trial name
- NCT06018038
- Testing
- Arm Exercise Capacity, Peak Oxygen Consumption (VO2peak), Muscle oxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Kidney Disease, Neoplasm
Oxaliplatin in Cancer Patients With Impaired Kidney Function
Oxaliplatin is an experimental anti-cancer drug that can shrink tumors such as colon cancer. However, because this drug can damage the kidneys, it is necessary to determine what doses of the drug can safely be given to patients…
- Conditions
- Kidney Disease, Neoplasm, Neoplasm Metastasis
- Trial name
- NCT00001835
- Testing
- Oxaliplatin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute (NCI)
Bone Marrow Diseases, Lymphoma
Thromboelastography, Platelet Function and Platelet Recovery in Haemato-oncologic Patients With Thrombocytopenia
This is a prospective observational clinical study to characterise abnormalities of thromboelastography (TEG) parameters in patients with chemotherapy-induced thrombocytopenia.
- Trial name
- NCT01928017
- Where
- Norway
- Volunteers
- 13 people
- Sponsor
- University of Bergen
Epilepsy
STEP: Enhanced Physical Activity in Children and Youth With Epilepsy
Epilepsy is common in childhood. Children with epilepsy are at increased risk of impaired health, functioning, psychological well-being, and quality of life.
- Trial name
- STEP (NCT01550874)
- Testing
- Physical activity behavior-change counselling
- Where
- 2 sites in Canada
- Volunteers
- 122 people
- Sponsor
- McMaster University
E Cigarette Use
Novel Pulmonary Imaging of Lung Structure and Function in E-cigarette Smokers
This is a longitudinal study of the long-term health impact of e-cigarette smoking on the lungs. Participants will be followed over a period of 5 years, and impacts of e-cigarette smoking on the lungs will be measured with…
- Trial name
- NCT04616313
- Testing
- Hyperpolarized Xenon-129 MRI of the lungs, Computed Tomography (CT), Pulmonary Function Tests (PFT)
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Acute Respiratory Distress Syndrome
Impact of the Transpulmonary Pressure on Right Ventricle Function in Acute Respiratory Distress Syndrome
Pulmonary distension induced by mechanical ventilation physiologically alters right ventricle pre and after-load, hence might lead to right ventricle failure.
- Trial name
- VD-SDRA (NCT04184674)
- Testing
- Pneumotachograph, Esophageal catheter, Transthoracic and / or transesophageal cardiac ultrasound
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infection
Safety Assessment of Lactobacillus Salivarius CECT5713 in 6 Months Old Children
The aim of the trial is to evaluate safety of a follow on formula supplemented with Lactobacillus salivarius CECT5713. A randomized double blind placebo controlled trial was carried out.
- Trial name
- P010 (NCT00724204)
- Testing
- follow on formula without probiotics, follow on formula with Lactobacillus salivarius CECT5713
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Puleva Biotech
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