Clinical trials: Physical Function
Cerebral Palsy, Muscle Contracture
The Muscle in Cerebral Palsy; Sarcomere Length in Vivo and Microscopic Characterization of Biopsies.
Cerebral palsy (CP) is a motor impairment due to a brain malformation or a brain lesion before the age of two. Spasticity, hypertonus in flexor muscles, dyscoordination and an impaired sensorimotor control are cardinal symptoms.
- Conditions
- Cerebral Palsy, Muscle Contracture, Spasticity, Muscle
- Trial name
- CPMuscleSL (NCT05518565)
- Testing
- No intervention
- Where
- 3 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Eva Ponten
Patent Ductus Arterioses
The Impact of Platelet Functions on Spontaneous Ductal Closure in Preterm Infants
Although thrombocytopenia has been reported as a risk factor for patent ductus arterioses, there is lack of data on the function of platelets in ductal closure.
- Trial name
- PFA100 (NCT02010879)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara University
Lung Cancer, Thoracic Cancer
Exploring Robotic-assisted Thoracic Surgery for Lung Cancer
Background Surgery for lung cancer can be performed using open (thoracotomy) or minimally invasive techniques (Video Assisted Thoracic Surgery (VATS)).
- Conditions
- Lung Cancer, Thoracic Cancer, Surgery
- Trial name
- ROSE (NCT03658083)
- Testing
- Thoracotomy, Robotic-assisted thoracic surgery
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people
- Sponsor
- Teesside University
Anorexia Nervosa
Lung Function Tests in Adolescents With Anorexia Nervosa
The investigators hypothesize that lung function would be adversely affected at the hypocaloric stage of adolescents suffering from anorexia nervosa.
- Trial name
- NCT00942929
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Bleeding Disorders, Iron
Impact of IV Iron on Bleeding Symptoms in Iron Deficient Patients With Inherited Bleeding Disorders
This is a prospective, single-arm, single-center observational study evaluating the impact of intravenous (IV) iron replacement in patients with inherited bleeding disorders and iron deficiency (ferritin <50ng/dL).
- Conditions
- Bleeding Disorders, Iron, Platelet, Bleeding
- Trial name
- IRON-BD (NCT07083583)
- Testing
- IV Iron (standard of care)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nicoletta C Machin
Cerebral Palsy
FES in Young Children With Perinatal Stroke
Every year about 1 out of every 1,600-5,000 infants has a stroke around the time of birth. Many of these children will have lifelong physical problems. For example, the arm muscles are often paralyzed.
- Trial name
- NCT02975180
- Testing
- FES, Conventional
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University Health Network, Toronto
Depression
Reward-Related Processes and Brain Function
This study will examine and compare brain changes during decision-making in healthy adolescents and adolescents who are anxious or depressed.
- Trial name
- NCT00029588
- Where
- 2 sites in United States
- Volunteers
- 241 people
- Sponsor
- National Institute of Mental Health (NIMH)
Anemia Acute, Fatigue
ABC - A Post Intensive Care Anaemia Management Trial
On discharge from intensive care (ICU) patients are often severely anaemic (have a low level of haemoglobin (Hb) in their red blood cells (RBC)). Anaemia can persist for many months making patients feel tired and fatigued.
- Conditions
- Anemia Acute, Fatigue, Physical Disability, Quality of Life
- Trial name
- NCT04591574
- Testing
- Red Blood Cells (Transfusion)
- Where
- United Kingdom
- Volunteers
- 346 people
- Sponsor
- University of Edinburgh
Pregnancy, Childbirth and Puerperal Disorders
Effects of Pregnancy and Childbirth on Pelvic Floor Morphology and Sexual Function in Egyptian Women
To evaluate levator ani muscle morphology following normal vaginal delivery and cesarean section (elective and emergent), using three-dimensional (3D) transperineal ultrasound, and to study the effect of mode of delivery on…
- Trial name
- NCT02245386
- Testing
- transperineal pelvic floor ultrasound
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Development and Health
Fish Oil Supplementation in Lactation
The main purpose of the study was to examine whether fish oil supplementation of lactating mothers affect infant development during first year of life, focusing on visual and mental development.
- Trial name
- NCT00266305
- Testing
- Fish oil (Dry n-3, BASF)
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Acetabular Fracture
Function Outcome of Impaction Injuries in Acetabular Fractures
Is the anatomical reduction of osteochondral impaction in the acetabular fractures will improve the functional outcome? Despite the increasing amount of literature related to the management of anteromedial dome impactions and…
- Trial name
- NCT03152266
- Testing
- No intervention. Observational study
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Neck Pain
Effects of Resistance Training on Pain, Function and Work Ability in Patients With Moderate to Severe Neck Pain
The purpose of this study is to investigate if high-intensity resistance training can induce additional beneficial effects, for patients with moderate to severe long term pain in the neck, when added to a multidisciplinary…
- Trial name
- NCT02420197
- Testing
- High-intensity resistance training, General physical activity, Multidisciplinary rehabilitation program
- Where
- Norway
- Volunteers
- 74 people
- Sponsor
- Norwegian University of Science and Technology
Bronchopulmonary Dysplasia
Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia
The purpose of this study is to determine if late doses of Infasurf surfactant given when patients are receiving inhaled nitric oxide will interact to improve surfactant function and increase survival without BPD in treated…
- Trial name
- TOLSURF (NCT01022580)
- Testing
- Infasurf surfactant (ONY, Inc.)
- Where
- 21 sites in United States
- Volunteers
- 511 people
- Sponsor
- Roberta Ballard
Epilepsy
Assessment of Kidney Function in Patients With Epilepsy
This observational cross-sectional study aims to assess kidney function in pediatric patients with epilepsy attending Sohag University Hospital.
- Trial name
- NCT07288788
- Testing
- Standard Clinical Observation
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
High Intensity Laser, Shoulder Impingement Syndrome
Effect of High Intensity Laser on Shoulder Impingement.
Treatment for shoulder impingement is conservative initially, Rehabilitation programs generally consist of exercise therapy and manual therapy that provide relief from symptoms of impingement.
- Conditions
- High Intensity Laser, Shoulder Impingement Syndrome, Shoulder Pain
- Trial name
- lasershoulder (NCT06732570)
- Testing
- high intensity laser, manual therapy, exercise therapy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
PCOS
Theca Cell Function in Adolescents With Polycystic Ovary Syndrome (PCOS)
In women with polycystic ovary syndrome (PCOS), the cardinal physiological abnormality is excessive ovarian androgen production marked by increased serum testosterone (T) and androstenedione (A) levels.
- Trial name
- NCT01154192
- Testing
- Dexamethasone, recombinant human chorionic gonadotropin (r-hCG)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Minimal Hepatic Encephalopathy
Study of Lactulose in Children With Chronic Liver Disease
Pediatric patients with chronic liver disease may have Minimal Hepatic Encephalopathy(MHE)which can cause changes in behavior,intelligence and neurological function.By utilizing cognitive and developmental testing we will…
- Trial name
- MHE (NCT00811434)
- Testing
- Lactulose
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Indiana University
Cystic Fibrosis
Combined Inspiratory Muscle and 'Whole Muscle' Training in Children With Cystic Fibrosis
To study the effects of an 8-week combined inspiratory muscle training and exercise (resistance+aerobic) program on of a lung volume, inspiratory muscle strength (maximal inspiratory pressure, PImax) and cardiorespiratory fitness…
- Trial name
- NCT01706445
- Testing
- Other
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Europea de Madrid
Monogenic Obesity
A Study Evaluating Mibavademab Treatment of Obesity Due to Leptin (LEP) Gene Mutations in Children, Adolescents and Adults
This study is researching an experimental drug called mibavademab. The study is focused on patients with a condition called monogenic obesity.
- Trial name
- NCT07220772
- Testing
- Mibavademab
- Where
- 3 sites in Germany, Turkey (Türkiye)
- Volunteers
- 4 people
- Sponsor
- Regeneron Pharmaceuticals
Urethral Obstruction
Standardized Prenatal Clinical Care for LUTO
The investigators propose a standardized prenatal management, based on the scientific evidence published in the literature, to manage prenatally fetuses with lower urinary tract obstruction (LUTO).
- Trial name
- NCT02315521
- Testing
- Fetal Intervention for LUTO
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine
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