Clinical trials: Physiological Conditions
Parkinson Disease, Dystonia
Physiological Brain Atlas Development
Enrollment of candidates undergoing a deep brain stimulator (DBS) implant.
- Conditions
- Parkinson Disease, Dystonia, Tremors, Obsessive Compulsive Disorder
- Trial name
- NCT01210534
- Testing
- No intervention
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- Ohio State University
Infant Development, Premature
Hammock Position and Kangaroo Care
This study was planned to evaluate the effectiveness of two positions that may have an effect on pain, stress, comfort and physiological parameters in premature infants.
- Trial name
- NCT06436404
- Testing
- Hammock intervention, Kangaroo care intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Stable Angina, Unstable Angina
International Collaboration of Comprehensive Physiologic Assessment
The current study evaluated prognostic implication of comprehensive physiologic assessment using fractional flow reserve, coronary flow reserve (CFR) and index of microcirculatory resistance (IMR).
- Conditions
- Stable Angina, Unstable Angina, Non-ST Elevation Myocardial Infarction, ST-segment Elevation Myocardial Infarction
- Trial name
- NCT03690713
- Testing
- Fractional flow reserve, coronary flow reserve, and index of microcirculatory resistance
- Where
- 4 sites in Japan, South Korea and 1 more
- Volunteers
- 1,397 people
- Sponsor
- Seoul National University Hospital
Pneumonia
Effect of Pursed-Lip Breathing on Physiological Parameters and Discharge Readiness in Children With Pneumonia
This study aims to evaluate the effects of Pursed-Lip Breathing (PLB) exercises on physiological parameters (such as respiratory rate, heart rate, and oxygen saturation) and discharge readiness in children diagnosed with…
- Trial name
- PLB-PEDPNEU (NCT07106203)
- Testing
- Pursed-Lip Breathing (PLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Ataturk University
Infant, Newborn, Weight Loss
Effect of Kangaroo Care on Phyiological Weight Loss in Term Newborns
The aim of the study is to evaluate the effect of kangaroo care on physiological weight loss in term newborns.
- Trial name
- NCT05001334
- Testing
- Kangaroo care training
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Istanbul University
No Applicable Condition; Study of Physiologic Monitor Alarms
Quality Improvement - Monitoring Alarm Optimization Study
This project aims to reduce the frequency of duplicate, false and clinically insignificant alarms in hospital units, and subsequent alarm fatigue resulting from excessive alarm frequency.
- Trial name
- QI-MAOS (NCT02916212)
- Testing
- Optimized alarm profiles
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Stunting, Severe Acute Malnutrition
Changes in Nerve Electro Physiologic Properties in Children Before and After Correction of Malnutrition
The goal of this clinical trail study is to measure neurophysiologic parameters to assess the effect of malnutrition on the peripheral nervous system and their response to treatment in three categories (SAM, severe wasting, and…
- Conditions
- Stunting, Severe Acute Malnutrition, Wasting
- Trial name
- NCT05891457
- Testing
- Nutritional Intervention
- Where
- Bangladesh
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Tracheostomy, Care
The Effects of Listening to Fairy Tales, Listening to Fairy Tales in Their Mothers' Voices, and Watching Cartoons on Pain, Comfort Levels, and Physiological Parameters During Tracheostomy Care in a Palliative Care Clinic
This study aimed to determine the effects of listening to fairy tales, listening to fairy tales from the mother's voice, and watching cartoons on pain, comfort, and physiological parameters during tracheostomy care of children…
- Trial name
- NCT07210346
- Testing
- fairy tales, mother's voice, Cartoons
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Ataturk University
Craniosynostoses, Hypovolemia
Hemodynamic Monitoring During Craniosynostosis Surgery: Comparing Traditional and Newer Technology Monitors (CRASY-PRAM)
Hemodynamic evaluation during pediatric anesthesia is essential to care management. Intraoperative cardiovascular instability is frequent in major surgeries, and appropriate monitoring is necessary to ensure safe anesthetic…
- Conditions
- Craniosynostoses, Hypovolemia, Hemorrhage, Hemodynamic Instability
- Trial name
- CRASY-PRAM (NCT06263075)
- Testing
- Intraoperative monitoring
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Surgical Infants on NG/NJ/J/G-tube Feeds, Tracheoesophageal Fistula
A Physiological Study to Determine the Enteral Threonine Requirements in Infants Aged 1 to 6 Months
This is the 5th in a series of physiological studies to determine the amino acid requirements of infants. There have been 4 studies to determine tyrosine, methionine, threonine and lysine requirements in infants when they are fed…
- Conditions
- Surgical Infants on NG/NJ/J/G-tube Feeds, Tracheoesophageal Fistula, Pierre-Robin Syndrome, Diaphragmatic Hernia
- Trial name
- INFORALTHR (NCT02364843)
- Testing
- Amino Acid: Threonine
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- The Hospital for Sick Children
EEG
Behavioural and Physiological Measures of Young Students With Dyslexia
The proposed is reading intervention study to track neural changes in the brain. Students with dyslexia will participate in a reading study.
- Trial name
- NCT05376696
- Testing
- Set For Variability, Current Best Practices
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University
Fatigue
Effect of Myofascial Release on Post-Exercise Recovery in Water Polo Athletes
Objective: To assess the acute effect of a myofascial release protocol applied to the adductor muscles of the thigh on functional, biomechanical, and physiological variables.
- Trial name
- NCT06933446
- Testing
- Myofascial Release, Classic Massage
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Luis Gustavo Lizi Jorge
Syncope, Chest Pain
Autonomic Monitoring in Neurocardiogenic Syncope
This is a prospective observational pilot study of suitability of autonomic monitoring via the VU-AMS device for prediction of neurocardiogenic syncope (NCS) in children referred to cardiopulmonary exercise testing (CPET) for a…
- Conditions
- Syncope, Chest Pain, Dyspnea
- Trial name
- ANSS (NCT05907018)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pain, Infant ALL
Effect of Leg and Heel Massage on Pain During Heel Blood Collection Newborns
This study was planned to evaluate the effect of leg and heel massage on newborns, the pain experienced during heel blood collection, and the effects on physiological parameters.
- Trial name
- NCT06567093
- Testing
- Baby Foot and Leg Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Umbilical Cord Clamping, Congenital Diaphragmatic Hernia
Physiological Umbilical Cord Clamping in Patients With Congenital Diaphragmatic Hernia. Clinical Trial
Congenital diaphragmatic hernia (CDH) is a malformation that affects 1 in every 3000 newborns. The diaphragm does not complete its closure during embryogenesis, which allows the abdominal organs to herniate into the thoracic…
- Conditions
- Umbilical Cord Clamping, Congenital Diaphragmatic Hernia, Delayed Umbilical Cord Separation
- Trial name
- NCT06408376
- Testing
- Physiological cord clamping
- Where
- Argentina
- Volunteers
- 80 people
- Sponsor
- Hospital JP Garrahan
Neurofibromatosis Type 1
A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)
Background: Neurofibromatosis type 1 (NF1) is a genetic condition that causes tumors to grow along the nerves in the skin, brain, and other parts of the body.
- Trial name
- NCT06507748
- Testing
- AlgometRx Nociometer(R)
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- National Cancer Institute (NCI)
Asthma
Effect of Montelukast on the Airway Remodeling
The distal lung contributes to asthmatic airway remodeling which is observed from early onset of the disease. Cysteinyl leukotrienes (CysLT) play important role in the pathogenesis of airway remodeling and antileukotrienes work…
- Trial name
- NCT00699062
- Testing
- singular
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Chinese Academy of Medical Sciences
Hyperbilirubinemia
Effect of Vitamin-D as an Adjuvant to Phototherapy in Reduction of Indirect Serum Bilirubin
The study aimed at filling the gaps by evaluating the effectiveness of vitamin-D as an adjuvant to phototherapy in reduction of indirect serum bilirubin among neonates with exaggerated physiological hyperbilirubinemia.
- Trial name
- NCT07098234
- Testing
- Vitamin D3, Phototherapy
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Muhammad Aamir Latif
Tremor
Effect of Alcohol on Tremors
Tremors are involuntary movements of a part or parts of the body that occur because of alternating contraction and relaxation of muscles. The causes behind most tremors are poorly understood.
- Trial name
- NCT00001925
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Physical Activity
Effect of Using a Bionic Leg on Physiological and Biomechanical Measures in Stroke Patients
This study will assess the effect of wearing a wearable bionic leg, on the physiological cost index and biomechanical measures in patients with stroke.
- Conditions
- Stroke, Physical Activity, Gait, Hemiplegic
- Trial name
- NCT03588663
- Testing
- Baseline Bionic Leg Assessment, Baseline Control Condition Assessment, Training
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- University of Winchester