Clinical trials: Physical Functioning
Cerebral Palsy
Fully Immersive Virtual Reality Applications in Children With Cerebral Palsy
This study was conducted in children diagnosed with Cerebral Palsy (CP); It is a prospective randomized clinical study planned to examine the effects of treadmill and bicycle ergometer applications combined with fully immersive…
- Trial name
- NCT06428292
- Testing
- Virtual reality device branded ''Meta Quest 2''
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Omer Ayhan
Cystic Fibrosis (CF), Primary Ciliary Dyskinesia (PCD)
Exercise Capacity, Muscle Oxygenation, Respiratory Muscle Strength, and Physical Activity Level in Pediatric CF and PCD
Cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) are genetic diseases characterized by chronic respiratory tract infections.
- Trial name
- NCT07157644
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Gazi University
Prostatic Neoplasms, Genital Neoplasms, Male
MRI for Assessment of Hypoxia-Induced Prostate Cancer Aggressiveness
The purpose of the study is to combine and correlate data from morphological and functional MRI, molecular signatures of tumor hypoxia, the presence of micrometastases and tumor hypoxia with the goal being predicting of prostate…
- Conditions
- Prostatic Neoplasms, Genital Neoplasms, Male, Prostatic Diseases
- Trial name
- FuncProst (NCT01464216)
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Cerebral Palsy, Child, Preschool
Effect of Power Wheelchairs on the Development and Function of Young Children With Severe Physical Disabilities
Self-produced locomotion often is limited in children with cerebral palsy and other conditions that cause severe motor impairments.
- Trial name
- NCT01115998
- Testing
- Power wheelchair, No power wheelchairs
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Oklahoma
Ewing Sarcoma, Osteosarcoma
Osteosarcoma and Ewing Sarcoma Treatment Response Assessment With Functional MRI Imaging in Children and Young Adults
The purpose of the study was to investigate whether functional MRI imaging (diffusion weighted imaging) is useful for monitoring the therapeutic response of bone sarcomas in children and young adults.
- Trial name
- FUBEO (NCT01780779)
- Testing
- MRI
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Healthy
Tongue Muscular Assessment in Healthy Children
This study aims to obtain normative values for tongue motor functions in healthy children.
- Trial name
- TMAC (NCT06166680)
- Testing
- Sleep quality assessment, Anthropometry, Tongue strength assessment
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Effect of Superstarch on Soccer Performance
Superstarch and Physical/Cognitive Performance Following a Simulated Soccer Game
To assess the efficacy of a hydrothermally modified starch supplement (Superstarch made byGeneration UCAN) vs isoenergetic placebo (glucose) on exercise performance, execution of specific soccer skills, and on cognitive function…
- Trial name
- NCT02667340
- Testing
- Superstarch
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Sickle Cell Disease
Sickle Cell Children's Exercise Study (SuCCESs)
The Sickle Cell Children's Exercise Study (SuCCESs) will explore the feasibility and effects of a moderate intensity strengthening, balance, speed, and agility intervention program in children with sickle cell disease.
- Trial name
- SuCCESs (NCT06074198)
- Testing
- SuCCESs
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Maryland, Baltimore
Shoulder Pain, Shoulder Mobility Impairment
Burden and Outcome of Shoulder Disorders in Primary Health Care
Consumption of medical care and outcome of shoulder pain and disability in primary care.
- Trial name
- NCT01300091
- Where
- Finland
- Sponsor
- Central Finland Hospital District
Adolescent Idiopathic Scoliosis
Assessment of Respiratory Parameters, Aerobic Capacity and Sleep Quality in Thoracic AIS
This study aims to compare respiratory parameters -including pulmonary function and respiratory muscle strength-as well as aerobic capacity and sleep quality in individuals with thoracic adolescent idiopathic scoliosis.
- Trial name
- NCT07187271
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Uskudar University
Pediatric Critical Illness; Physical Function Assessment; Functional Status; Rehabilitation
Validity of the Children's Chelsea Critical Care Physical Assessment Tool (cCPAx-TR) in Turkish Pediatric Intensive Care Patients
This single-center, prospective observational study aims to translate, culturally adapt, and evaluate the validity and reliability of the Children's Chelsea Critical Care Physical Assessment Tool (cCPAx) in Turkish pediatric…
- Trial name
- NCT07241455
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medeniyet University
Pediatric Brain Tumor, Cognitive Impairment
Fitness to Aid the Brain and Cognitive Skills
The study will assess the feasibility of a pilot clinical trial of community-led aerobic exercise training for paediatric brain tumour survivors (PBTS) and the feasibility of a web-based platform to deliver this exercise…
- Trial name
- Fit ABCS (NCT05367076)
- Testing
- Web-based Aerobic Exercise Program
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- The Hospital for Sick Children
Spinal Muscular Atrophy (SMA), Neuromuscular Disease
Ultrasonographic Muscle Assessment and Functional Scales in Spinal Muscular Atrophy
This study aims to investigate the relationship between ultrasonographic muscle thickness measurement and echogenicity assessment with functional scales in children with spinal muscular atrophy (SMA).
- Trial name
- NCT06599606
- Testing
- Ultrasonographic Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Sickle Cell Disease
Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease
Background: Sickle cell disease (SCD) is a blood disease. The drug hydroxyurea (HU) is approved to prevent pain crises in people with SCD. Researchers want to see how higher doses of HU affect the blood.
- Trial name
- NCT02225132
- Testing
- Hydroxyurea
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Familial Mediterranean Fever
A Diagnostic Test for Familial Mediterranean Fever
Familial Mediterranean Fever (FMF) is the most common auto-inflammatory disease (prevalence: 1-5 / 10,000 inhabitants). It is due to mutations of the MEFV gene, encoding variants of the Pyrin inflammasome.
- Trial name
- DEPIST-FMF (NCT03747315)
- Testing
- In vitro functional test
- Where
- 4 sites in France
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Lower Urinary Tract Symptoms, Skeletal Muscle
Examining the Relationship Between Core Muscles and Bladder Issues in Children
The goal of this observational study is to learn about functional bladder problems in children. The main questions it aims to answer are: Does bladder symptoms in children have an effect on core muscles? How do core muscles…
- Trial name
- NCT06317116
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Bakircay University
Juvenile Huntington Disease, Juvenile-Onset Huntington Disease
Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
The goal of this observational study is to learn about brain development in Juvenile-onset Huntington's Disease (JoHD). The main questions it aims to answer are: Is brain development different in JoHD than Adult-onset…
- Trial name
- NCT05707663
- Where
- 5 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Iowa
MYT1L Syndrome
MYT1L Syndrome: a Rare Paediatric Genetic Syndrome Responsible for a Neurodevelopmental Disorder
MYT1L syndrome is a rare genetic syndrome, recently described in 2011, with paediatric onset, responsible for a neurodevelopmental disorder combining psychomotor retardation, learning difficulties and/or intellectual development…
- Trial name
- MYT1L (NCT07008612)
- Testing
- Patients with a genetic syndrome linked to the MYT1L gene, Patients with a neurodevelopmental disorder of genetic origin but not linked to MYT1L
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Rouen
Resistance Exercise, Muscle Hypertrophy
Muscle Adaptations in Children and Adults Following Twelve Weeks of Flywheel or Weight Stack Resistance Exercise
The goal of this trial is to compare resistance exercise using traditional techniques and flywheel training to controls in healthy children ages nine to 13 and adults ages 18 to 50.
- Conditions
- Resistance Exercise, Muscle Hypertrophy, Skeletal Muscle, EMG
- Trial name
- KidREx (NCT06698055)
- Testing
- Flywheel Resistance Exercise, Weight Stack Resistance Exercise
- Where
- Sweden
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Björn Alkner
Children, Overweight
The Odense Overweight Intervention Study
Strong and consistent evidence have shown that overweight, including obesity, is an important risk factor for the development of cardiovascular disease (CVD) in adults.
- Conditions
- Children, Overweight, Obesity, Metabolic Syndrome
- Trial name
- OOIS (NCT01574352)
- Testing
- Small intervention, Intervention camp
- Where
- 2 sites in Denmark
- Volunteers
- 115 people
- Sponsor
- University of Southern Denmark